97771-05-6

Basic information

• Product Name: benzo[1,3]dioxol-5-yl-benzylamino-acetonitrile
• Synonyms: benzo[1,3]dioxol-5-yl-benzylamino-acetonitrile
• CAS NO: 97771-05-6
• Molecular Weight: 266.299
• Mol File: 97771-05-6.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: benzo[1,3]dioxol-5-yl-benzylamino-acetonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: benzo[1,3]dioxol-5-yl-benzylamino-acetonitrile(97771-05-6)
• EPA Substance Registry System: benzo[1,3]dioxol-5-yl-benzylamino-acetonitrile(97771-05-6)

Safety Data

• Hazardous Substances Data: 97771-05-6(Hazardous Substances Data)

Upstream product

• 120-57-0 piperonal 
• 7677-24-9 trimethylsilyl cyanide 
• 100-46-9 benzylamine 
• 143-33-9 sodium cyanide 
• 151-50-8 potassium cyanide 

Downstream Products

• 271583-44-9 2-benzo[1,3]dioxol-5-yl-2-benzylamino-acetamide 
• 271583-27-8 benzo[1,3]dioxol-5-yl-benzylamino-acetic acid 
• 39533-43-2 amino-benzo[1,3]dioxol-5-yl acetic acid 

Relevant articles and documents

Sulfamic acid catalyzed direct condensation of aldehydes, amines, and TMSCN to α-aminonitriles at ambient temperature

A simple and efficient method has been developed for the synthesis of α-aminonitriles by a one-pot three-component condensation of aldehydes, amines, and trimethylsilyl cyanide in the presence of a catalytic amount of sulfamic acid at room temperature. Georg Thieme Verlag Stuttgart.

A facile synthesis of substituted phenylglycines

A convenient scaleable process for the preparation of substituted phenylglycines 2 by a modified Strecker reaction is described. Bisulfite- mediated addition of benzylamine and cyanide anion to substituted benzaldehydes 3 gave the aminonitriles 4 which were hydrolysed in two steps to the N-protected amino acid 1. Debenzylation using catalytic transfer hydrogenation gave the title compounds in good yield.