98035-61-1Relevant articles and documents
2,2-Dimethyl-2-(o-nitrophenyl)acetyl (DMNA) as an assisted cleavage protecting group for amines
Jiang, Yongying,Zhao, Jun,Hu, Longqin
, p. 4589 - 4592 (2007/10/03)
2,2-Dimethyl-2-(o-nitrophenyl)acetyl group (DMNA) was explored as an assisted cleavage protecting group for amines and a one-step deprotection condition was developed for its efficient removal using hydrogenation in the presence of Pd-C or PtO2 catalyst and 10% HOAc in MeOH. DMNA was found to be especially useful for the synthesis of gem-diamino compounds using Hofmann rearrangement.
Unique sequence in deltorphin C confers structural requirement for δ opioid receptor selectivity
Lazarus, LH,Salvadori, S,Grieco, P,Wilson, WE,Tomatis, R
, p. 791 - 797 (2007/10/02)
A series of deltorphin C (H-Tyr-D-Ala-Phe-Asp-Val-Val-Gly-NH2) analogues were synthesized to assess the consequences of changing anionic and hydrophobic residues on δ receptor selectivity.Analogues with altered C-terminal groups, inverted sequences, or es