98061-25-7

Basic information

• Product Name: Pyridine, 2-(2,6-dimethoxyphenyl)-
• CAS NO: 98061-25-7
• Molecular Formula: C13H13NO2
• Molecular Weight: 215.252
• Mol File: 98061-25-7.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: Pyridine, 2-(2,6-dimethoxyphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Pyridine, 2-(2,6-dimethoxyphenyl)-(98061-25-7)
• EPA Substance Registry System: Pyridine, 2-(2,6-dimethoxyphenyl)-(98061-25-7)

Safety Data

• Hazardous Substances Data: 98061-25-7(Hazardous Substances Data)

Upstream product

• 67-56-1 methanol 
• 1008-89-5 2-phenylpyridine 
• 109-04-6 2-bromo-pyridine 
• 23112-96-1 (2,6-dimethoxyphenyl)boronic acid 
• 109-09-1 2-chloropyridine 
• 5029-67-4 2-iodopyridine 
• 151-10-0 1,3-Dimethoxybenzene 

Downstream Products

• 1008-89-5 2-phenylpyridine 
• 334977-46-7 1,3-dimethoxy-2-(pyrid-2-yl)-4-bromobenzene 
• 879005-55-7 C₃₇H₃₅N₃O₈ 
• 879005-46-6 2-(2,6-dihydroxyphenyl)pyridine 

Relevant articles and documents

Palladium-catalyzed selective ortho C–H alkoxylation at 4-aryl of 1, 4-disubstituted 1, 2, 3-triazoles

The ortho- C–H bonds at C(4)-aryl of 1, 4-disubstituted 1, 2, 3-triazoles were regioselectively alkoxylated in good to excellent yields with under the directing of the triazole ring. Some products were found to exhibit strong antifungal capacity to fight against root-rot disease of Panax notoginseng by testing the minimum inhibitory concentration (MIC).

Palladium-catalyzed ortho-alkoxylation of 2-aryl-1,2,3-triazoles

Palladium-catalyzed alkoxylation of 2-aryl-1,2,3-triazoles was described in the presence of various groups in the aromatic rings. In addition, some other directing groups of heterocycles containing nitrogen were explored.

Palladium catalyzed Suzuki-Miyaura coupling with aryl chlorides using a bulky phenanthryl N-heterocyclic carbene ligand

A novel bis-phenanthryl N-heterocyclic carbene (NHC) based palladium acetate catalyst was effective for the coupling of various aryl and vinyl chlorides with organoboron compounds. N,N-Bis-(2,9-dicyclohexyl-10-phenanthryl)- 4,5-dihydroimidazolium chloride 8 (H2ICP·HCl) with Pd(OAc)2 and KF·18-c-6 in THF at room temperature gave Suzuki-Miyaura coupling of aryl and vinyl chorides, including unactivated and di-ortho substituted substrates in high yields. Hindered tri- and tetra-ortho substituted products were also efficiently produced. Benzyl chloride was also found to be a useful coupling partner and trimethylboroxine was used to give methylated products. The effect of ligand, base, temperature, solvent, and reaction time are reported along with various substrates including halides and triflates.