98062-25-0

Basic information

• Product Name: tert-butyl 2-(3,4-dimethoxyphenyl)ethylcarbamate
• Synonyms: tert-butyl 2-(3,4-dimethoxyphenyl)ethylcarbamate
• CAS NO: 98062-25-0
• Molecular Formula: C₁₅H₂₃NO₄
• Molecular Weight: 281.34742
• Mol File: 98062-25-0.mol
• Article Data: 24

Chemical Properties

• Appearance: /
• CAS DataBase Reference: tert-butyl 2-(3,4-dimethoxyphenyl)ethylcarbamate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl 2-(3,4-dimethoxyphenyl)ethylcarbamate(98062-25-0)
• EPA Substance Registry System: tert-butyl 2-(3,4-dimethoxyphenyl)ethylcarbamate(98062-25-0)

Safety Data

• Hazardous Substances Data: 98062-25-0(Hazardous Substances Data)

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 120-20-7 2-(3,4-dimethoxyphenyl)-ethylamine 
• 37034-31-4 N-(tert-butoxycarbonyl)dopamine 
• 74-88-4 methyl iodide 
• 67191-53-1 N-(3,4-Dimethoxyphenethyl)propionamide 
• 120-14-9 3,4-dimethoxy-benzaldehyde 
• 4230-93-7 3,4-dimethoxynitrostyrene 

Downstream Products

• 106469-78-7 tert-butyl (2-bromo-4,5-dimethoxyphenethyl)carbamate 
• 163276-43-5 N-(Boc)-4',5'-dimethoxy-2'-thiocyanatophenethylamine 
• 630417-46-8 allyl-[2-(3,4-dimethoxy-phenyl)-ethyl]-carbamic acid tert-butyl ester 
• 630417-48-0 {2-allyl-1-[2-(tert-butyl-diphenyl-silanyloxy)-ethyl]-6,7-dimethoxy-1,2,3,4-tetrahydro-isoquinolin-1-yl}-methanol 
• 630417-49-1 2-allyl-1-[2-(tert-butyl-diphenyl-silanyloxy)-ethyl]-1-ethynyl-6,7-dimethoxy-1,2,3,4-tetrahydro-isoquinoline 
• 106469-85-6 C₂₄H₂₇NO₃Se 
• 106469-82-3 {2-[2-(9-Hydroxy-3,3-dimethyl-1,5-dioxa-spiro[5.5]undec-7-en-9-yl)-4,5-dimethoxy-phenyl]-ethyl}-carbamic acid tert-butyl ester 
• 839673-82-4 1-(2'-bromobenzyl)-N-tert-butyloxycarbonyl-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline 
• 1262680-72-7 tert-butyl 3,4-dimethoxyphenethylbut-2-ynylcarbamate 
• 1314098-76-4 N-(tert-butoxycarbonyl)-2-(2-iodo-4,5-dimethoxyphenyl)ethylamine 
• 155974-00-8 ivabradine 
• 1325209-23-1 N-{[(7S)-3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]methyl}-N'-[2-(3,4-dimethoxyphenyl)ethyl]-N-methyl-1,3-propanediamine 
• 1325209-24-2 N-{3-[{[(7S)-3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]methyl}-(methyl)amino]propyl}-N-[2-(3,4-dimethoxyphenyl)ethyl]-2-hydroxyacetamide 
• 1325209-25-3 2-{{3-[{[(7S)-3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]methyl}(methyl)-amino]propyl}-[2-(3,4-dimethoxyphenyl)ethyl]amino}-2-oxoethyl acetate 

Relevant articles and documents

Easy access to drug building-blocks through benzylic C-H functionalization of phenolic ethers by photoredox catalysis

A visible light-mediated photocatalyzed C-C-bond forming method for the benzylic C-H functionalization of phenolether containing synthetic building blocks based on a radical-cation/deprotonation strategy is reported. This method allows the mild, selective generation of benzyl radicals in phenolic complex molecules and drug-like compounds, providing new entries in synthetic and medicinal chemistry.

Organic/inorganic Fe3O4@MCM-41@Zr-piperazine: An impressive magnetite nanocatalyst for N-Tert-Butoxycarbonylation of amines

Fe3O4@MCM-41@Zirconium magnetic nanoparticles modified with piperazine (Fe3O4@MCM-41@Zr-piperazine), as a newly reported catalyst, shows excellent catalytic activity in N-tertbutoxycarbonylation of amines under the mild and solvent-free conditions. Accordingly, different derivatives of N-tert-butylcarbamates owning diverse aliphatic, aromatic and heteroaromatic amines were prepared efficiently. Good performance of this method for the majority of used complex or acidsensitive substrates and facile separation of this nanocatalyst due to its superparamagnetic nature from the reaction mixture via an external magnetic field for several times are the most important striking features of this protocol.

Direct C?H Phosphonylation of Electron-Rich Arenes and Heteroarenes by Visible-Light Photoredox Catalysis

The direct transformation of ubiquitous, but chemically inert C?H bonds into diverse functional groups is an important strategy in organic synthesis that improves the atom economy and faclitates the preparation and modification of complex molecules. In contrast to the wide applications of aryl phosphonates, their synthesis via direct C?H bond phosphonylation is a less explored area. We report here a general, mild, and broadly applicable visible-light photoredox C?H bond phosphonylation method for electron-rich arenes and heteroarenes. The photoredox catalytic protocol utilizes electron-rich arenes and biologically important heteroarenes as substrates, [Ru(bpz)3][PF6]2 as photocatalyst, ammonium persulfate as oxidant, and trialkyl phosphites as the phosphorus source to provide a wide range of aryl phosphonates at ambient temperature under very mild reaction conditions.