98098-19-2Relevant articles and documents
α-Sulfenylalkylation of carbonyl compounds at the α-position via magnesium amide-induced enamine sulfenylalkylation with sulfoxides
Kobayashi, Kazuhiro,Kawakita, Masataka,Irisawa, Susumu,Akamatsu, Hideki,Sakashita, Kouji,Morikawa, Osamu,Konishi, Hisatoshi
, p. 2691 - 2696 (2007/10/03)
The reactions of enamines with sulfoxides bearing α-hydrogens in the presence of a magnesium amide, generated in situ from the reaction of ethylmagnesium bromide with diisopropylamine, afforded the corresponding α-sulfenylalkylated ketones and aldehydes in isolated yields ranging from 39 to 76%. This procedure was successfully extended to the bis(methylthio)methylation with methyl (methylthio)methyl sulfoxide.
Regio- and chemoselective conjugate 1,4-reduction of α-oxoketene dithioacetals with sodium borohydride and sodium cyanoborohydride
Srinivasa Rao,Chakrasali,Ila, Hiriyakkanavar,Junjappa, Hiriyakkanavar
, p. 2195 - 2204 (2007/10/02)
Theα-oxoketene dithioacetals 1 are shown to undergo conjugate 1,4-reduction in highly regio- and chemoselective manner with sodium borohydride in acetic acid to afford the corresponding β-oxodithioacetals 5 in good yields. These results have been rational
