98266-32-1 Usage
Description
Boc-D-2-pyridylalanine, also known as (αR)-α-[[(1,1-Dimethylethoxy)carbonyl]amino]-2-pyridinepropanoic Acid, is a chiral amino acid derivative featuring a Boc-protected D-amino acid structure and a pyridine ring. This unique molecular configuration endows it with specific reactivity and selectivity in chemical synthesis and biological applications.
Uses
Used in Pharmaceutical Industry:
Boc-D-2-pyridylalanine is used as an intermediate in the synthesis of heterocyclic amides, which are designed to inhibit nitric oxide production. This application is particularly relevant for the development of drugs targeting conditions associated with excessive nitric oxide levels, such as inflammatory diseases and certain types of cancer.
Used in Chemical Synthesis:
In the field of chemical synthesis, Boc-D-2-pyridylalanine serves as a key building block for the creation of complex organic molecules with potential applications in various industries, including pharmaceuticals, agrochemicals, and materials science. Its Boc protection allows for selective deprotection and coupling reactions, facilitating the assembly of intricate molecular structures.
Used in Research and Development:
Boc-D-2-pyridylalanine is utilized in academic and industrial research settings to explore its properties and potential applications. Its unique structure makes it an interesting subject for studies on asymmetric synthesis, chiral recognition, and the development of novel catalysts and reagents.
Check Digit Verification of cas no
The CAS Registry Mumber 98266-32-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,8,2,6 and 6 respectively; the second part has 2 digits, 3 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 98266-32:
(7*9)+(6*8)+(5*2)+(4*6)+(3*6)+(2*3)+(1*2)=171
171 % 10 = 1
So 98266-32-1 is a valid CAS Registry Number.
InChI:InChI=1/C13H18N2O4/c1-13(2,3)19-12(18)15-10(11(16)17)8-9-6-4-5-7-14-9/h4-7,10H,8H2,1-3H3,(H,15,18)(H,16,17)/p-1/t10-/m1/s1
98266-32-1Relevant articles and documents
BICYCLIC COMPOUNDS
-
Paragraph 00375, (2020/10/28)
Provided herein are compounds and pharmaceutical compositions comprising said compounds that are useful for treating cancers. Specific cancers include those that are mediated by YAP/TAZ or those that are modulated by the interaction between YAP/TAZ and TEAD.
Studies on polypeptides XXXII. Solid-phase synthesis of RNase S-peptide 1-14 analogues; replacement of histidine-12 by β-(2-pyridyl)-L-alanine and β-(4-pyridyl)-L-alanine
Hoes, C.,Raap, J.,Bloemhoff, W.,Kerling, K. E. T.
, p. 99 - 104 (2007/10/02)
The synthesis of two analogues of the N-terminal tetradecapeptide of ribonuclease A (RNase S-peptide 1-14), in which the active site histidine-12 residue is replaced by β-(2-pyridyl)-L-alanine and β-(4-pyridyl)-L-alanine, has been accomplished by the solid-phase method.The enantiomers of β-(2-pyridyl)alanine were obtained by chymotryptic hydrolysis of its racemic Nα-acetyl ethyl ester.The Boc derivative of both L-amino acids has been synthesized.
