98277-30-6 Usage
Description
4,6-Dimethoxy-pyrazolo[3,4-d]pyrimidine is a chemical compound that serves as an intermediate in the synthesis of 4,6-Dihydroxypyrazolo[3,4-d]pyrimidine (D454550), which is a major metabolite of Allopurinol (A547300). Allopurinol is a well-known xanthine oxidase inhibitor, playing a crucial role in the treatment of hyperuricemia and gout.
Uses
Used in Pharmaceutical Industry:
4,6-Dimethoxy-pyrazolo[3,4-d]pyrimidine is used as a chemical intermediate for the synthesis of 4,6-Dihydroxypyrazolo[3,4-d]pyrimidine, which is a key metabolite of Allopurinol. This makes it an essential component in the development and production of medications aimed at treating hyperuricemia and gout, as well as potentially other conditions related to xanthine oxidase inhibition.
Check Digit Verification of cas no
The CAS Registry Mumber 98277-30-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,8,2,7 and 7 respectively; the second part has 2 digits, 3 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 98277-30:
(7*9)+(6*8)+(5*2)+(4*7)+(3*7)+(2*3)+(1*0)=176
176 % 10 = 6
So 98277-30-6 is a valid CAS Registry Number.
98277-30-6Relevant articles and documents
Chemo- and regioselective functionalization of uracil derivatives. Applications to the synthesis of oxypurinol and emivirine
Boudet, Nadege,Knochel, Paul
, p. 3737 - 3740 (2007/10/03)
A novel route for the synthesis of 4,5-difunctionalized uracils using a chemo- and regioselective bromine/magnesium exchange reaction on 5-bromo-4-halogeno-2,6-dimethoxypyrimidines has been developed. Applications to the synthesis of pharmaceuticals such as oxypurinol and emivirine are reported.