98421-02-4

Basic information

• Product Name: 6-anilino-2-thiouracil
• Synonyms: 6-anilino-2-thiouracil
• CAS NO: 98421-02-4
• Molecular Formula: C₁₀H₉N₃OS
• Molecular Weight: 0
• Mol File: 98421-02-4.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• Density: 1.4g/cm³
• Refractive Index: 1.712
• CAS DataBase Reference: 6-anilino-2-thiouracil(CAS DataBase Reference)
• NIST Chemistry Reference: 6-anilino-2-thiouracil(98421-02-4)
• EPA Substance Registry System: 6-anilino-2-thiouracil(98421-02-4)

Safety Data

• Hazardous Substances Data: 98421-02-4(Hazardous Substances Data)

Usage

InChI:InChI=1/C10H9N3OS/c14-9-6-8(12-10(15)13-9)11-7-4-2-1-3-5-7/h1-6H,(H3,11,12,13,14,15)

Upstream product

• 1004-40-6 6-Amino-2-thiouracil 
• 142-04-1 aniline hydrochloride 
• 62-53-3 aniline 

Downstream Products

• 407627-16-1 ethyl (1-phenyl-7-phenylamino-5-oxo-1,2,4-triazolo[4,3-a]pyrimidin-3-yl)carboxylate 
• 407627-38-7 1,2-dihydro-5-nitroso-6-(phenylamino)-2-thioxopyrimidin-4(3H)-one 
• 407627-18-3 ethyl (1-(p-chlorophenyl)-7-phenylamino-5-oxo-1,2,4-triazolo[4,3-a]pyrimidin-3-yl)carboxylate 
• 566163-94-8 methyl 5-oxo-1-phenyl-7-(phenylamino)-1,2,4-triazolo[4,3-a]pyrimidine-3-carboxylate 
• 120270-23-7 5-amino-6-anilino-1,2-dihydro-2-thioxopyrimidin-4(3H)-one 
• 1015763-70-8 6-anilino-2-methylthio-4-oxo-3,4-dihydropyrimidine 

Relevant articles and documents

Structural-based design, synthesis, and antitumor activity of novel alloxazine analogues with potential selective kinase inhibition

Protein kinases are promising therapeutic targets for cancer therapy. Here, we applied multiple approaches to optimize the potency and selectivity of our reported alloxazine scaffold. Flexible moieties at position 2 of the hetero-tricyclic system were inc

Pteridines. Part LXXXVII. Synthesis and Properties of 8-Substituted 2-Thiolumazines

Various 8-substituted 2,8-dihydro-2-thioxopteridin-4(3H)-ones (14-21) and 2-(methylthio)pteridin-4(8H)-ones (27-32) have been synthesized by condensation of the appropriate 5-amino-6-(substituted amino)-1,2-dihydro-2-thioxopyrimidin-4(3H)-ones (22-34) and 5-amino-6-(substituted amino)-2-(methylthio)pyrimidin-4(3H)-ones (25,26), respectively, with glyoxal, biacetyl, and benzil.The presence of a quinonoid cross-conjugated ?-electron system makes this type of compounds susceptible to nucleophilic additions in position 7, which laeds to intramolecular (43,45) and intermolecular (44) covalent adducts.The newly synthesized compounds have been characterized by elemental analyses, pKa determinations, 1H-NMR and UV spectra.UV-Spectral changes in dependence of the pH are associated with the most appropriate molecular species including the monocations, neutral forms, covalent adducts, mono- and dianions.