98464-65-4

Basic information

• Product Name: 5-(2-METHOXY-PHENYL)-3,4-DIHYDRO-2H-PYRROLE
• Synonyms: 5-(2-METHOXY-PHENYL)-3,4-DIHYDRO-2H-PYRROLE;3,4-dihydro-5-(2-methoxyphenyl)-2H-Pyrrole
• CAS NO: 98464-65-4
• Molecular Formula: C₁₁H₁₃NO
• Molecular Weight: 175.23
• Mol File: 98464-65-4.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 273.7°Cat760mmHg
• Flash Point: 98.9°C
• Appearance: /
• Density: 1.07g/cm³
• Vapor Pressure: 0.00944mmHg at 25°C
• Refractive Index: 1.556
• CAS DataBase Reference: 5-(2-METHOXY-PHENYL)-3,4-DIHYDRO-2H-PYRROLE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(2-METHOXY-PHENYL)-3,4-DIHYDRO-2H-PYRROLE(98464-65-4)
• EPA Substance Registry System: 5-(2-METHOXY-PHENYL)-3,4-DIHYDRO-2H-PYRROLE(98464-65-4)

Safety Data

• Hazardous Substances Data: 98464-65-4(Hazardous Substances Data)

Usage

InChI:InChI=1/C11H13NO/c1-13-11-7-3-2-5-9(11)10-6-4-8-12-10/h2-3,5,7H,4,6,8H2,1H3

Upstream product

• 14468-90-7 N-trimethylsilyl-pyrrolidin-2-one 
• 578-57-4 2-bromoanisole 
• 16750-63-3 2-methoxyphenylmagnesium bromide 
• 914954-39-5 tert-butyl [4-(2-methoxyphenyl)-4-oxobutyl]carbamate 
• 616-45-5 2-pyrrolidinon 

Downstream Products

• 1217612-37-7 (+)2-(2'-OMe-phenyl)-1-pyrrolidine 
• 1217612-37-7 (-)-2-(2'-OMe-phenyl)-1-pyrrolidine 
• 885044-30-4 (R)-2-(2-methoxyphenyl)pyrrolidine-1-carboxylic acid tert-butyl ester 
• 1314325-23-9 (S)-2-(2-methoxyphenyl)pyrrolidine-1-carboxylic acid tert-butyl ester 
• 103857-96-1 2-(2-methoxyphenyl)pyrrolidine 
• 1217612-37-7 (+)-2-(2-methoxyphenyl)pyrrolidine 
• 1217612-37-7 (S)-(–)-2-(2-methoxyphenyl)pyrrolidine 
• 1217612-37-7 (R)-(+)-2-(2-methoxyphenyl)pyrrolidine 

Relevant articles and documents

Synthesis of 1-Pyrroline by Denitrogenative Ring Expansion of Cyclobutyl Azides under Thermal Conditions

We herein report an efficient and systematic synthesis of 1-pyrrolines from cyclobutyl azides under thermal and neutral conditions. The reaction proceeded without any additional reagents, and nitrogen was generated as the sole by-product. Furthermore, the generated 1-pyrrolines could be continuously transformed into pyrroles, N-Boc-amines, and oxaziridines in an one-pot manner. (Figure presented.).

Enantioselective Imine Reduction Catalyzed by Phosphenium Ions

The first use of phosphenium cations in asymmetric catalysis is reported. A diazaphosphenium triflate, prepared in two or three steps on a multigram scale from commercially available materials, catalyzes the hydroboration or hydrosilylation of cyclic imin

AROMATIC HETEROCYCLIC DERIVATIVE AND PHARMACEUTICAL

The main purpose of the invention is to provide a novel aromatic heterocyclic derivative or a pharmaceutically acceptable salt thereof. Examples of the invention include aromatic heterocyclic derivatives represented by general formula [1] and pharmaceutically acceptable salts thereof. In formula [1], R1 represents phenyl optionally substituted with one or two groups selected from the group consisting of halogens ,as well as alkyls and alkoxys optionally substituted by halogens; R2 represents a hydrogen, an alkyl, cycloalkyl, or alkoxy optionally substituted by a halogen, or a heteroaryl optionally substituted by an alkyl; X represents CR3, and Y represents N or CR4, or X represents N, and Y represents CR4; and Z represents CR5 or N.