98534-83-9 Usage
Description
1-(4-METHOXYPHENYL)-5-(TRIFLUOROMETHYL)-1H-PYRAZOLE-4-CARBOXYLIC ACID is a chemical compound that belongs to the class of pyrazole derivatives. It is structurally composed of a pyrazole ring with a 4-methoxyphenyl group and a trifluoromethyl group attached at the 1 and 5 positions, respectively. 1-(4-METHOXYPHENYL)-5-(TRIFLUOROMETHYL)& has potential applications in the pharmaceutical industry, particularly in the development of new drugs with diverse pharmacological activities. Its unique chemical structure makes it a promising candidate for further research and development in the field of medicinal chemistry.
Uses
Used in Pharmaceutical Industry:
1-(4-METHOXYPHENYL)-5-(TRIFLUOROMETHYL)& is used as a chemical intermediate for the synthesis of various pharmaceutical compounds. Its unique structure allows for the development of drugs with novel mechanisms of action and potential therapeutic benefits.
Used in Medicinal Chemistry Research:
1-(4-METHOXYPHENYL)-5-(TRIFLUOROMETHYL)& is used as a key building block in the design and synthesis of new drug candidates. Its incorporation into drug molecules can lead to improved pharmacokinetic properties, such as enhanced solubility, bioavailability, and stability.
Used in Drug Discovery:
1-(4-METHOXYPHENYL)-5-(TRIFLUOROMETHYL)& is used as a starting material in the search for new therapeutic agents. Its chemical versatility enables the exploration of various structural modifications, which can result in the identification of promising drug candidates with improved efficacy and safety profiles.
Used in Drug Development:
1-(4-METHOXYPHENYL)-5-(TRIFLUOROMETHYL)& is used as a component in the formulation of new drugs. Its unique properties can contribute to the overall performance of the drug, such as enhancing target selectivity, reducing side effects, and prolonging the duration of action.
Check Digit Verification of cas no
The CAS Registry Mumber 98534-83-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,8,5,3 and 4 respectively; the second part has 2 digits, 8 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 98534-83:
(7*9)+(6*8)+(5*5)+(4*3)+(3*4)+(2*8)+(1*3)=179
179 % 10 = 9
So 98534-83-9 is a valid CAS Registry Number.
InChI:InChI=1/C12H9F3N2O3/c1-20-8-4-2-7(3-5-8)17-10(12(13,14)15)9(6-16-17)11(18)19/h2-6H,1H3,(H,18,19)
98534-83-9Relevant articles and documents
Discovery of Novel Inhibitors of Uridine Diphosphate- N-Acetylenolpyruvylglucosamine Reductase (MurB) from Pseudomonas aeruginosa, an Opportunistic Infectious Agent Causing Death in Cystic Fibrosis Patients
Abell, Chris,Blundell, Tom L.,Brown, Karen P.,Coyne, Anthony G.,Di Pietro, Ornella,Floto, R. Andres,Hess, Jeannine,Holland, Matthew T. O.,Kim, So Yeon,Marchetti, Chiara,Mendes, Vitor,Acebrón-García-De-Eulate, Marta,Mayol-Llinàs, Joan
, p. 2149 - 2173 (2022/02/14)
Pseudomonas aeruginosa is of major concern for cystic fibrosis patients where this infection can be fatal. With the emergence of drug-resistant strains, there is an urgent need to develop novel antibiotics against P. aeruginosa. MurB is a promising target
SPHINGOSINE-1-PHOSPHATE RECEPTOR AGONISTS
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Page/Page column 158, (2011/02/24)
Disclosed are compounds of Formula (I), or a stereoisomer or a pharmaceutically acceptable salt thereof, wherein: A is formula (II) Q is a substituted 5-membered monocyclic heteroaryl group; W is CH2, O, or NH; and R1, R2, R3, R4, R5, R6, m, n, t, and x are defined herein. Also disclosed are methods of using such compounds as selective agonists for G protein-coupled receptor S1P1, and pharmaceutical compositions comprising such compounds. These compounds are useful in treating, preventing, or slowing the progression of diseases or disorders in a variety of therapeutic areas, such as autoimmune diseases and vascular disease.