98537-45-2

Basic information

• Product Name: 4-bromo-2,5-dimethoxy-β-nitrostyrene
• Synonyms: 4-bromo-2,5-dimethoxy-β-nitrostyrene
• CAS NO: 98537-45-2
• Molecular Weight: 288.098
• Mol File: 98537-45-2.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 4-bromo-2,5-dimethoxy-β-nitrostyrene(CAS DataBase Reference)
• NIST Chemistry Reference: 4-bromo-2,5-dimethoxy-β-nitrostyrene(98537-45-2)
• EPA Substance Registry System: 4-bromo-2,5-dimethoxy-β-nitrostyrene(98537-45-2)

Safety Data

• Hazardous Substances Data: 98537-45-2(Hazardous Substances Data)

Upstream product

• 75-52-5 nitromethane 
• 31558-41-5 4-bromo-2,5-dimethoxybenzaldehyde 
• 25245-34-5 1-bromo-2,5-dimethoxybenzene 

Downstream Products

• 98537-46-3 2-methoxy-2-(4-bromo-2,5-dimethoxyphenyl)-1-nitroethane 
• 66142-81-2 2-(4-bromo-2,5-dimethoxyphenyl)-1-aminoethane 
• 1026511-90-9 2-(4-bromo-2,5-dimethoxyphenyl)-N-[(2-methoxyphenyl)methyl]ethanamine 

Relevant articles and documents

5-HT2A/5-HT2C Receptor Pharmacology and Intrinsic Clearance of N-Benzylphenethylamines Modified at the Primary Site of Metabolism

The toxic hallucinogen 25B-NBOMe is very rapidly degraded by human liver microsomes and has low oral bioavailability. Herein we report on the synthesis, microsomal stability, and 5-HT2A/5-HT2C receptor profile of novel analogues of 25B-NBOMe modified at the primary site of metabolism. Although microsomal stability could be increased while maintaining potent 5-HT2 receptor agonist properties, all analogues had an intrinsic clearance above 1.3 L/kg/h predictive of high first-pass metabolism.

Ring-substituted β-methoxyphenethylamines: A new class of psychotomimetic agents active in man

Four members of a new class of psychotomimetic agents have been synthesized and evaluated in man. These compounds, which incorporate a β-methoxy group onto a β-phenethylamine sidechain, are the first reported psychotomimetics which are structural analogues of the neurotransmitter noradrenaline. These substances are more potent than the corresponding phenethylamines (lacking a β-methoxy group) but less potent than the correspondingly substituted amphetamine derivatives.