98547-86-5

Basic information

• Product Name: 2-Pyridinecarboxylicacid,6-methyl-,hydrazide(9CI)
• Synonyms: 2-Pyridinecarboxylicacid,6-methyl-,hydrazide(9CI);6-methyl-2-Pyridinecarboxylic acid hydrazide
• CAS NO: 98547-86-5
• Molecular Formula: C₇H₉N₃O
• Molecular Weight: 151.17
• Product Categories: AMIDE
• Mol File: 98547-86-5.mol
• Article Data: 8

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-Pyridinecarboxylicacid,6-methyl-,hydrazide(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Pyridinecarboxylicacid,6-methyl-,hydrazide(9CI)(98547-86-5)
• EPA Substance Registry System: 2-Pyridinecarboxylicacid,6-methyl-,hydrazide(9CI)(98547-86-5)

Safety Data

• Hazardous Substances Data: 98547-86-5(Hazardous Substances Data)

Upstream product

• 39640-51-2 ethyl 6-methylpyridine-2-carboxylate 
• 13602-11-4 6-methylpicolinic acid methyl ester 
• 934-60-1 6-methyl-2-pyridinecarboxylic acid 

Downstream Products

• 109502-67-2 2,3-dimethoxy-6-[(6-methyl-pyridine-2-carbonylhydrazono)-methyl]-benzoic acid 
• 101281-48-5 6-methyl-pyridine-2-carboxylic acid-(4-acetylamino-benzylidenehydrazide) 
• 100867-62-7 6-methyl-pyridine-2-carboxylic acid benzylidenehydrazide 
• 1338374-99-4 [1,1'-biphenyl]-4-yl-(8-methyl-3-(6-methylpyridin-2-yl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)methanone 
• 1338372-26-1 (4-fluorophenyl)(3-(6-methylpyridin-2-yl)-5,6-dihydro-[1,2,4]-triazolo[4,3-a]pyrazin-7(8H)-yl)methanone 
• 1429557-57-2 (R)-(8-methyl-3-(6-methylpyridin-2-yl)-5,6-dihydro-[1,2,4]-triazolo[4,3-a]pyrazin-7(8H)-yl)(4-(thiophen-2-yl)phenyl)methanone 

Relevant articles and documents

Photo- and electro-luminescence of three TADF binuclear Cu(i) complexes with functional tetraimine ligands

Three new binuclear cuprous complexes with similar tetraimine ligands [Cu2(pytzph)(POP)2](BF4)2 (1), [Cu2(pytzphcf)(POP)2](BF4)2 (2) and [Cu2(pytzphcz)(POP)2](BF4)2 (3), (pytzph = 6,6′-(1-phenyl-1,2,4-triazole-3,5-diyl)bis(2-methylpyridine), pytzphcf = 6,6′-(1-(4-(trifluoromethyl)phenyl)-1,2,4-triazole-3,5-diyl)bis(2-methylpyridine), pytzphcz = 9-(4-(3,5-bis(6-methylpyridin-2-yl)-1,2,4-triazol-1-yl)phenyl)-carbazole and POP = bis[2-(diphenylphosphine)phenyl]ether), have been synthesized and characterized in order to compare the different effects of substituent groups on the photoluminescence (PL) and electroluminescence (EL) properties. These complexes exhibit highly efficient green thermally activated delayed fluorescence (TADF) with short decay times (5.5-16 μs) and high photoluminescence quantum yields (up to 79%) at room temperature in the solid form. These complexes have essentially identical emission energy. However, the influence of the substituents on the photoluminescence and electroluminescence efficiencies is evident. Complex 3 with the carbazole group shows the highest efficiency in terms of both PL and EL, exhibiting an EQE of 8.3%, a CE of 27.1 cd A-1 and a peak brightness of 2525 cd cm-2 in the solution-processed OLED, while complex 2 with a trifluoromethyl appendage exhibits poorer quantum efficiency than the others.

P2X7 MODULATORS

The present invention is directed to a compound of Formula (I): The invention also relates to pharmaceutical compositions comprising compounds of Formula (I). Methods of making and using the compounds of Formula (I) are also within the scope of the invent

NOVEL CHIRAL N-ACYL-5,6,7,(8-SUBSTITUTED)-TETRAHYDRO-[1,2,4]TRIAZOLO[4,3-a]PYRAZINES AS SELECTIVE NK-3 RECEPTOR ANTAGONISTS, PHARMACEUTICAL COMPOSITION, METHODS FOR USE IN NK-3 RECEPTOR MEDIATED DISORDERS AND CHIRAL SYNTHESIS THEREOF

The present invention relates to novel compounds of Formula I and their use in therapeutic treatments. The invention further relates to a novel chiral synthesis of 5,6,7,(8-substituted)-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazines using N-sp3 protective groups. The invention also provides intermediates for use in the synthesis of compounds of Formula I.