98648-23-8

Basic information

• Product Name: 4'-Nitro-[1,1'-biphenyl]-4-carboxaldehyde
• Synonyms: 4'-NITRO[1,1'-BIPHENYL]-4-CARBALDEHYDE;4'-Nitro-[1,1'-biphenyl]-4-carboxaldehyde;4-(4-Nitrophenyl)benzaldehyde;4-Formyl-4'-nitrobiphenyl, 4-(4-Nitrophenyl)benzaldehyde;4'-Nitrobiphenyl-4-carboxaldehyde
• CAS NO: 98648-23-8
• Molecular Formula: C₁₃H₉NO₃
• Molecular Weight: 227.22
• Mol File: 98648-23-8.mol
• Article Data: 4

Chemical Properties

• Melting Point: 117-120°C
• Boiling Point: 404.9 °C at 760 mmHg
• Flash Point: 200.6 °C
• Appearance: /
• Density: 1.274 g/cm³
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: 4'-Nitro-[1,1'-biphenyl]-4-carboxaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 4'-Nitro-[1,1'-biphenyl]-4-carboxaldehyde(98648-23-8)
• EPA Substance Registry System: 4'-Nitro-[1,1'-biphenyl]-4-carboxaldehyde(98648-23-8)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 98648-23-8(Hazardous Substances Data)

Usage

General Description

4'-Nitro-[1,1'-biphenyl]-4-carboxaldehyde is a chemical compound that belongs to the category of nitrobenzene. It is a yellow solid with the molecular formula C13H9NO3, and it is primarily used as an intermediate in chemical synthesis. 4'-Nitro-[1,1'-biphenyl]-4-carboxaldehyde is commonly found in various research and industrial applications, including pharmaceuticals, dyes, and pigments. It is also used in organic synthesis to introduce the 4'-nitro-[1,1'-biphenyl]-4-carboxaldehyde group into different molecules. However, it is important to handle this chemical with care, as it can be toxic, irritating to the skin, eyes, and respiratory system, and may cause allergic skin reactions.

Upstream product

• 2143-88-6 4-nitro-4'-methyl-1,1'-biphenyl 
• 87199-17-5 4-formylphenylboronic acid, 
• 100-00-5 4-chlorobenzonitrile 
• 4482-01-3 o-benzenedisulfonimide 
• 100-01-6 4-nitro-aniline 

Downstream Products

• 98629-81-3 5,5'-<4'-nitro-1,1'-biphenyl>-4-ylmethylenebis(6-methylaminouracil) 
• 98629-74-4 5,5'-<4'-nitro-1,1'-biphenyl>-4-ylmethylenebis(6-methylamino-3-methyluracil) 
• 98629-77-7 8-p-aminophenyl-3,10-dimethylpyrimido<4,5-b>quinoline-2,4(3H,10H)-dione 
• 98629-76-6 8-p-nitrophenyl-3,10-dimethylpyrimido<4,5-b>quinoline-2,4(3H,10H)-dione 
• 98629-78-8 8--3,10-dimethylpyrimido<4,5-b>quinoline-2,4(3H,10H)-dione 
• 1268280-19-8 2-(4'-nitrobiphenyl)-4,5-bis[4-(N,N-dimethylamino)phenyl]-1H-imidazole 
• 1380049-04-6 (S)-2-{(R)-hydroxy[4'-nitro-1,1'-biphenyl-4-yl]methyl}cyclopentanone 

Relevant articles and documents

Easily synthesizable benzothiazole based designers palladium complexes for catalysis of Suzuki coupling: Controlling effect of aryl substituent of ligand on role and composition of insitu generated binary nanomaterial (PdS or Pd16S7)

The present report is based on straightforward synthesis of molecular palladium complexes of benzothiazole based bulky ligands. Catalytic potential of 1[Pd(L1)2Cl2] and 2[Pd(L2)2Cl2] has been screened for Suzuki coupling. Due to structural difference between 1 and 2 (anthracen-9-yl in 1, and pyren-1-yl in 2), they behave as designers pre-catalysts and show different catalytic behaviour and nature by dispensing the nanoparticles of different materials (PdS by 1 and Pd16S7 by 2). This is an unprecedented observation as the size of the aryl substituent controls the efficiency (efficiency: 1 > 2) through determining the composition and nature of insitu generated nanoparticles.

Gold catalysed Suzuki-Miyaura coupling of arenediazonium o-benzenedisulfonimides

Arenediazonium o-benzenedisulfonimides have been used as efficient electrophilic partners in Au(I) catalysed Suzuki coupling reactions. The synthetic protocol is general, easy and produced either biaryls or heteroaryl arenes in good yields (51 positive examples, average yield 80%). o-Benzenedisulfonimide was recovered at the end of the reactions and was reused to prepare the starting salts for further reactions. Mechanistic insights suggest that the o-benzenedisulfonimide anion act as an electron transfer agent and promotes a catalytic cycle which does not require the presence of photocatalysts or external oxidants.