98657-84-2Relevant articles and documents
BASICITY AND STRUCTURE OF 5-HYDROXYBENZIMIDAZOLES IN NITROMETHANE
Korolev, B. A.,Osmolovskaya, L. A.,Kuznetsov, Yu. V.,Stolyarova, L. G.,Smirnov, L. D.
, p. 333 - 336 (2007/10/02)
Examination of the acid-base properties of 5-hydroxybenzimidazoles has shown them to exist in nitromethane as the 5-hydroxy-tautomers.Substituents in the 2-position have a predominantly inductive effect on the basicity of the 3-nitrogen, rationalized as in other nitrogen heterocycles by the proximity of the substituents to the reaction center. Keywords: 5-hydroxybenzimidazole, its tautomers and derivatives; acid-base properties and the effect thereon of substituents; Taft and inductive constants.
