98664-49-4

Basic information

• Product Name: 1-phenyl-3-trifluoromethylpyrazoline-cis-4,5-dicarboxylic acid
• CAS NO: 98664-49-4
• Molecular Weight: 302.21
• Mol File: 98664-49-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-phenyl-3-trifluoromethylpyrazoline-cis-4,5-dicarboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 1-phenyl-3-trifluoromethylpyrazoline-cis-4,5-dicarboxylic acid(98664-49-4)
• EPA Substance Registry System: 1-phenyl-3-trifluoromethylpyrazoline-cis-4,5-dicarboxylic acid(98664-49-4)

Safety Data

• Hazardous Substances Data: 98664-49-4(Hazardous Substances Data)

Upstream product

• 108-31-6 maleic anhydride 
• 86508-64-7 3-phenyl-5-trifluoromethyl-2,2,2-tris(4-methylphenoxy)-2,3-dihydro-1,3,4,2-oxadiazaphosphole 

Downstream Products

• 98664-43-8 trans-4,5-dimethoxycarbonyl-1-phenyl-3-trifluoromethyl-2-pyrazoline 

Relevant articles and documents

Cycloadditions of N-Aryl-C-(Trifluoromethyl)nitrilimines with Dimethyl Fumarate and Maleate

The cycloadditions of N-aryl-C-(trifluoromethyl)nitrilimines 1, generated in situ from various precursors, with dimethyl fumarate and maleate are described.N-Aryltrifluoroacetohydrazonoyl bromides 2 reacted with fumarate in the presence of triethylamine to give the trans-4,5-dimethoxycarbonylpyrazolines 4 whereas the reactions with maleate afforded the 4,5-dimethoxycarbonylpyrazoles 5 as well as 4.In the reactions with the chloride 6 under the more drastic conditions, both fumarate and maleate gave the pyrazole 5a.From thermolysis of the oxadiazaphosphole 8, thetrans-pyrazoline 4a was formed in both cases of fumarate and maleate.The preparation of the cis-pyrazoline 9 was attempted from 8 and maleic anhydride but 9 was found to be so unstable as to be epimerized under the mild conditions.