98674-96-5

Basic information

• Product Name: 1,2-bis(4-chlorophenyl) ethane-1,2-diaMine
• Synonyms: 1,2-Bis(4-chlorophenyl)-1,2-ethanediamine; 1,2-ethanediamine, 1,2-bis(4-chlorophenyl)-; (1R,2S)-1,2-bis(4-chlorophenyl)ethane-1,2-diaminium
• CAS NO: 98674-96-5
• Molecular Formula: C₁₄H₁₄Cl₂N₂
• Molecular Weight: 281.18036
• Mol File: 98674-96-5.mol
• Article Data: 12

Chemical Properties

• Boiling Point: 418.574°C at 760 mmHg
• Flash Point: 206.946°C
• Appearance: /
• Vapor Pressure: 0mmHg at 25°C
• CAS DataBase Reference: 1,2-bis(4-chlorophenyl) ethane-1,2-diaMine(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2-bis(4-chlorophenyl) ethane-1,2-diaMine(98674-96-5)
• EPA Substance Registry System: 1,2-bis(4-chlorophenyl) ethane-1,2-diaMine(98674-96-5)

Safety Data

• Hazardous Substances Data: 98674-96-5(Hazardous Substances Data)

Usage

General Description

1,2-bis(4-chlorophenyl)ethane-1,2-diamine, also known as dicofol, is a synthetic organochlorine compound that is used as an acaricide to control mites and ticks on crops. It is a white, crystalline solid with a faint odor, and it is insoluble in water but soluble in organic solvents. Dicofol has been banned in many countries due to its potential toxicity and persistence in the environment. It has been shown to be harmful to aquatic organisms and can bioaccumulate in food chains. Additionally, dicofol has been found to be a potential endocrine disruptor and a possible human carcinogen. Its production and use have been restricted and regulated in several countries to minimize its environmental and health impacts.

InChI:InChI=1/C14H14Cl2N2/c15-11-5-1-9(2-6-11)13(17)14(18)10-3-7-12(16)8-4-10/h1-8,13-14H,17-18H2/p+2/t13-,14+

Upstream product

• 115294-32-1 4-chloro-benzoic acid-[erythro-4,4'-dichloro-α'-(4-chloro-benzylidenamino)-bibenzyl-α-ylamide] 
• 41097-37-4 (1E, 2E)-1,2-bis (4-chlorobenzylidene) hydrazine 
• 3848-36-0 4-chlorobenzaldoxime 
• 104-88-1 4-chlorobenzaldehyde 
• 115294-32-1 C₂₈H₂₀Cl₄N₂O 

Downstream Products

• 86212-33-1 4,5-di(p-chlorophenyl)imidazoline-2-thione 
• 844692-35-9 trans-4,5-Bis-(4-chloro-phenyl)-2-(2-isopropoxy-4-methoxy-phenyl)-4,5-dihydro-1H-imidazole 
• 548785-15-5 2-(4-chloro-2-ethoxy-phenyl)-4,5-bis-(4-chloro-phenyl)-4,5-dihydro-1H-imidazole 
• 813463-21-7 4,5-bis-(4-chloro-phenyl)-2-(2-ethoxy-4-trifluoromethyl-phenyl)-4,5-dihydro-1H-imidazole 

Relevant articles and documents

MDM2 DEGRADERS AND USES THEREOF

The present invention relates to compounds and methods useful for the modulation of mouse double minute 2 homolog ("MDM2") protein via ubiquitination and/or degradation by compounds according to the present invention.

Chiral synthesis method for producing cis-imidazoline compounds for pharmaceutical use

This invention provides a method for enantioselective synthesis of cis-imidazolines and related structures through chiral resolution. A chiral acid is used to separate enantiomeric precursors of the cis-imidazolines from a racemic mixture by selective cry

Dimer ester micromolecule PROTACs for inducing MDM2 to self-degrade E3 ubiquitin ligase

The invention provides dimer ester micromolecule PROTACs for inducing MDM2 to self-degrade E3 ubiquitin ligase. The structure of the PROTACs is shown in the specification, wherein in a compound (I), L1 is C1-C30 linear or branched alkyl with or without a substituent group, and any carbon atom in L1 is optionally replaced by heteroatom; R1, R2, R3 and R4 are C1-C30 linear or branched alkyl with orwithout a substituent group, C1-C30 aryl with or a without substituent group, C1-C30 linear or branched alkylaryl with or without a substituent group or C1-C30 linear or branched aryl alkyl with or without a substituent group respectively and independently; X1, X2, X3 and X4 are halogen respectively and independently.