98829-12-0Relevant articles and documents
Selective etherification
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, (2008/06/13)
There is disclosed an improved process for substitution of the hydroxy group at 2-position of an ascorbic acid derivative according to the following reaction scheme: STR1 wherein R0 is hydrogen, alkyl having 1 to 6 carbon atoms, phenyl or a group of the formula STR2 (wherein X is two hydrogen atoms, or acetal or ketal residue); R1 is an alkyl or alkenyl group having up to 22 carbon atoms which may be substituted with phenyl or alkoxy having 1 to 22 carbon atoms; Y is halogen or optionally substituted sulfonyloxy; R is hydrogen, or primary, secondary or tertiary alkyl having 1 to 10 carbon atoms; and Z is an alkali metal or an alkali earth metal. There is also disclosed hydrolysis of the following scheme: STR3 wherein R1 is as defined above; and X is acetal or ketal residue.
Studies on scavengers of active oxygen species. 1. Synthesis and biological activity of 2-O-alkylascorbic acids
Kato,Terao,Shimamoto,Hirata
, p. 793 - 798 (2007/10/02)
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