98991-10-7Relevant articles and documents
Tuning Rate of the Bergman Cyclization of Benzannelated Enediynes with Ortho Substituents
Alabugin, Igor V.,Manoharan, Mariappan,Kovalenko, Serguei V.
, p. 1119 - 1122 (2002)
matrix presented The Bergman cyclization of benzannelated enediynes is highly sensitive to ortho substitution. This finding opens possibilities for the rational design of conformer-specific and pH-dependent DNA-cleaving agents.