99067-49-9

Basic information

• Product Name: 4(3H)-Quinazolinone,3-(chloromethyl)-(6CI)
• Synonyms: 4(3H)-Quinazolinone,3-(chloromethyl)-(6CI);4(3H)-Quinazolinone,3-(chloroMethyl)-;3-Chloromethyl-3H-quinazolin-4-one
• CAS NO: 99067-49-9
• Molecular Formula: C₉H₇ClN₂O
• Molecular Weight: 194.61768
• Product Categories: HALOMETYL
• Mol File: 99067-49-9.mol
• Article Data: 7

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4(3H)-Quinazolinone,3-(chloromethyl)-(6CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 4(3H)-Quinazolinone,3-(chloromethyl)-(6CI)(99067-49-9)
• EPA Substance Registry System: 4(3H)-Quinazolinone,3-(chloromethyl)-(6CI)(99067-49-9)

Safety Data

• Hazardous Substances Data: 99067-49-9(Hazardous Substances Data)

Usage

Description

4(3H)-Quinazolinone,3-(chloromethyl)-(6CI) is a chemical compound that belongs to the class of quinazolinone compounds. It is characterized by the presence of a quinazolinone core structure with a chloromethyl substituent at the 3-position. 4(3H)-Quinazolinone,3-(chloromethyl)-(6CI) has the potential to be used in pharmaceutical research and drug development due to its structural features and potential biological activities. The chloromethyl group can also serve as a versatile handle for further chemical modifications, making it a valuable building block for the synthesis of novel compounds with potential therapeutic applications. Additionally, the presence of the quinazolinone core structure suggests that this compound may possess interesting pharmacological properties, making it a promising candidate for further exploration in medicinal chemistry.

Uses

Used in Pharmaceutical Research and Drug Development:
4(3H)-Quinazolinone,3-(chloromethyl)-(6CI) is used as a building block for the synthesis of novel compounds with potential therapeutic applications. Its chloromethyl group serves as a versatile handle for further chemical modifications, allowing for the development of new drugs with improved efficacy and safety profiles.
Used in Medicinal Chemistry:
4(3H)-Quinazolinone,3-(chloromethyl)-(6CI) is used as a promising candidate for further exploration in medicinal chemistry due to its quinazolinone core structure, which may possess interesting pharmacological properties. 4(3H)-Quinazolinone,3-(chloromethyl)-(6CI) can be studied and modified to develop new drugs with potential applications in various therapeutic areas.
Used in Chemical Synthesis:
4(3H)-Quinazolinone,3-(chloromethyl)-(6CI) is used as a valuable building block in the synthesis of novel compounds with potential applications in various industries, including pharmaceuticals, agrochemicals, and materials science. Its unique structural features and reactivity make it a useful intermediate in the development of new chemical entities.

Upstream product

• 491-36-1 4-Hydroxyquinazoline 
• 50-00-0 formaldehyd 
• 14663-52-6 3-(hydroxymethyl)quinazolin-4(3H)-one 
• 118-92-3 anthranilic acid 

Relevant articles and documents

Synthesis and antibacterial evaluation of novel Schiff base derivatives containing 4(3H)-quinazolinone moiety

A series of novel Schiff base derivatives containing 4(3H)-quinazolinone moiety were synthesised and their antibacterial activities against tobacco and tomato bacterial wilts evaluated in vitro. Out of the synthesised compounds, 5g, 5j, 5n, 5m and 5p exhi

4(3H)-quinazolinone-containing 1,4-pentadiene-3-ketoxime ether derivatives and preparation method thereof

The invention discloses 4(3H)-quinazolinone-containing 1,4-pentadiene-3-ketoxime ether derivatives. The 4(3H)-quinazolinone-containing 1,4-pentadiene-3-ketoxime ether derivatives are characterized in that the general formula of the derivatives is described in the description, wherein R1 is phenyl, substituted phenyl or substituted aromatic heterocyclic group; R2 is phenyl, substituted phenyl or substituted aromatic heterocyclic group; R3 is one or more hydrogen atoms, methoxy group, nitro group, methyl group, trifluoromethyl group or halogen atoms contained in the 5, 6, 7 or 8 site of 4(3H)-quinazolinone. The compounds provided by the invention have higher treatment and protection functions for cucumber mosaic virus (CMV) and tobacco mosaic virus (TMV), and shows better plant virus resisting activity, thus being used for preparing anti-plant-virus pesticides.

[...] propoxycyclohexyl the pentadiene ketone compound, preparation method and application

The invention discloses a compound of resisting plant viruses: a pentadienone compound containing quinazolinone aryloxy and a preparation method and biological activity. The invention introduces a series of novel pentadienone derivatives containing quinazolinone aryloxy which are synthesized by six steps by taking substituted o-aminobenzoic acid, formamide, 35% formalin, 1, 4-dioxane, thionyl chloride, hydroxyl benzaldehyde, acetone, sodium hydroxide, hydrochloric acid, potassium carbonate, potassium iodide, substituted aromatic aldehyde, substituted heterocyclic aldehyde and the like as raw materials. The compound disclosed by the invention further has higher treating, protecting and passivating and inhibiting effects to cucumber mosaic virus (CMV), tobacco mosaic virus (TMV), southern rice black streaked dwarf virus (SRBSDV) and rice stripe virus (RSV), shows higher anti-plant virus activity, and can be used for preparing anti-plant virus pesticides.