99113-28-7Relevant articles and documents
Synthesis and biological evaluations of novel endomorphin analogues containing α-hydroxy-β-phenylalanine (AHPBA) displaying mixed μ/δ opioid receptor agonist and δ opioid receptor antagonist activities
Hu, Miao,Giulianotti, Marc A.,McLaughlin, Jay P.,Shao, Jiaan,Debevec, Ginamarie,Maida, Laura E.,Geer, Phaedra,Cazares, Margaret,Misler, Jaime,Li, Ling,Dooley, Colette,Ganno, Michelle L.,Eans, Shainnel O.,Mizrachi, Elisa,Santos, Radleigh G.,Yongye, Austin B.,Houghten, Richard A.,Yu, Yongping
, p. 270 - 281 (2015/04/21)
A novel series of endomorphin-1 (EM-1) and endomorphin-2 (EM-2) analogues was synthesized, incorporating chiral α-hydroxy-β-phenylalanine (AHPBA), and/or Dmt1-Tic2 at different positions. Pharmacological activity and metabolic stabil
Enantiospecific formation of 3,6-dihydro-1H-pyridin-2-ones: Low-pressure palladium-catalysed decarboxylative carbonylation of 3-tosyl-5-vinyloxazolidin- 2-ones
Knight, Julian G.,Lawson, Iain M.,Johnson, Christopher N.
, p. 227 - 230 (2007/10/03)
Palladium-catalysed decarboxylative carbonylation of 3-tosyl-5- vinyloxazolidin-2-ones 5 occurs at atmospheric pressure to give 1-tosyl-3,6-dihydro-1H-pyridin-2-ones 6. The reaction proceeds with no loss of enantiopurity and detosylation with sodium napht
A stereocontrolled synthesis of hapalosin
Oshitari, Tetsuta,Saiyinbilige,Mandai, Tadakatsu
, p. 185 - 190 (2007/10/03)
A facile synthetic method for two components of hapalosin, that is, β-hydroxy-γ-amino acid and β-hydroxy acid, has been established by utilizing chiral building blocks efficiently resolved in a lipase-catalyzed transesterification. Furthermore, the synthe