992-36-9

Basic information

• Product Name: 1H-Pyrrole-3-propanoic acid, 2,2'-methylenebis[4-methyl-5-[(phenylmethoxy)carbonyl]-, dimethyl ester
• CAS NO: 992-36-9
• Molecular Formula: C35H38N2O8
• Molecular Weight: 614.695
• Mol File: 992-36-9.mol
• Article Data: 17

Chemical Properties

• CAS DataBase Reference: 1H-Pyrrole-3-propanoic acid, 2,2'-methylenebis[4-methyl-5-[(phenylmethoxy)carbonyl]-, dimethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Pyrrole-3-propanoic acid, 2,2'-methylenebis[4-methyl-5-[(phenylmethoxy)carbonyl]-, dimethyl ester(992-36-9)
• EPA Substance Registry System: 1H-Pyrrole-3-propanoic acid, 2,2'-methylenebis[4-methyl-5-[(phenylmethoxy)carbonyl]-, dimethyl ester(992-36-9)

Safety Data

• Hazardous Substances Data: 992-36-9(Hazardous Substances Data)

Usage

Chemical class

Potent synthetic cannabinoid

Explanation

MDMB-CHMICA is a man-made compound that mimics the effects of natural cannabinoids like THC.

Explanation

It is created and sold illicitly for recreational use, often to bypass drug laws that target known substances.

Explanation

It belongs to a specific class of cannabinoids that have a carboxamide functional group.

Explanation

MDMB-CHMICA is derived from the indole chemical structure, which is a core structure found in many natural and synthetic cannabinoids.

Explanation

These are the primary effects experienced by users, which contribute to its popularity as a recreational drug.

Explanation

MDMB-CHMICA can have serious negative consequences for users, including the potential for abuse and life-threatening complications.

Explanation

Due to its risks and potential for abuse, MDMB-CHMICA is regulated and restricted in numerous countries, making it illegal to manufacture, distribute, or possess for recreational use.

Designer drug

Yes

Carboxamide class of cannabinoids

Member

Indole class derivative

Yes

Psychoactive effects

Euphoria, relaxation, altered perception of time and space, hallucinations

Health risks

Addiction, respiratory depression, potential overdose

Legal status

Controlled substance in many countries

Upstream product

• 859-38-1 benzyl 5-acetoxymethyl-4-(2-methoxycarbonylethyl)-3-methylpyrrole-2-carboxylate 
• 60204-90-2 5-dimethylamido-4-(2'-methoxycarbonylethyl)-3-methylpyrrole 
• 50622-67-8 5-acetoxymethyl-3-(2-methoxycarbonyl-ethyl)-4-methoxycarbonylmethyl-pyrrole-2-carboxylic acid benzyl ester 
• 20303-31-5 benzyl 4-(2-methoxycarbonylethyl)-3,5-dimethylpyrrole-2-carboxylate 
• 27331-98-2 benzyl (Z/E)-2-hydroxyimino-3-oxobutanoate 
• 5396-89-4 benzyl acetoacetate 
• 123-54-6 acetylacetone 
• 111017-83-5 ethyl 3-(2-ethoxycarbonylethyl)-4-methoxycarbonylmethyl-5-methylpyrrole-2-carboxylate 
• 111017-82-4 ethyl 5-methoxycarbonylmethyl-4,6-dioxoheptanoate 
• 50622-64-5 benzyl 3-(2-methoxycarbonylethyl)-4-methoxycarbonylmethyl-5-methylpyrrole-2-carboxylate 
• 31896-84-1 5-chlorocarbonyl-4-(2-methoxycarbonyl-ethyl)-3-methyl-pyrrole-2-carboxylic acid benzyl ester 
• 74839-00-2 methyl 5-methyl-4,6-dioxoheptanoate 
• 60205-10-9 3-(2-dimethylcarbamoyl-5-iodo-4-methyl-pyrrol-3-yl)-propionic acid methyl ester 
• 37538-30-0 5-dimethylcarbamoyl-4-(2-methoxycarbonyl-ethyl)-3-methyl-pyrrole-2-carboxylic acid benzyl ester 

Downstream Products

• 26019-77-2 dibenzyl 3,7-Bis(2-methoxycarbonylethyl)-2,8-dimethyldipyrroketone-1,9-dicarboxylate 
• 256638-30-9 3-{5-[3-(1-benzyloxy-ethyl)-4-methyl-5-oxo-pyrrolidin-2-ylidenemethyl]-2-[3-(2-methoxycarbonyl-ethyl)-4-methyl-5-(3-methyl-5-oxo-4-vinyl-5H-furan-2-ylidenemethyl)-pyrrol-2-ylidenemethyl]-4-methyl-1H-pyrrol-3-yl}-propionic acid methyl ester 
• 256638-29-6 3-{5-[3-(1-benzyloxy-ethyl)-4-methyl-5-oxo-dihydro-furan-2-ylidenemethyl]-2-[3-(2-methoxycarbonyl-ethyl)-4-methyl-5-(3-methyl-5-oxo-4-vinyl-5H-furan-2-ylidenemethyl)-pyrrol-2-ylidenemethyl]-4-methyl-1H-pyrrol-3-yl}-propionic acid methyl ester 
• 256638-23-0 3-{5-[(Z)-4-Carbamoyl-6-(4-chloro-phenylselanyl)-3-methyl-hex-3-en-1-ynyl]-2-[1-[5-iodo-3-(2-methoxycarbonyl-ethyl)-4-methyl-1H-pyrrol-2-yl]-meth-(Z)-ylidene]-4-methyl-2H-pyrrol-3-yl}-propionic acid methyl ester 

Relevant articles and documents

Alternate syntheses of pyrromethanes and porphyrins using acid-modified montmorillonite K-10 clay

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Catalytic hydrogenation of dibenzyl 5-dipyrroketone-2,9-dicarboxylates followed by decarboxylative iodination affords a 2,9-diiododipyrroketone which gives a 2,5,9-trichlorodipyrromethene hydrochloride after nucleophilic addition/elimination, with adventitious chloride to replace the two iodide groups. Treatment with BF3·Et2O gives a 3,5,8-trichloro-BODIPY that readily undergoes regioselective Stille coupling at the 8-position, or homo/mixed couplings at the 3,8- or 3,5- and 8-positions. Stepwise and controlled replacement of the 3,5- and 8-chlorine atoms using Stille reagents results in formation of a completely unsymmetrical trisubstituted BODIPY. Several examples of unsymmetrical BODIPYs were synthesized and characterized using this methodology. Structure features of new BODIPYs are discussed within the context of 14 new X-ray structures, and photophysical parameters of all new BODIPY compounds are reported and discussed.

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