99215-51-7

Basic information

• Product Name: Ethanone, 1-[4-(2-hydroxyethyl)phenyl]-
• CAS NO: 99215-51-7
• Molecular Formula: C10H12O2
• Molecular Weight: 164.204
• Mol File: 99215-51-7.mol
• Article Data: 10

Chemical Properties

• CAS DataBase Reference: Ethanone, 1-[4-(2-hydroxyethyl)phenyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanone, 1-[4-(2-hydroxyethyl)phenyl]-(99215-51-7)
• EPA Substance Registry System: Ethanone, 1-[4-(2-hydroxyethyl)phenyl]-(99215-51-7)

Safety Data

• Hazardous Substances Data: 99215-51-7(Hazardous Substances Data)

Upstream product

• 102494-22-4 1-[4-(2-hydroxyethyl)phenyl]ethanone oxime 
• 103-45-7 acetic acid phenethyl ester 
• 60-12-8 2-phenylethanol 
• 75-36-5 acetyl chloride 
• 94771-82-1 1-[4-(2-Hydroxy-ethyl)-phenyl]-ethanol 
• 102494-24-6 1-<4-(2-hydroxyethyl)phenyl>ethanone (2,4-dinitrophenyl)hydrazone 
• 73823-79-7 β-(4-acetylphenyl)ethyl acetate 

Downstream Products

• 93205-89-1 4-methoxyethylacetophenone 
• 99215-52-8 4-ethoxyethylacetophenone 
• 1237521-85-5 C₁₁H₁₃ClO₂ 
• 102494-22-4 1-[4-(2-hydroxyethyl)phenyl]ethanone oxime 
• 82099-82-9 Acetic acid 4-(2-methoxy-ethyl)-phenyl ester 
• 88318-14-3 4-(2-ethoxyethyl)phenol 
• 56718-71-9 4-(2-methoxyethyl)phenol 

Relevant articles and documents

Chemoselective Cleavage of Si-C(sp3) Bonds in Unactivated Tetraalkylsilanes Using Iodine Tris(trifluoroacetate)

Organosilanes are synthetically useful reagents and precursors in organic chemistry. However, the typical inertness of unactivated Si-C(sp3) bonds under conventional reaction conditions has hampered the application of simple tetraalkylsilanes in organic synthesis. Herein we report the chemoselective cleavage of Si-C(sp3) bonds of unactivated tetraalkylsilanes using iodine tris(trifluoroacetate). The reaction proceeds smoothly under mild conditions (-50 °C to room temperature) and tolerates various polar functional groups, thus enabling subsequent Tamao-Fleming oxidation to provide the corresponding alcohols. NMR experiments and density functional theory calculations on the reaction indicate that the transfer of alkyl groups from Si to the I(III) center and the formation of the Si-O bond proceed concertedly to afford an alkyl-λ3-iodane and silyl trifluoroacetate. The developed method enables the use of unactivated tetraalkylsilanes as highly stable synthetic precursors.

AMINE COMPOUND AND PHARMACEUTICAL USE THEREOF

Provided is a novel amine compound represented by the following formula (I) having a superior peripheral blood lymphocyte decreasing action and superior in the immunosuppressive action, rejection suppressive action and the like, which shows decreased side effects of, for example, bradycardia and the like, or a pharmaceutically acceptable acid addition salt thereof, or a hydrate thereof, or a solvate thereof. wherein each symbol is as defined in the specification.

Oxidation of benzylic alcohols to carbonyl compounds with potassium permanganate in ionic liquids

The selective oxidation of primary and secondary benzylic alcohols with potassium permanganate in ionic liquids to give corresponding aldehydes and ketones in 83-97% yields has been described.