99277-72-2

Basic information

• Product Name: diethyl 2-(4-bromo-2-nitrobenzoyl)malonate
• Synonyms: diethyl 2-(4-bromo-2-nitrobenzoyl)malonate
• CAS NO: 99277-72-2
• Molecular Weight: 388.172
• Mol File: 99277-72-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: diethyl 2-(4-bromo-2-nitrobenzoyl)malonate(CAS DataBase Reference)
• NIST Chemistry Reference: diethyl 2-(4-bromo-2-nitrobenzoyl)malonate(99277-72-2)
• EPA Substance Registry System: diethyl 2-(4-bromo-2-nitrobenzoyl)malonate(99277-72-2)

Safety Data

• Hazardous Substances Data: 99277-72-2(Hazardous Substances Data)

Upstream product

• 99277-71-1 4-bromo-2-nitrobenzoic acid 
• 112734-21-1 4-bromo-2-nitro-benzoyl chloride 
• 105-53-3 diethyl malonate 

Downstream Products

• 90004-94-7 4’-bromo-2’-nitroacetophenone 

Relevant articles and documents

PRMT5 INHIBITORS

The present invention provides a compound of Formula (I) and the pharmaceutically acceptable salts, esters, and prodrugs thereof, which are PRMT5 inhibitors. Also provided are methods of making compounds of Formula I, pharmaceutical compositions comprising compounds of Formula I, and methods of using these compounds to treat cancer, sickle cell, and hereditary persistence of foetal hemoglobin (HPFH) mutations.