99365-63-6

Basic information

• Product Name: 1-(3,4-dihydro-7-nitro-2(1H)-isoquinolinyl)ethanone
• Synonyms: 1-(3,4-dihydro-7-nitro-2(1H)-isoquinolinyl)ethanone
• CAS NO: 99365-63-6
• Molecular Weight: 220.228
• Mol File: 99365-63-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-(3,4-dihydro-7-nitro-2(1H)-isoquinolinyl)ethanone(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(3,4-dihydro-7-nitro-2(1H)-isoquinolinyl)ethanone(99365-63-6)
• EPA Substance Registry System: 1-(3,4-dihydro-7-nitro-2(1H)-isoquinolinyl)ethanone(99365-63-6)

Safety Data

• Hazardous Substances Data: 99365-63-6(Hazardous Substances Data)

Usage

General Description

1-(3,4-dihydro-7-nitro-2(1H)-isoquinolinyl)ethanone, also known as SMT-110 is a synthetic compound with a molecular formula C11H10N2O3. It belongs to the class of nitroisoquinolines and is used as a research chemical. 1-(3,4-dihydro-7-nitro-2(1H)-isoquinolinyl)ethanone has been studied for its potential as a therapeutic agent in the treatment of various neurological disorders, including Parkinson's disease and other neurodegenerative conditions. It is a potent inhibitor of monoamine oxidase B (MAO-B), an enzyme involved in the metabolism of dopamine and other neurotransmitters in the brain. Additionally, it has shown anti-inflammatory and antioxidant properties, making it a promising candidate for further pharmacological research and drug development.

Upstream product

• 50-00-0 formaldehyd 
• 6270-07-1 N-<2-(4-nitrophenyl)ethyl>acetamide 

Downstream Products

• 13058-73-6 7-nitroisoquinoline 
• 174648-93-2 N-acetyl-7-amino-6-nitro-1,2,3,4-tetrahydroisoquinoline 
• 186390-77-2 6-nitro-1,2,3,4-tetrahydro-isoquinoline 
• 791040-11-4 8-nitro-1,2,3,4-tetrahydroisoquinoline 
• 81885-67-8 2-acetyl-7-amino-1,2,3,4-tetrahydro-isoquinoline 
• 42923-79-5 7-nitro-1,2,3,4-tetrahydroisoquinoline 

Relevant articles and documents

PYRAZOLOPYRIMIDINE DERIVATIVES, PREPARATION METHOD THEREOF, AND PHARMACEUTICAL COMPOSITION FOR USE IN PREVENTING OR TREATING CANCER, AUTOIMMUNE DISEASE AND BRAIN DISEASE CONTAINING THE SAME AS AN ACTIVE INGREDIENT

The present invention relates to a pyrazolopyrimidine derivative, a preparation method thereof and a pharmaceutical composition comprising the same as an active ingredient for the prevention or treatment of cancer, autoimmune disease and brain disease. The pyrazolopyrimidine derivative of the present invention exhibits excellent Bruton's tyrosine kinase inhibition activity, so that it can be effectively used as a pharmaceutical composition for the prevention or treatment of cancer, autoimmune disease and Parkinson's disease.