99423-50-4

Basic information

• Product Name: ethyl-3-benzyl-2-oxo-cyclohexanecarboxylate
• Synonyms: ethyl-3-benzyl-2-oxo-cyclohexanecarboxylate
• CAS NO: 99423-50-4
• Molecular Weight: 260.333
• Mol File: 99423-50-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: ethyl-3-benzyl-2-oxo-cyclohexanecarboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl-3-benzyl-2-oxo-cyclohexanecarboxylate(99423-50-4)
• EPA Substance Registry System: ethyl-3-benzyl-2-oxo-cyclohexanecarboxylate(99423-50-4)

Safety Data

• Hazardous Substances Data: 99423-50-4(Hazardous Substances Data)

Upstream product

• 100-39-0 benzyl bromide 
• 1655-07-8 ethyl 2-oxocyclohexane carboxylate 
• 946-33-8 2-benzylcyclohexan-1-one 
• 95-92-1 oxalic acid diethyl ester 

Relevant articles and documents

Dynamic Kinetic Resolution of I-Substituted Cyclic β-Ketoesters via Asymmetric Hydrogenation: Constructing Chiral Cyclic β-Hydroxyesters with Three Contiguous Stereocenters

An efficient asymmetric hydrogenation of racemic I-substituted cyclic β-ketoesters via dynamic kinetic resolution to provide chiral cyclic β-hydroxy esters with three contiguous stereocenters is reported. Using a chiral spiro iridium catalyst (R)-5 (Ir-SpiroSAP), a series of racemic I-Aryl/alkyl substituted cyclic β-ketoesters were hydrogenated to the corresponding chiral cyclic β-hydroxy esters in high yields (84-97%) with good to excellent enantioselectivities (69->99% ee) and cis,cis-selectivities (up to >99:1).