99433-28-0

Basic information

• Product Name: 2-BROMO-1-(4-CYCLOHEXYLPHENYL)ETHANONE
• Synonyms: 2-BROMO-1-(4-CYCLOHEXYLPHENYL)ETHANONE;2-BroMo-4'-cyclohexylacetophenone;2-broMo-1-(4-cyclohexylphenyl)ethan-1-one
• CAS NO: 99433-28-0
• Molecular Formula: C₁₄H₁₇BrO
• Molecular Weight: 281.19
• Mol File: 99433-28-0.mol
• Article Data: 16

Chemical Properties

• Boiling Point: 368°Cat760mmHg
• Flash Point: 53.1°C
• Appearance: /
• Density: 1.305g/cm³
• CAS DataBase Reference: 2-BROMO-1-(4-CYCLOHEXYLPHENYL)ETHANONE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-BROMO-1-(4-CYCLOHEXYLPHENYL)ETHANONE(99433-28-0)
• EPA Substance Registry System: 2-BROMO-1-(4-CYCLOHEXYLPHENYL)ETHANONE(99433-28-0)

Safety Data

• Hazardous Substances Data: 99433-28-0(Hazardous Substances Data)

Usage

General Description

2-BROMO-1-(4-CYCLOHEXYLPHENYL)ETHANONE is a chemical compound with the molecular formula C15H19BrO. It is a white to off-white solid that is commonly used in the synthesis of various organic compounds. It is known for its strong odor and is often used as a flavoring agent in the food and beverage industry. It is also used as a reagent in organic synthesis, particularly in the production of pharmaceuticals and agrochemicals. Additionally, it has been studied for its potential biological activities, including antimicrobial and anti-inflammatory properties. Overall, 2-BROMO-1-(4-CYCLOHEXYLPHENYL)ETHANONE is a versatile chemical compound with various industrial and research applications.

Upstream product

• 827-52-1 1-phenyl-1-cyclohexane 
• 598-21-0 2-Bromoacetyl bromide 
• 18594-05-3 4-cyclohexylacetophenone 
• 37592-72-6 1-(4-hexyl-phenyl)-ethanone 

Downstream Products

• 102012-13-5 2-(4-cyclohexyl-phenyl)-indolizine 
• 102663-18-3 6-ethyl-2-(4-cyclohexyl-phenyl)-indolizine 
• 114507-77-6 2-(4-cyclohexyl-phenyl)-7-methyl-indolizine 
• 114493-29-7 2-(4-cyclohexyl-phenyl)-6-methyl-indolizine 
• 102316-41-6 2-(4-cyclohexyl-phenyl)-quinoxaline 
• 180901-43-3 6-chloro-2-(4'-cyclohexylphenyl)imidazo<1,2-b>pyridazine 
• 93078-50-3 3-(4-Chloro-benzoyl)-1-(4-cyclohexyl-phenyl)-pentane-1,4-dione 
• 3488-45-7 2-<4-Cyclohexyl-phenyl>-2-oxo-diazoaethan 
• 188692-52-6 2-(4-Cyclohexyl-phenyl)-6-iodo-imidazo[1,2-b]pyridazine 
• 192312-40-6 benzofuran-2-yl-(4-cyclohexyl-phenyl)-methanone 
• 332045-62-2 2-[4-(4-cyclohexyl-phenyl)-thiazol-2-yl]-3-(3-phenoxy-phenyl)-acrylonitrile 
• 887908-74-9 benzofuran-2-yl-(4-cyclohexyl-phenyl)-methanol 
• 102316-45-0 2-(4-cyclohexyl-phenyl)-3-nitroso-indolizine 

Relevant articles and documents

Reactivity of substrates with multiple competitive reactive sites toward NBS under neat reaction conditions promoted by visible light

Regioselectivity of visible-light-induced transformations of a range of (hetero)aryl alkyl-substituted ketones bearing several competitive reactive sites (α-carbonyl, benzyl and aromatic ring) with N-bromosuccinimide (NBS) was studied under solvent-free reaction conditions (SFRC) and in the absence of inert-gas atmosphere, radical initiators and catalysts. An 8-W energy-saving household lamp was used for irradiation. Heterogeneous reaction conditions were dealt with throughout the study. All substrates were mono- or dibrominated at the α-carbonyl position, and additionally, some benzylic or aromatic bromination was observed in substrates with benzylic carbon atoms or electron-donating methoxy groups, respectively. Surprisingly, ipso-substitution of the acyl group with a bromine atom took place with (4-methoxynaphthyl) alkyl ketones. While the addition of the radical scavenger TEMPO (2,2,6,6-tetramethylpiperidin-1-yloxy) decreased the extent of α- and ring bromination, it completely suppressed the benzylic bromination and α,α-dibromination with NBS under SFRC.

Discovery of novel potent GPR40 agonists containing imidazo[1,2-a]pyridine core as antidiabetic agents

Free fatty acid receptor 1 (FFA1 or GPR40) has been studied for many years as a target for the treatment of type 2 diabetes mellitus. In order to increase potency and reduce hepatotoxicity, a series of novel compounds containing imidazo[1,2-a]pyridine sca

2-AMINO-1,3,4-THIADIAZINE AND 2-AMINO-1,3,4-OXADIAZINE BASED ANTIFUNGAL AGENTS

The invention provides a compound which is a diazine of formula (I) or a tautomer thereof, or a pharmaceutically acceptable salt thereof, for use as an antifungal agent: (I) wherein X, N', C', A and E are as defined herein. The invention also provides a compound of Formula (I) as defined herein.