99439-78-8

Basic information

• Product Name: (S)-(+)-2-phenylhexane
• Synonyms: (S)-(+)-2-phenylhexane
• CAS NO: 99439-78-8
• Molecular Weight: 162.275
• Mol File: 99439-78-8.mol
• Article Data: 15

Chemical Properties

• CAS DataBase Reference: (S)-(+)-2-phenylhexane(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-(+)-2-phenylhexane(99439-78-8)
• EPA Substance Registry System: (S)-(+)-2-phenylhexane(99439-78-8)

Safety Data

• Hazardous Substances Data: 99439-78-8(Hazardous Substances Data)

Upstream product

• 20826-80-6 2-phenylhex-1-ene 
• 22800-20-0 (-)-R-5-Phenylhexansaeure 
• 36617-83-1 (-)-R-N,N-Dimethyl-5-phenylhexanamid 
• 36617-86-4 (-)-R-N,N-Dimethyl-5-phenylhexylamin 
• 27798-98-7 (-)(R)-4-bromo-2-phenyl-butane 
• 2031-46-1 (R)-3-phenylbutanol 
• 772-14-5 (R)-3-phenylbutyric acid 
• 36617-92-2 (-)-R-5-Phenyl-1-hexen 
• 28591-23-3 (+)(S)-6-bromo-2-phenyl-hexane 

Downstream Products

• 66553-51-3 (-)(S)-2-cyclohexyl-hexane 

Relevant articles and documents

Synthesis of enantiomerically pure allenes with central and axial chirality mediated by a remote sulfinyl group

Enantiomerically pure 2-(p-tolylsulfinyl)benzylcopper reagents react with propargyl bromides and mesylates, affording enantiomerically pure allenes with central and axial chirality. Both regioselectivity (SN2 processes) and configuration at the

Tandem Peterson olefination and chemoselective asymmetric hydrogenation of β-hydroxy silanes

Here, we report the first Ir-N,P complex catalyzed tandem Peterson olefination and asymmetric hydrogenation of β-hydroxy silanes. This reaction resulted in the formation of chiral alkanes in high isolated yields (up to 99%) and excellent enantioselectivity (up to 99% ee) under mild conditions. Modification of the reaction conditions provides a choice to transform either an olefin or the β-hydroxy silane in a chemoselective manner. Additionally, based on this method, an expedient enantioselective synthesis of (S)-(+)-α-curcumene, from a simple ketone, was accomplished in two steps with 75% overall yield and 95% ee.

Extending the substrate scope of bicyclic p-oxazoline/thiazole ligands for ir-catalyzed hydrogenation of unfunctionalized olefins by introducing a biaryl phosphoroamidite group

This study identifies a series of Ir-bicyclic phosphoroamidite-oxazoline/thiazole catalytic systems that can hydrogenate a wide range of minimally functionalized olefins (including E- and Z-tri- and disubstituted substrates, vinylsilanes, enol phosphinates, tri- and disubstituted alkenylboronic esters, and ?±,?2-unsaturated enones) in high enantioselectivities (ee values up to 99%) and conversions. The design of the new phosphoroamidite-oxazoline/thiazole ligands derives from a previous successful generation of bicyclic N-phosphane-oxazoline/thiazole ligands, by replacing the N-phosphane group with a p-acceptor biaryl phosphoroamidite moiety. A small but structurally important family of Ir-phosphoroamidite-oxazoline/thiazole precatalysts has thus been synthesized by changing the nature of the Ndonor group (either oxazoline or thiazole) and the configuration at the biaryl phosphoroamidite moiety. The substitution of the N-phosphane by a phosphoroamidite group in the bicyclic N-phosphane-oxazoline/thiazole ligands extended the range of olefins that can be successfully hydrogenated.