99439-79-9Relevant articles and documents
Stereospecific inversion of secondary tosylates to yield chiral methyl-branched building blocks, applied to the asymmetric synthesis of leafminer sex pheromones
Taguri, Tomonori,Yamakawa, Rei,Fujii, Toru,Muraki, Yuta,Ando, Tetsu
, p. 852 - 858 (2012/09/22)
All four of the possible stereoisomers of 5,9-dimethylheptadecane, the major sex pheromone component secreted by female moths of the mountain-ash bentwing (Leucoptera scitella), were synthesized by the coupling of two chiral blocks with a methyl branch at the 2- or 3-position. The blocks were prepared by applying the stereospecific inversion of secondary tosylates, which were derived from (R)- and (S)-propylene oxide, and their enantiopurities were confirmed by chiral HPLC analysis.
Highly efficient copper(I) iodide-tolyl-BINAP-catalyzed asymmetric conjugate addition of methylmagnesium bromide to α,β-unsaturated esters
Wang, Shun-Yi,Lum, Tze-Keong,Ji, Shun-Jun,Loh, Teck-Peng
supporting information; experimental part, p. 673 - 677 (2009/04/10)
A highly efficient asymmetric conjugate addition of methylmagnesium bromide (MeMgBr) to α,β-unsaturated esters catalyzed by copper(I) iodide-tolyl-BNIP (CuI-Tol-BINAP) is described.
Asymmetric Conjugate Addition of Organometallic Reagents to Chiral Vinyl Sulfoximines
Pyne, Stephen G.
, p. 81 - 87 (2007/10/02)
The chiral vinyl sulfoximines 1 and 2 (R' = C6H5, CH3, n-Bu, C6H5CH2CH2) have been prepared; they undergo conjugate addition reactions with organometallic reagents with high asymmetric induction.These conjugate addition adducts have been converted to chiral 3-alkylalkanoic acids in high enantiomeric excess (>90percent)