99455-14-8

Basic information

• Product Name: 8-broMo-2-chloro-6-Methylquinoline
• Synonyms: 8-broMo-2-chloro-6-Methylquinoline;6-BroMo-2-chloro-8-Methylquinoline
• CAS NO: 99455-14-8
• Molecular Formula: C₁₀H₇BrClN
• Molecular Weight: 256.52628
• Mol File: 99455-14-8.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 8-broMo-2-chloro-6-Methylquinoline(CAS DataBase Reference)
• NIST Chemistry Reference: 8-broMo-2-chloro-6-Methylquinoline(99455-14-8)
• EPA Substance Registry System: 8-broMo-2-chloro-6-Methylquinoline(99455-14-8)

Safety Data

• Hazardous Substances Data: 99455-14-8(Hazardous Substances Data)

Usage

Description

8-bromo-2-chloro-6-methylquinoline, a quinoline derivative with the molecular formula C11H8BrClN, is a chemical compound featuring a quinoline ring with a bromine atom at the 8th position, a chlorine atom at the 2nd position, and a methyl group at the 6th position. 8-broMo-2-chloro-6-Methylquinoline is known for its potential biological and pharmacological activities, making it a valuable asset in pharmaceutical research and development.

Uses

Used in Pharmaceutical Research and Development:
8-bromo-2-chloro-6-methylquinoline serves as a promising candidate in pharmaceutical research due to its demonstrated antibacterial and antiviral properties. It is being investigated for its potential application in treating a variety of diseases, offering a new avenue for therapeutic intervention.
Used as an Intermediate in Chemical Synthesis:
In the pharmaceutical industry, 8-bromo-2-chloro-6-methylquinoline also plays a crucial role as an intermediate in the synthesis of other chemical compounds. Its unique structure and functional groups make it a versatile building block for creating new and improved pharmaceutical agents, contributing to the advancement of medicinal chemistry.

Upstream product

• 701285-95-2 6-bromo-1,8-dimethyl-1H-quinolin-2-one 
• 99465-08-4 6-bromo-8-methyl-2(1H)-quinolinone 
• 583-75-5 4-Bromo-2-methylaniline 
• 99465-17-5 trans-N-(4-bromo-2-methylphenyl)-3-ethoxy-2-propenamide 
• 178396-31-1 6-bromo-8-methylquinoline 
• 89446-45-7 6-bromo-4,8-dimethyl-2-quinolone 

Downstream Products

• 99465-08-4 6-bromo-8-methyl-quinolin-2-ol 
• 858467-33-1 6-bromo-2-chloro-8-methyl-[5]quinolylamine 
• 854834-69-8 5-amino-6-bromo-8-methyl-quinolin-2-ol 

Relevant articles and documents

6-heteroaryl quinolone inotropic agents

A series of novel heterocyclic-substituted 2-(1H)-quinolone compounds have been prepared, including the 3,4-dihydro derivatives thereof, wherein the heterocyclic ring moiety is a pyrrolyl, imidazolyl, pyrazolyl, triazolyl or tetrazolyl group attached by a nitrogen atom of said group to the 5-, 6-, 7- or 8-positions of the quinolone ring. These particular compounds are useful in therapy as highly potent inotropic agents and therefore, are of value in the treatment of various cardiac conditions. Preferred member compounds include 6-(2,4-dimethylimidazol-1-yl)-8-methyl-2-(1H)-quinolone, 6-(2,4-dimethyl-5-nitroimadazol-1-yl)-8-methyl-2-(1H)-quinolone, 8-methyl-6-(tetrazol-1-yl)-2-(1H)-quinolone, 8-methyl-6-(1,2,4-triazol-4-yl)-2-(1H)-quinolone, and 6-(4-cyano-2-methylimidazol-1-yl)-8-methyl-2-(1H)-quinolone, respectively. Methods for preparing these compounds from known starting materials are provided.

Quinolone inotropic agents

A series of novel phenyl-substituted 2-(1H)-quinolone compounds have been prepared, including the 3,4-dihydro derivatives thereof, wherein the phenyl ring moiety is a mono-or di-substituted phenyl group attached to the 5-, 6-, 7- or 8-positions of the qui