99471-67-7Relevant articles and documents
MITOCHONDRIAL COMPLEX I INHIBITORS AND METHODS OF USE
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Paragraph 0123-0125, (2021/03/19)
Disclosed herein are methods of using mitochondrial complex I inhibitors in the treatment of a disease or condition that would benefit from the inhibition of mitochondrial respiration. Also described herein are methods of treating a disease or condition s
High birefringence bistolane liquid crystals: Synthesis and properties
W?g?owska, Dorota,Kula, Przemys?aw,Herman, Jakub
, p. 403 - 408 (2016/01/09)
Twenty liquid crystals both symmetrical and non-symmetrical bistolanes with terminal alkyl, alkoxy and alkylsulfanyl chain and lateral methyl or ethyl group have been synthesized via Sonogashira cross-coupling and their mesomorphic properties have been studied. Most compounds exhibit an enantiotropic nematic phase in a broad temperature range (>40 °C). Optical properties of selected compounds have been investigated. They exhibit a high value of birefringence (>0.4).
Modular synthesis of triazole-containing triaryl α-helix mimetics
Ehlers, Ina,Maity, Prantik,Aube, Jeffrey,Koenig, Burkhard
scheme or table, p. 2474 - 2490 (2011/06/10)
We describe novel scaffold designs for nonpeptidic α-helix mimetics. The tricyclic scaffolds contain triazoles and reproduce amino acid side chains i, i+3, and i+7. The three different scaffolds are synthetically readily accessible, allow the introduction