99483-18-8Relevant articles and documents
Synthesis of allylarenes via catalytic decarboxylation of allyl benzoates
Pfister, Kai F.,Grünberg, Matthias F.,Goossen, Lukas J.
, p. 3302 - 3306 (2014)
A catalyst system consisting of the palladium(0) complex Pd2(dba)3 and tri(p-tolyl) phos-phine was found to efficiently promote the decarboxylation of allyl benzoates with formation of allylarenes. This catalytic C-O activation followed by extrusion of carbon dioxide and C-C bond formation represents a sustainable alternative to traditional waste-intensive cross-couplings. The scope of the transformation includes allyl and cinnamyl esters of various ortho-substituted benzoic acids. For particularly activated substrates, the palladium catalyst can optionally be replaced by an inexpensive nickel complex.
