99512-42-2

Basic information

• Product Name: methyl 5-oxo-3-phenylhexanoate
• Synonyms: methyl 5-oxo-3-phenylhexanoate
• CAS NO: 99512-42-2
• Molecular Weight: 220.268
• Mol File: 99512-42-2.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: methyl 5-oxo-3-phenylhexanoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 5-oxo-3-phenylhexanoate(99512-42-2)
• EPA Substance Registry System: methyl 5-oxo-3-phenylhexanoate(99512-42-2)

Safety Data

• Hazardous Substances Data: 99512-42-2(Hazardous Substances Data)

Upstream product

• 67-56-1 methanol 
• 1261085-79-3 5-benzoyl-6-methyl-4-phenyl-3,4-dihydro-2H-pyran-2-one 
• 104-55-2 3-phenyl-propenal 
• 1261085-76-0 5-acetyl-6-methyl-4-phenyl-3,4-dihydro-2H-pyran-2-one 
• 493-72-1 5-phenyl-cyclohexane-1,3-dione 
• 18107-18-1 diazomethyl-trimethyl-silane 
• 131119-24-9 3-Benzylidene-1,5-dioxa-spiro[5.5]undecane-2,4-dione 
• 4354-90-9 (3-oxo-1-phenyl-butyl)-malonic acid 
• 118527-80-3 (4R,6S)-4-Phenyl-6-trimethylsilanyl-oxepan-2-one 
• 116428-46-7 trans-3-phenyl-5-(trimethylsilyl)-cyclohexanone 
• 92912-02-2 3-phenyl-6-methylidenetetrahydro-2-pyranone 
• 18365-23-6 methyl 2-(tributylstannyl)acetate 
• 1896-62-4 (E)-benzalacetone 
• 103-26-4 Methyl cinnamate 

Downstream Products

• 1008-73-7 4-phenyldihydrofuran-2(3H)-one 
• 344596-97-0 5,5-Dimethoxy-3-phenyl-hexanoic acid methyl ester 

Relevant articles and documents

DBU-Catalyzed Ring-Opening and Retro-Claisen Fragmentation of Dihydropyranones

We present a general protocol for the formal Michael addition of acetone to α,β-unsaturated esters and amides, a transformation difficult to perform using current methods. The protocol comprises of an amidine catalyzed relay ring-opening and fragmentation

Highly regioselective addition of an ester enolate equivalent to α,β-unsaturated ketones: Selective formation of both isomers derived from 1,2- and 1,4-additions using α-stannyl ester with additives

The reaction of α-stannyl ester with α,β-unsaturated ketones in the presence of stannous chloride (SnCl2) and chlorosilanes (Me3SiCl or Me2SiCl2) gave 1,2- and 1,4-addition products, respectively.

3-Substituted-γ-butyrolactones from 5-Trimethylsilyl-2-cyclohexenone. Synthesis of (-)-Enterolactone

1,4-Adducts of 5-trimethylsilyl-2-cyclohexenone (1) with Grignard reagents were converted to various hexanoate derivatives and γ-butyrolactones.Starting from optically pure 1, (-)-enterolactone (Factor X) was synthesized.