99614-03-6

Basic information

• Product Name: Ondansetron HCl IMpurity-G
• Synonyms: Ondansetron HCl IMpurity-G;1,2,3,9-Tetrahydro-3-(1H-imidazol-1-ylmethyl)-9-methyl-4H-carbazol-4-one (Ondansetron Impurity G);1,2,3,9-Tetrahydro-3-(1H-imidazol-1-ylmethyl)-9-methyl-4H-carbazol-4-one
• CAS NO: 99614-03-6
• Molecular Formula: C17H17N3O
• Molecular Weight: 279.33638
• Mol File: 99614-03-6.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• Storage Temp.: Room Temperature
• Solubility: Acetonitrile (Slightly), Chloroform (Slightly), DMSO (Slightly)
• CAS DataBase Reference: Ondansetron HCl IMpurity-G(CAS DataBase Reference)
• NIST Chemistry Reference: Ondansetron HCl IMpurity-G(99614-03-6)
• EPA Substance Registry System: Ondansetron HCl IMpurity-G(99614-03-6)

Safety Data

• Hazardous Substances Data: 99614-03-6(Hazardous Substances Data)

Usage

Description

c-Desmethylondansetron, also known as Ondansetron Impurity G, is a metabolite of Ondansetron (O655000). It is a selective 5-hydroxytryptamine3 (5-HT3) receptor antagonist that has been introduced to clinical practice as an antiemetic for cancer treatment-induced and anesthesia-related nausea and vomiting.

Uses

Used in Pharmaceutical Industry:
c-Desmethylondansetron is used as an antiemetic agent for the treatment of nausea and vomiting caused by cancer treatment and anesthesia. It works by selectively blocking the 5-HT3 receptors, which play a crucial role in the vomiting reflex. This helps to alleviate the symptoms and improve the quality of life for patients undergoing these treatments.