99765-76-1

Basic information

• Product Name: 2-(methoxycarbonyl)-4-(methylthio)-4-(p-tolylsulfonyl)cyclohexanone
• Synonyms: 2-(methoxycarbonyl)-4-(methylthio)-4-(p-tolylsulfonyl)cyclohexanone
• CAS NO: 99765-76-1
• Molecular Weight: 356.464
• Mol File: 99765-76-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-(methoxycarbonyl)-4-(methylthio)-4-(p-tolylsulfonyl)cyclohexanone(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(methoxycarbonyl)-4-(methylthio)-4-(p-tolylsulfonyl)cyclohexanone(99765-76-1)
• EPA Substance Registry System: 2-(methoxycarbonyl)-4-(methylthio)-4-(p-tolylsulfonyl)cyclohexanone(99765-76-1)

Safety Data

• Hazardous Substances Data: 99765-76-1(Hazardous Substances Data)

Upstream product

• 59662-65-6 methylthiomethyl p-tolyl sulfone 
• 292638-85-8 acrylic acid methyl ester 

Downstream Products

• 99765-84-1 2-benzyl-2-(methoxycarbonyl)-4-(methylthio)-4-(p-tolylsulfonyl)cyclohexanone 
• 99783-12-7 2-benzyl-2-(methoxycarbonyl)-1,4-cyclohexanedione 
• 99765-85-2 methyl 1-allyl-2,5-dioxocyclohexane-1-carboxylate 
• 99765-82-9 2-allyl-2-(methoxycarbonyl)-4-(methylthio)-4-(p-tolylsulfonyl)cyclohexanone 
• 2150-46-1 Methyl 2,5-dihydroxybenzoate 
• 27024-89-1 2-(methoxycarbonyl)-1,4-cyclohexanedione 

Relevant articles and documents

Addition of (Methylthio)methyl p-Tolyl Sulfone to α,β-Unsaturated Carbonyl Compounds

The lithio derivative of (methylthio)methyl p-tolyl sulfone (1) reacted with various α,β-unsaturated carbonyl compounds to afford adducts in good to high yields.The introduced (methylthio)(p-tolylsulfonyl)methyl group was easily converted to a (methylthio)carbonyl group or a formyl group.When the reaction of 1 with methyl acrylate using sodium hydride as a base was performed in DMF at an ambient temperature,2-(methoxycarbonyl)-4-(methylthio)-4-(p-tolylsulfonyl)cyclohexanone (8) was obtained in 81 percent yield.Furthermore, 8 was shown to be an important intermediate for preparing 2-substituted 2-(methoxycarbonyl)-1,4-cyclohexanediones.