99859-25-3

Basic information

• Product Name: levulinic acid-(4-bromo-anilide)
• Synonyms: levulinic acid-(4-bromo-anilide)
• CAS NO: 99859-25-3
• Molecular Weight: 270.126
• Mol File: 99859-25-3.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: levulinic acid-(4-bromo-anilide)(CAS DataBase Reference)
• NIST Chemistry Reference: levulinic acid-(4-bromo-anilide)(99859-25-3)
• EPA Substance Registry System: levulinic acid-(4-bromo-anilide)(99859-25-3)

Safety Data

• Hazardous Substances Data: 99859-25-3(Hazardous Substances Data)

Upstream product

• 57681-51-3 5-acetyloxy-dihydro-5-methyl-2(3H)-furanone 
• 106-40-1 4-bromo-aniline 
• 23132-35-6 levulinanilide 
• 79-37-8 oxalyl dichloride 
• 123-76-2 levulinic acid 
• 6089-09-4 4-pentynoic acid 
• 1490-24-0 4-oxo-pentanoyl chloride 

Downstream Products

• 99853-07-3 levulinic acid-(4-bromo-2-nitro-anilide) 
• 1439402-14-8 1-(4-bromophenyl)-5-methylpyrrolidin-2-one 
• 280120-31-2 N-[4-bromophenyl]-4-hydroxypentylamine 
• 100125-75-5 levulinic acid-(2-amino-4-bromo-anilide) 

Relevant articles and documents

Combination of Metal-Catalyzed Cycloisomerizations and Biocatalysis in Aqueous Media: Asymmetric Construction of Chiral Alcohols, Lactones, and γ-Hydroxy-Carbonyl Compounds

The combination of the metal-catalyzed cycloisomerization of alkynes containing a tethered nucleophile as substituent in aqueous media (followed by the spontaneous hydrolysis, hydroalkoxylation, or aminolysis of the transiently formed five-membered heterocycles) with the subsequent enantioselective ketone bioreduction (mediated by KREDs) has been achieved. The overall transformations, which formally involve a three-step one-pot reaction, provide a variety of enantiopure valuable molecules (e.g., 1,4-diols, lactones, and γ-hydroxy-carbonyl compounds (carboxylic acids, esters, and amides)) with high conversions and enantioselectivities and under mild reaction conditions, disclosing the concept of integrated metal-catalyzed cycloisomerizations of alkynes and enzymatic catalysis in water.

Nitrogen containing heterobicycles as factor Xa inhibitors

The present application describes nitrogen containing heterobicyclics and derivatives thereof, or pharmaceutically acceptable salt forms thereof, which are useful as inhibitors of factor Xa.