99969-02-5Relevant articles and documents
PYRAZINES, PYRIMIDINES AND PYRIDAZINES USEFUL IN THE TREATMENT OF SENILE DEMENTIA
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, (2008/06/13)
The present invention provides pyrazines, pyridazines or pyrimidines, or salts or prodrugs thereof, substituted on one of the ring carbon atoms thereof with a non-aromatic azacyclic or azabicyclic ring system; and independently substituted on each of the other ring carbon atoms with a substituent of low lipophilicity or a hydrocarbon substituent; which compounds stimulate central muscarinic acetylcholine receptors and therefore are useful in the treatment of neurological and mental illnesses.