99973-98-5

Basic information

• Product Name: 3-nitro-4-(phenylthio)pyridine
• Synonyms: 3-nitro-4-(phenylthio)pyridine
• CAS NO: 99973-98-5
• Molecular Weight: 232.263
• Mol File: 99973-98-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-nitro-4-(phenylthio)pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 3-nitro-4-(phenylthio)pyridine(99973-98-5)
• EPA Substance Registry System: 3-nitro-4-(phenylthio)pyridine(99973-98-5)

Safety Data

• Hazardous Substances Data: 99973-98-5(Hazardous Substances Data)

Upstream product

• 13091-23-1 4-chloro-3-nitropyridine 
• 108-98-5 thiophenol 
• 5435-54-1 4-hydroxy-3-nitropyridine 
• 108-96-3 4-pyridone 

Downstream Products

• 261-92-7 10H-pyrido<4,3-b><1,4>benzothiazine 
• 103984-11-8 4-(phenylthio)pyridin-3-amine 

Relevant articles and documents

Discovery of Novel Tricyclic Thiazepine Derivatives as Anti-Drug-Resistant Cancer Agents by Combining Diversity-Oriented Synthesis and Converging Screening Approach

An efficient discovery strategy by combining diversity-oriented synthesis and converging cellular screening is described. By a three-round screening process, we identified novel tricyclic pyrido[2,3-b][1,4]benzothiazepines showing potent inhibitory activity against paclitaxel-resistant cell line H460TaxR (EC50 50 > 100 μM against normal human fibroblasts). The most active hits also exhibited drug-like properties suitable for further preclinical research. This redeployment of antidepressing compounds for anticancer applications provides promising future prospects for treating drug-resistant tumors with fewer side effects.