high purity 2-Deoxy...

high purity 2-Deoxy-D-glucose CAS:154-17-6

high purity 2-Deoxy-D-glucose CAS:154-17-6

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0 Metric Ton

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  • Purity: 99%

Keywords

2-Deoxy-D-glucose CAS:154-17-6

Quick Details

  • Appearance:white powders
  • Application:2-deoxy-D-Glucose is a non-metabolizable glucose analog that inhibits phosphorylation of glucose by hexokinase, the first step of glycolysis.1,2 This results in the depletion in cellular ATP, the inhi
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  • Storage:at room temperature
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Specifications

high purity 2-Deoxy-D-glucose cas 154-17-6

 

 

 

 

 

 

 

 

 

 

 

 

 

2-Deoxy-D-glucose 

 

 

 

Product Description

 

  

Description
2-deoxy-D-Glucose is a non-metabolizable glucose analog that inhibits phosphorylation of glucose by hexokinase, the first step of glycolysis.1,2 This results in the depletion in cellular ATP, the inhibition of protein glycosylation, and the disruption of ER quality control by inducing the unfolded protein response.2-deoxy-D-Glucose has been shown to cause cell cycle inhibition and cell death in in vitro models of hypoxia, induce autophagy, increase reactive oxygen species production, activate AMPK, and block tumor cell growth in animal models.

 

 

 

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  high purity 2-Deoxy-D-glucose cas 154-17-6  high purity 2-Deoxy-D-glucose cas 154-17-6

 

 

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