UNC0631/ supplier with competitive price in stock-Rechems

Details:

UNC 0631 is a potent G9a inhibitor with IC50 value of 4 nM.IC50 value: 4 nM Target: G9a UNC 0631, which had high in vitro potency versus G9a and improved lipophilicity, was highly potent (IC50 < 0.06 μM) in reducing H3K9me2 levels in MDA-MB-231 cells and had low cell toxicity.In particular, compounds 7 was more potent than compound 5 and had a similar tox/function ratio in MDAMB-231 cells.UNC 0631 showed excellent separation of functional potency versus cell toxicity in MDA-MB-231 cells, thecompound was further evaluated in a variety of cell lines to characterize it's cellular potency and cell toxicity.UNC 0631 had excellent tox/function ratios in these cell lines.
Shanghai Rechem science Co., Ltd.
Rechemsis focus on R&D of new APIS, signal transduction inhibitors and pharmaceutical intermediates. We follow closely the industry trend, and the latest research achievements in life science area.
Rechems is located in the largest biomedical base in China--Shanghai and cooperatively established modern production base and laboratory in surrounding areas. We have built up a good relationship with many US / European / Japanese pharmaceutical companies to conduct chemical research and inventory trading in medicinal chemistry.
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