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Dayang Chem (Hangzhou) Co.,Ltd.

DayangChem exported this product to many countries and regions at best price. If you are looking for the material's manufacturer or supplier in China, DayangChem is your best choice. Pls contact with us freely for getting detailed product spe

Sulfamethizole

Cas:144-82-1

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

Factory Price API 99% SULFAMETHIZOLE 144-82-1 GMP Manufacturer

Cas:144-82-1

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

Sulfamethizole

Cas:144-82-1

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

Our Advantage Rich Experience Our products are sold all over Europe,North&South America, Sino-East, Asia and pacific area as well as Africa,we establish long term. Quality service Company cooperates with research institutes. We strictly con

144-82-1 SULFAMETHIZOLE

Cas:144-82-1

Min.Order:1 Kilogram

FOB Price: $15.0 / 50.0

Type:Trading Company

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Wholesale price CAS 144-82-1 with best price

Cas:144-82-1

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

inquiry

Shanghai Upbio Tech Co.,Ltd

1.In No Less 10 years exporting experience. you can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specializ

Benzenesulfonamide,4-amino-N-(5-methyl-1,3,4-thiadiazol-2-yl)-

Cas:144-82-1

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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LIDE PHARMACEUTICALS LIMITED

Advantage : LIDE PHARMACEUTICALS LTD. is a mid-small manufacturing-type enterprise, engaged in pharmaceutical intermediates of R&D, custom-made and production, and also involving trading chemicals for export. We have established the R&amp

Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

SULFAMETHIZOLE

Cas:144-82-1

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Afine Chemicals Limited

Company Introduction 1. Established in 2005, with two independent business divisions: Fine chemicals division; Pharmaceutical division. 2. Main product: Optical brightener Textile auxiliary Dye stuff Pigments

SULFAMETHIZOLE

Cas:144-82-1

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

Benzenesulfonamide,4-amino-N-(5-methyl-1,3,4-thiadiazol-2-yl)-

Cas:144-82-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

TaiChem Taizhou Limited

Established in May 2015, TaiChem Ltd. is initially invested by a British research and development company and started by PhDs back from aboard. The company is registered in China Medical City (CMC), Taizhou, Jiangsu Province, and the production site

SULFAMETHIZOLE

Cas:144-82-1

Min.Order:10 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Xiamen Jenny Chemical Technology Co., Ltd.

GMP standard, high purity, competitive price, in stock 1. Quick Response: within 6 hours after receiving your email. 2. Quality Guarantee: All products are strictly tested by our QC, confirmed by QA, and approved by a third-party lab in China, USA,

Sulfamethizole;4-amino-N-(5-methyl-1,3,4-thiadiazol-2-yl)-benzenesulfonamide

Cas:144-82-1

Min.Order:1 Milligram

Negotiable

Type:Trading Company

inquiry

TAIZHOU ZHENYU BIOTECHNOLOGY CO., LTD

Zhenyu biotech exported this product to many countries and regions at best price. if you are looking for the material's manufacturer or supplier in china, zhenyu biotech is your best choice. pls contact with us freely for getting detailed

SULFAMETHIZOLE

Cas:144-82-1

Min.Order:1 Kilogram

FOB Price: $2.0

Type:Lab/Research institutions

inquiry

Win-Win chemical Co.Ltd

Stock products, own laboratoryAppearance:White to light yellow crystalline powder Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai

SULFAMETHIZOLE Cas no.144-82-1 98%

Cas:144-82-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

GIHI CHEMICALS CO.,LIMITED

Lower price, sample is available,SDS test documents are available,large stock in warehouseAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:Fine chemical intermediates, used as the main raw material for the synthe

Sulfamethizole

Cas:144-82-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Kono Chem Co.,Ltd

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air Port:Beijing or Guangzhou

sulfamethizole

Cas:144-82-1

Min.Order:0

Negotiable

Type:Other

inquiry

Sinoway Industrial Co., Ltd.

Why is SINOWAY:1) Specialized in pharmaceutical and healthcare industrial since 19872) ISO 9001:2015 & SGS audited supplier . 3) Accept various payment terms : T.T 30-60 days.4) We have warehouse in USA with quickly shipment .5) We can do different t

99% up by HPLC SULFAMETHIZOLE 144-82-1

Cas:144-82-1

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Shanghai Acmec Biochemical Technology Co., Ltd.

Acmec is a leading manufacturer and supplier of biochemical reagents and life science products. We have over 40,000 items in stock (real-time inventory) and offer discounted prices to registered members of the online store ( www.acmec.com.cn ) Appea

Acmec Sulfamethizole S87600 250mg

Cas:144-82-1

Min.Order:1 bottle

Negotiable

Type:Lab/Research institutions

inquiry

Henan Allgreen Chemical Co.,Ltd

high quality Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea

Sulfamethizole (200 mg)

Cas:144-82-1

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Xi`an Eastling Biotech Co., Ltd.

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:Foil bag; Drum; Plastic bottle Application:Pharma;Industry;Agricultural Transportation:by sea or air Port:Beijing or Guangzhou

SULFAMETHIZOLE

Cas:144-82-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Huarong Pharm Co., Ltd.

High qualityAppearance:White powder Storage:Room temperature Package:Aluminum bag Application:Used in producing API Transportation:By air Port:Beijing

Sulfamethizol

Cas:144-82-1

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Henan Tianfu Chemical Co., Ltd.

Good quantity Storage:R.T. Package:as per buyers Application:intermediate Transportation:by air/sea

SULFAMETHIZOLE

Cas:144-82-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Antimex Chemical Limied

SulfamethizoleAppearance:detailed see specifications Storage:Keep away of light, cool place Package:25kg/drum;200kg/drum Application:Used in Synthesis, Pharmaceuticals and other fields Transportation:Sea/air/courier

Sulfamethizole

Cas:144-82-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Sartort Biopharma Co., Ltd

Best quality with low priceAppearance:white to pale yellow crystalline powder Storage:ln stock Package:25kg/Barrel Application:Chemicals Transportation:Express/Sea/Air Port:Shanghai

sulfamethizole

Cas:144-82-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

BOC Sciences

BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds. Package:

Sulfamethizole

Cas:144-82-1

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Shanghai Yuanye Bio-Technology Co., Ltd.

good quality, competitive price, thoughtful after sale serviceAppearance:white powder Storage:Keep it in dry,shady and cool place Package:1.2ml Application:Pharma;Industry;Agricultural;chemical reaserch Transportation:by express or by sea Port:Any po

Sulfamethizole

Cas:144-82-1

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

home-produced Application:medicine

SULFAMETHIZOLE

Cas:144-82-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

ZHEJIANG JIUZHOU CHEM CO.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

SULFAMETHIZOLE

Cas:144-82-1

Min.Order:0

Negotiable

Type:Trading Company

inquiry

LEAP CHEM Co., Ltd.

Best Seller, High Quality, Competitive Price, Fast Delivery, Quick ResponseAppearance:powder, or liquid Storage:Stored in room temperature, ventilated place Package:Bottle, barrel, cargo, container, etc. Application:Pharmaceuticals, intermediates, AP

SULFAMETHIZOLE

Cas:144-82-1

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Amadis Chemical Co., Ltd.

1.Professional synthesis laboratory and production base. 2.Strong synthesis team and service team. 3.Professional data management system. 4.We provide the professional test date and product information ,ex. HNMR ,CNMR,FNMR, HPLC/G

Sulfamethizole

Cas:144-82-1

Min.Order:10 Milligram

Negotiable

Type:Lab/Research institutions

inquiry

Synthetic route

N-(5-methyl-1,3,4-thiadiazol-2-yl)-4-nitrobenzenesulfonamide
349621-24-5

N-(5-methyl-1,3,4-thiadiazol-2-yl)-4-nitrobenzenesulfonamide

sulfamethizole
144-82-1

sulfamethizole

Conditions
ConditionsYield
With hydrogenchloride; iron In ethanol; water for 3h; Reflux;100%
N-(4-(N-(5-methyl-1,3,4-thiadiazol-2-yl)sulfamoyl)phenyl)acetamide
39719-87-4

N-(4-(N-(5-methyl-1,3,4-thiadiazol-2-yl)sulfamoyl)phenyl)acetamide

sulfamethizole
144-82-1

sulfamethizole

Conditions
ConditionsYield
Stage #1: N-(4-(N-(5-methyl-1,3,4-thiadiazol-2-yl)sulfamoyl)phenyl)acetamide With hydrogenchloride In water for 0.5h; Reflux;
Stage #2: With sodium carbonate In water
72%
Stage #1: N-(4-(N-(5-methyl-1,3,4-thiadiazol-2-yl)sulfamoyl)phenyl)acetamide With hydrogenchloride In water for 0.5h; Reflux;
Stage #2: With sodium carbonate In water
72%
With hydrogenchloride
With sodium hydroxide
5-methyl-1,3,4-thiadiazol-2-amine
108-33-8

5-methyl-1,3,4-thiadiazol-2-amine

4-Nitrobenzenesulfonyl chloride
98-74-8

4-Nitrobenzenesulfonyl chloride

sulfamethizole
144-82-1

sulfamethizole

Conditions
ConditionsYield
anschliessend Erwaermen mit Eisen in wss.-aethanol. HCl;
5-methyl-1,3,4-thiadiazol-2-amine
108-33-8

5-methyl-1,3,4-thiadiazol-2-amine

p-acetylaminobenzenesulfonyl chloride
121-60-8

p-acetylaminobenzenesulfonyl chloride

sulfamethizole
144-82-1

sulfamethizole

Conditions
ConditionsYield
With pyridine anschliessend Erwaermen mit wss. NaOH;
With hydrogenchloride
acetaldehyde thiosemicarbazone
2302-95-6

acetaldehyde thiosemicarbazone

p-acetylaminobenzenesulfonyl chloride
121-60-8

p-acetylaminobenzenesulfonyl chloride

sulfamethizole
144-82-1

sulfamethizole

Conditions
ConditionsYield
With pyridine anschliessend Erwaermen mit Ca32 in wss.-alkal. Loesung;
acetyl chloride
75-36-5

acetyl chloride

1-acetyl-4-<N-acetyl-sulfanilyl>-thiosemicarbazide

1-acetyl-4-<N-acetyl-sulfanilyl>-thiosemicarbazide

sulfamethizole
144-82-1

sulfamethizole

Conditions
ConditionsYield
anschliessend Hydrolysieren mit Mineralsaeure;
p-acetylaminobenzenesulfonyl chloride
121-60-8

p-acetylaminobenzenesulfonyl chloride

sulfamethizole
144-82-1

sulfamethizole

Conditions
ConditionsYield
Multi-step reaction with 2 steps
2: aqueous HCl
View Scheme
Multi-step reaction with 2 steps
1: pyridine / 1 h / 95 °C
2: hydrogenchloride / water / 0.5 h / Reflux
View Scheme
Multi-step reaction with 2 steps
1: pyridine / 0 - 95 °C
2: hydrogenchloride / water / 0.5 h / Reflux
View Scheme
4-Nitrobenzenesulfonyl chloride
98-74-8

4-Nitrobenzenesulfonyl chloride

sulfamethizole
144-82-1

sulfamethizole

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: dichloromethane; pyridine / 2 h / 20 °C
2: hydrogenchloride / iron / ethanol; water / 3 h / Reflux
View Scheme
sulfamethizole
144-82-1

sulfamethizole

2,3-isopropylidene-glyceraldehyde
15186-48-8

2,3-isopropylidene-glyceraldehyde

4-({[(4S)-2,2-dimethyl-1,3-dioxolan-4-yl]methylene}amino)-N-(5-methyl-1,3,4-thiadiazol-2-yl)benzenesulfonamide

4-({[(4S)-2,2-dimethyl-1,3-dioxolan-4-yl]methylene}amino)-N-(5-methyl-1,3,4-thiadiazol-2-yl)benzenesulfonamide

Conditions
ConditionsYield
With toluene-4-sulfonic acid In dimethyl sulfoxide; toluene Condensation;100%
sulfamethizole
144-82-1

sulfamethizole

methyl 3-formyl-5-iodobenzoate

methyl 3-formyl-5-iodobenzoate

methyl 3-iodo-5-((4-(N-(5-methyl-1,3,4-thiadiazol-2-yl)sulfamoyl)phenylamino)-methyl)benzoate

methyl 3-iodo-5-((4-(N-(5-methyl-1,3,4-thiadiazol-2-yl)sulfamoyl)phenylamino)-methyl)benzoate

Conditions
ConditionsYield
With sodium tris(acetoxy)borohydride; acetic acid In dichloromethane at 20℃;99%
2,3-Dichloro-1,4-naphthoquinone
117-80-6

2,3-Dichloro-1,4-naphthoquinone

sulfamethizole
144-82-1

sulfamethizole

4-(3-chloro-1,4-dioxo-1,4-dihydronaphthalen-2-ylamino)-N-(5-methyl-1,3,4-thiadiazol-2-yl)benzenesulfonamide
1204290-30-1

4-(3-chloro-1,4-dioxo-1,4-dihydronaphthalen-2-ylamino)-N-(5-methyl-1,3,4-thiadiazol-2-yl)benzenesulfonamide

Conditions
ConditionsYield
In ethanol at 115℃; for 72h;98%
tetrafluoroboric acid

tetrafluoroboric acid

sulfamethizole
144-82-1

sulfamethizole

sodium nitrite
7632-00-0

sodium nitrite

C9H8N5O2S2(1+)*BF4(1-)

C9H8N5O2S2(1+)*BF4(1-)

Conditions
ConditionsYield
In water at 0℃; for 0.75h; Inert atmosphere;96%
sulfamethizole
144-82-1

sulfamethizole

n-decanoyl chloride
112-13-0

n-decanoyl chloride

N-(4-(N-(5-methyl-1,3,4-thiadiazol-2-yl)sulfamoyl)phenyl)decanamide
1191951-65-1

N-(4-(N-(5-methyl-1,3,4-thiadiazol-2-yl)sulfamoyl)phenyl)decanamide

Conditions
ConditionsYield
With pyridine at 95℃; for 1h;95%
With pyridine at 0 - 95℃;95%
5-bromo-3-methoxysalicylaldehyde
5034-74-2

5-bromo-3-methoxysalicylaldehyde

sulfamethizole
144-82-1

sulfamethizole

(E)-4-((5-bromo-2-hydroxy-3-methoxy benzylidene)amino)-N-(5-methyl-1,3,4-thiadiazol-2-yl)benzenesulfonamide

(E)-4-((5-bromo-2-hydroxy-3-methoxy benzylidene)amino)-N-(5-methyl-1,3,4-thiadiazol-2-yl)benzenesulfonamide

Conditions
ConditionsYield
With toluene-4-sulfonic acid In ethanol at 78℃; for 6h;92%
sulfamethizole
144-82-1

sulfamethizole

Methacryloyl chloride
920-46-7

Methacryloyl chloride

methacryloyl sulfamethizole

methacryloyl sulfamethizole

Conditions
ConditionsYield
With sodium hydroxide In water; acetone at 20℃; for 1.5h; Cooling with ice;91%
5-bromosalicyclic acid
89-55-4

5-bromosalicyclic acid

sulfamethizole
144-82-1

sulfamethizole

(E)-4-((5-bromo-2-hydroxybenzylidene)amino)-N-(5-methyl-1,3,4-thiadiazol-2-yl)benzenesulfonamide

(E)-4-((5-bromo-2-hydroxybenzylidene)amino)-N-(5-methyl-1,3,4-thiadiazol-2-yl)benzenesulfonamide

Conditions
ConditionsYield
With toluene-4-sulfonic acid In ethanol at 78℃; for 6h;90%
1,8-Naphthalic anhydride
81-84-5

1,8-Naphthalic anhydride

sulfamethizole
144-82-1

sulfamethizole

4-(1,3-dioxo-1H-benzo[de]isoquinolin-2(3H)-yl)-N-(5-methyl-1,3,4-thiadiazol-2-yl)benzenesulfonamide

4-(1,3-dioxo-1H-benzo[de]isoquinolin-2(3H)-yl)-N-(5-methyl-1,3,4-thiadiazol-2-yl)benzenesulfonamide

Conditions
ConditionsYield
With triethylamine In ethanol at 80℃; for 10h;85%
4-chlorobenzoquinazoline
33987-02-9

4-chlorobenzoquinazoline

sulfamethizole
144-82-1

sulfamethizole

4-(benzo[g]quinazolin-4-ylamino)-N-(5-methyl-1,3,4-thiadiazol-2yl)benzenesulfonamide

4-(benzo[g]quinazolin-4-ylamino)-N-(5-methyl-1,3,4-thiadiazol-2yl)benzenesulfonamide

Conditions
ConditionsYield
With triethylamine In N,N-dimethyl-formamide for 24h; Reflux;82%
2-chloro-6-methylnicotinonitrile
28900-10-9

2-chloro-6-methylnicotinonitrile

sulfamethizole
144-82-1

sulfamethizole

4-(3-cyano-6-methylpyridin-2-ylamino)-N-(5-methyl-1,3,4-thiadiazol-2-yl)benzenesulfonamide

4-(3-cyano-6-methylpyridin-2-ylamino)-N-(5-methyl-1,3,4-thiadiazol-2-yl)benzenesulfonamide

Conditions
ConditionsYield
With triethylamine In N,N-dimethyl-formamide for 18h; Reflux;82%
2-chloromethyl-1H-benzimidazole
4857-04-9

2-chloromethyl-1H-benzimidazole

sulfamethizole
144-82-1

sulfamethizole

4-[(1H-Benzoimidazol-2-ylmethyl)-amino]-N-(5-methyl-[1,3,4]thiadiazol-2-yl)-benzenesulfonamide
107090-15-3

4-[(1H-Benzoimidazol-2-ylmethyl)-amino]-N-(5-methyl-[1,3,4]thiadiazol-2-yl)-benzenesulfonamide

Conditions
ConditionsYield
In methanol for 4h; Heating;81%
ethanol
64-17-5

ethanol

sulfamethizole
144-82-1

sulfamethizole

3-Formylchromone
17422-74-1

3-Formylchromone

4-{[(2-ethoxy-4-oxo-2H-chromen-3(4H)ylidene)methyl]amino}-N-(5-methyl-1,3,4-thiadiazol-2-yl)benzenesulfonamide
1449215-86-4

4-{[(2-ethoxy-4-oxo-2H-chromen-3(4H)ylidene)methyl]amino}-N-(5-methyl-1,3,4-thiadiazol-2-yl)benzenesulfonamide

Conditions
ConditionsYield
With toluene-4-sulfonic acid Heating;81%
sulfamethizole
144-82-1

sulfamethizole

2-hydroxynaphthalene-1-carbaldehyde
708-06-5

2-hydroxynaphthalene-1-carbaldehyde

4-{(E)-[(2-hydroxynaphthalen-1-yl)methylidene]amino}-N-(5-methyl-1,3,4-thiadiazol-2-yl)benzenesulfonamide

4-{(E)-[(2-hydroxynaphthalen-1-yl)methylidene]amino}-N-(5-methyl-1,3,4-thiadiazol-2-yl)benzenesulfonamide

Conditions
ConditionsYield
With toluene-4-sulfonic acid In ethanol for 6h; Reflux;81%
sulfamethizole
144-82-1

sulfamethizole

2-Chloromethyl-4(7)-nitro-benzimidazole
99876-68-3

2-Chloromethyl-4(7)-nitro-benzimidazole

N-(5-Methyl-[1,3,4]thiadiazol-2-yl)-4-[(4-nitro-1H-benzoimidazol-2-ylmethyl)-amino]-benzenesulfonamide
107090-22-2

N-(5-Methyl-[1,3,4]thiadiazol-2-yl)-4-[(4-nitro-1H-benzoimidazol-2-ylmethyl)-amino]-benzenesulfonamide

Conditions
ConditionsYield
In methanol for 4h; Heating;80%
sulfamethizole
144-82-1

sulfamethizole

methyl 3-formyl-5-(6-methoxypyridin-3-yl)benzoate

methyl 3-formyl-5-(6-methoxypyridin-3-yl)benzoate

methyl 3-(6-methoxypyridin-3-yl)-5-((4-(N-(5-methyl-1,3,4-thiadiazol-2-yl)sulfamoyl)phenylamino)methyl)benzoate

methyl 3-(6-methoxypyridin-3-yl)-5-((4-(N-(5-methyl-1,3,4-thiadiazol-2-yl)sulfamoyl)phenylamino)methyl)benzoate

Conditions
ConditionsYield
With sodium tris(acetoxy)borohydride; acetic acid In dichloromethane at 20℃;80%
4-chloro-2-phenylquinazoline
6484-25-9

4-chloro-2-phenylquinazoline

sulfamethizole
144-82-1

sulfamethizole

N-(5-methyl-1,3,4-thiadiazol-2-yl)-4-(2-phenylquinazolin-4-ylamino)benzenesulfonamide

N-(5-methyl-1,3,4-thiadiazol-2-yl)-4-(2-phenylquinazolin-4-ylamino)benzenesulfonamide

Conditions
ConditionsYield
In N,N-dimethyl-formamide for 22h; Reflux;80%
sulfamethizole
144-82-1

sulfamethizole

(E)-3-(N,N-dimethylamino)-1-(3,4-dimethoxyphenyl)-2-propen-1-one
127172-22-9

(E)-3-(N,N-dimethylamino)-1-(3,4-dimethoxyphenyl)-2-propen-1-one

Z-4-(3-(3,4-dimethoxyphenyl)-3-oxoprop-1-enylamino)-N-(5-methyl-1,3,4-thiadiazol-2-yl)benzenesulfonamide

Z-4-(3-(3,4-dimethoxyphenyl)-3-oxoprop-1-enylamino)-N-(5-methyl-1,3,4-thiadiazol-2-yl)benzenesulfonamide

Conditions
ConditionsYield
With acetic acid In ethanol for 22h; Reflux;80%
sulfamethizole
144-82-1

sulfamethizole

N-allyl isothiocyanate
57-06-7

N-allyl isothiocyanate

C13H15N5O2S3

C13H15N5O2S3

Conditions
ConditionsYield
In butan-1-ol Heating;79%
sulfamethizole
144-82-1

sulfamethizole

methyl iodide
74-88-4

methyl iodide

(Z)-N-(3,5-dimethyl-1,3,4-thiadiazol-2(3H)-ylidene)-4-(dimethylamino)benzenesulfonamide

(Z)-N-(3,5-dimethyl-1,3,4-thiadiazol-2(3H)-ylidene)-4-(dimethylamino)benzenesulfonamide

Conditions
ConditionsYield
In N,N-dimethyl-formamide at 20℃; for 24h;79%
formaldehyd
50-00-0

formaldehyd

sulfamethizole
144-82-1

sulfamethizole

N-(4-carbamoylphenyl)nicotinamide
418790-13-3

N-(4-carbamoylphenyl)nicotinamide

N-[4-({[4-(5-methyl-[1,3,4]thiadiazol-2-ylsulfamoyl)-phenylamino]-methyl}-carbamoyl)-phenyl]-nicotinamide

N-[4-({[4-(5-methyl-[1,3,4]thiadiazol-2-ylsulfamoyl)-phenylamino]-methyl}-carbamoyl)-phenyl]-nicotinamide

Conditions
ConditionsYield
Stage #1: formaldehyd; N-(4-carbamoyl-phenyl)-nicotinamide With hydrogenchloride In methanol at 0℃; for 0.5h; pH=3.5;
Stage #2: sulfamethizole Heating;
78%
sulfamethizole
144-82-1

sulfamethizole

((E)-3-(3-(dimethylamino)acryloyl))-2H-chromen-2-one
371756-61-5

((E)-3-(3-(dimethylamino)acryloyl))-2H-chromen-2-one

(Z)-N-(5-methyl-1,3,4-thiadiazol-2-yl)-4-(3-oxo-3-(2-oxo-2H-chromen-3-yl)prop-1-enylamino)benzenesulfonamide

(Z)-N-(5-methyl-1,3,4-thiadiazol-2-yl)-4-(3-oxo-3-(2-oxo-2H-chromen-3-yl)prop-1-enylamino)benzenesulfonamide

Conditions
ConditionsYield
In ethanol for 21h; Reflux;77%
sulfamethizole
144-82-1

sulfamethizole

(Z)-3-(dimethylamino)-1-(10H-phenothiazin-2-yl)prop-2-en-1-one

(Z)-3-(dimethylamino)-1-(10H-phenothiazin-2-yl)prop-2-en-1-one

(Z)-N-(5-methyl-1,3,4-thiadiazol-2-yl)-4-(3-oxo-3-(10H-phenothiazine-2yl)prop-1-enylamino)benzenesulfonamide

(Z)-N-(5-methyl-1,3,4-thiadiazol-2-yl)-4-(3-oxo-3-(10H-phenothiazine-2yl)prop-1-enylamino)benzenesulfonamide

Conditions
ConditionsYield
In ethanol for 18h; Reflux;77%
sulfamethizole
144-82-1

sulfamethizole

chloroacetyl chloride
79-04-9

chloroacetyl chloride

2-chloro-N-[4-(5-methyl-[1,3,4]thiadiazol-2-ylsulfamoyl)-phenyl]-acetamide
24694-13-1

2-chloro-N-[4-(5-methyl-[1,3,4]thiadiazol-2-ylsulfamoyl)-phenyl]-acetamide

Conditions
ConditionsYield
With triethylamine In acetone at 20℃; Cooling with ice;76%
2-(chloromethyl)-5-nitro-1H-benzo[d]imidazole
14625-39-9

2-(chloromethyl)-5-nitro-1H-benzo[d]imidazole

sulfamethizole
144-82-1

sulfamethizole

N-(5-Methyl-[1,3,4]thiadiazol-2-yl)-4-[(5-nitro-1H-benzoimidazol-2-ylmethyl)-amino]-benzenesulfonamide
107090-30-2

N-(5-Methyl-[1,3,4]thiadiazol-2-yl)-4-[(5-nitro-1H-benzoimidazol-2-ylmethyl)-amino]-benzenesulfonamide

Conditions
ConditionsYield
In methanol for 4h; Heating;73%
sulfamethizole
144-82-1

sulfamethizole

4-propyl-phenyl isothiocyanate
718604-99-0

4-propyl-phenyl isothiocyanate

N-(5-methyl-1,3,4-thiadiazol-2-yl)-4-{[(4-propylphenyl)carbamothioyl]amino}benzenesulfonamide

N-(5-methyl-1,3,4-thiadiazol-2-yl)-4-{[(4-propylphenyl)carbamothioyl]amino}benzenesulfonamide

Conditions
ConditionsYield
In acetone at 20 - 80℃; for 6.5h;70%
sulfamethizole
144-82-1

sulfamethizole

acetic anhydride
108-24-7

acetic anhydride

5-Bromo-2-aminobenzoic acid
5794-88-7

5-Bromo-2-aminobenzoic acid

4-(6-bromo-2-methyl-4-oxoquinazolin-3(4H)-yl)-N-(5-methyl-1,3,4-thiadiazol-2-yl)benzenesulfonamide

4-(6-bromo-2-methyl-4-oxoquinazolin-3(4H)-yl)-N-(5-methyl-1,3,4-thiadiazol-2-yl)benzenesulfonamide

Conditions
ConditionsYield
Stage #1: acetic anhydride; 5-Bromo-2-aminobenzoic acid for 4h; Reflux;
Stage #2: sulfamethizole With acetic acid for 4h; Reflux;
70%
sulfamethizole
144-82-1

sulfamethizole

acetic anhydride
108-24-7

acetic anhydride

5-chloroanthranilic acid
635-21-2

5-chloroanthranilic acid

4-(6-chloro-2-methyl-4-oxoquinazolin-3(4H)-yl)-N-(5-methyl-1,3,4-thiadiazol-2-yl)benzenesulfonamide

4-(6-chloro-2-methyl-4-oxoquinazolin-3(4H)-yl)-N-(5-methyl-1,3,4-thiadiazol-2-yl)benzenesulfonamide

Conditions
ConditionsYield
Stage #1: acetic anhydride; 5-chloroanthranilic acid for 4h; Reflux;
Stage #2: sulfamethizole With acetic acid for 4h; Reflux;
69%
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