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Sinoway Industrial Co., Ltd.

Why is SINOWAY: 1) Specialized in pharmaceutical and healthcare industrial for 34 years. 2) ISO 9001:2015 & SGS audited supplier . 3) Accept various payment terms : T.T 30-60 days. 4) We have warehouse in USA with quickly shipment . 5) We c

99% up by HPLC, GMP, JP Pitavastatin Calcium 147526-32-7

Cas:147526-32-7

Min.Order:1 Kilogram

FOB Price: $100.0

Type:Trading Company

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Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch

Pitavastatin calcium Manufacturer/High quality/Best price/In stock

Cas:147526-32-7

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Hangzhou Dingyan Chem Co., Ltd

Items Standard Result Assay 98%min ----------------------------------------------------------------------------------------------

High purity Various Specifications Pitavastatin calcium CAS:147526-32-7

Cas:147526-32-7

Min.Order:1 Gram

FOB Price: $100.0 / 500.0

Type:Manufacturers

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Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality Pitavastatin Calcium supplier in China

Cas:147526-32-7

Min.Order:0 Metric Ton

Negotiable

Type:Manufacturers

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Hebei yanxi chemical co.,LTD.

Hebei yanxi chemical co., LTD is a professional research, development and production 2-phenylacetamide enterprise backbone members by local well-known entrepreneurs and professional senior engineers in the party's "low carbon environ

Pitavastatin calcium in Bulk Supply

Cas:147526-32-7

Min.Order:100 Gram

FOB Price: $2.0

Type:Manufacturers

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Wuhan Fortuna Chemical Co.,Ltd

Unique advantages of Pitavastatin calcium Cas 147526-32-7 Guaranteed purity High quality & competitive price Quality control Fast feedback Prompt shipment Appearance:White to pale yellowish powder Storage:Cool dry place Package:100g

High quality Pitavastatin calcium Cas 147526-32-7 with best price and good service

Cas:147526-32-7

Min.Order:100 Gram

Negotiable

Type:Trading Company

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Hefei TNJ chemical industry co.,ltd

Service we can provide: 1. Mixed container: We can mix different items in one container. 2. Quality control: Before shipment, we can provide free sample for test. Inspection before shipping. 3. Packing: We can pack according to your requirem

Pitavastatin calcium

Cas:147526-32-7

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

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Henan Allgreen Chemical Co.,Ltd

high quality Appearance:Solid Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Intermediates Transportation:by air or by sea Port:Shanghai, Qingdao

Pitavastatin calcium 147526-32-7

Cas:147526-32-7

Min.Order:1 Kilogram

Negotiable

Type:Manufacturers

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply Pitavastatin Calcium

Cas:147526-32-7

Min.Order:1

Negotiable

Type:Other

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Kono Chem Co.,Ltd

The atorvastatin calcium. English Name: Calcium Pitavastatin Molecular weight: 880.98 147526-32-7 CAS: Uses: applicable to hyperlipidemia and high cholesterol. Quality standard: enterprise standard project standard Properties whit

Pitavastatin calcium in Bulk Supply

Cas:147526-32-7

Min.Order:1 Kilogram

FOB Price: $3000.0

Type:Other

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Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

Factory Price API 99% Pitavastatin calcium 147526-32-7 GMP Manufacturer

Cas:147526-32-7

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

Pitavastatin Calcium

Cas:147526-32-7

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

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Henan Tianfu Chemical Co., Ltd.

Product Name: Pitavastatin calcium Synonyms: 147526-32-7 Pitavastatin Calcium;Pitavastatin Calcuim;Pitavastatin calcium, >=98.5%;Pitavastatin (calcium salt);monocalciumbis[(3R,5S,6E)-7-(2-Cyclopropyl-4-(4-Fluorophenyl)-3-Quinolyl)-3,5-Dihydroxy

147526-32-7 Pitavastatin calcium

Cas:147526-32-7

Min.Order:1 Kilogram

FOB Price: $230.0

Type:Lab/Research institutions

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LIDE PHARMACEUTICALS LIMITED

LIDE PHARMACEUTICALS LIMITED is a professional chemicals and APIs leading manufacturer in China. Our core business line covers APIs, Intermediates, Herb extract, etc.

Pitavastatin calcium

Cas:147526-32-7

Min.Order:1 Kilogram

FOB Price: $0.9 / 1.0

Type:Lab/Research institutions

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Hebei Nengqian Chemical Import and Export Co., LTD

Our Advantage Rich Experience Our products are sold all over Europe,North&South America, Sino-East, Asia and pacific area as well as Africa,we establish long term. Quality service Company cooperates with research institutes. We strictly con

Pitavastatin calcium 147526-32-7

Cas:147526-32-7

Min.Order:1 Kilogram

FOB Price: $1.0 / 10.0

Type:Trading Company

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Pharmaceutical Grade CAS 147526-32-7 with competitive price

Cas:147526-32-7

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

Pivastatin calcium API 147526-32-7

Cas:147526-32-7

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

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Henan Sinotech Import&Export Corporation

147526-32-7 Pharmaceutical Powder Pitavastatin Calcium Treatment Coronary Heart Disease Physical and Chemical Properties Common Name Pitavastatin Calcium Chemical Name Mo

Pitavastatin calcium, 147526-32-7

Cas:147526-32-7

Min.Order:1 Metric Ton

FOB Price: $1.0

Type:Other

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Hebei Sankai Chemical Technology Co., Ltd

1. Product advantages ♦ High purity, all above 98.5%, no impurities after dissolution ♦ We will test each batch to ensure quality ♦ OEM and private brand services designed for free ♦ Various cap colors available ♦ W

Pitavastatin calcium CAS:147526-32-7

Cas:147526-32-7

Min.Order:1 Kilogram

FOB Price: $38.0 / 59.0

Type:Trading Company

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Shijiazhuang Sdyano Fine Chemical Co., Ltd

1. Best prices with satisfied quality; 2. It's clients' right to choose the package's Courier (EMS, DHL, FedEx, UPS); 3.It's clients' right to choose the packing way for his produccts from many recent effective packing ways;

Pitavastatin calcium

Cas:147526-32-7

Min.Order:0 Metric Ton

Negotiable

Type:Trading Company

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Hubei Langyou International Trading Co., Ltd

1. Guaranteed purity; 2. Large quantity in stock; 3. Largest manufacturer; 4. Best service after shipment with email; 5. High quality & competitive price; Appearance:A white or pale yellow powder Storage:Store in sealed contai

HANWAYS CHEMPHARM CO.,LIMITED

Hanways chempharm is a specialized company concentrating on the R&D, production, marketing and technical service of APIs and pharmaceutical intermediates. The marketing department is located in Wuhan. We have two GMP facilities in Hubei Pr

Top Quality Pitavastatin Calcium CAS 147526-32-7 Livalo for Lipid-Lowering

Cas:147526-32-7

Min.Order:1 Kilogram

FOB Price: $200.0 / 400.0

Type:Trading Company

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Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

Pitavastatin calcium 147526-32-7

Cas:147526-32-7

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Xi'an Faithful Biotech Co., Ltd.

We are the manufacturers and suppliers of API in China, and warehouse in Germany and USA of California, which can quickly and safely deliver to your address 1.High quality and competitive price. 2.Free sample for your evaluation. 3.Promptly delivery

Chemical Powder Pitavastatin Calcium Raw Material Powder Pitavastatin Calcium

Cas:147526-32-7

Min.Order:10 Gram

FOB Price: $3.5

Type:Trading Company

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Shanghai Minstar Chemical Co., Ltd

Product Name: Pitavastatin calcium CAS: 147526-32-7 MF: C25H26CaFNO4 MW: 463.56 EINECS: 807-641-2 Mol File: 147526-32-7.mol Pitavastatin calcium Structure Pitavastatin calcium Chemical Properties alpha D20 +23.1° (c = 1.00

Pitavastatin calcium

Cas:147526-32-7

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Leader Biochemical Group

About Product Details Items Specifications Test Results Appearance White to white crystalline powde

Supply High Quality Pitavastatin Calcium CAS 147526-32-7 For research Use only

Cas:147526-32-7

Min.Order:1 Gram

FOB Price: $1.0 / 2.0

Type:Lab/Research institutions

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Hangzhou JINLAN Pharm-Drugs Technology Co., Ltd

We can provide GMP validation service that complies with SFDA, FDA, WHO and EU EMPA.Excellent registration team could help us easlily to register our products in different countries.If you and your customer are interested in some products or need C

pitavastatin calcium manufacturer with low price

Cas:147526-32-7

Min.Order:1 Gram

Negotiable

Type:Trading Company

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Baoji Guokang Healthchem co.,ltd

Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At present

Statin lipid-lowering drugs Pitavastatin calcium/CAS:147526-32-7

Cas:147526-32-7

Min.Order:1 Kilogram

FOB Price: $2131.0 / 2421.9

Type:Trading Company

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Qingdao Beluga Import and Export Co., LTD

Beluga chemical professional supply High quality Pitavastatin calcium CAS 147526-32-7 1. Beluga Chemical has a professional RESEARCH and development team and strong technical force to ensure technical support and research capabilities. 2. Made in

High quality Pitavastatin calcium CAS 147526-32-7

Cas:147526-32-7

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Shanghai Terui OP New Material Technology Co., Ltd.

We have overseas warehouses in California, New Laredo Mexico, Vancouver Canada, Amsterdam Netherlands, and Melbourne Australia. Overseas warehouses can provide some of the best-selling products. We look forward to the cooperation of local powerful d

cas 147526-32-7 Pitavastatin calcium Chinese manufacturer

Cas:147526-32-7

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

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Synthetic route

methyl (3R,5S,6E)-7-{2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl}-3,5-dihydroxyhept-6-enoate
849811-78-5

methyl (3R,5S,6E)-7-{2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl}-3,5-dihydroxyhept-6-enoate

pitavastatin
147526-32-7

pitavastatin

Conditions
ConditionsYield
With sodium hydroxide In methanol at 20℃; for 0.5h;100%
With water; sodium hydroxide In methanol at 20℃; for 2h; Product distribution / selectivity;
pitavastatin calcium salt
147526-32-7

pitavastatin calcium salt

pitavastatin
147526-32-7

pitavastatin

Conditions
ConditionsYield
With hydrogenchloride In water; ethyl acetate at 25 - 35℃;95.9%
With hydrogenchloride In dichloromethane; water at 0 - 25℃; for 0.833333h; pH=3;
With hydrogenchloride In water; ethyl acetate pH=4;3.7 g
With hydrogenchloride In dichloromethane; water
(4R,6S)-(E)-{6-[2-(2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)-vinyl]-2,2-dimethyl-1,3-dioxan-4-yl}acetic acid tert-butyl ester
147489-06-3

(4R,6S)-(E)-{6-[2-(2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)-vinyl]-2,2-dimethyl-1,3-dioxan-4-yl}acetic acid tert-butyl ester

pitavastatin
147526-32-7

pitavastatin

Conditions
ConditionsYield
Stage #1: (4R,6S)-(E)-{6-[2-(2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)-vinyl]-2,2-dimethyl-1,3-dioxan-4-yl}acetic acid tert-butyl ester With trifluoroacetic acid In acetonitrile at 30 - 35℃;
Stage #2: With caesium carbonate In acetonitrile at 35 - 40℃;
94%
Multi-step reaction with 3 steps
1.1: water; oxalic acid / methanol / 6 h / 35 °C
1.2: 2.75 h / 10 - 30 °C / pH 7
2.1: sodium hydroxide; water / methanol / 1.67 h / 0 °C
2.2: 0.67 h / 25 °C
3.1: hydrogenchloride / dichloromethane; water / 0.83 h / 0 - 25 °C / pH 3
View Scheme
Multi-step reaction with 4 steps
1.1: water; oxalic acid / methanol / 6 h / 35 °C
1.2: 2.75 h / 10 - 30 °C / pH 7
2.1: sodium hydroxide; water / acetonitrile / 1.5 h / 30 °C
2.2: 0.25 h / 0 °C / pH 4
2.3: 0.5 h / 0 °C
3.1: sodium hydroxide / water / 0.75 h / 30 °C
3.2: 0.75 h / 35 °C
4.1: hydrogenchloride / dichloromethane; water / 0.83 h / 0 - 25 °C / pH 3
View Scheme
Multi-step reaction with 2 steps
1: hydrogenchloride / acetonitrile; water / 2 h / 13 °C
2: sodium hydroxide / water / 2 h / 10 °C / Large scale
View Scheme
(E)-(3R,5S)-7-[2-cyclopropyl-4-(4-fluoro-phenyl)-quinolin-3-yl]-3,5-dihydroxy-hept-6-enoic acid ethyl ester
167073-19-0

(E)-(3R,5S)-7-[2-cyclopropyl-4-(4-fluoro-phenyl)-quinolin-3-yl]-3,5-dihydroxy-hept-6-enoic acid ethyl ester

pitavastatin
147526-32-7

pitavastatin

Conditions
ConditionsYield
With ethanol; sodium hydroxide In water at 20℃; for 3h;87.4%
(3R,5S,6E)-7-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolyl]-3,5-dihydroxy-6-heptenoic acid tert-butyl ester
586966-54-3

(3R,5S,6E)-7-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolyl]-3,5-dihydroxy-6-heptenoic acid tert-butyl ester

pitavastatin
147526-32-7

pitavastatin

Conditions
ConditionsYield
With sodium hydroxide In water at 10℃; for 2h; Large scale;83.9%
Stage #1: (3R,5S,6E)-7-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolyl]-3,5-dihydroxy-6-heptenoic acid tert-butyl ester With hydrogenchloride; water In methanol at 25℃; for 2.16667h;
Stage #2: With hydrogenchloride In dichloromethane at 0 - 25℃; for 0.916667h; pH=3;
Multi-step reaction with 2 steps
1.1: sodium hydroxide; water / methanol / 1.67 h / 0 °C
1.2: 0.67 h / 25 °C
2.1: hydrogenchloride / dichloromethane; water / 0.83 h / 0 - 25 °C / pH 3
View Scheme
Multi-step reaction with 3 steps
1.1: sodium hydroxide; water / acetonitrile / 1.5 h / 30 °C
1.2: 0.25 h / 0 °C / pH 4
1.3: 0.5 h / 0 °C
2.1: sodium hydroxide / water / 0.75 h / 30 °C
2.2: 0.75 h / 35 °C
3.1: hydrogenchloride / dichloromethane; water / 0.83 h / 0 - 25 °C / pH 3
View Scheme
(4R)-4,7,7-trimethyl-3-exo-(1-naphthyl)bicyclo<2.2.1>heptan-2-exo-yl (3R,5S,6E)-7-<2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl>-3,5-dihydroxy-6-heptenoate

(4R)-4,7,7-trimethyl-3-exo-(1-naphthyl)bicyclo<2.2.1>heptan-2-exo-yl (3R,5S,6E)-7-<2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl>-3,5-dihydroxy-6-heptenoate

pitavastatin
147526-32-7

pitavastatin

Conditions
ConditionsYield
With sodium hydroxide In methanol for 12h; Ambient temperature;
(±)-E-3,5-dihydroxy-7-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolyl]-6-heptenoic acid ethyl ester

(±)-E-3,5-dihydroxy-7-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolyl]-6-heptenoic acid ethyl ester

pitavastatin
147526-32-7

pitavastatin

Conditions
ConditionsYield
Stage #1: (±)-E-3,5-dihydroxy-7-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolyl]-6-heptenoic acid ethyl ester With sodium hydroxide Hydrolysis;
Stage #2: With (+)-1-phenylethylamine resolution;
(3R,5S,6E)-7-[2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]-3,5-dihydroxy-[(1S)-1-phenylethyl]hept-6-enamide

(3R,5S,6E)-7-[2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]-3,5-dihydroxy-[(1S)-1-phenylethyl]hept-6-enamide

pitavastatin
147526-32-7

pitavastatin

Conditions
ConditionsYield
Stage #1: (3R,5S,6E)-7-[2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]-3,5-dihydroxy-[(1S)-1-phenylethyl]hept-6-enamide With sodium hydroxide In ethanol at 50 - 55℃; for 26h;
Stage #2: With hydrogenchloride In ethyl acetate Further stages.;
2-cyclopropyl-4-(4-fluorophenyl)-3-(hydroxymethyl)quinoline
121660-11-5

2-cyclopropyl-4-(4-fluorophenyl)-3-(hydroxymethyl)quinoline

pitavastatin
147526-32-7

pitavastatin

Conditions
ConditionsYield
Multi-step reaction with 6 steps
1.1: DMSO; P2O5; Et3N
2.1: NaOH; (n-octyl)3MeNCl / toluene; H2O
3.1: DIBAH
4.1: NaH; n-BuLi
5.1: NaBH4; Et2BOMe / -78 °C
6.1: aq. NaOH
6.2: (+)-α-methylbenzylamine
View Scheme
Multi-step reaction with 4 steps
1.1: phosphorus tribromide / dichloromethane / 1.5 h / 25 °C
1.2: 1 h / 75 °C
2.1: potassium carbonate / dimethyl sulfoxide / 7 h / 75 °C
3.1: water; oxalic acid / methanol / 6 h / 35 °C
3.2: 2.75 h / 10 - 30 °C / pH 7
4.1: hydrogenchloride; water / methanol / 2.17 h / 25 °C
4.2: 0.92 h / 0 - 25 °C / pH 3
View Scheme
Multi-step reaction with 5 steps
1.1: phosphorus tribromide / dichloromethane / 1.5 h / 25 °C
1.2: 1 h / 75 °C
2.1: potassium carbonate / dimethyl sulfoxide / 7 h / 75 °C
3.1: water; oxalic acid / methanol / 6 h / 35 °C
3.2: 2.75 h / 10 - 30 °C / pH 7
4.1: sodium hydroxide; water / methanol / 1.67 h / 0 °C
4.2: 0.67 h / 25 °C
5.1: hydrogenchloride / dichloromethane; water / 0.83 h / 0 - 25 °C / pH 3
View Scheme
Multi-step reaction with 6 steps
1.1: phosphorus tribromide / dichloromethane / 1.5 h / 25 °C
1.2: 1 h / 75 °C
2.1: potassium carbonate / dimethyl sulfoxide / 7 h / 75 °C
3.1: water; oxalic acid / methanol / 6 h / 35 °C
3.2: 2.75 h / 10 - 30 °C / pH 7
4.1: sodium hydroxide; water / acetonitrile / 1.5 h / 30 °C
4.2: 0.25 h / 0 °C / pH 4
4.3: 0.5 h / 0 °C
5.1: sodium hydroxide / water / 0.75 h / 30 °C
5.2: 0.75 h / 35 °C
6.1: hydrogenchloride / dichloromethane; water / 0.83 h / 0 - 25 °C / pH 3
View Scheme
Multi-step reaction with 5 steps
1: thionyl chloride / toluene; dichloromethane / 15 °C
2: toluene / 12 h / Reflux; Large scale
3: potassium carbonate / dimethyl sulfoxide / 3 h / 30 - 50 °C / Large scale
4: hydrogenchloride / acetonitrile; water / 2 h / 13 °C
5: sodium hydroxide / water / 2 h / 10 °C / Large scale
View Scheme
2-cyclopropyl-4-(4-fluorophenyl)-3-formylquinoline
121660-37-5

2-cyclopropyl-4-(4-fluorophenyl)-3-formylquinoline

pitavastatin
147526-32-7

pitavastatin

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1.1: NaOH; (n-octyl)3MeNCl / toluene; H2O
2.1: DIBAH
3.1: NaH; n-BuLi
4.1: NaBH4; Et2BOMe / -78 °C
5.1: aq. NaOH
5.2: (+)-α-methylbenzylamine
View Scheme
Multi-step reaction with 3 steps
1.1: sodium t-butanolate / 1-methyl-pyrrolidin-2-one; 2-methyltetrahydrofuran; tetrahydrofuran / -60 - 22 °C
2.1: hydrogenchloride / acetonitrile; water / 1.5 h / 45 °C
2.2: 1.5 h
3.1: hydrogenchloride / water; ethyl acetate / pH 4
View Scheme
Multi-step reaction with 4 steps
1.1: sodium t-butanolate / 1-methyl-pyrrolidin-2-one; 2-methyltetrahydrofuran; tetrahydrofuran / -60 - 22 °C
2.1: hydrogenchloride / acetonitrile; water / 2.5 h / 45 °C
2.2: 1.5 h / 10 °C
3.1: sodium hydroxide / water / pH 12.3
3.2: 1.25 h / pH 9.7
4.1: hydrogenchloride / water; ethyl acetate / pH 4
View Scheme
(E)-3-[2-cyclopropyl-4-(4-fluoro-phenyl)-quinolin-3-yl]-propenal
148901-68-2

(E)-3-[2-cyclopropyl-4-(4-fluoro-phenyl)-quinolin-3-yl]-propenal

pitavastatin
147526-32-7

pitavastatin

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: NaH; n-BuLi
2.1: NaBH4; Et2BOMe / -78 °C
3.1: aq. NaOH
3.2: (+)-α-methylbenzylamine
View Scheme
(E)-3-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-2-propenenitrile
256431-72-8

(E)-3-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-2-propenenitrile

pitavastatin
147526-32-7

pitavastatin

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: DIBAH
2.1: NaH; n-BuLi
3.1: NaBH4; Et2BOMe / -78 °C
4.1: aq. NaOH
4.2: (+)-α-methylbenzylamine
View Scheme
(E)-7-[2-cyclopropyl-4-(4-fluorophenyl)-quinolin-3-yl]-5-hydroxy-3-oxohept-6-enic acid ethyl ester
148901-69-3

(E)-7-[2-cyclopropyl-4-(4-fluorophenyl)-quinolin-3-yl]-5-hydroxy-3-oxohept-6-enic acid ethyl ester

pitavastatin
147526-32-7

pitavastatin

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: NaBH4; Et2BOMe / -78 °C
2.1: aq. NaOH
2.2: (+)-α-methylbenzylamine
View Scheme
With Candida rugosa IFO0591 In dimethyl sulfoxide at 30℃; for 20h; pH=7; Product distribution / selectivity; Aerobic conditions; potassium phosphate buffer (pH 7.0);n/a
With Candida molischiana IFO10296 In dimethyl sulfoxide at 30℃; for 20h; pH=7; Product distribution / selectivity; Aerobic conditions; potassium phosphate buffer (pH 7.0);n/a
(E)-7-[2-cyclopropyl-4-(4-fluoro-phenyl)-quinolin-3-yl]-3,5-dioxo-hept-6-enoic acid ethyl ester
166803-31-2

(E)-7-[2-cyclopropyl-4-(4-fluoro-phenyl)-quinolin-3-yl]-3,5-dioxo-hept-6-enoic acid ethyl ester

pitavastatin
147526-32-7

pitavastatin

Conditions
ConditionsYield
With Candida famata RIFY7455 In dimethyl sulfoxide at 30℃; for 20h; pH=7; Product distribution / selectivity; Aerobic conditions; potassium phosphate buffer (pH 7.0);n/a
With Candida albicans IFO1594 In dimethyl sulfoxide at 30℃; for 20h; pH=7; Product distribution / selectivity; Aerobic conditions; potassium phosphate buffer (pH 7.0);n/a
With Candida parapsilosis CBS604 In dimethyl sulfoxide at 30℃; for 20h; pH=7; Product distribution / selectivity; Aerobic conditions; potassium phosphate buffer (pH 7.0);n/a
(R)-1-benzyl 7-methyl 5-(tert-butyldimethylsilyloxy)-3-oxoheptanedioate
1343494-43-8

(R)-1-benzyl 7-methyl 5-(tert-butyldimethylsilyloxy)-3-oxoheptanedioate

pitavastatin
147526-32-7

pitavastatin

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1.1: hydrogen / palladium 10% on activated carbon / ethyl acetate / 2 h / 20 °C / Inert atmosphere
2.1: piperidine / N,N-dimethyl-formamide / 10.25 h / 20 - 40 °C / Inert atmosphere
3.1: hydrogenchloride / water; methanol / 0 - 20 °C
4.1: sodium tetrahydroborate; diethyl methoxy borane / tetrahydrofuran; methanol / 0.5 h / -78 °C
4.2: 1 h / 50 °C
5.1: sodium hydroxide; water / methanol / 2 h / 20 °C
View Scheme
(R)-5-(tert-butyldimethylsilyloxy)-7-methoxy-3,7-dioxoheptanoic acid
1343494-44-9

(R)-5-(tert-butyldimethylsilyloxy)-7-methoxy-3,7-dioxoheptanoic acid

pitavastatin
147526-32-7

pitavastatin

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: piperidine / N,N-dimethyl-formamide / 10.25 h / 20 - 40 °C / Inert atmosphere
2.1: hydrogenchloride / water; methanol / 0 - 20 °C
3.1: sodium tetrahydroborate; diethyl methoxy borane / tetrahydrofuran; methanol / 0.5 h / -78 °C
3.2: 1 h / 50 °C
4.1: sodium hydroxide; water / methanol / 2 h / 20 °C
View Scheme
(R,E)-methyl 3-(tert-butyldimethylsilyloxy)-7-(2-cyclopropyl-4-(-4-fluorophenyl)-quinolin-3-yl)-5-oxohept-6-enoate

(R,E)-methyl 3-(tert-butyldimethylsilyloxy)-7-(2-cyclopropyl-4-(-4-fluorophenyl)-quinolin-3-yl)-5-oxohept-6-enoate

pitavastatin
147526-32-7

pitavastatin

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: hydrogenchloride / water; methanol / 0 - 20 °C
2.1: sodium tetrahydroborate; diethyl methoxy borane / tetrahydrofuran; methanol / 0.5 h / -78 °C
2.2: 1 h / 50 °C
3.1: sodium hydroxide; water / methanol / 2 h / 20 °C
View Scheme
Cyclopropyl methyl ketone
765-43-5

Cyclopropyl methyl ketone

pitavastatin
147526-32-7

pitavastatin

Conditions
ConditionsYield
Multi-step reaction with 6 steps
1.1: toluene / 0.25 h / 25 °C
1.2: 14 h / 10 - 75 °C / Inert atmosphere
1.3: 0.75 h / 0 - 25 °C / pH 2.5
2.1: sulfuric acid / water; methanol / 22.25 h / 25 - 65 °C
2.2: 0.75 h / 0 - 25 °C / pH 6
3.1: toluene / 5 h / 25 °C / Inert atmosphere
3.2: 3 h
3.3: 2 h / 40 °C
4.1: potassium carbonate / dimethyl sulfoxide / 7 h / 75 °C
5.1: water; oxalic acid / methanol / 6 h / 35 °C
5.2: 2.75 h / 10 - 30 °C / pH 7
6.1: hydrogenchloride; water / methanol / 2.17 h / 25 °C
6.2: 0.92 h / 0 - 25 °C / pH 3
View Scheme
Multi-step reaction with 7 steps
1.1: toluene / 0.25 h / 25 °C
1.2: 14 h / 10 - 75 °C / Inert atmosphere
1.3: 0.75 h / 0 - 25 °C / pH 2.5
2.1: sulfuric acid / water; methanol / 22.25 h / 25 - 65 °C
2.2: 0.75 h / 0 - 25 °C / pH 6
3.1: toluene / 5 h / 25 °C / Inert atmosphere
3.2: 3 h
3.3: 2 h / 40 °C
4.1: potassium carbonate / dimethyl sulfoxide / 7 h / 75 °C
5.1: water; oxalic acid / methanol / 6 h / 35 °C
5.2: 2.75 h / 10 - 30 °C / pH 7
6.1: sodium hydroxide; water / methanol / 1.67 h / 0 °C
6.2: 0.67 h / 25 °C
7.1: hydrogenchloride / dichloromethane; water / 0.83 h / 0 - 25 °C / pH 3
View Scheme
Multi-step reaction with 7 steps
1.1: toluene / 0.25 h / 25 °C
1.2: 14 h / 10 - 75 °C / Inert atmosphere
1.3: 0.75 h / 0 - 25 °C / pH 2.5
2.1: sulfuric acid / water; methanol / 22.25 h / 25 - 65 °C
2.2: 0.75 h / 0 - 25 °C / pH 6
3.1: diisobutylaluminium hydride / toluene / 2 h / 0 - 25 °C
3.2: 0.25 h / 10 °C
4.1: phosphorus tribromide / dichloromethane / 1.5 h / 25 °C
4.2: 1 h / 75 °C
5.1: potassium carbonate / dimethyl sulfoxide / 7 h / 75 °C
6.1: water; oxalic acid / methanol / 6 h / 35 °C
6.2: 2.75 h / 10 - 30 °C / pH 7
7.1: hydrogenchloride; water / methanol / 2.17 h / 25 °C
7.2: 0.92 h / 0 - 25 °C / pH 3
View Scheme
methyl 3-cyclopropyl-3-oxopropanoate
32249-35-7

methyl 3-cyclopropyl-3-oxopropanoate

pitavastatin
147526-32-7

pitavastatin

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1.1: sulfuric acid / water; methanol / 22.25 h / 25 - 65 °C
1.2: 0.75 h / 0 - 25 °C / pH 6
2.1: toluene / 5 h / 25 °C / Inert atmosphere
2.2: 3 h
2.3: 2 h / 40 °C
3.1: potassium carbonate / dimethyl sulfoxide / 7 h / 75 °C
4.1: water; oxalic acid / methanol / 6 h / 35 °C
4.2: 2.75 h / 10 - 30 °C / pH 7
5.1: hydrogenchloride; water / methanol / 2.17 h / 25 °C
5.2: 0.92 h / 0 - 25 °C / pH 3
View Scheme
Multi-step reaction with 6 steps
1.1: sulfuric acid / water; methanol / 22.25 h / 25 - 65 °C
1.2: 0.75 h / 0 - 25 °C / pH 6
2.1: toluene / 5 h / 25 °C / Inert atmosphere
2.2: 3 h
2.3: 2 h / 40 °C
3.1: potassium carbonate / dimethyl sulfoxide / 7 h / 75 °C
4.1: water; oxalic acid / methanol / 6 h / 35 °C
4.2: 2.75 h / 10 - 30 °C / pH 7
5.1: sodium hydroxide; water / methanol / 1.67 h / 0 °C
5.2: 0.67 h / 25 °C
6.1: hydrogenchloride / dichloromethane; water / 0.83 h / 0 - 25 °C / pH 3
View Scheme
Multi-step reaction with 6 steps
1.1: sulfuric acid / water; methanol / 22.25 h / 25 - 65 °C
1.2: 0.75 h / 0 - 25 °C / pH 6
2.1: diisobutylaluminium hydride / toluene / 2 h / 0 - 25 °C
2.2: 0.25 h / 10 °C
3.1: phosphorus tribromide / dichloromethane / 1.5 h / 25 °C
3.2: 1 h / 75 °C
4.1: potassium carbonate / dimethyl sulfoxide / 7 h / 75 °C
5.1: water; oxalic acid / methanol / 6 h / 35 °C
5.2: 2.75 h / 10 - 30 °C / pH 7
6.1: hydrogenchloride; water / methanol / 2.17 h / 25 °C
6.2: 0.92 h / 0 - 25 °C / pH 3
View Scheme
methyl 4-(4'-fluorophenyl)-2-cyclopropylquinoline-3-carboxylate
121659-86-7

methyl 4-(4'-fluorophenyl)-2-cyclopropylquinoline-3-carboxylate

pitavastatin
147526-32-7

pitavastatin

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: toluene / 5 h / 25 °C / Inert atmosphere
1.2: 3 h
1.3: 2 h / 40 °C
2.1: potassium carbonate / dimethyl sulfoxide / 7 h / 75 °C
3.1: water; oxalic acid / methanol / 6 h / 35 °C
3.2: 2.75 h / 10 - 30 °C / pH 7
4.1: hydrogenchloride; water / methanol / 2.17 h / 25 °C
4.2: 0.92 h / 0 - 25 °C / pH 3
View Scheme
Multi-step reaction with 5 steps
1.1: toluene / 5 h / 25 °C / Inert atmosphere
1.2: 3 h
1.3: 2 h / 40 °C
2.1: potassium carbonate / dimethyl sulfoxide / 7 h / 75 °C
3.1: water; oxalic acid / methanol / 6 h / 35 °C
3.2: 2.75 h / 10 - 30 °C / pH 7
4.1: sodium hydroxide; water / methanol / 1.67 h / 0 °C
4.2: 0.67 h / 25 °C
5.1: hydrogenchloride / dichloromethane; water / 0.83 h / 0 - 25 °C / pH 3
View Scheme
Multi-step reaction with 5 steps
1.1: diisobutylaluminium hydride / toluene / 2 h / 0 - 25 °C
1.2: 0.25 h / 10 °C
2.1: phosphorus tribromide / dichloromethane / 1.5 h / 25 °C
2.2: 1 h / 75 °C
3.1: potassium carbonate / dimethyl sulfoxide / 7 h / 75 °C
4.1: water; oxalic acid / methanol / 6 h / 35 °C
4.2: 2.75 h / 10 - 30 °C / pH 7
5.1: hydrogenchloride; water / methanol / 2.17 h / 25 °C
5.2: 0.92 h / 0 - 25 °C / pH 3
View Scheme
pitavastatin methyl amine salt

pitavastatin methyl amine salt

pitavastatin
147526-32-7

pitavastatin

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: sodium hydroxide / water / 0.75 h / 30 °C
1.2: 0.75 h / 35 °C
2.1: hydrogenchloride / dichloromethane; water / 0.83 h / 0 - 25 °C / pH 3
View Scheme
<2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl>methyltriphenylphosphonium bromide

<2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl>methyltriphenylphosphonium bromide

pitavastatin
147526-32-7

pitavastatin

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: potassium carbonate / dimethyl sulfoxide / 7 h / 75 °C
2.1: water; oxalic acid / methanol / 6 h / 35 °C
2.2: 2.75 h / 10 - 30 °C / pH 7
3.1: hydrogenchloride; water / methanol / 2.17 h / 25 °C
3.2: 0.92 h / 0 - 25 °C / pH 3
View Scheme
Multi-step reaction with 4 steps
1.1: potassium carbonate / dimethyl sulfoxide / 7 h / 75 °C
2.1: water; oxalic acid / methanol / 6 h / 35 °C
2.2: 2.75 h / 10 - 30 °C / pH 7
3.1: sodium hydroxide; water / methanol / 1.67 h / 0 °C
3.2: 0.67 h / 25 °C
4.1: hydrogenchloride / dichloromethane; water / 0.83 h / 0 - 25 °C / pH 3
View Scheme
Multi-step reaction with 5 steps
1.1: potassium carbonate / dimethyl sulfoxide / 7 h / 75 °C
2.1: water; oxalic acid / methanol / 6 h / 35 °C
2.2: 2.75 h / 10 - 30 °C / pH 7
3.1: sodium hydroxide; water / acetonitrile / 1.5 h / 30 °C
3.2: 0.25 h / 0 °C / pH 4
3.3: 0.5 h / 0 °C
4.1: sodium hydroxide / water / 0.75 h / 30 °C
4.2: 0.75 h / 35 °C
5.1: hydrogenchloride / dichloromethane; water / 0.83 h / 0 - 25 °C / pH 3
View Scheme
(E)-3(R)-5(S)-dihydroxy-7-[4'-(4-fluorophenyl)-2'-cyclopropylquinoline-3'-yl]hept-6-eneacidD(+)phenylethylamine salt
1392469-74-7

(E)-3(R)-5(S)-dihydroxy-7-[4'-(4-fluorophenyl)-2'-cyclopropylquinoline-3'-yl]hept-6-eneacidD(+)phenylethylamine salt

pitavastatin
147526-32-7

pitavastatin

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: sodium hydroxide; calcium chloride / water
2: hydrogenchloride / dichloromethane; water / 0.83 h / 0 - 25 °C / pH 3
View Scheme
2-((4R,6S)-6-((E)-2-(2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)vinyl)-2,2-dimethyl-1 ,3-dioxan-4-yl)acetate methyl ester

2-((4R,6S)-6-((E)-2-(2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)vinyl)-2,2-dimethyl-1 ,3-dioxan-4-yl)acetate methyl ester

pitavastatin
147526-32-7

pitavastatin

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: hydrogenchloride / acetonitrile; water / 1.5 h / 45 °C
1.2: 1.5 h
2.1: hydrogenchloride / water; ethyl acetate / pH 4
View Scheme
Multi-step reaction with 3 steps
1.1: hydrogenchloride / acetonitrile; water / 2.5 h / 45 °C
1.2: 1.5 h / 10 °C
2.1: sodium hydroxide / water / pH 12.3
2.2: 1.25 h / pH 9.7
3.1: hydrogenchloride / water; ethyl acetate / pH 4
View Scheme
2-((4R,6S)-6-((benzo[d]thiazol-2-ylsulfonyl)methyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetic acid methyl ester
1388627-65-3

2-((4R,6S)-6-((benzo[d]thiazol-2-ylsulfonyl)methyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetic acid methyl ester

pitavastatin
147526-32-7

pitavastatin

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: sodium t-butanolate / 1-methyl-pyrrolidin-2-one; 2-methyltetrahydrofuran; tetrahydrofuran / -60 - 22 °C
2.1: hydrogenchloride / acetonitrile; water / 1.5 h / 45 °C
2.2: 1.5 h
3.1: hydrogenchloride / water; ethyl acetate / pH 4
View Scheme
Multi-step reaction with 4 steps
1.1: sodium t-butanolate / 1-methyl-pyrrolidin-2-one; 2-methyltetrahydrofuran; tetrahydrofuran / -60 - 22 °C
2.1: hydrogenchloride / acetonitrile; water / 2.5 h / 45 °C
2.2: 1.5 h / 10 °C
3.1: sodium hydroxide / water / pH 12.3
3.2: 1.25 h / pH 9.7
4.1: hydrogenchloride / water; ethyl acetate / pH 4
View Scheme
pitavastatin-furfuryl amine salt

pitavastatin-furfuryl amine salt

pitavastatin
147526-32-7

pitavastatin

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: sodium hydroxide / water / pH 12.3
1.2: 1.25 h / pH 9.7
2.1: hydrogenchloride / water; ethyl acetate / pH 4
View Scheme
C13H12BrNO

C13H12BrNO

pitavastatin
147526-32-7

pitavastatin

Conditions
ConditionsYield
Multi-step reaction with 7 steps
1.1: Dess-Martin periodane / dichloromethane / 3 h / 0 - 20 °C / Inert atmosphere
2.1: sodium hydride / tetrahydrofuran; mineral oil / 1 h / 0 °C / Inert atmosphere
2.2: 0 - 20 °C / Inert atmosphere
3.1: hydrogenchloride / acetonitrile / 19 h / 0 - 20 °C
4.1: diethyl methoxy borane; sodium tetrahydroborate / methanol; tetrahydrofuran / 1.33 h / -78 °C
4.2: 3 h / 20 °C
5.1: dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH2Cl2; potassium carbonate / dimethyl sulfoxide / 4 h / 70 °C / Inert atmosphere
6.1: dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH2Cl2; tetrakis(triphenylphosphine) palladium(0); sodium carbonate / dimethyl sulfoxide / 9 h / 90 °C / Inert atmosphere
7.1: sodium hydroxide / methanol / 0.5 h / 20 °C
View Scheme
anthranilic acid nitrile
1885-29-6

anthranilic acid nitrile

pitavastatin
147526-32-7

pitavastatin

Conditions
ConditionsYield
Multi-step reaction with 10 steps
1.1: tin(IV) chloride / toluene / 3 h / 15 °C / Inert atmosphere; Reflux
2.1: copper(I) bromide; tert.-butylnitrite / acetonitrile / 2.5 h / 15 - 40 °C / Inert atmosphere
3.1: diisobutylaluminium hydride / toluene; hexane / 1 h / 0 - 20 °C / Inert atmosphere
4.1: Dess-Martin periodane / dichloromethane / 3 h / 0 - 20 °C / Inert atmosphere
5.1: sodium hydride / tetrahydrofuran; mineral oil / 1 h / 0 °C / Inert atmosphere
5.2: 0 - 20 °C / Inert atmosphere
6.1: hydrogenchloride / acetonitrile / 19 h / 0 - 20 °C
7.1: diethyl methoxy borane; sodium tetrahydroborate / methanol; tetrahydrofuran / 1.33 h / -78 °C
7.2: 3 h / 20 °C
8.1: dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH2Cl2; potassium carbonate / dimethyl sulfoxide / 4 h / 70 °C / Inert atmosphere
9.1: dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH2Cl2; tetrakis(triphenylphosphine) palladium(0); sodium carbonate / dimethyl sulfoxide / 9 h / 90 °C / Inert atmosphere
10.1: sodium hydroxide / methanol / 0.5 h / 20 °C
View Scheme
methyl (4-amino-2-cyclopropylquinolin-3-yl)carboxylate

methyl (4-amino-2-cyclopropylquinolin-3-yl)carboxylate

pitavastatin
147526-32-7

pitavastatin

Conditions
ConditionsYield
Multi-step reaction with 9 steps
1.1: copper(I) bromide; tert.-butylnitrite / acetonitrile / 2.5 h / 15 - 40 °C / Inert atmosphere
2.1: diisobutylaluminium hydride / toluene; hexane / 1 h / 0 - 20 °C / Inert atmosphere
3.1: Dess-Martin periodane / dichloromethane / 3 h / 0 - 20 °C / Inert atmosphere
4.1: sodium hydride / tetrahydrofuran; mineral oil / 1 h / 0 °C / Inert atmosphere
4.2: 0 - 20 °C / Inert atmosphere
5.1: hydrogenchloride / acetonitrile / 19 h / 0 - 20 °C
6.1: diethyl methoxy borane; sodium tetrahydroborate / methanol; tetrahydrofuran / 1.33 h / -78 °C
6.2: 3 h / 20 °C
7.1: dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH2Cl2; potassium carbonate / dimethyl sulfoxide / 4 h / 70 °C / Inert atmosphere
8.1: dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH2Cl2; tetrakis(triphenylphosphine) palladium(0); sodium carbonate / dimethyl sulfoxide / 9 h / 90 °C / Inert atmosphere
9.1: sodium hydroxide / methanol / 0.5 h / 20 °C
View Scheme
pitavastatin
147526-32-7

pitavastatin

C25H22FNO3

C25H22FNO3

Conditions
ConditionsYield
With potassium tert-butylate In tetrahydrofuran at 5 - 20℃; Inert atmosphere;82%
pitavastatin
147526-32-7

pitavastatin

(3R,5S,6E)-7-<2-cyclopropyl-4-(4-fluorophenyl)-quinolin-3-yl>-3,5-dihydroxy-6-heptenoic acid 1,5-lactone

(3R,5S,6E)-7-<2-cyclopropyl-4-(4-fluorophenyl)-quinolin-3-yl>-3,5-dihydroxy-6-heptenoic acid 1,5-lactone

Conditions
ConditionsYield
With trifluoroacetic acid In dichloromethane at 0 - 30℃; for 3h;81%
In toluene for 1h; Heating;
berberine chloride
633-65-8

berberine chloride

pitavastatin
147526-32-7

pitavastatin

C25H23FNO4(1-)*C20H18NO4(1+)

C25H23FNO4(1-)*C20H18NO4(1+)

Conditions
ConditionsYield
With sodium hydroxide In ethanol; water at 60 - 70℃; pH=7 - 8;81%
pitavastatin
147526-32-7

pitavastatin

(±)-E-6-[2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-ylvinyl]-4-hydroxy-3,4,5,6-tetrahydrovalerolactone

(±)-E-6-[2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-ylvinyl]-4-hydroxy-3,4,5,6-tetrahydrovalerolactone

Conditions
ConditionsYield
In toluene for 12h; Heating; Yield given;
(R)-1-(1-Naphthyl)ethylamine
3886-70-2

(R)-1-(1-Naphthyl)ethylamine

pitavastatin
147526-32-7

pitavastatin

(3R,5S,E)-7-(2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)-3,5-dihydroxyhept-6-enoic acid (R)-NEA salt
1213706-08-1

(3R,5S,E)-7-(2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)-3,5-dihydroxyhept-6-enoic acid (R)-NEA salt

Conditions
ConditionsYield
In hexane; acetone at 20℃; for 16h;

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