MK-677 Mol Download Chemical properties CAS: 159634-47-6 MF: C27H36N4O5S MW: 528.66 EINECS: 231-830-3 MDL No.: MFCD00867473 Properties Density 1.32 pka 15.73±0.46(Predicted) InChIKey UMUPQWIGCOZEOY-JOCHJYFZSA-N SMILES C(
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inquiryAbout us We are a Professionally Managed Biotech Company exclusively into the manufacturing, Marketing and Exporting of Plant Extracts and Health Care Products.There are 15 experts in our research team. We insist in innovation an
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inquiry1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s
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inquiryIbutamoren Basic information Product Name: Ibutamoren Synonyms: 2-Amino-N-[(1R)-2-[1,2-dihydro-1-(methylsulfonyl)spiro[3H-indole-3,4'-piperidin]-1'-yl]-2-oxo-1-[(phenylmethoxy)methyl]ethyl]-2-methylpropanamide;IbutaMoren (MK-677);2-amin
Our Advantage Rich Experience Our products are sold all over Europe,North&South America, Sino-East, Asia and pacific area as well as Africa,we establish long term. Quality service Company cooperates with research institutes. We strictly con
WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et
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inquiryOur Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We
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inquiryAdvantages: Hubei XinRunde Chemical Co., Ltd is a renowned pharmaceutical manufacturer. We can offer high quality products at competitive price in quick delivery with 100% custom pass guaranteed. Never stop striving to offer our best s
1.In No Less 10 years exporting experience. you can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specializ
MK-677 CAS:159634-47-6 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic intermediates, st
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inquiryHello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai
Product Detail Minimum Order Qty. 10 Gram Supply Ability 500 Kilograms/Month Storage store in cool, dry, ventilated place 20℃ Delivery Time 3 business days after payment Payment Term TT,western union,Paypal,
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inquiryHenan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod
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1,we produce and sell good chemicals around the world. 2,our success rate is about 95%. this means, if customer order is accepted, the probability that the customer will obtain the ordered substances, is 95%. 3,our staff consists of highly qu
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inquiryJ&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia
Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi
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Cas:159634-47-6
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inquiryProduct Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,
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inquiryOur Advantages A. International Top level TechnologyOur company owned biomedicine experts are famous at home and abroad with rich experience in research and development in the field of efficient chiral functional molecules research and development an
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inquiry1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer
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inquiryWe have most reliable quality, competitive prices and full documents for this APIs 1. GMP WORKSHOP 2. DMF Application:pharmaceutical API
GOLDEN PHARMA CO.,LIMITED.is a professional pharmaceutical company,our team have more than 20years expereince in pharmaceutical production and sales. we are a professional technical enterprise specializing in the R & D, production,QA regulation
N-[(R)-[(1,2-Dihydro-1-methanesulfonylspiro[3H-indole-3,4'-piperidin]-1'-yl)carbonyl]-2-(phenylmethyloxy)ethyl]-2-[(1,1-dimethyl-ethoxy)carbonyl]amino-2-methyl-propanamide
Ibutamoren
Conditions | Yield |
---|---|
With methanesulfonic acid In ethanol at 35 - 40℃; Yield given; |
isonipecotic acid
Ibutamoren
Conditions | Yield |
---|---|
Multi-step reaction with 11 steps 1: 97 percent / K2CO3 / H2O / 58 h / 22 °C 2: (COCl)2 / toluene; dimethylformamide / 16 h / 18 °C 3: 94 percent / H2, DIEA, thioanisole / Pd/C / toluene / 22 h / 20 °C / 2068.6 Torr 4: 99 percent / TFA / CH2Cl2 / 17 h / 35 °C 5: NaBH4 / toluene / 0.5 h / -2 °C 6: DIEA / tetrahydrofuran / 2 h / 5 - 8 °C 7: 93 percent / H2 / Pd-C / ethanol / 5 h / 65 °C / 2068.6 Torr 8: DCC, HOBt / H2O; various solvent(s) / 5 h / Ambient temperature 9: MsOH / ethanol / 7.5 h / 35 - 40 °C 10: DCC, HOBt / various solvent(s) / 2 h / Ambient temperature 11: MsOH / ethanol / 35 - 40 °C View Scheme |
N-Boc-D-serine(Bzl)-OH
Ibutamoren
Conditions | Yield |
---|---|
Multi-step reaction with 4 steps 1: DCC, HOBt / H2O; various solvent(s) / 5 h / Ambient temperature 2: MsOH / ethanol / 7.5 h / 35 - 40 °C 3: DCC, HOBt / various solvent(s) / 2 h / Ambient temperature 4: MsOH / ethanol / 35 - 40 °C View Scheme |
Conditions | Yield |
---|---|
Multi-step reaction with 5 steps 1: 74 percent / NaOt-Am / dimethylformamide / 1 h / -10 °C 2: DCC, HOBt / H2O; various solvent(s) / 5 h / Ambient temperature 3: MsOH / ethanol / 7.5 h / 35 - 40 °C 4: DCC, HOBt / various solvent(s) / 2 h / Ambient temperature 5: MsOH / ethanol / 35 - 40 °C View Scheme |
1-benzyloxycarbonylpiperidine-4-carboxylic acid
Ibutamoren
Conditions | Yield |
---|---|
Multi-step reaction with 10 steps 1: (COCl)2 / toluene; dimethylformamide / 16 h / 18 °C 2: 94 percent / H2, DIEA, thioanisole / Pd/C / toluene / 22 h / 20 °C / 2068.6 Torr 3: 99 percent / TFA / CH2Cl2 / 17 h / 35 °C 4: NaBH4 / toluene / 0.5 h / -2 °C 5: DIEA / tetrahydrofuran / 2 h / 5 - 8 °C 6: 93 percent / H2 / Pd-C / ethanol / 5 h / 65 °C / 2068.6 Torr 7: DCC, HOBt / H2O; various solvent(s) / 5 h / Ambient temperature 8: MsOH / ethanol / 7.5 h / 35 - 40 °C 9: DCC, HOBt / various solvent(s) / 2 h / Ambient temperature 10: MsOH / ethanol / 35 - 40 °C View Scheme |
N-(benzyloxycarbonyl)piperidine-4-carboxaldehyde
Ibutamoren
Conditions | Yield |
---|---|
Multi-step reaction with 8 steps 1: 99 percent / TFA / CH2Cl2 / 17 h / 35 °C 2: NaBH4 / toluene / 0.5 h / -2 °C 3: DIEA / tetrahydrofuran / 2 h / 5 - 8 °C 4: 93 percent / H2 / Pd-C / ethanol / 5 h / 65 °C / 2068.6 Torr 5: DCC, HOBt / H2O; various solvent(s) / 5 h / Ambient temperature 6: MsOH / ethanol / 7.5 h / 35 - 40 °C 7: DCC, HOBt / various solvent(s) / 2 h / Ambient temperature 8: MsOH / ethanol / 35 - 40 °C View Scheme |
benzyl 4-(chlorocarbonyl)piperidine-1-carboxylate
Ibutamoren
Conditions | Yield |
---|---|
Multi-step reaction with 9 steps 1: 94 percent / H2, DIEA, thioanisole / Pd/C / toluene / 22 h / 20 °C / 2068.6 Torr 2: 99 percent / TFA / CH2Cl2 / 17 h / 35 °C 3: NaBH4 / toluene / 0.5 h / -2 °C 4: DIEA / tetrahydrofuran / 2 h / 5 - 8 °C 5: 93 percent / H2 / Pd-C / ethanol / 5 h / 65 °C / 2068.6 Torr 6: DCC, HOBt / H2O; various solvent(s) / 5 h / Ambient temperature 7: MsOH / ethanol / 7.5 h / 35 - 40 °C 8: DCC, HOBt / various solvent(s) / 2 h / Ambient temperature 9: MsOH / ethanol / 35 - 40 °C View Scheme |
phenylhydrazine
Ibutamoren
Conditions | Yield |
---|---|
Multi-step reaction with 8 steps 1: 99 percent / TFA / CH2Cl2 / 17 h / 35 °C 2: NaBH4 / toluene / 0.5 h / -2 °C 3: DIEA / tetrahydrofuran / 2 h / 5 - 8 °C 4: 93 percent / H2 / Pd-C / ethanol / 5 h / 65 °C / 2068.6 Torr 5: DCC, HOBt / H2O; various solvent(s) / 5 h / Ambient temperature 6: MsOH / ethanol / 7.5 h / 35 - 40 °C 7: DCC, HOBt / various solvent(s) / 2 h / Ambient temperature 8: MsOH / ethanol / 35 - 40 °C View Scheme |
1-(methylsulfonyl)spiro[indoline-3,4’-piperidine]
Ibutamoren
Conditions | Yield |
---|---|
Multi-step reaction with 4 steps 1: DCC, HOBt / H2O; various solvent(s) / 5 h / Ambient temperature 2: MsOH / ethanol / 7.5 h / 35 - 40 °C 3: DCC, HOBt / various solvent(s) / 2 h / Ambient temperature 4: MsOH / ethanol / 35 - 40 °C View Scheme |
benzyl spiro[indole-3,4'-piperidine]-1'-carboxylate
Ibutamoren
Conditions | Yield |
---|---|
Multi-step reaction with 7 steps 1: NaBH4 / toluene / 0.5 h / -2 °C 2: DIEA / tetrahydrofuran / 2 h / 5 - 8 °C 3: 93 percent / H2 / Pd-C / ethanol / 5 h / 65 °C / 2068.6 Torr 4: DCC, HOBt / H2O; various solvent(s) / 5 h / Ambient temperature 5: MsOH / ethanol / 7.5 h / 35 - 40 °C 6: DCC, HOBt / various solvent(s) / 2 h / Ambient temperature 7: MsOH / ethanol / 35 - 40 °C View Scheme |
benzyl spiro[indoline-3,4’-piperidine]-1‘-carboxylate
Ibutamoren
Conditions | Yield |
---|---|
Multi-step reaction with 6 steps 1: DIEA / tetrahydrofuran / 2 h / 5 - 8 °C 2: 93 percent / H2 / Pd-C / ethanol / 5 h / 65 °C / 2068.6 Torr 3: DCC, HOBt / H2O; various solvent(s) / 5 h / Ambient temperature 4: MsOH / ethanol / 7.5 h / 35 - 40 °C 5: DCC, HOBt / various solvent(s) / 2 h / Ambient temperature 6: MsOH / ethanol / 35 - 40 °C View Scheme |
benzyl 1-(methylsulfonyl)spiro[indoline-3,4’-piperidine]-1‘-carboxylate
Ibutamoren
Conditions | Yield |
---|---|
Multi-step reaction with 5 steps 1: 93 percent / H2 / Pd-C / ethanol / 5 h / 65 °C / 2068.6 Torr 2: DCC, HOBt / H2O; various solvent(s) / 5 h / Ambient temperature 3: MsOH / ethanol / 7.5 h / 35 - 40 °C 4: DCC, HOBt / various solvent(s) / 2 h / Ambient temperature 5: MsOH / ethanol / 35 - 40 °C View Scheme |
C23H29N3O4S
Ibutamoren
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: DCC, HOBt / various solvent(s) / 2 h / Ambient temperature 2: MsOH / ethanol / 35 - 40 °C View Scheme |
C28H37N3O6S
Ibutamoren
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: MsOH / ethanol / 7.5 h / 35 - 40 °C 2: DCC, HOBt / various solvent(s) / 2 h / Ambient temperature 3: MsOH / ethanol / 35 - 40 °C View Scheme |
Conditions | Yield |
---|---|
In ethanol; ethyl acetate at 55℃; Yield given; |
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