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Dayang Chem (Hangzhou) Co.,Ltd.

DayangChem exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, DayangChem is your best choice. Pls contact with us freely for getting detailed product s

5-Bromo-7-azaindole

Cas:183208-35-7

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality 5-Bromo-7-Azaindole supplier in China

Cas:183208-35-7

Min.Order:1 Metric Ton

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Hangzhou Dingyan Chem Co., Ltd

Analysis tests Standard Results Appearance Yellowish Crystallization Hangzhou Dingyan Chem is a leading manufacturer and supplie

High quality 5-Bromo-7-azaindole with best price cas:183208-35-7

Cas:183208-35-7

Min.Order:1 Kilogram

FOB Price: $250.0 / 350.0

Type:Manufacturers

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Jinan Finer Chemical Co., Ltd

Product Description Product website: http://www.finerchem.com/pro01en/id/2049.html Product Name 5-Bromo-7-azaindole CAS No. 183208-35-7

5-Bromo-7-azaindole

Cas:183208-35-7

Min.Order:1 Gram

FOB Price: $22.0

Type:Lab/Research institutions

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Hangzhou Think Chemical Co. Ltd

5-Bromo-7-azaindole CAS No.:183208-35-7 Name: 5-Bromo-7-azaindole Synonyms: 5-Bromo-1H-pyrrolo[2,3-b]pyridine Molecular Structure Molecular Formula: C7H5BrN2 Molecular Weight: 197.03 CAS Re

High purity 5-Bromo-7-azaindole CAS No.:183208-35-7

Cas:183208-35-7

Min.Order:1 Kilogram

FOB Price: $2.0

Type:Other

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Henan Allgreen Chemical Co.,Ltd

Good quality Good price Promptly delivery Appearance:White or off-white Solid Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:intermediate Transportation:Ac

183208-35-75-Bromo-7-azaindole

Cas:183208-35-7

Min.Order:1 Kilogram

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Type:Manufacturers

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply 5-bromo-1H-pyrrolo[2,3-b]pyridine

Cas:183208-35-7

Min.Order:1

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Type:Other

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Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

High Quality 99% 183208-35-7 5-BROMO-1H-PYRROLO[2,3-B]PYRIDINE Manufacturer

Cas:183208-35-7

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

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COLORCOM LTD.

Colorcom is a global leader in industrial chemical manufacturing and is continuously innovating and transforming to exceed client expectations and industry standards. Colorcom prides itself on superior customer and technical focus, while focusing on

5-Bromo-7-azaindole

Cas:183208-35-7

Min.Order:1 Metric Ton

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Type:Manufacturers

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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

5-Bromo-1H-pyrrolo[2,3-b]pyridine

Cas:183208-35-7

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

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Leader Biochemical Group

About Product Details

China Biggest factory Supply High Quality 5-Bromo-7-azaindole CAS 183208-35-7

Cas:183208-35-7

Min.Order:1 Kilogram

FOB Price: $1.0 / 5.0

Type:Lab/Research institutions

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Hebei Nengqian Chemical Import and Export Co., LTD

Density: 1.79 ± 0.1 g/cm3 (Predicted) Melting point: 176-180 ° C Boiling point: 357.4 ± 42.0 ° C (Predicted) Refractive index: 1.728 Acidity coefficient: 6.25 ± 0.20 (Predicted) Storage conditions: Sealed in dry, Room Tem

5-Bromo-7-azaindole 183208-35-7

Cas:183208-35-7

Min.Order:5 Kilogram

FOB Price: $20.0 / 80.0

Type:Trading Company

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Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.

183208-35-7 5-Bromo-7-azaindole

Cas:183208-35-7

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Factory direct supply CAS 183208-35-7 with best quality

Cas:183208-35-7

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Henan Sinotech Import&Export Corporation

Products: 5-bromo-1H-pyrrolo[2,3-b]pyridine Cas No.: 183208-35-7 Molecular Formula: C7H5BrN2 Molecular Weight: 197.03 Assay: 98% HPLC Molecular Structure: Appearance

5-Bromo-7-azaindole CAS:183208-35-7

Cas:183208-35-7

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Other

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Henan Wentao Chemical Product Co., Ltd.

We are leading fine chemicals supplier in China with ISO certificate, Our main business covers the fields below: 1.Noble Metal Catalysts (Pt.Pd...) 2.Organic Phosphine Ligands (Tert-butyl-phosphine.Cyclohexyl-phosphine...) 3.OLED

5-Bromo-1H-pyrrolo[2,3-b]pyridineCAS NO.: 183208-35-7

Cas:183208-35-7

Min.Order:1 Gram

FOB Price: $2.0

Type:Lab/Research institutions

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Hubei Langyou International Trading Co., Ltd

1. Guaranteed purity; 2. Large quantity in stock; 3. Largest manufacturer; 4. Best service after shipment with email; 5. High quality & competitive price; Appearance:Powder Storage:Store in sealed containers at cool & dry pla

5-Bromo-7-azaindole CAS No.183208-35-7

Cas:183208-35-7

Min.Order:100 Gram

Negotiable

Type:Other

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Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

5-Bromo-1H-pyrrolo[2,3-b]pyridine 183208-35-7

Cas:183208-35-7

Min.Order:1 Kilogram

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Type:Lab/Research institutions

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Shanghai Minstar Chemical Co., Ltd

Product Name: 5-Bromo-7-azaindole CAS: 183208-35-7 MF: C7H5BrN2 MW: 197.03 EINECS: 629-247-8 Mol File: 183208-35-7.mol 5-Bromo-7-azaindole Structure 5-Bromo-7-azaindole Chemical Properties Melting point 176-180 °C Boiling

5-Bromo-1H-pyrrolo[2,3b]pyridine

Cas:183208-35-7

Min.Order:1 Gram

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Type:Lab/Research institutions

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Baoji Guokang Healthchem co.,ltd

Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At prese

5-Bromo-7-azaindole, 99%

Cas:183208-35-7

Min.Order:1 Kilogram

FOB Price: $85.0 / 100.0

Type:Trading Company

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Qingdao Beluga Import and Export Co., LTD

5-Bromo-7-azaindole CAS:183208-35-7 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic int

5-Bromo-7-azaindole CAS:183208-35-7

Cas:183208-35-7

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

5-Bromo-1H-pyrrolo[2,3-b]pyridine

Cas:183208-35-7

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Xiamen Hisunny Chemical Co.,Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia

5-Bromo-7-Azaindole

Cas:183208-35-7

Min.Order:0

Negotiable

Type:Manufacturers

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Triumph International Development Limilted

Triumph has the complete production of G- KG - MT service chain,we can make the new technology into productivity quickly in the research and development of new products. Main Service 1.Own made fine chemical products 2.Out sourcing and qua

5-BroMo-7-azaindole

Cas:183208-35-7

Min.Order:100 Gram

Negotiable

Type:Lab/Research institutions

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Taizhou Crene Biotechnology co.ltd

Our company provides one-stop services of research - development - production for a variety of special prouducts. Not only do we make effective use of our strong technological strength, but also establish of cooperative relations with several well-

5-Bromo-7-azaindole 183208-35-7

Cas:183208-35-7

Min.Order:100 Gram

Negotiable

Type:Lab/Research institutions

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Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

5-Bromo-7-azaindole

Cas:183208-35-7

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

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Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

5-Bromo-7-azaindole

Cas:183208-35-7

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

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Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

5-bromo-1H-pyrrolo[2 , 3-b]pyridine

Cas:183208-35-7

Min.Order:0

Negotiable

Type:Lab/Research institutions

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SHANGHAI T&W PHARMACEUTICAL CO., LTD.

A substitute for perfluorooctanoic acid, mainly used as a surfactant, dispersant, additive, etc Appearance:White solid or Colorless liquid Purity:99.3 % We will ship the goods in a timely manner as required We can provide relevant documents acc

5-Bromo-1H-pyrrolo[2,3-b]pyridine

Cas:183208-35-7

Min.Order:4 Kilogram

Negotiable

Type:Lab/Research institutions

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Hangzhou Lingrui Chemical Co.,Ltd.

our strengths: 1: Fast and guaranteed shipment (TNT;EMS;FEDEX;DHL;UPS;EUB, special line) 2: Various payment items accepted (Btc; MoneyGram; WU) 3: Valued package (Paraffin coating; Double aluminum foil bag; Vacuum packaging) 4: Efficient delivery

5-Bromo-7-azaindole in stock

Cas:183208-35-7

Min.Order:1 Gram

Negotiable

Type:Other

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Synthetic route

7-aza-5-bromoindoline
115170-40-6

7-aza-5-bromoindoline

5-bromo-1H-pyrrolo[2,3-b]pyridine
183208-35-7

5-bromo-1H-pyrrolo[2,3-b]pyridine

Conditions
ConditionsYield
With manganese(IV) oxide In dichloromethane for 72h;100%
With manganese(IV) oxide In toluene for 4h; Reflux;90%
With activated carbon fiber catalyst In 5,5-dimethyl-1,3-cyclohexadiene at 100℃; for 8h; Solvent;85.43%
5-bromo-1-(tert-butyl-dimethyl-silanyl)-1H-pyrrolo[2,3-b]pyridine
754214-54-5

5-bromo-1-(tert-butyl-dimethyl-silanyl)-1H-pyrrolo[2,3-b]pyridine

5-bromo-1H-pyrrolo[2,3-b]pyridine
183208-35-7

5-bromo-1H-pyrrolo[2,3-b]pyridine

Conditions
ConditionsYield
With hydrogenchloride In methanol for 0.133333h;94%
With tetrabutyl ammonium fluoride In tetrahydrofuran at 25℃; for 0.5h;
2-nitro-3-dimethylaminovinyl-5-bromopyridine

2-nitro-3-dimethylaminovinyl-5-bromopyridine

5-bromo-1H-pyrrolo[2,3-b]pyridine
183208-35-7

5-bromo-1H-pyrrolo[2,3-b]pyridine

Conditions
ConditionsYield
With sodium at 20 - 60℃; for 1.5h; Temperature; Inert atmosphere;92.9%

Conditions
ConditionsYield
With potassium hydroxide In 1,2-dimethoxyethane at 140℃; for 16h; Industrial scale;91.5%
5-bromo-3-ethynyl-pyridin-2-ylamine

5-bromo-3-ethynyl-pyridin-2-ylamine

5-bromo-1H-pyrrolo[2,3-b]pyridine
183208-35-7

5-bromo-1H-pyrrolo[2,3-b]pyridine

Conditions
ConditionsYield
With potassium tert-butylate In N,N-dimethyl-formamide at 60 - 85℃; Large scale;90%
Stage #1: 5-bromo-3-ethynyl-pyridin-2-ylamine With potassium tert-butylate In 1-methyl-pyrrolidin-2-one at 60℃; for 3h;
Stage #2: With water In 1-methyl-pyrrolidin-2-one; toluene
(E)-N'-(5-bromo-3-methylpyridin-2-yl)-N-methyl-N-phenylmethanimidamide

(E)-N'-(5-bromo-3-methylpyridin-2-yl)-N-methyl-N-phenylmethanimidamide

5-bromo-1H-pyrrolo[2,3-b]pyridine
183208-35-7

5-bromo-1H-pyrrolo[2,3-b]pyridine

Conditions
ConditionsYield
With sodium amide In diethylene glycol dimethyl ether at 10 - 15℃; for 16h; Industrial scale;87.6%
C9H13Br2NO3

C9H13Br2NO3

5-bromo-1H-pyrrolo[2,3-b]pyridine
183208-35-7

5-bromo-1H-pyrrolo[2,3-b]pyridine

Conditions
ConditionsYield
With ammonium hydroxide; potassium carbonate; ammonium chloride In tetrahydrofuran at 25 - 60℃; for 4h;86.8%
4-(2-amino-5-bromopyridin-3-yl)-2-methylbut-3-yn-2-ol
1262985-25-0

4-(2-amino-5-bromopyridin-3-yl)-2-methylbut-3-yn-2-ol

5-bromo-1H-pyrrolo[2,3-b]pyridine
183208-35-7

5-bromo-1H-pyrrolo[2,3-b]pyridine

Conditions
ConditionsYield
With sodium hydroxide In water; glycerol at 80℃; for 15h; Solvent;86.6%
With sodium hydroxide In 1-methyl-pyrrolidin-2-one; water at 75 - 81℃; under 262.526 Torr; Inert atmosphere;75%
2-aminopyrrole
4458-15-5

2-aminopyrrole

bromomalonaldehyde; sodium enolate

bromomalonaldehyde; sodium enolate

5-bromo-1H-pyrrolo[2,3-b]pyridine
183208-35-7

5-bromo-1H-pyrrolo[2,3-b]pyridine

Conditions
ConditionsYield
With hydrogen bromide In ethanol Reflux;85.5%
5-bromo-3-(2-(trimethylsilyl)ethynyl)pyridine-2-amine
905966-34-9

5-bromo-3-(2-(trimethylsilyl)ethynyl)pyridine-2-amine

5-bromo-1H-pyrrolo[2,3-b]pyridine
183208-35-7

5-bromo-1H-pyrrolo[2,3-b]pyridine

Conditions
ConditionsYield
With sodium hydride In 1-methyl-pyrrolidin-2-one at 80℃; for 1h; Inert atmosphere;80%
With potassium tert-butylate In 1-methyl-pyrrolidin-2-one at 80℃; for 1h;70%
Stage #1: 5-bromo-3-(2-(trimethylsilyl)ethynyl)pyridine-2-amine With potassium tert-butylate In tert-butyl alcohol for 12h; Heating / reflux;
Stage #2: With hydrogenchloride In water; tert-butyl alcohol at 20℃; for 12h; Heating / reflux;
Stage #3: With sodium hydroxide In water; tert-butyl alcohol
60%
Stage #1: 5-bromo-3-(2-(trimethylsilyl)ethynyl)pyridine-2-amine With potassium tert-butylate In tert-butyl alcohol
Stage #2: With hydrogenchloride In water; tert-butyl alcohol
56%
With potassium tert-butylate In 1-methyl-pyrrolidin-2-one at 20 - 80℃; for 1h; Product distribution / selectivity;53%
5-bromo-1,3-dihydro-2H-pyrrolo[2,3-b]pyridin-2-one
183208-34-6

5-bromo-1,3-dihydro-2H-pyrrolo[2,3-b]pyridin-2-one

5-bromo-1H-pyrrolo[2,3-b]pyridine
183208-35-7

5-bromo-1H-pyrrolo[2,3-b]pyridine

Conditions
ConditionsYield
Stage #1: 5-bromo-1,3-dihydro-2H-pyrrolo[2,3-b]pyridin-2-one With hydrogenchloride; tin In ethanol; water at 40℃; for 2h;
Stage #2: With copper(ll) bromide In chloroform at 60℃; for 2h; Solvent; Temperature; Reagent/catalyst;
77.6%
Stage #1: 5-bromo-1,3-dihydro-2H-pyrrolo[2,3-b]pyridin-2-one With borane-THF In tetrahydrofuran at 0 - 20℃; for 0.583333h;
Stage #2: With manganese triacetate In acetic acid at 75℃; for 0.75h;
50%
Stage #1: 5-bromo-1,3-dihydro-2H-pyrrolo[2,3-b]pyridin-2-one With borane-THF In tetrahydrofuran at 20℃; for 0.833333h;
Stage #2: With manganese triacetate; acetic acid at 75℃; for 0.833333h; Further stages.;
50%
Stage #1: 5-bromo-1,3-dihydro-2H-pyrrolo[2,3-b]pyridin-2-one With borane-THF In tetrahydrofuran at 0 - 20℃;
Stage #2: With manganese(III) triacetate dihydrate; acetic acid In tetrahydrofuran at 75℃;
50%
With hydrogenchloride; borane-THF; manganese triacetate 1.) THF, 0 deg C, 35 min, RT, 2.) H2O, reflux, 3.) acetic acid, 45 min, 75 deg C; Yield given; Multistep reaction;
1-phenylbut-3-yn-1-ol
1743-36-8

1-phenylbut-3-yn-1-ol

5-bromo-1H-pyrrolo[2,3-b]pyridine
183208-35-7

5-bromo-1H-pyrrolo[2,3-b]pyridine

Conditions
ConditionsYield
With di-isopropyl azodicarboxylate; diphenyl phosphoryl azide; triphenylphosphine In tetrahydrofuran at 20℃; for 24h;75%
N-(5-bromo-3-trimethylsilanylethynyl-pyridin-2-yl)-acetamide
875639-46-6

N-(5-bromo-3-trimethylsilanylethynyl-pyridin-2-yl)-acetamide

5-bromo-1H-pyrrolo[2,3-b]pyridine
183208-35-7

5-bromo-1H-pyrrolo[2,3-b]pyridine

Conditions
ConditionsYield
With tetrabutyl ammonium fluoride In tetrahydrofuran for 15h; Heating / reflux;67%
With tetrabutyl ammonium fluoride In tetrahydrofuran for 15h; Heating / reflux;67%
N'-(5-bromo-3-methylpyridin-2-yl)-N-methyl-N-phenylmethanimidamide

N'-(5-bromo-3-methylpyridin-2-yl)-N-methyl-N-phenylmethanimidamide

5-bromo-1H-pyrrolo[2,3-b]pyridine
183208-35-7

5-bromo-1H-pyrrolo[2,3-b]pyridine

Conditions
ConditionsYield
With sodium amide; N-methylaniline for 2h; Reagent/catalyst; Temperature; Inert atmosphere; Reflux;60%
N'-(5-bromo-3-methyl-pyridin-2-yl)-N,N-dimethyl-formamidine
883052-76-4

N'-(5-bromo-3-methyl-pyridin-2-yl)-N,N-dimethyl-formamidine

5-bromo-1H-pyrrolo[2,3-b]pyridine
183208-35-7

5-bromo-1H-pyrrolo[2,3-b]pyridine

Conditions
ConditionsYield
Stage #1: N'-(5-bromo-3-methyl-pyridin-2-yl)-N,N-dimethyl-formamidine With lithium diisopropyl amide In tetrahydrofuran at -30℃;
Stage #2: With acetic acid In tetrahydrofuran Product distribution / selectivity;
26%
Stage #1: N'-(5-bromo-3-methyl-pyridin-2-yl)-N,N-dimethyl-formamidine With lithium diisopropyl amide In tetrahydrofuran at -30℃;
Stage #2: With acetic acid In tetrahydrofuran Product distribution / selectivity;
26%
(E)-N’-(5-bromo-3-methylpyridin-2-yl)-N,N-dimethylformimidamide

(E)-N’-(5-bromo-3-methylpyridin-2-yl)-N,N-dimethylformimidamide

5-bromo-1H-pyrrolo[2,3-b]pyridine
183208-35-7

5-bromo-1H-pyrrolo[2,3-b]pyridine

Conditions
ConditionsYield
Stage #1: (E)-N’-(5-bromo-3-methylpyridin-2-yl)-N,N-dimethylformimidamide With lithium diisopropyl amide In tetrahydrofuran at -30℃; for 5 - 6h;
Stage #2: With acetic acid In tetrahydrofuran for 0.166667h; Product distribution / selectivity;
26%
5-bromo-1H-pyrrolo[2,3-b]pyridin-2(3H)-one

5-bromo-1H-pyrrolo[2,3-b]pyridin-2(3H)-one

5-bromo-1H-pyrrolo[2,3-b]pyridine
183208-35-7

5-bromo-1H-pyrrolo[2,3-b]pyridine

Conditions
ConditionsYield
Stage #1: 5-bromo-1H-pyrrolo[2,3-b]pyridin-2(3H)-one With diborane In tetrahydrofuran at 20℃; for 0.833333h; Inert atmosphere;
Stage #2: With manganese triacetate In acetic acid at 75℃; for 0.833333h;
6%
7-Azaindole
271-63-6

7-Azaindole

n-pentyl halide

n-pentyl halide

5-bromo-1H-pyrrolo[2,3-b]pyridine
183208-35-7

5-bromo-1H-pyrrolo[2,3-b]pyridine

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: 85 percent / bromine / 2-methyl-propan-2-ol; H2O / 24 h / 24.84 °C
2.1: 95 percent / zinc; acetic acid / 5 h / 20 °C
3.1: BH3*THF / tetrahydrofuran / 0.83 h / 20 °C
3.2: 50 percent / Mn(OAc)3*2H2O; acetic acid / 0.83 h / 75 °C
View Scheme
3,3,5-Tribromo-1,3-dihydro-2H-pyrrolo[2,3-b]pyridin-2-one
183208-32-4

3,3,5-Tribromo-1,3-dihydro-2H-pyrrolo[2,3-b]pyridin-2-one

5-bromo-1H-pyrrolo[2,3-b]pyridine
183208-35-7

5-bromo-1H-pyrrolo[2,3-b]pyridine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: 95 percent / zinc; acetic acid / 5 h / 20 °C
2.1: BH3*THF / tetrahydrofuran / 0.83 h / 20 °C
2.2: 50 percent / Mn(OAc)3*2H2O; acetic acid / 0.83 h / 75 °C
View Scheme
Multi-step reaction with 2 steps
1.1: 94 percent / zinc; acetic acid / 20 °C
2.1: borane*tetrahydrofurane / tetrahydrofuran / 0.58 h / 0 - 20 °C
2.2: 50 percent / manganese triacetate / acetic acid / 0.75 h / 75 °C
View Scheme
Multi-step reaction with 2 steps
1: 94 percent / zinc, acetic acid / 3 h / Ambient temperature
2: 1.) borane-THF complex, 2.) 6N HCl, 3.) manganese(III) acetate / 1.) THF, 0 deg C, 35 min, RT, 2.) H2O, reflux, 3.) acetic acid, 45 min, 75 deg C
View Scheme
Multi-step reaction with 2 steps
1.1: zinc; acetic acid / 20 °C
2.1: borane-THF / tetrahydrofuran / 0 - 20 °C
2.2: 75 °C
View Scheme
7-Azaindole
271-63-6

7-Azaindole

5-bromo-1H-pyrrolo[2,3-b]pyridine
183208-35-7

5-bromo-1H-pyrrolo[2,3-b]pyridine

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: 85 percent / bromine / 2-methyl-propan-2-ol; H2O / 20 °C
2.1: 94 percent / zinc; acetic acid / 20 °C
3.1: borane*tetrahydrofurane / tetrahydrofuran / 0.58 h / 0 - 20 °C
3.2: 50 percent / manganese triacetate / acetic acid / 0.75 h / 75 °C
View Scheme
Multi-step reaction with 3 steps
1: 85 percent / bromine / 2-methyl-propan-2-ol; H2O / 19 h / Ambient temperature
2: 94 percent / zinc, acetic acid / 3 h / Ambient temperature
3: 1.) borane-THF complex, 2.) 6N HCl, 3.) manganese(III) acetate / 1.) THF, 0 deg C, 35 min, RT, 2.) H2O, reflux, 3.) acetic acid, 45 min, 75 deg C
View Scheme
C11H15BrN2O
1111638-00-6

C11H15BrN2O

5-bromo-1H-pyrrolo[2,3-b]pyridine
183208-35-7

5-bromo-1H-pyrrolo[2,3-b]pyridine

Conditions
ConditionsYield
Stage #1: C11H15BrN2O With hydrogenchloride In water for 8h; Heating / reflux;
Stage #2: With sodium hydroxide; water
1-(tert-butyl-dimethyl-silanyl)-2,3-dihydro-1H-pyrrolo[2,3-b]pyridine

1-(tert-butyl-dimethyl-silanyl)-2,3-dihydro-1H-pyrrolo[2,3-b]pyridine

5-bromo-1H-pyrrolo[2,3-b]pyridine
183208-35-7

5-bromo-1H-pyrrolo[2,3-b]pyridine

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: bromine; pyridine / dichloromethane / 2 h / 0 °C
2: 2,3-dicyano-5,6-dichloro-p-benzoquinone / dichloromethane / 1 h
3: tetrabutyl ammonium fluoride / tetrahydrofuran / 0.5 h / 25 °C
View Scheme
5-bromo-1-(tert-butyl-dimethyl-silanyl)-2,3-dihydro-1H-pyrrolo[2,3-b]pyridine

5-bromo-1-(tert-butyl-dimethyl-silanyl)-2,3-dihydro-1H-pyrrolo[2,3-b]pyridine

5-bromo-1H-pyrrolo[2,3-b]pyridine
183208-35-7

5-bromo-1H-pyrrolo[2,3-b]pyridine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 2,3-dicyano-5,6-dichloro-p-benzoquinone / dichloromethane / 1 h
2: tetrabutyl ammonium fluoride / tetrahydrofuran / 0.5 h / 25 °C
View Scheme
7-azaindoline
10592-27-5

7-azaindoline

5-bromo-1H-pyrrolo[2,3-b]pyridine
183208-35-7

5-bromo-1H-pyrrolo[2,3-b]pyridine

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 0.5 h / 0 °C
1.2: 3 h / 0 °C
2.1: bromine; pyridine / dichloromethane / 2 h / 0 °C
3.1: 2,3-dicyano-5,6-dichloro-p-benzoquinone / dichloromethane / 1 h
4.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 0.5 h / 25 °C
View Scheme
Multi-step reaction with 2 steps
1: 1,3-dibromo-5,5-dimethylimidazolidine-2,4-dione; toluene-4-sulfonic acid / dichloromethane / 1 h / 20 °C
2: manganese(IV) oxide / toluene / 1 h / 90 °C
View Scheme
2-amino-3-iodo-5-bromopyridine
381233-96-1

2-amino-3-iodo-5-bromopyridine

5-bromo-1H-pyrrolo[2,3-b]pyridine
183208-35-7

5-bromo-1H-pyrrolo[2,3-b]pyridine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: lithium hydroxide / dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH2Cl2 / N,N-dimethyl-formamide / 18 h / 70 °C
2: hydrogenchloride / water / 1 h / 50 °C
View Scheme
Multi-step reaction with 2 steps
1: copper(l) iodide; bis-triphenylphosphine-palladium(II) chloride; triethylamine / 1 h / 20 °C / Inert atmosphere
2: sodium hydride / 1-methyl-pyrrolidin-2-one / 1 h / 80 °C / Inert atmosphere
View Scheme
Multi-step reaction with 2 steps
1: triethylamine; copper(l) iodide; bis-triphenylphosphine-palladium(II) chloride / tetrahydrofuran / 3 h / 20 °C / Inert atmosphere
2: potassium tert-butylate / 1-methyl-pyrrolidin-2-one / 1 h / 80 °C
View Scheme
5-bromo-2-pyridylamine
1072-97-5

5-bromo-2-pyridylamine

5-bromo-1H-pyrrolo[2,3-b]pyridine
183208-35-7

5-bromo-1H-pyrrolo[2,3-b]pyridine

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: trifluoroacetic acid; sodium periodate; iodine / acetonitrile / 80 °C
2: lithium hydroxide / dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH2Cl2 / N,N-dimethyl-formamide / 18 h / 70 °C
3: hydrogenchloride / water / 1 h / 50 °C
View Scheme
Multi-step reaction with 3 steps
1: trifluoroacetic acid; sodium periodate; iodine / acetonitrile / 80 °C
2: N,N,N',N'-tetramethylguanidine; copper(l) iodide / bis-triphenylphosphine-palladium(II) chloride / toluene / 1 h / 80 °C / Inert atmosphere
3: potassium tert-butylate / 1-methyl-pyrrolidin-2-one / 1 h / 20 - 80 °C
View Scheme
Multi-step reaction with 3 steps
1.1: trifluoroacetic acid; N-iodo-succinimide / N,N-dimethyl-formamide / 3 h / 20 - 50 °C
1.2: pH 7
2.1: lithium hydroxide / dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH2Cl2 / 18 h / 70 °C
3.1: hydrogenchloride / water / 1 h / 50 °C
View Scheme
Multi-step reaction with 3 steps
1: periodic acid; iodine / acetonitrile / Inert atmosphere
2: copper(l) iodide; bis-triphenylphosphine-palladium(II) chloride; triethylamine / 1 h / 20 °C / Inert atmosphere
3: sodium hydride / 1-methyl-pyrrolidin-2-one / 1 h / 80 °C / Inert atmosphere
View Scheme
Multi-step reaction with 3 steps
1: acetic acid; sodium periodate; iodine / 2 h / 80 °C
2: dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH2Cl2; copper(l) iodide; triethylamine / dichloromethane / 30 h / Inert atmosphere; Reflux
3: sodium hydroxide / water; glycerol / 15 h / 80 °C
View Scheme
C9H11BrN2O
1356397-50-6

C9H11BrN2O

5-bromo-1H-pyrrolo[2,3-b]pyridine
183208-35-7

5-bromo-1H-pyrrolo[2,3-b]pyridine

Conditions
ConditionsYield
With hydrogenchloride In water at 50℃; for 1h; Product distribution / selectivity;
With hydrogenchloride In water at 50℃; for 1h;
5-bromo-3-methyl-pyridin-2-ylamine
3430-21-5

5-bromo-3-methyl-pyridin-2-ylamine

5-bromo-1H-pyrrolo[2,3-b]pyridine
183208-35-7

5-bromo-1H-pyrrolo[2,3-b]pyridine

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: toluene-4-sulfonic acid / 1 h / 85 °C
2: 2 h / 110 °C
3: N-methylaniline; sodium amide / 2 h / Inert atmosphere; Reflux
View Scheme
Multi-step reaction with 3 steps
1: toluene-4-sulfonic acid / dichloromethane / 16 h / Reflux; Industrial scale
2: toluene / 16 h / 60 °C / Industrial scale
3: sodium amide / diethylene glycol dimethyl ether / 16 h / 10 - 15 °C / Industrial scale
View Scheme
2-amino-3,5-dibromopyridine
35486-42-1

2-amino-3,5-dibromopyridine

5-bromo-1H-pyrrolo[2,3-b]pyridine
183208-35-7

5-bromo-1H-pyrrolo[2,3-b]pyridine

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: toluene-4-sulfonic acid / 5 h / 95 °C / Industrial scale
2.1: sodium hydride / 1,4-dioxane / 2 h / Industrial scale
2.2: 14 h / 80 °C / Industrial scale
3.1: potassium hydroxide / 1,2-dimethoxyethane / 16 h / 140 °C / Industrial scale
View Scheme
5-bromo-1H-pyrrolo[2,3-b]pyridine
183208-35-7

5-bromo-1H-pyrrolo[2,3-b]pyridine

methyl iodide
74-88-4

methyl iodide

5-bromo-1-methyl-1H-pyrrolo[2,3-b]pyridine
183208-22-2

5-bromo-1-methyl-1H-pyrrolo[2,3-b]pyridine

Conditions
ConditionsYield
Stage #1: 5-bromo-1H-pyrrolo[2,3-b]pyridine With sodium hydride In N,N-dimethyl-formamide at 0 - 20℃;
Stage #2: methyl iodide In N,N-dimethyl-formamide at 20℃;
100%
Stage #1: 5-bromo-1H-pyrrolo[2,3-b]pyridine With sodium hydride In N,N-dimethyl-formamide at 0℃; for 0.5h; Inert atmosphere;
Stage #2: methyl iodide In N,N-dimethyl-formamide at 25℃; for 3h; Inert atmosphere;
99%
Stage #1: 5-bromo-1H-pyrrolo[2,3-b]pyridine With sodium hydride In N,N-dimethyl acetamide; mineral oil at 20℃; for 0.5h;
Stage #2: methyl iodide In N,N-dimethyl acetamide; mineral oil for 4h;
97%
5-bromo-1H-pyrrolo[2,3-b]pyridine
183208-35-7

5-bromo-1H-pyrrolo[2,3-b]pyridine

3-iodo-5-bromo-1H-pyrrolo[2,3-b]-pyridine
757978-18-0

3-iodo-5-bromo-1H-pyrrolo[2,3-b]-pyridine

Conditions
ConditionsYield
With N-iodo-succinimide In acetone at 20℃; for 0.333333h;100%
Stage #1: 5-bromo-1H-pyrrolo[2,3-b]pyridine With potassium hydroxide In dichloromethane at 20℃; for 0.5h;
Stage #2: With N-iodo-succinimide In dichloromethane for 15h;
100%
With N-iodo-succinimide In acetone at 20℃; for 0.333333h;100%
Trichloroacetyl chloride
76-02-8

Trichloroacetyl chloride

5-bromo-1H-pyrrolo[2,3-b]pyridine
183208-35-7

5-bromo-1H-pyrrolo[2,3-b]pyridine

1-(5-bromo-1H-pyrrolo[2,3-b]pyridin-3-yl)-2,2,2-trichloroethanone

1-(5-bromo-1H-pyrrolo[2,3-b]pyridin-3-yl)-2,2,2-trichloroethanone

Conditions
ConditionsYield
Stage #1: 5-bromo-1H-pyrrolo[2,3-b]pyridine With aluminum (III) chloride In dichloromethane at 20℃; for 0.166667h;
Stage #2: trifluoroacetyl chloride In dichloromethane at 20℃;
100%
Stage #1: 5-bromo-1H-pyrrolo[2,3-b]pyridine With aluminum (III) chloride In dichloromethane at 0℃; for 3h;
Stage #2: trifluoroacetyl chloride In dichloromethane at 25℃; for 16h;
72%
With aluminum (III) chloride In dichloromethane at 20℃;
Stage #1: 5-bromo-1H-pyrrolo[2,3-b]pyridine With aluminum (III) chloride at 20℃; for 0.166667h; Inert atmosphere;
Stage #2: trifluoroacetyl chloride for 14h;
16.36 g
Stage #1: 5-bromo-1H-pyrrolo[2,3-b]pyridine With aluminum (III) chloride In dichloromethane at 0℃; for 3h;
Stage #2: trifluoroacetyl chloride In dichloromethane at 25℃; for 16h;
(2-trimethylethylsilylethoxy)methyl chloride
76513-69-4

(2-trimethylethylsilylethoxy)methyl chloride

5-bromo-1H-pyrrolo[2,3-b]pyridine
183208-35-7

5-bromo-1H-pyrrolo[2,3-b]pyridine

5-bromo-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-pyrrolo[2,3-b]pyridine

5-bromo-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-pyrrolo[2,3-b]pyridine

Conditions
ConditionsYield
Stage #1: 5-bromo-1H-pyrrolo[2,3-b]pyridine With sodium hydride In N,N-dimethyl-formamide; paraffin oil at 0 - 20℃; for 0.5h; Inert atmosphere;
Stage #2: (2-trimethylethylsilylethoxy)methyl chloride In N,N-dimethyl-formamide; paraffin oil at 0 - 20℃;
100%
Stage #1: 5-bromo-1H-pyrrolo[2,3-b]pyridine With sodium hydride In N,N-dimethyl-formamide at -40℃; for 1h;
Stage #2: (2-trimethylethylsilylethoxy)methyl chloride In N,N-dimethyl-formamide at -40℃; for 2h;
87%
Stage #1: 5-bromo-1H-pyrrolo[2,3-b]pyridine With sodium hydride In tetrahydrofuran at 0℃; for 0.5h; Inert atmosphere;
Stage #2: (2-trimethylethylsilylethoxy)methyl chloride In tetrahydrofuran at 20℃; for 2h; Inert atmosphere;
79%
2-bromoacetyl chloride
22118-09-8

2-bromoacetyl chloride

5-bromo-1H-pyrrolo[2,3-b]pyridine
183208-35-7

5-bromo-1H-pyrrolo[2,3-b]pyridine

2-bromo-1-(5-bromo-1H-pyrrolo[2,3-b]pyridin-3-yl)ethanone
875639-57-9

2-bromo-1-(5-bromo-1H-pyrrolo[2,3-b]pyridin-3-yl)ethanone

Conditions
ConditionsYield
Stage #1: 5-bromo-1H-pyrrolo[2,3-b]pyridine With aluminum (III) chloride In dichloromethane for 0.5h;
Stage #2: 2-bromoacetyl chloride In dichloromethane for 2h;
100%
Stage #1: 5-bromo-1H-pyrrolo[2,3-b]pyridine With aluminum (III) chloride In dichloromethane at 20℃; for 1h;
Stage #2: 2-bromoacetyl chloride In dichloromethane at 20℃;
92%
Stage #1: 5-bromo-1H-pyrrolo[2,3-b]pyridine With aluminum (III) chloride In dichloromethane for 0.5h; Inert atmosphere;
Stage #2: 2-bromoacetyl chloride In dichloromethane for 2h;
138 mg
5-bromo-1H-pyrrolo[2,3-b]pyridine
183208-35-7

5-bromo-1H-pyrrolo[2,3-b]pyridine

phenylboronic acid
98-80-6

phenylboronic acid

5-phenyl-1H-pyrrolo[2,3-b]pyridine
611205-38-0

5-phenyl-1H-pyrrolo[2,3-b]pyridine

Conditions
ConditionsYield
With potassium carbonate; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride In 1,4-dioxane; water at 80℃; for 22.5h; Suzuki Coupling;99%
With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium carbonate In 1,4-dioxane; water at 80℃; for 22.5h; Suzuki coupling;99%
With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium carbonate In 1,4-dioxane; water at 80℃; for 22.5h; Inert atmosphere;99%
With dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH2Cl2; potassium carbonate In 1,4-dioxane; water at 80℃; for 48h; Inert atmosphere;82%
With tetrakis(triphenylphosphine) palladium(0); potassium carbonate In ethanol; toluene at 120℃; for 24h; Suzuki-Miyaura Coupling; Inert atmosphere;62.93%
cyclopropanemethylamine
2516-47-4

cyclopropanemethylamine

5-bromo-1H-pyrrolo[2,3-b]pyridine
183208-35-7

5-bromo-1H-pyrrolo[2,3-b]pyridine

N-(cyclopropylmethyl)-1H-pyrrolo[2,3-b]pyridin-5-amine
1248587-76-9

N-(cyclopropylmethyl)-1H-pyrrolo[2,3-b]pyridin-5-amine

Conditions
ConditionsYield
With dicyclohexyl-(2′,4′,6′-triisopropyl-3,6-dimethoxy-[1,1′-biphenyl]-2-yl)phosphine; chloro[2-(dicyclohexylphosphino)-3,6-dimethoxy-2’,4’,6’-triisopropyl-1,1’-biphenyl] [2-(2-aminoethyl)phenyl]palladium(II); lithium hexamethyldisilazane In tetrahydrofuran at 65℃; for 4h; Inert atmosphere; Sealed vial;99%
cyclopropylcarbinyl bromide
7051-34-5

cyclopropylcarbinyl bromide

5-bromo-1H-pyrrolo[2,3-b]pyridine
183208-35-7

5-bromo-1H-pyrrolo[2,3-b]pyridine

Conditions
ConditionsYield
Stage #1: 5-bromo-1H-pyrrolo[2,3-b]pyridine With sodium hydride In N,N-dimethyl-formamide; mineral oil at 0℃; for 0.25h;
Stage #2: cyclopropylcarbinyl bromide In N,N-dimethyl-formamide; mineral oil at 0 - 20℃; for 2h;
99%
benzyl bromide
100-39-0

benzyl bromide

5-bromo-1H-pyrrolo[2,3-b]pyridine
183208-35-7

5-bromo-1H-pyrrolo[2,3-b]pyridine

1-benzyl-5-bromo-1H-pyrrolo[2,3-b] pyridine

1-benzyl-5-bromo-1H-pyrrolo[2,3-b] pyridine

Conditions
ConditionsYield
With tetra(n-butyl)ammonium hydrogensulfate; potassium hydroxide In acetone at 75℃; Inert atmosphere;99%
Stage #1: 5-bromo-1H-pyrrolo[2,3-b]pyridine With potassium tert-butylate In N,N-dimethyl acetamide for 0.25h; Cooling with ice;
Stage #2: benzyl bromide In N,N-dimethyl acetamide at 20℃; for 1h; Cooling with ice;
0.45 g
1-iodo-butane
542-69-8

1-iodo-butane

5-bromo-1H-pyrrolo[2,3-b]pyridine
183208-35-7

5-bromo-1H-pyrrolo[2,3-b]pyridine

5-bromo-1-butyl-1H-pyrrolo[2,3-b]pyridine

5-bromo-1-butyl-1H-pyrrolo[2,3-b]pyridine

Conditions
ConditionsYield
With tetra(n-butyl)ammonium hydrogensulfate; potassium hydroxide In acetone at 75℃; Inert atmosphere;99%
piperidine
110-89-4

piperidine

carbon monoxide
201230-82-2

carbon monoxide

5-bromo-1H-pyrrolo[2,3-b]pyridine
183208-35-7

5-bromo-1H-pyrrolo[2,3-b]pyridine

C13H15N3O

C13H15N3O

Conditions
ConditionsYield
With 2,2,6,6-tetramethyl-piperidine; dicobalt octacarbonyl In tert-Amyl alcohol under 1520.1 Torr; for 48h; Irradiation;99%
(2,3-difluorophenyl)acetyl chloride
808144-32-3

(2,3-difluorophenyl)acetyl chloride

5-bromo-1H-pyrrolo[2,3-b]pyridine
183208-35-7

5-bromo-1H-pyrrolo[2,3-b]pyridine

1-(5-bromo-1H-pyrrolo[2,3-b]pyridin-3-yl)-2-(2,3-difluoro-phenyl)-ethanone
849069-12-1

1-(5-bromo-1H-pyrrolo[2,3-b]pyridin-3-yl)-2-(2,3-difluoro-phenyl)-ethanone

Conditions
ConditionsYield
With aluminum (III) chloride In dichloromethane at 0 - 20℃; for 1.5h;98%
acetyl chloride
75-36-5

acetyl chloride

5-bromo-1H-pyrrolo[2,3-b]pyridine
183208-35-7

5-bromo-1H-pyrrolo[2,3-b]pyridine

1-(5-bromo-1H-pyrrolo[2,3-b]pyridin-3-yl)ethanone
866545-96-2

1-(5-bromo-1H-pyrrolo[2,3-b]pyridin-3-yl)ethanone

Conditions
ConditionsYield
With aluminum (III) chloride In dichloromethane at 20℃; Friedel Crafts acylation; Inert atmosphere;98%
aluminum (III) chloride In dichloromethane at 20℃; for 6h;93%
Stage #1: 5-bromo-1H-pyrrolo[2,3-b]pyridine With aluminum (III) chloride In dichloromethane at 20℃; for 1h;
Stage #2: acetyl chloride In dichloromethane for 5h;
93%
triisopropylsilyl chloride
13154-24-0

triisopropylsilyl chloride

5-bromo-1H-pyrrolo[2,3-b]pyridine
183208-35-7

5-bromo-1H-pyrrolo[2,3-b]pyridine

5-bromo-1-(triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridine
858116-66-2

5-bromo-1-(triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridine

Conditions
ConditionsYield
Stage #1: 5-bromo-1H-pyrrolo[2,3-b]pyridine With sodium hydride In 1,4-dioxane; N,N-dimethyl-formamide for 0.5h;
Stage #2: triisopropylsilyl chloride In 1,4-dioxane; N,N-dimethyl-formamide at 20℃;
97%
Stage #1: 5-bromo-1H-pyrrolo[2,3-b]pyridine With sodium hydride In tetrahydrofuran at 0℃; for 0.25h; Schlenk technique; Inert atmosphere;
Stage #2: triisopropylsilyl chloride In tetrahydrofuran at 0 - 20℃; Schlenk technique; Inert atmosphere;
94%
With potassium tert-butylate In tetrahydrofuran; N,N-dimethyl-formamide at 0 - 5℃; Solvent;93.8%
propyl bromide
106-94-5

propyl bromide

5-bromo-1H-pyrrolo[2,3-b]pyridine
183208-35-7

5-bromo-1H-pyrrolo[2,3-b]pyridine

5-bromo-1-propyl-1H-pyrrolo[2,3-b]pyridine
1440956-68-2

5-bromo-1-propyl-1H-pyrrolo[2,3-b]pyridine

Conditions
ConditionsYield
With sodium hydride In N,N-dimethyl acetamide at 20℃; for 2.5h;97%
Stage #1: 5-bromo-1H-pyrrolo[2,3-b]pyridine With sodium hydride In N,N-dimethyl acetamide; mineral oil at 20℃; for 0.5h;
Stage #2: propyl bromide In N,N-dimethyl acetamide; mineral oil for 2h;
97%
bis(pinacol)diborane
73183-34-3

bis(pinacol)diborane

5-bromo-1H-pyrrolo[2,3-b]pyridine
183208-35-7

5-bromo-1H-pyrrolo[2,3-b]pyridine

5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrolo[2,3-b]pyridine
754214-56-7

5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrolo[2,3-b]pyridine

Conditions
ConditionsYield
With dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH2Cl2; potassium acetate In 1,4-dioxane at 80℃; Inert atmosphere;95.9%
With dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH2Cl2; potassium acetate In 1,4-dioxane at 80℃; Inert atmosphere;95.9%
With potassium acetate; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH2Cl2 In 1,4-dioxane at 80℃; for 10h;94.2%
N-Methyl-N-phenethylamine
589-08-2

N-Methyl-N-phenethylamine

5-bromo-1H-pyrrolo[2,3-b]pyridine
183208-35-7

5-bromo-1H-pyrrolo[2,3-b]pyridine

N-methyl-N-phenethyl-1H-pyrrolo[2,3-b]pyridin-5-amine
1248587-68-9

N-methyl-N-phenethyl-1H-pyrrolo[2,3-b]pyridin-5-amine

Conditions
ConditionsYield
With RuPhos palladacycle; lithium hexamethyldisilazane; ruphos In tetrahydrofuran at 65℃; for 4h; Inert atmosphere; Sealed vial;95%

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