Dayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities
Cas:185836-75-3
Min.Order:1 Kilogram
FOB Price: $3.0
Type:Lab/Research institutions
inquiryWITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et
Cas:185836-75-3
Min.Order:1 Kilogram
FOB Price: $139.0 / 210.0
Type:Trading Company
inquiryEnglish alias: (R) -2-Methsuccinic acid 4-tert-butyl ester (R) -2-METHYLSUCCINIC ACID 4-TERT-BUTYL ESTER (R) -4-pert-butoxy-2-Methyl-4-oxobutanoic acid (2R) -2-Methylbutanedioic acid 4-tert-butyl ester (2R) -2-methyl-4- [(2-methylpropan-2-yl) oxy] -4
Cas:185836-75-3
Min.Order:5 Kilogram
FOB Price: $20.0 / 80.0
Type:Trading Company
inquiryName (2R)-2-Methylbutanedioic acid 4-tert-butyl ester Molecular Structure Molecular Formula C9H16O4 Molecular Weight 188.22 CAS Registry Number 185836-75-3 Ap
Cas:185836-75-3
Min.Order:1 Kilogram
FOB Price: $1.0
Type:Other
inquiryA substitute for perfluorooctanoic acid, mainly used as a surfactant, dispersant, additive, etc Appearance:White solid or Colorless liquid Purity:99.3 % We will ship the goods in a timely manner as required We can provide relevant documents acc
Cas:185836-75-3
Min.Order:4 Kilogram
Negotiable
Type:Lab/Research institutions
inquiryOur company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.O
Cas:185836-75-3
Min.Order:1 Kilogram
Negotiable
Type:Lab/Research institutions
inquiryWe are leading fine chemicals supplier in China with ISO certificate, Our main business covers the fields below: 1.Noble Metal Catalysts (Pt.Pd...) 2.Organic Phosphine Ligands (Tert-butyl-phosphine.Cyclohexyl-phosphine...) 3.OLED
Cas:185836-75-3
Min.Order:1 Kilogram
FOB Price: $3.0
Type:Lab/Research institutions
inquiryMy Company Changchun Artel Import and Export trade companyImport and Export Trade Co., Ltd.is located in Changchun, a national historical and cultural city, Jilin Province, China. It covers an area of 22,000 square meters, construction area
Cas:185836-75-3
Min.Order:20 Metric Ton
Negotiable
Type:Trading Company
inquiry1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer
Cas:185836-75-3
Min.Order:1 Metric Ton
FOB Price: $7.0 / 8.0
Type:Trading Company
inquiryAppearance:Solid powder Storage:Sealed,light and oxygen resistant Package:Foil bag or drum Application:Applied in dietary supplements,pharmaceutical or cosmeticeuticals Transportation:by sea or air Port:Beijing or Guangzhou Port
Cas:185836-75-3
Min.Order:0
Negotiable
Type:Other
inquiryLower price, sample is available,SDS test documents are available,large stock in warehouseAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:Fine chemical intermediates, used as the main raw material for the synthe
Cas:185836-75-3
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiryhigh quality Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea
Cas:185836-75-3
Min.Order:0
Negotiable
Type:Manufacturers
inquiry(2R)-2-Methylbutanedioic acid 4-tert-butyl esterAppearance:detailed see specifications Storage:Keep away of light, cool place Package:25kg/drum;200kg/drum Application:It is an important raw material and intermediate used in Organic Synthesis, Pharmac
Cas:185836-75-3
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiry(2R)-2-Methylbutanedioic acid 4-tert-butyl ester cas 185836-75-3Appearance:white crystalline powder Storage:Store in dry, dark and ventilated place Package:25KG drum Application:intermediate Transportation:by air, by sea, by express
Cas:185836-75-3
Min.Order:0
Negotiable
Type:Other
inquiryStock products, own laboratory Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai
Cas:185836-75-3
Min.Order:0
Negotiable
Type:Other
inquiryfactory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin
Cas:185836-75-3
Min.Order:0
Negotiable
Type:Trading Company
inquiryBest Seller, High Quality, Competitive Price, Fast Delivery, Quick ResponseAppearance:powder, or liquid Storage:Stored in room temperature, ventilated place Package:Bottle, barrel, cargo, container, etc. Application:Pharmaceuticals, intermediates, AP
Cas:185836-75-3
Min.Order:0
Negotiable
Type:Trading Company
inquiryOur mission is to provide high-quality and innovative products to our customers. By offering a broad range of products, custom synthesis and personalized services, Bide can help scientists speeding up their research in the chemical and pharmaceutical
Cas:185836-75-3
Min.Order:0
Negotiable
Type:Other
inquiry1.Professional synthesis laboratory and production base. 2.Strong synthesis team and service team. 3.Professional data management system. 4.We provide the professional test date and product information ,ex. HNMR ,CNMR,FNMR, HPLC/G
Cas:185836-75-3
Min.Order:10 Milligram
Negotiable
Type:Lab/Research institutions
inquiryPrice, service, company and transport advantage: 1. Best service, place of origin China, high quality, and reasonable price. 2. It's customers' right to choose the package (EMS, DHL, FEDEX, UPS). 3. It's customers' right
Cas:185836-75-3
Min.Order:0
Negotiable
Type:Trading Company
inquiry1. Production capacity: we have three production base with high-tech production equipment and instruments, equipped with professional production personnel, meet your requirements.2. Quality assurance: we have a first-class testing equipment and testi
Cas:185836-75-3
Min.Order:0
Negotiable
Type:Other
inquiry1 good quality, better price and bettter service;2 Timely delivery;3 100% refunded if parcel is not delivered or poor quality.We will try to satisfy you upon receipt of your reply. I hope that we can become a long-term cooperative partner. Applicatio
Cas:185836-75-3
Min.Order:0
Negotiable
Type:Trading Company
inquiryHigh Quality Best Price Storage:Store in dry, dark and ventilated place Application:Chemical Synthesis Intermediate
Debyesci is here who supplied several kinds of chemical products to global pharmaceutical, drug discovery, agrochemical and biotechnology industries for four yearsOur key scientific leadership team has gained experience in top research and developmen
Cas:185836-75-3
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiry(R)-2-METHYLSUCCINIC ACID 6-TERT-BUTYL ESTER
Cas:185836-75-3
Min.Order:0
Negotiable
Type:Trading Company
inquiry(4S)-3-((2R)-4-(tert-butoxy)-2-methyl-4-oxobutanoyl)-4-(phenylmethyl)-1,3-oxazolidin-2-one
(R)-3-tert-butyloxycarbonyl-2-methylpropanoic acid
Conditions | Yield |
---|---|
With lithium hydroxide; dihydrogen peroxide In tetrahydrofuran; water at 0℃; for 2h; Hydrolysis; | 95% |
With dihydrogen peroxide; lithium hydroxide In tetrahydrofuran; water at 0℃; for 2h; | 88% |
(S)-3-((R)-3-tert-Butoxycarbonyl-2-methyl-propionyl)-1-methyl-2-oxo-imidazolidine-4-carboxylic acid tert-butyl ester
(R)-3-tert-butyloxycarbonyl-2-methylpropanoic acid
Conditions | Yield |
---|---|
With lithium hydroxide In tetrahydrofuran; water for 3h; Ambient temperature; | 79% |
(4R,2'R)-3-(4'-tert-butoxy-4'-oxo-2'-methylbutanoyl)-4-iso-propyl-6,6-dimethyl-(1,3)-oxazinan-2-one
A
(R)-4-iso-propyl-6,6-dimethyl-(1,3)-oxazinan-2-one
B
(R)-3-tert-butyloxycarbonyl-2-methylpropanoic acid
Conditions | Yield |
---|---|
With lithium hydroxide; dihydrogen peroxide In tetrahydrofuran at 0 - 20℃; for 16h; | A 16 mg B 68% |
2-(RS)-methyl-1,4-butanedioic acid 4-(1,1-dimethylethyl) 1-methyl ester
A
(S)-4-(tert-butoxy)-2-methyl-4-oxobutanoic acid
B
(R)-3-tert-butyloxycarbonyl-2-methylpropanoic acid
Conditions | Yield |
---|---|
With sodium hydroxide; Alcalase In acetone for 18h; Hydrolysis; Title compound not separated from byproducts; |
bromoacetic acid tert-butyl ester
(R)-3-tert-butyloxycarbonyl-2-methylpropanoic acid
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1.1: KHMDS / tetrahydrofuran; toluene / 1 h / -78 °C 1.2: 74 percent / tetrahydrofuran; toluene / 2 h / -78 °C 2.1: 68 percent / aq. H2O2; LiOH / tetrahydrofuran / 16 h / 0 - 20 °C View Scheme | |
Multi-step reaction with 2 steps 1: 84 percent / NaN(SiMe3)2 / tetrahydrofuran / 3 h / -78 °C 2: 95 percent / H2O2; LiOH / tetrahydrofuran; H2O / 2 h / 0 °C View Scheme | |
Multi-step reaction with 2 steps 1.1: sodium hexamethyldisilazane / tetrahydrofuran / 1 h / -78 °C 1.2: 2.5 h / -78 °C 2.1: lithium hydroxide; dihydrogen peroxide / tetrahydrofuran; water / 2 h / 0 °C View Scheme |
2-methoxycarbonyl-2-methyl-succinic acid 4-tert-butyl ester 1-methyl ester
(R)-3-tert-butyloxycarbonyl-2-methylpropanoic acid
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: 33 percent / aq. lithium bromide / dimethylformamide / 8 h / 135 °C 2: alcalase; aq. NaOH / acetone / 18 h View Scheme |
2-[(R)-2-((S)-5-tert-Butoxycarbonyl-3-methyl-2-oxo-imidazolidin-1-yl)-1-methyl-2-oxo-ethyl]-malonic acid dibenzyl ester
(R)-3-tert-butyloxycarbonyl-2-methylpropanoic acid
Conditions | Yield |
---|---|
Multi-step reaction with 4 steps 1: 97 percent / H2 / Pd/C / methanol / 3 h / Ambient temperature 2: 86 percent / dimethylsulfoxide / 1 h / 100 °C 3: 91 percent / H2SO4 / CH2Cl2 / 12 h / Ambient temperature 4: 79 percent / LiOH*H2O / tetrahydrofuran; H2O / 3 h / Ambient temperature View Scheme |
(S)-3-((R)-3-Carboxy-2-methyl-propionyl)-1-methyl-2-oxo-imidazolidine-4-carboxylic acid tert-butyl ester
(R)-3-tert-butyloxycarbonyl-2-methylpropanoic acid
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: 91 percent / H2SO4 / CH2Cl2 / 12 h / Ambient temperature 2: 79 percent / LiOH*H2O / tetrahydrofuran; H2O / 3 h / Ambient temperature View Scheme |
2-[(R)-2-((S)-5-tert-Butoxycarbonyl-3-methyl-2-oxo-imidazolidin-1-yl)-1-methyl-2-oxo-ethyl]-malonic acid
(R)-3-tert-butyloxycarbonyl-2-methylpropanoic acid
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: 86 percent / dimethylsulfoxide / 1 h / 100 °C 2: 91 percent / H2SO4 / CH2Cl2 / 12 h / Ambient temperature 3: 79 percent / LiOH*H2O / tetrahydrofuran; H2O / 3 h / Ambient temperature View Scheme |
potassium tert-butylate
(R)-2-methyl-succinic acid 4-methyl ester
(R)-3-tert-butyloxycarbonyl-2-methylpropanoic acid
Conditions | Yield |
---|---|
With sulfuric acid In (2S)-N-methyl-1-phenylpropan-2-amine hydrate; hexane; water; tert-butyl alcohol |
(R)-2-methyl-succinic acid 4-methyl ester
(R)-3-tert-butyloxycarbonyl-2-methylpropanoic acid
citric acid
(R)-3-tert-butyloxycarbonyl-2-methylpropanoic acid
Conditions | Yield |
---|---|
With lithium hydroxide monohydrate; dihydrogen peroxide In tetrahydrofuran; water |
N-benzyl-N-methoxyamine
(R)-3-tert-butyloxycarbonyl-2-methylpropanoic acid
Conditions | Yield |
---|---|
With 1-hydroxy-7-aza-benzotriazole; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine In dichloromethane at 20℃; for 14h; Mechanism; Inert atmosphere; | 99% |
(R)-3-tert-butyloxycarbonyl-2-methylpropanoic acid
(R)-tert-butyl 4-hydroxy-3-methylbutanoate
Conditions | Yield |
---|---|
With dimethylsulfide borane complex In tetrahydrofuran for 24h; Reduction; | 97% |
With borane-THF In tetrahydrofuran at 20℃; | 85% |
With dimethylsulfide borane complex In tetrahydrofuran at 20℃; |
(R)-3-tert-butyloxycarbonyl-2-methylpropanoic acid
Conditions | Yield |
---|---|
With O-<[cyano(ethoxycarbonyl)methylene]amino>-1,1,3,3-tetramethyluronium tetrafluoroborate; N-ethyl-N,N-diisopropylamine In acetonitrile at 20℃; for 16h; | 95% |
(R)-3-tert-butyloxycarbonyl-2-methylpropanoic acid
Conditions | Yield |
---|---|
With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In pyridine at 20℃; for 4h; | 80% |
(R)-3-tert-butyloxycarbonyl-2-methylpropanoic acid
benzyl alcohol
Conditions | Yield |
---|---|
With diphenyl-phosphinic acid; triethylamine In toluene for 22h; Rearrangement; Curtius rearrangement; Heating; | 76% |
With diphenyl-phosphinic acid; triethylamine 1.) toluene, 80 deg C, 1 h, 2.) 80 deg C, 14 h; Yield given. Multistep reaction; |
(R)-3-tert-butyloxycarbonyl-2-methylpropanoic acid
Conditions | Yield |
---|---|
With O-<[cyano(ethoxycarbonyl)methylene]amino>-1,1,3,3-tetramethyluronium tetrafluoroborate; N-ethyl-N,N-diisopropylamine In acetonitrile at 20℃; for 16h; | 64% |
(R)-3-tert-butyloxycarbonyl-2-methylpropanoic acid
Conditions | Yield |
---|---|
With N-ethyl-N,N-diisopropylamine; HATU In N,N-dimethyl-formamide at 20℃; for 16h; | 48% |
tert-butylisonitrile
pivalaldehyde
(R)-3-tert-butyloxycarbonyl-2-methylpropanoic acid
Conditions | Yield |
---|---|
With ammonia In methanol Ambient temperature; |
(R)-3-tert-butyloxycarbonyl-2-methylpropanoic acid
(R)-4-Methoxymethoxy-2-methyl-butan-1-ol
Conditions | Yield |
---|---|
Multi-step reaction with 5 steps 1: BH3*Me2S / tetrahydrofuran / 20 °C 2: 2,6-lutidine / CH2Cl2 / 0 °C 3: LiAlH4 / tetrahydrofuran / 0 °C 4: (i-Pr)2NEt; DMAP / CH2Cl2 / 20 °C 5: TBAF / tetrahydrofuran / 20 °C View Scheme |
(R)-3-tert-butyloxycarbonyl-2-methylpropanoic acid
Conditions | Yield |
---|---|
Multi-step reaction with 4 steps 1: BH3*Me2S / tetrahydrofuran / 20 °C 2: 2,6-lutidine / CH2Cl2 / 0 °C 3: LiAlH4 / tetrahydrofuran / 0 °C 4: (i-Pr)2NEt; DMAP / CH2Cl2 / 20 °C View Scheme |
(R)-3-tert-butyloxycarbonyl-2-methylpropanoic acid
Conditions | Yield |
---|---|
Multi-step reaction with 6 steps 1: BH3*Me2S / tetrahydrofuran / 20 °C 2: 2,6-lutidine / CH2Cl2 / 0 °C 3: LiAlH4 / tetrahydrofuran / 0 °C 4: (i-Pr)2NEt; DMAP / CH2Cl2 / 20 °C 5: TBAF / tetrahydrofuran / 20 °C 6: DEAD; PPh3 / tetrahydrofuran / 20 °C View Scheme |
(R)-3-tert-butyloxycarbonyl-2-methylpropanoic acid
2-((R)-4-Methoxymethoxy-2-methyl-butane-1-sulfonyl)-benzothiazole
Conditions | Yield |
---|---|
Multi-step reaction with 7 steps 1: BH3*Me2S / tetrahydrofuran / 20 °C 2: 2,6-lutidine / CH2Cl2 / 0 °C 3: LiAlH4 / tetrahydrofuran / 0 °C 4: (i-Pr)2NEt; DMAP / CH2Cl2 / 20 °C 5: TBAF / tetrahydrofuran / 20 °C 6: DEAD; PPh3 / tetrahydrofuran / 20 °C 7: MCPBA; NaHCO3 / CH2Cl2 / 20 °C View Scheme |
(R)-3-tert-butyloxycarbonyl-2-methylpropanoic acid
Conditions | Yield |
---|---|
Multi-step reaction with 17 steps 1.1: BH3*Me2S / tetrahydrofuran / 20 °C 2.1: 2,6-lutidine / CH2Cl2 / 0 °C 3.1: LiAlH4 / tetrahydrofuran / 0 °C 4.1: (i-Pr)2NEt; DMAP / CH2Cl2 / 20 °C 5.1: TBAF / tetrahydrofuran / 20 °C 6.1: DEAD; PPh3 / tetrahydrofuran / 20 °C 7.1: MCPBA; NaHCO3 / CH2Cl2 / 20 °C 8.1: 79 percent / LHMDS / tetrahydrofuran / -78 - 20 °C 9.1: 39 percent / aq. HCl / methanol / 20 °C 10.1: H2 / PtO2 / methanol / 50 °C 11.1: imidazole / dimethylformamide / 20 °C 12.1: CSA / methanol / 20 °C 13.1: (COCl)2; DMSO / CH2Cl2 / -78 °C 13.2: Et3N / -78 - 20 °C 14.1: NaClO2; 2-methyl-2-butene; NaH2PO4 / 2-methyl-propan-2-ol; H2O / 20 °C 15.1: TBAF / tetrahydrofuran / 20 °C 16.1: Et3N / tetrahydrofuran / 0 °C 17.1: DMAP / benzene / 80 °C View Scheme |
(R)-3-tert-butyloxycarbonyl-2-methylpropanoic acid
(2S,3R,5S,6R)-2-((E)-(R)-5-Hydroxy-3-methyl-pent-1-enyl)-5-methoxy-6-methoxymethyl-2-methyl-tetrahydro-pyran-3-ol
Conditions | Yield |
---|---|
Multi-step reaction with 9 steps 1: BH3*Me2S / tetrahydrofuran / 20 °C 2: 2,6-lutidine / CH2Cl2 / 0 °C 3: LiAlH4 / tetrahydrofuran / 0 °C 4: (i-Pr)2NEt; DMAP / CH2Cl2 / 20 °C 5: TBAF / tetrahydrofuran / 20 °C 6: DEAD; PPh3 / tetrahydrofuran / 20 °C 7: MCPBA; NaHCO3 / CH2Cl2 / 20 °C 8: 79 percent / LHMDS / tetrahydrofuran / -78 - 20 °C 9: 39 percent / aq. HCl / methanol / 20 °C View Scheme |
(R)-3-tert-butyloxycarbonyl-2-methylpropanoic acid
Conditions | Yield |
---|---|
Multi-step reaction with 10 steps 1: BH3*Me2S / tetrahydrofuran / 20 °C 2: 2,6-lutidine / CH2Cl2 / 0 °C 3: LiAlH4 / tetrahydrofuran / 0 °C 4: (i-Pr)2NEt; DMAP / CH2Cl2 / 20 °C 5: TBAF / tetrahydrofuran / 20 °C 6: DEAD; PPh3 / tetrahydrofuran / 20 °C 7: MCPBA; NaHCO3 / CH2Cl2 / 20 °C 8: 79 percent / LHMDS / tetrahydrofuran / -78 - 20 °C 9: 39 percent / aq. HCl / methanol / 20 °C 10: H2 / PtO2 / methanol / 50 °C View Scheme |
(R)-3-tert-butyloxycarbonyl-2-methylpropanoic acid
(S)-5-((2S,3R,5S,6R)-3-Hydroxy-5-methoxy-6-methoxymethyl-2-methyl-tetrahydro-pyran-2-yl)-3-methyl-pentanoic acid
Conditions | Yield |
---|---|
Multi-step reaction with 15 steps 1.1: BH3*Me2S / tetrahydrofuran / 20 °C 2.1: 2,6-lutidine / CH2Cl2 / 0 °C 3.1: LiAlH4 / tetrahydrofuran / 0 °C 4.1: (i-Pr)2NEt; DMAP / CH2Cl2 / 20 °C 5.1: TBAF / tetrahydrofuran / 20 °C 6.1: DEAD; PPh3 / tetrahydrofuran / 20 °C 7.1: MCPBA; NaHCO3 / CH2Cl2 / 20 °C 8.1: 79 percent / LHMDS / tetrahydrofuran / -78 - 20 °C 9.1: 39 percent / aq. HCl / methanol / 20 °C 10.1: H2 / PtO2 / methanol / 50 °C 11.1: imidazole / dimethylformamide / 20 °C 12.1: CSA / methanol / 20 °C 13.1: (COCl)2; DMSO / CH2Cl2 / -78 °C 13.2: Et3N / -78 - 20 °C 14.1: NaClO2; 2-methyl-2-butene; NaH2PO4 / 2-methyl-propan-2-ol; H2O / 20 °C 15.1: TBAF / tetrahydrofuran / 20 °C View Scheme |
(R)-3-tert-butyloxycarbonyl-2-methylpropanoic acid
Conditions | Yield |
---|---|
Multi-step reaction with 13 steps 1.1: BH3*Me2S / tetrahydrofuran / 20 °C 2.1: 2,6-lutidine / CH2Cl2 / 0 °C 3.1: LiAlH4 / tetrahydrofuran / 0 °C 4.1: (i-Pr)2NEt; DMAP / CH2Cl2 / 20 °C 5.1: TBAF / tetrahydrofuran / 20 °C 6.1: DEAD; PPh3 / tetrahydrofuran / 20 °C 7.1: MCPBA; NaHCO3 / CH2Cl2 / 20 °C 8.1: 79 percent / LHMDS / tetrahydrofuran / -78 - 20 °C 9.1: 39 percent / aq. HCl / methanol / 20 °C 10.1: H2 / PtO2 / methanol / 50 °C 11.1: imidazole / dimethylformamide / 20 °C 12.1: CSA / methanol / 20 °C 13.1: (COCl)2; DMSO / CH2Cl2 / -78 °C 13.2: Et3N / -78 - 20 °C View Scheme |
(R)-3-tert-butyloxycarbonyl-2-methylpropanoic acid
(S)-5-[(2S,3R,5S,6R)-3-(tert-Butyl-dimethyl-silanyloxy)-5-methoxy-6-methoxymethyl-2-methyl-tetrahydro-pyran-2-yl]-3-methyl-pentan-1-ol
Conditions | Yield |
---|---|
Multi-step reaction with 12 steps 1: BH3*Me2S / tetrahydrofuran / 20 °C 2: 2,6-lutidine / CH2Cl2 / 0 °C 3: LiAlH4 / tetrahydrofuran / 0 °C 4: (i-Pr)2NEt; DMAP / CH2Cl2 / 20 °C 5: TBAF / tetrahydrofuran / 20 °C 6: DEAD; PPh3 / tetrahydrofuran / 20 °C 7: MCPBA; NaHCO3 / CH2Cl2 / 20 °C 8: 79 percent / LHMDS / tetrahydrofuran / -78 - 20 °C 9: 39 percent / aq. HCl / methanol / 20 °C 10: H2 / PtO2 / methanol / 50 °C 11: imidazole / dimethylformamide / 20 °C 12: CSA / methanol / 20 °C View Scheme |
(R)-3-tert-butyloxycarbonyl-2-methylpropanoic acid
tert-Butyl-[(2S,3R,5S,6R)-5-methoxy-2-((E)-(R)-5-methoxymethoxy-3-methyl-pent-1-enyl)-6-methoxymethyl-2-methyl-tetrahydro-pyran-3-yloxy]-dimethyl-silane
Conditions | Yield |
---|---|
Multi-step reaction with 8 steps 1: BH3*Me2S / tetrahydrofuran / 20 °C 2: 2,6-lutidine / CH2Cl2 / 0 °C 3: LiAlH4 / tetrahydrofuran / 0 °C 4: (i-Pr)2NEt; DMAP / CH2Cl2 / 20 °C 5: TBAF / tetrahydrofuran / 20 °C 6: DEAD; PPh3 / tetrahydrofuran / 20 °C 7: MCPBA; NaHCO3 / CH2Cl2 / 20 °C 8: 79 percent / LHMDS / tetrahydrofuran / -78 - 20 °C View Scheme |
(R)-3-tert-butyloxycarbonyl-2-methylpropanoic acid
Conditions | Yield |
---|---|
Multi-step reaction with 14 steps 1.1: BH3*Me2S / tetrahydrofuran / 20 °C 2.1: 2,6-lutidine / CH2Cl2 / 0 °C 3.1: LiAlH4 / tetrahydrofuran / 0 °C 4.1: (i-Pr)2NEt; DMAP / CH2Cl2 / 20 °C 5.1: TBAF / tetrahydrofuran / 20 °C 6.1: DEAD; PPh3 / tetrahydrofuran / 20 °C 7.1: MCPBA; NaHCO3 / CH2Cl2 / 20 °C 8.1: 79 percent / LHMDS / tetrahydrofuran / -78 - 20 °C 9.1: 39 percent / aq. HCl / methanol / 20 °C 10.1: H2 / PtO2 / methanol / 50 °C 11.1: imidazole / dimethylformamide / 20 °C 12.1: CSA / methanol / 20 °C 13.1: (COCl)2; DMSO / CH2Cl2 / -78 °C 13.2: Et3N / -78 - 20 °C 14.1: NaClO2; 2-methyl-2-butene; NaH2PO4 / 2-methyl-propan-2-ol; H2O / 20 °C View Scheme |
(R)-3-tert-butyloxycarbonyl-2-methylpropanoic acid
Conditions | Yield |
---|---|
Multi-step reaction with 11 steps 1: BH3*Me2S / tetrahydrofuran / 20 °C 2: 2,6-lutidine / CH2Cl2 / 0 °C 3: LiAlH4 / tetrahydrofuran / 0 °C 4: (i-Pr)2NEt; DMAP / CH2Cl2 / 20 °C 5: TBAF / tetrahydrofuran / 20 °C 6: DEAD; PPh3 / tetrahydrofuran / 20 °C 7: MCPBA; NaHCO3 / CH2Cl2 / 20 °C 8: 79 percent / LHMDS / tetrahydrofuran / -78 - 20 °C 9: 39 percent / aq. HCl / methanol / 20 °C 10: H2 / PtO2 / methanol / 50 °C 11: imidazole / dimethylformamide / 20 °C View Scheme |
(R)-3-tert-butyloxycarbonyl-2-methylpropanoic acid
Conditions | Yield |
---|---|
Multi-step reaction with 16 steps 1.1: BH3*Me2S / tetrahydrofuran / 20 °C 2.1: 2,6-lutidine / CH2Cl2 / 0 °C 3.1: LiAlH4 / tetrahydrofuran / 0 °C 4.1: (i-Pr)2NEt; DMAP / CH2Cl2 / 20 °C 5.1: TBAF / tetrahydrofuran / 20 °C 6.1: DEAD; PPh3 / tetrahydrofuran / 20 °C 7.1: MCPBA; NaHCO3 / CH2Cl2 / 20 °C 8.1: 79 percent / LHMDS / tetrahydrofuran / -78 - 20 °C 9.1: 39 percent / aq. HCl / methanol / 20 °C 10.1: H2 / PtO2 / methanol / 50 °C 11.1: imidazole / dimethylformamide / 20 °C 12.1: CSA / methanol / 20 °C 13.1: (COCl)2; DMSO / CH2Cl2 / -78 °C 13.2: Et3N / -78 - 20 °C 14.1: NaClO2; 2-methyl-2-butene; NaH2PO4 / 2-methyl-propan-2-ol; H2O / 20 °C 15.1: TBAF / tetrahydrofuran / 20 °C 16.1: Et3N / tetrahydrofuran / 0 °C View Scheme |
(R)-3-tert-butyloxycarbonyl-2-methylpropanoic acid
(3R)-4-(tert-butyl(dimethyl)silyloxy)-3-methylbutan-1-ol
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: BH3*Me2S / tetrahydrofuran / 20 °C 2: 2,6-lutidine / CH2Cl2 / 0 °C 3: LiAlH4 / tetrahydrofuran / 0 °C View Scheme |
(R)-3-tert-butyloxycarbonyl-2-methylpropanoic acid
tert-butyl (R)-4-tert-butyldimethylsilyloxy-3-methylbutanoate
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: BH3*Me2S / tetrahydrofuran / 20 °C 2: 2,6-lutidine / CH2Cl2 / 0 °C View Scheme |
(R)-3-tert-butyloxycarbonyl-2-methylpropanoic acid
(S)-2-methylpent-4-en-1-yl 4-methylbenzenesulfonate
Conditions | Yield |
---|---|
Multi-step reaction with 4 steps 1.1: 85 percent / BH3*THF / tetrahydrofuran / 20 °C 2.1: pyridine / CH2Cl2 / 0 °C 3.1: DIBAL / CH2Cl2; hexane / 0.5 h / -78 °C 4.1: NaHMDS / 1,2-dimethoxy-ethane; toluene / 20 °C 4.2: 1,2-dimethoxy-ethane; toluene / 20 °C View Scheme |
About|Contact|Cas|Product Name|Molecular|Country|Encyclopedia
Message|New Cas|MSDS|Service|Advertisement|CAS DataBase|Article Data|Manufacturers | Chemical Catalog
©2008 LookChem.com,License: ICP
NO.:Zhejiang16009103
complaints:service@lookchem.com Desktop View