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Dayang Chem (Hangzhou) Co.,Ltd.

Dayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities

(2R)-2-Methylbutanedioic acid 4-tert-butyl ester Manufacturer/High quality/Best price/In stock

Cas:185836-75-3

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Factory direct supply CAS 185836-75-3 with best quality

Cas:185836-75-3

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Hebei Nengqian Chemical Import and Export Co., LTD

English alias: (R) -2-Methsuccinic acid 4-tert-butyl ester (R) -2-METHYLSUCCINIC ACID 4-TERT-BUTYL ESTER (R) -4-pert-butoxy-2-Methyl-4-oxobutanoic acid (2R) -2-Methylbutanedioic acid 4-tert-butyl ester (2R) -2-methyl-4- [(2-methylpropan-2-yl) oxy] -4

(R)-2-METHYLSUCCINIC ACID 4-TERT-BUTYL ESTER 185836-75-3

Cas:185836-75-3

Min.Order:5 Kilogram

FOB Price: $20.0 / 80.0

Type:Trading Company

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Henan Sinotech Import&Export Corporation

Name (2R)-2-Methylbutanedioic acid 4-tert-butyl ester Molecular Structure Molecular Formula C9H16O4 Molecular Weight 188.22 CAS Registry Number 185836-75-3 Ap

(2R)-2-Methylbutanedioic acid 4-tert-butyl ester

Cas:185836-75-3

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Other

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SHANGHAI T&W PHARMACEUTICAL CO., LTD.

A substitute for perfluorooctanoic acid, mainly used as a surfactant, dispersant, additive, etc Appearance:White solid or Colorless liquid Purity:99.3 % We will ship the goods in a timely manner as required We can provide relevant documents acc

(R)-2-Methylsuccinic acid 4-tert-butyl ester

Cas:185836-75-3

Min.Order:4 Kilogram

Negotiable

Type:Lab/Research institutions

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Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.O

tianfu-chem_185836-75-3// (R)-2-METHYLSUCCINIC ACID 4-TERT-BUTYL ESTER

Cas:185836-75-3

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Henan Wentao Chemical Product Co., Ltd.

We are leading fine chemicals supplier in China with ISO certificate, Our main business covers the fields below: 1.Noble Metal Catalysts (Pt.Pd...) 2.Organic Phosphine Ligands (Tert-butyl-phosphine.Cyclohexyl-phosphine...) 3.OLED

(R)-2-METHYLSUCCINIC ACID 4-TERT-BUTYL ESTERCAS NO.: 185836-75-3

Cas:185836-75-3

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Changchun Artel lmport and Export trade company

My Company Changchun Artel Import and Export trade companyImport and Export Trade Co., Ltd.is located in Changchun, a national historical and cultural city, Jilin Province, China. It covers an area of 22,000 square meters, construction area

(2R)-2-Methylbutanedioic acid 4-tert-butyl ester Manufacturer CAS NO.185836-75-3

Cas:185836-75-3

Min.Order:20 Metric Ton

Negotiable

Type:Trading Company

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KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

(2R)-2-Methylbutanedioic acid 4-tert-butyl ester Manufacturer CAS NO.185836-75-3 CAS NO.185836-75-3

Cas:185836-75-3

Min.Order:1 Metric Ton

FOB Price: $7.0 / 8.0

Type:Trading Company

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Kono Chem Co.,Ltd

Appearance:Solid powder Storage:Sealed,light and oxygen resistant Package:Foil bag or drum Application:Applied in dietary supplements,pharmaceutical or cosmeticeuticals Transportation:by sea or air Port:Beijing or Guangzhou Port

(2R)-2-Methylbutanedioic acid 4-tert-butyl ester

Cas:185836-75-3

Min.Order:0

Negotiable

Type:Other

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GIHI CHEMICALS CO.,LIMITED

Lower price, sample is available,SDS test documents are available,large stock in warehouseAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:Fine chemical intermediates, used as the main raw material for the synthe

(R)-2-Methylsuccinic acid 4-tert-butyl ester

Cas:185836-75-3

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Henan Allgreen Chemical Co.,Ltd

high quality Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea

(R)-2-METHYLSUCCINIC ACID 4-TERT-BUTYL ESTER

Cas:185836-75-3

Min.Order:0

Negotiable

Type:Manufacturers

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Antimex Chemical Limied

(2R)-2-Methylbutanedioic acid 4-tert-butyl esterAppearance:detailed see specifications Storage:Keep away of light, cool place Package:25kg/drum;200kg/drum Application:It is an important raw material and intermediate used in Organic Synthesis, Pharmac

(2R)-2-Methylbutanedioic acid 4-tert-butyl ester

Cas:185836-75-3

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Fandachem Co.,Ltd

(2R)-2-Methylbutanedioic acid 4-tert-butyl ester cas 185836-75-3Appearance:white crystalline powder Storage:Store in dry, dark and ventilated place Package:25KG drum Application:intermediate Transportation:by air, by sea, by express

(2R)-2-Methylbutanedioic acid 4-tert-butyl ester cas 185836-75-3

Cas:185836-75-3

Min.Order:0

Negotiable

Type:Other

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Chemlyte Solutions

Stock products, own laboratory Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai

(R)-2-METHYLSUCCINIC ACID 4-TERT-BUTYL ESTER

Cas:185836-75-3

Min.Order:0

Negotiable

Type:Other

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ZHEJIANG JIUZHOU CHEM CO.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

(R)-2-METHYLSUCCINIC ACID 4-TERT-BUTYL ESTER

Cas:185836-75-3

Min.Order:0

Negotiable

Type:Trading Company

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LEAP CHEM Co., Ltd.

Best Seller, High Quality, Competitive Price, Fast Delivery, Quick ResponseAppearance:powder, or liquid Storage:Stored in room temperature, ventilated place Package:Bottle, barrel, cargo, container, etc. Application:Pharmaceuticals, intermediates, AP

(R)-2-METHYLSUCCINIC ACID 4-TERT-BUTYL ESTER

Cas:185836-75-3

Min.Order:0

Negotiable

Type:Trading Company

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Bide Pharmatech Ltd

Our mission is to provide high-quality and innovative products to our customers. By offering a broad range of products, custom synthesis and personalized services, Bide can help scientists speeding up their research in the chemical and pharmaceutical

(R)-4-(tert-Butoxy)-2-methyl-4-oxobutanoic acid

Cas:185836-75-3

Min.Order:0

Negotiable

Type:Other

inquiry

Amadis Chemical Co., Ltd.

1.Professional synthesis laboratory and production base. 2.Strong synthesis team and service team. 3.Professional data management system. 4.We provide the professional test date and product information ,ex. HNMR ,CNMR,FNMR, HPLC/G

(R)-4-(tert-Butoxy)-2-methyl-4-oxobutanoic acid

Cas:185836-75-3

Min.Order:10 Milligram

Negotiable

Type:Lab/Research institutions

inquiry

Jilin haofei import and export trade Co.,Ltd

Price, service, company and transport advantage: 1. Best service, place of origin China, high quality, and reasonable price. 2. It's customers' right to choose the package (EMS, DHL, FEDEX, UPS). 3. It's customers' right

Chemical Technology Co.,LTD

1. Production capacity: we have three production base with high-tech production equipment and instruments, equipped with professional production personnel, meet your requirements.2. Quality assurance: we have a first-class testing equipment and testi

(R)-2-METHYLSUCCINIC ACID 4-TERT-BUTYL ESTER

Cas:185836-75-3

Min.Order:0

Negotiable

Type:Other

inquiry

Shanghai PotentPharm Science and Technology Co.,Ltd

1 good quality, better price and bettter service;2 Timely delivery;3 100% refunded if parcel is not delivered or poor quality.We will try to satisfy you upon receipt of your reply. I hope that we can become a long-term cooperative partner. Applicatio

(R)-4-(tert-Butoxy)-2-Methyl-4-oxobutanoic acid

Cas:185836-75-3

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Finetech Industry Limited

High Quality Best Price Storage:Store in dry, dark and ventilated place Application:Chemical Synthesis Intermediate

FT-0774476

Cas:185836-75-3

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Debye Scientific

Debyesci is here who supplied several kinds of chemical products to global pharmaceutical, drug discovery, agrochemical and biotechnology industries for four yearsOur key scientific leadership team has gained experience in top research and developmen

(R)-2-Methylsuccinic acid4-tert-butylester

Cas:185836-75-3

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Mitsubishi Rayon Co., Ltd.

(R)-2-METHYLSUCCINIC ACID 6-TERT-BUTYL ESTER

(2R)-2-Methylbutanedioic acid 4-tert-butyl ester

Cas:185836-75-3

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Synthetic route

(4S)-3-((2R)-4-(tert-butoxy)-2-methyl-4-oxobutanoyl)-4-(phenylmethyl)-1,3-oxazolidin-2-one
202874-73-5

(4S)-3-((2R)-4-(tert-butoxy)-2-methyl-4-oxobutanoyl)-4-(phenylmethyl)-1,3-oxazolidin-2-one

(R)-3-tert-butyloxycarbonyl-2-methylpropanoic acid
185836-75-3

(R)-3-tert-butyloxycarbonyl-2-methylpropanoic acid

Conditions
ConditionsYield
With lithium hydroxide; dihydrogen peroxide In tetrahydrofuran; water at 0℃; for 2h; Hydrolysis;95%
With dihydrogen peroxide; lithium hydroxide In tetrahydrofuran; water at 0℃; for 2h;88%
(S)-3-((R)-3-tert-Butoxycarbonyl-2-methyl-propionyl)-1-methyl-2-oxo-imidazolidine-4-carboxylic acid tert-butyl ester
195829-02-8

(S)-3-((R)-3-tert-Butoxycarbonyl-2-methyl-propionyl)-1-methyl-2-oxo-imidazolidine-4-carboxylic acid tert-butyl ester

(R)-3-tert-butyloxycarbonyl-2-methylpropanoic acid
185836-75-3

(R)-3-tert-butyloxycarbonyl-2-methylpropanoic acid

Conditions
ConditionsYield
With lithium hydroxide In tetrahydrofuran; water for 3h; Ambient temperature;79%
(4R,2'R)-3-(4'-tert-butoxy-4'-oxo-2'-methylbutanoyl)-4-iso-propyl-6,6-dimethyl-(1,3)-oxazinan-2-one
908290-81-3

(4R,2'R)-3-(4'-tert-butoxy-4'-oxo-2'-methylbutanoyl)-4-iso-propyl-6,6-dimethyl-(1,3)-oxazinan-2-one

A

(R)-4-iso-propyl-6,6-dimethyl-(1,3)-oxazinan-2-one
908290-56-2

(R)-4-iso-propyl-6,6-dimethyl-(1,3)-oxazinan-2-one

B

(R)-3-tert-butyloxycarbonyl-2-methylpropanoic acid
185836-75-3

(R)-3-tert-butyloxycarbonyl-2-methylpropanoic acid

Conditions
ConditionsYield
With lithium hydroxide; dihydrogen peroxide In tetrahydrofuran at 0 - 20℃; for 16h;A 16 mg
B 68%
2-(RS)-methyl-1,4-butanedioic acid 4-(1,1-dimethylethyl) 1-methyl ester
82701-21-1

2-(RS)-methyl-1,4-butanedioic acid 4-(1,1-dimethylethyl) 1-methyl ester

A

(S)-4-(tert-butoxy)-2-methyl-4-oxobutanoic acid
182007-75-6

(S)-4-(tert-butoxy)-2-methyl-4-oxobutanoic acid

B

(R)-3-tert-butyloxycarbonyl-2-methylpropanoic acid
185836-75-3

(R)-3-tert-butyloxycarbonyl-2-methylpropanoic acid

Conditions
ConditionsYield
With sodium hydroxide; Alcalase In acetone for 18h; Hydrolysis; Title compound not separated from byproducts;
bromoacetic acid tert-butyl ester
5292-43-3

bromoacetic acid tert-butyl ester

(R)-3-tert-butyloxycarbonyl-2-methylpropanoic acid
185836-75-3

(R)-3-tert-butyloxycarbonyl-2-methylpropanoic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: KHMDS / tetrahydrofuran; toluene / 1 h / -78 °C
1.2: 74 percent / tetrahydrofuran; toluene / 2 h / -78 °C
2.1: 68 percent / aq. H2O2; LiOH / tetrahydrofuran / 16 h / 0 - 20 °C
View Scheme
Multi-step reaction with 2 steps
1: 84 percent / NaN(SiMe3)2 / tetrahydrofuran / 3 h / -78 °C
2: 95 percent / H2O2; LiOH / tetrahydrofuran; H2O / 2 h / 0 °C
View Scheme
Multi-step reaction with 2 steps
1.1: sodium hexamethyldisilazane / tetrahydrofuran / 1 h / -78 °C
1.2: 2.5 h / -78 °C
2.1: lithium hydroxide; dihydrogen peroxide / tetrahydrofuran; water / 2 h / 0 °C
View Scheme
2-methoxycarbonyl-2-methyl-succinic acid 4-tert-butyl ester 1-methyl ester
144843-09-4

2-methoxycarbonyl-2-methyl-succinic acid 4-tert-butyl ester 1-methyl ester

(R)-3-tert-butyloxycarbonyl-2-methylpropanoic acid
185836-75-3

(R)-3-tert-butyloxycarbonyl-2-methylpropanoic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 33 percent / aq. lithium bromide / dimethylformamide / 8 h / 135 °C
2: alcalase; aq. NaOH / acetone / 18 h
View Scheme
2-[(R)-2-((S)-5-tert-Butoxycarbonyl-3-methyl-2-oxo-imidazolidin-1-yl)-1-methyl-2-oxo-ethyl]-malonic acid dibenzyl ester
170704-11-7

2-[(R)-2-((S)-5-tert-Butoxycarbonyl-3-methyl-2-oxo-imidazolidin-1-yl)-1-methyl-2-oxo-ethyl]-malonic acid dibenzyl ester

(R)-3-tert-butyloxycarbonyl-2-methylpropanoic acid
185836-75-3

(R)-3-tert-butyloxycarbonyl-2-methylpropanoic acid

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: 97 percent / H2 / Pd/C / methanol / 3 h / Ambient temperature
2: 86 percent / dimethylsulfoxide / 1 h / 100 °C
3: 91 percent / H2SO4 / CH2Cl2 / 12 h / Ambient temperature
4: 79 percent / LiOH*H2O / tetrahydrofuran; H2O / 3 h / Ambient temperature
View Scheme
(S)-3-((R)-3-Carboxy-2-methyl-propionyl)-1-methyl-2-oxo-imidazolidine-4-carboxylic acid tert-butyl ester
195828-95-6

(S)-3-((R)-3-Carboxy-2-methyl-propionyl)-1-methyl-2-oxo-imidazolidine-4-carboxylic acid tert-butyl ester

(R)-3-tert-butyloxycarbonyl-2-methylpropanoic acid
185836-75-3

(R)-3-tert-butyloxycarbonyl-2-methylpropanoic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 91 percent / H2SO4 / CH2Cl2 / 12 h / Ambient temperature
2: 79 percent / LiOH*H2O / tetrahydrofuran; H2O / 3 h / Ambient temperature
View Scheme
2-[(R)-2-((S)-5-tert-Butoxycarbonyl-3-methyl-2-oxo-imidazolidin-1-yl)-1-methyl-2-oxo-ethyl]-malonic acid
195828-92-3

2-[(R)-2-((S)-5-tert-Butoxycarbonyl-3-methyl-2-oxo-imidazolidin-1-yl)-1-methyl-2-oxo-ethyl]-malonic acid

(R)-3-tert-butyloxycarbonyl-2-methylpropanoic acid
185836-75-3

(R)-3-tert-butyloxycarbonyl-2-methylpropanoic acid

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 86 percent / dimethylsulfoxide / 1 h / 100 °C
2: 91 percent / H2SO4 / CH2Cl2 / 12 h / Ambient temperature
3: 79 percent / LiOH*H2O / tetrahydrofuran; H2O / 3 h / Ambient temperature
View Scheme
potassium tert-butylate
865-47-4

potassium tert-butylate

(R)-2-methyl-succinic acid 4-methyl ester
23268-03-3, 80986-16-9, 111266-27-4, 81025-83-4

(R)-2-methyl-succinic acid 4-methyl ester

(R)-3-tert-butyloxycarbonyl-2-methylpropanoic acid
185836-75-3

(R)-3-tert-butyloxycarbonyl-2-methylpropanoic acid

Conditions
ConditionsYield
With sulfuric acid In (2S)-N-methyl-1-phenylpropan-2-amine hydrate; hexane; water; tert-butyl alcohol
(R)-2-methyl-succinic acid 4-methyl ester
23268-03-3, 80986-16-9, 111266-27-4, 81025-83-4

(R)-2-methyl-succinic acid 4-methyl ester

(R)-3-tert-butyloxycarbonyl-2-methylpropanoic acid
185836-75-3

(R)-3-tert-butyloxycarbonyl-2-methylpropanoic acid

aqueous sodium metabisulphite

aqueous sodium metabisulphite

(4S)-3-[(2R)-3-tert-butoxycarbonyl-2-methylpropionyl ]-4-isopropyloxazolidin-2-one

(4S)-3-[(2R)-3-tert-butoxycarbonyl-2-methylpropionyl ]-4-isopropyloxazolidin-2-one

citric acid
77-92-9

citric acid

(R)-3-tert-butyloxycarbonyl-2-methylpropanoic acid
185836-75-3

(R)-3-tert-butyloxycarbonyl-2-methylpropanoic acid

Conditions
ConditionsYield
With lithium hydroxide monohydrate; dihydrogen peroxide In tetrahydrofuran; water
N-benzyl-N-methoxyamine
20056-98-8

N-benzyl-N-methoxyamine

(R)-3-tert-butyloxycarbonyl-2-methylpropanoic acid
185836-75-3

(R)-3-tert-butyloxycarbonyl-2-methylpropanoic acid

C17H25NO4

C17H25NO4

Conditions
ConditionsYield
With 1-hydroxy-7-aza-benzotriazole; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine In dichloromethane at 20℃; for 14h; Mechanism; Inert atmosphere;99%
(R)-3-tert-butyloxycarbonyl-2-methylpropanoic acid
185836-75-3

(R)-3-tert-butyloxycarbonyl-2-methylpropanoic acid

(R)-tert-butyl 4-hydroxy-3-methylbutanoate
185836-76-4

(R)-tert-butyl 4-hydroxy-3-methylbutanoate

Conditions
ConditionsYield
With dimethylsulfide borane complex In tetrahydrofuran for 24h; Reduction;97%
With borane-THF In tetrahydrofuran at 20℃;85%
With dimethylsulfide borane complex In tetrahydrofuran at 20℃;
(S)-10-amino-2,3,5,10-tetrahydro-1H,11H-benzo[d]pyrazolo[1,2-a][1,2]diazepin-11-one hydrochloride

(S)-10-amino-2,3,5,10-tetrahydro-1H,11H-benzo[d]pyrazolo[1,2-a][1,2]diazepin-11-one hydrochloride

(R)-3-tert-butyloxycarbonyl-2-methylpropanoic acid
185836-75-3

(R)-3-tert-butyloxycarbonyl-2-methylpropanoic acid

tert-butyl (R)-3-methyl-4-oxo-4-(((S)-11-oxo-2,3,10,11-tetrahydro-1H,5H-benzo[d]pyrazolo[1,2-a][1,2]diazepin-10-yl)amino)butanoate

tert-butyl (R)-3-methyl-4-oxo-4-(((S)-11-oxo-2,3,10,11-tetrahydro-1H,5H-benzo[d]pyrazolo[1,2-a][1,2]diazepin-10-yl)amino)butanoate

Conditions
ConditionsYield
With O-<[cyano(ethoxycarbonyl)methylene]amino>-1,1,3,3-tetramethyluronium tetrafluoroborate; N-ethyl-N,N-diisopropylamine In acetonitrile at 20℃; for 16h;95%
(S)-10-amino-6-fluoro-2,3,5,10-tetrahydro-1H,11H-benzo[d]pyrazolo[1,2-a][1,2]diazepin-11-one hydrochloride

(S)-10-amino-6-fluoro-2,3,5,10-tetrahydro-1H,11H-benzo[d]pyrazolo[1,2-a][1,2]diazepin-11-one hydrochloride

(R)-3-tert-butyloxycarbonyl-2-methylpropanoic acid
185836-75-3

(R)-3-tert-butyloxycarbonyl-2-methylpropanoic acid

tert-butyl (R)-4-(((S)-6-fluoro-11-oxo-2,3,10,11-tetrahydro-1H,5H-benzo[d]pyrazolo[1,2-a][1,2]diazepin-10-yl)amino)-3-methyl-4-oxobutanoate

tert-butyl (R)-4-(((S)-6-fluoro-11-oxo-2,3,10,11-tetrahydro-1H,5H-benzo[d]pyrazolo[1,2-a][1,2]diazepin-10-yl)amino)-3-methyl-4-oxobutanoate

Conditions
ConditionsYield
With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In pyridine at 20℃; for 4h;80%
(R)-3-tert-butyloxycarbonyl-2-methylpropanoic acid
185836-75-3

(R)-3-tert-butyloxycarbonyl-2-methylpropanoic acid

benzyl alcohol
100-51-6

benzyl alcohol

tert-butyl (3R)-3-{[(benzyloxy)carbonyl]amino}butanoate

tert-butyl (3R)-3-{[(benzyloxy)carbonyl]amino}butanoate

Conditions
ConditionsYield
With diphenyl-phosphinic acid; triethylamine In toluene for 22h; Rearrangement; Curtius rearrangement; Heating;76%
With diphenyl-phosphinic acid; triethylamine 1.) toluene, 80 deg C, 1 h, 2.) 80 deg C, 14 h; Yield given. Multistep reaction;
(S)-10-amino-2,3-dihydro-1H,5H-benzo[d]pyrazolo[1,2-a][1,2]diazepine-5,11(10H)-dione hydrochloride

(S)-10-amino-2,3-dihydro-1H,5H-benzo[d]pyrazolo[1,2-a][1,2]diazepine-5,11(10H)-dione hydrochloride

(R)-3-tert-butyloxycarbonyl-2-methylpropanoic acid
185836-75-3

(R)-3-tert-butyloxycarbonyl-2-methylpropanoic acid

tert-butyl (R)-4-(((S)-5,11-dioxo-2,3,10,11-tetrahydro-1H,5H-benzo[d]pyrazolo[1,2-a][1,2]diazepin-10-yl)amino)-3-methyl-4-oxobutanoate

tert-butyl (R)-4-(((S)-5,11-dioxo-2,3,10,11-tetrahydro-1H,5H-benzo[d]pyrazolo[1,2-a][1,2]diazepin-10-yl)amino)-3-methyl-4-oxobutanoate

Conditions
ConditionsYield
With O-<[cyano(ethoxycarbonyl)methylene]amino>-1,1,3,3-tetramethyluronium tetrafluoroborate; N-ethyl-N,N-diisopropylamine In acetonitrile at 20℃; for 16h;64%
(S)-N-(3-cyclopropyl-2-(methylamino)propyl)-4-nitrobenzenesulfonamide

(S)-N-(3-cyclopropyl-2-(methylamino)propyl)-4-nitrobenzenesulfonamide

(R)-3-tert-butyloxycarbonyl-2-methylpropanoic acid
185836-75-3

(R)-3-tert-butyloxycarbonyl-2-methylpropanoic acid

tert-butyl (R)-4-(((S)-1-cyclopropyl-3-((4-nitrophenyl)sulfonamido)propan-2-yl)(methyl)amino)-3-methyl-4-oxobutanoate

tert-butyl (R)-4-(((S)-1-cyclopropyl-3-((4-nitrophenyl)sulfonamido)propan-2-yl)(methyl)amino)-3-methyl-4-oxobutanoate

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine; HATU In N,N-dimethyl-formamide at 20℃; for 16h;48%
tert-butylisonitrile
119072-55-8, 7188-38-7

tert-butylisonitrile

pivalaldehyde
630-19-3

pivalaldehyde

(R)-3-tert-butyloxycarbonyl-2-methylpropanoic acid
185836-75-3

(R)-3-tert-butyloxycarbonyl-2-methylpropanoic acid

(R)-N-(1-tert-Butylcarbamoyl-2,2-dimethyl-propyl)-3-methyl-succinamic acid tert-butyl ester

(R)-N-(1-tert-Butylcarbamoyl-2,2-dimethyl-propyl)-3-methyl-succinamic acid tert-butyl ester

Conditions
ConditionsYield
With ammonia In methanol Ambient temperature;
(R)-3-tert-butyloxycarbonyl-2-methylpropanoic acid
185836-75-3

(R)-3-tert-butyloxycarbonyl-2-methylpropanoic acid

(R)-4-Methoxymethoxy-2-methyl-butan-1-ol
881018-08-2

(R)-4-Methoxymethoxy-2-methyl-butan-1-ol

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1: BH3*Me2S / tetrahydrofuran / 20 °C
2: 2,6-lutidine / CH2Cl2 / 0 °C
3: LiAlH4 / tetrahydrofuran / 0 °C
4: (i-Pr)2NEt; DMAP / CH2Cl2 / 20 °C
5: TBAF / tetrahydrofuran / 20 °C
View Scheme
(R)-3-tert-butyloxycarbonyl-2-methylpropanoic acid
185836-75-3

(R)-3-tert-butyloxycarbonyl-2-methylpropanoic acid

tert-butyl-(4-methoxymethoxy-2-methyl-butoxy)-dimethyl-silane

tert-butyl-(4-methoxymethoxy-2-methyl-butoxy)-dimethyl-silane

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: BH3*Me2S / tetrahydrofuran / 20 °C
2: 2,6-lutidine / CH2Cl2 / 0 °C
3: LiAlH4 / tetrahydrofuran / 0 °C
4: (i-Pr)2NEt; DMAP / CH2Cl2 / 20 °C
View Scheme
(R)-3-tert-butyloxycarbonyl-2-methylpropanoic acid
185836-75-3

(R)-3-tert-butyloxycarbonyl-2-methylpropanoic acid

2-((R)-4-Methoxymethoxy-2-methyl-butylsulfanyl)-benzothiazole

2-((R)-4-Methoxymethoxy-2-methyl-butylsulfanyl)-benzothiazole

Conditions
ConditionsYield
Multi-step reaction with 6 steps
1: BH3*Me2S / tetrahydrofuran / 20 °C
2: 2,6-lutidine / CH2Cl2 / 0 °C
3: LiAlH4 / tetrahydrofuran / 0 °C
4: (i-Pr)2NEt; DMAP / CH2Cl2 / 20 °C
5: TBAF / tetrahydrofuran / 20 °C
6: DEAD; PPh3 / tetrahydrofuran / 20 °C
View Scheme
(R)-3-tert-butyloxycarbonyl-2-methylpropanoic acid
185836-75-3

(R)-3-tert-butyloxycarbonyl-2-methylpropanoic acid

2-((R)-4-Methoxymethoxy-2-methyl-butane-1-sulfonyl)-benzothiazole
881017-96-5

2-((R)-4-Methoxymethoxy-2-methyl-butane-1-sulfonyl)-benzothiazole

Conditions
ConditionsYield
Multi-step reaction with 7 steps
1: BH3*Me2S / tetrahydrofuran / 20 °C
2: 2,6-lutidine / CH2Cl2 / 0 °C
3: LiAlH4 / tetrahydrofuran / 0 °C
4: (i-Pr)2NEt; DMAP / CH2Cl2 / 20 °C
5: TBAF / tetrahydrofuran / 20 °C
6: DEAD; PPh3 / tetrahydrofuran / 20 °C
7: MCPBA; NaHCO3 / CH2Cl2 / 20 °C
View Scheme
(R)-3-tert-butyloxycarbonyl-2-methylpropanoic acid
185836-75-3

(R)-3-tert-butyloxycarbonyl-2-methylpropanoic acid

(2R,3S,4aR,8S,10aS)-3-Methoxy-2-methoxymethyl-8,10a-dimethyl-octahydro-1,5-dioxa-benzocycloocten-6-one

(2R,3S,4aR,8S,10aS)-3-Methoxy-2-methoxymethyl-8,10a-dimethyl-octahydro-1,5-dioxa-benzocycloocten-6-one

Conditions
ConditionsYield
Multi-step reaction with 17 steps
1.1: BH3*Me2S / tetrahydrofuran / 20 °C
2.1: 2,6-lutidine / CH2Cl2 / 0 °C
3.1: LiAlH4 / tetrahydrofuran / 0 °C
4.1: (i-Pr)2NEt; DMAP / CH2Cl2 / 20 °C
5.1: TBAF / tetrahydrofuran / 20 °C
6.1: DEAD; PPh3 / tetrahydrofuran / 20 °C
7.1: MCPBA; NaHCO3 / CH2Cl2 / 20 °C
8.1: 79 percent / LHMDS / tetrahydrofuran / -78 - 20 °C
9.1: 39 percent / aq. HCl / methanol / 20 °C
10.1: H2 / PtO2 / methanol / 50 °C
11.1: imidazole / dimethylformamide / 20 °C
12.1: CSA / methanol / 20 °C
13.1: (COCl)2; DMSO / CH2Cl2 / -78 °C
13.2: Et3N / -78 - 20 °C
14.1: NaClO2; 2-methyl-2-butene; NaH2PO4 / 2-methyl-propan-2-ol; H2O / 20 °C
15.1: TBAF / tetrahydrofuran / 20 °C
16.1: Et3N / tetrahydrofuran / 0 °C
17.1: DMAP / benzene / 80 °C
View Scheme
(R)-3-tert-butyloxycarbonyl-2-methylpropanoic acid
185836-75-3

(R)-3-tert-butyloxycarbonyl-2-methylpropanoic acid

(2S,3R,5S,6R)-2-((E)-(R)-5-Hydroxy-3-methyl-pent-1-enyl)-5-methoxy-6-methoxymethyl-2-methyl-tetrahydro-pyran-3-ol
881018-01-5

(2S,3R,5S,6R)-2-((E)-(R)-5-Hydroxy-3-methyl-pent-1-enyl)-5-methoxy-6-methoxymethyl-2-methyl-tetrahydro-pyran-3-ol

Conditions
ConditionsYield
Multi-step reaction with 9 steps
1: BH3*Me2S / tetrahydrofuran / 20 °C
2: 2,6-lutidine / CH2Cl2 / 0 °C
3: LiAlH4 / tetrahydrofuran / 0 °C
4: (i-Pr)2NEt; DMAP / CH2Cl2 / 20 °C
5: TBAF / tetrahydrofuran / 20 °C
6: DEAD; PPh3 / tetrahydrofuran / 20 °C
7: MCPBA; NaHCO3 / CH2Cl2 / 20 °C
8: 79 percent / LHMDS / tetrahydrofuran / -78 - 20 °C
9: 39 percent / aq. HCl / methanol / 20 °C
View Scheme
(R)-3-tert-butyloxycarbonyl-2-methylpropanoic acid
185836-75-3

(R)-3-tert-butyloxycarbonyl-2-methylpropanoic acid

(2S,3R,5S,6R)-2-((S)-5-Hydroxy-3-methyl-pentyl)-5-methoxy-6-methoxymethyl-2-methyl-tetrahydro-pyran-3-ol

(2S,3R,5S,6R)-2-((S)-5-Hydroxy-3-methyl-pentyl)-5-methoxy-6-methoxymethyl-2-methyl-tetrahydro-pyran-3-ol

Conditions
ConditionsYield
Multi-step reaction with 10 steps
1: BH3*Me2S / tetrahydrofuran / 20 °C
2: 2,6-lutidine / CH2Cl2 / 0 °C
3: LiAlH4 / tetrahydrofuran / 0 °C
4: (i-Pr)2NEt; DMAP / CH2Cl2 / 20 °C
5: TBAF / tetrahydrofuran / 20 °C
6: DEAD; PPh3 / tetrahydrofuran / 20 °C
7: MCPBA; NaHCO3 / CH2Cl2 / 20 °C
8: 79 percent / LHMDS / tetrahydrofuran / -78 - 20 °C
9: 39 percent / aq. HCl / methanol / 20 °C
10: H2 / PtO2 / methanol / 50 °C
View Scheme
(R)-3-tert-butyloxycarbonyl-2-methylpropanoic acid
185836-75-3

(R)-3-tert-butyloxycarbonyl-2-methylpropanoic acid

(S)-5-((2S,3R,5S,6R)-3-Hydroxy-5-methoxy-6-methoxymethyl-2-methyl-tetrahydro-pyran-2-yl)-3-methyl-pentanoic acid
881018-05-9

(S)-5-((2S,3R,5S,6R)-3-Hydroxy-5-methoxy-6-methoxymethyl-2-methyl-tetrahydro-pyran-2-yl)-3-methyl-pentanoic acid

Conditions
ConditionsYield
Multi-step reaction with 15 steps
1.1: BH3*Me2S / tetrahydrofuran / 20 °C
2.1: 2,6-lutidine / CH2Cl2 / 0 °C
3.1: LiAlH4 / tetrahydrofuran / 0 °C
4.1: (i-Pr)2NEt; DMAP / CH2Cl2 / 20 °C
5.1: TBAF / tetrahydrofuran / 20 °C
6.1: DEAD; PPh3 / tetrahydrofuran / 20 °C
7.1: MCPBA; NaHCO3 / CH2Cl2 / 20 °C
8.1: 79 percent / LHMDS / tetrahydrofuran / -78 - 20 °C
9.1: 39 percent / aq. HCl / methanol / 20 °C
10.1: H2 / PtO2 / methanol / 50 °C
11.1: imidazole / dimethylformamide / 20 °C
12.1: CSA / methanol / 20 °C
13.1: (COCl)2; DMSO / CH2Cl2 / -78 °C
13.2: Et3N / -78 - 20 °C
14.1: NaClO2; 2-methyl-2-butene; NaH2PO4 / 2-methyl-propan-2-ol; H2O / 20 °C
15.1: TBAF / tetrahydrofuran / 20 °C
View Scheme
(R)-3-tert-butyloxycarbonyl-2-methylpropanoic acid
185836-75-3

(R)-3-tert-butyloxycarbonyl-2-methylpropanoic acid

(S)-5-[(2S,3R,5S,6R)-3-(tert-Butyl-dimethyl-silanyloxy)-5-methoxy-6-methoxymethyl-2-methyl-tetrahydro-pyran-2-yl]-3-methyl-pentanal

(S)-5-[(2S,3R,5S,6R)-3-(tert-Butyl-dimethyl-silanyloxy)-5-methoxy-6-methoxymethyl-2-methyl-tetrahydro-pyran-2-yl]-3-methyl-pentanal

Conditions
ConditionsYield
Multi-step reaction with 13 steps
1.1: BH3*Me2S / tetrahydrofuran / 20 °C
2.1: 2,6-lutidine / CH2Cl2 / 0 °C
3.1: LiAlH4 / tetrahydrofuran / 0 °C
4.1: (i-Pr)2NEt; DMAP / CH2Cl2 / 20 °C
5.1: TBAF / tetrahydrofuran / 20 °C
6.1: DEAD; PPh3 / tetrahydrofuran / 20 °C
7.1: MCPBA; NaHCO3 / CH2Cl2 / 20 °C
8.1: 79 percent / LHMDS / tetrahydrofuran / -78 - 20 °C
9.1: 39 percent / aq. HCl / methanol / 20 °C
10.1: H2 / PtO2 / methanol / 50 °C
11.1: imidazole / dimethylformamide / 20 °C
12.1: CSA / methanol / 20 °C
13.1: (COCl)2; DMSO / CH2Cl2 / -78 °C
13.2: Et3N / -78 - 20 °C
View Scheme
(R)-3-tert-butyloxycarbonyl-2-methylpropanoic acid
185836-75-3

(R)-3-tert-butyloxycarbonyl-2-methylpropanoic acid

(S)-5-[(2S,3R,5S,6R)-3-(tert-Butyl-dimethyl-silanyloxy)-5-methoxy-6-methoxymethyl-2-methyl-tetrahydro-pyran-2-yl]-3-methyl-pentan-1-ol
881018-03-7

(S)-5-[(2S,3R,5S,6R)-3-(tert-Butyl-dimethyl-silanyloxy)-5-methoxy-6-methoxymethyl-2-methyl-tetrahydro-pyran-2-yl]-3-methyl-pentan-1-ol

Conditions
ConditionsYield
Multi-step reaction with 12 steps
1: BH3*Me2S / tetrahydrofuran / 20 °C
2: 2,6-lutidine / CH2Cl2 / 0 °C
3: LiAlH4 / tetrahydrofuran / 0 °C
4: (i-Pr)2NEt; DMAP / CH2Cl2 / 20 °C
5: TBAF / tetrahydrofuran / 20 °C
6: DEAD; PPh3 / tetrahydrofuran / 20 °C
7: MCPBA; NaHCO3 / CH2Cl2 / 20 °C
8: 79 percent / LHMDS / tetrahydrofuran / -78 - 20 °C
9: 39 percent / aq. HCl / methanol / 20 °C
10: H2 / PtO2 / methanol / 50 °C
11: imidazole / dimethylformamide / 20 °C
12: CSA / methanol / 20 °C
View Scheme
(R)-3-tert-butyloxycarbonyl-2-methylpropanoic acid
185836-75-3

(R)-3-tert-butyloxycarbonyl-2-methylpropanoic acid

tert-Butyl-[(2S,3R,5S,6R)-5-methoxy-2-((E)-(R)-5-methoxymethoxy-3-methyl-pent-1-enyl)-6-methoxymethyl-2-methyl-tetrahydro-pyran-3-yloxy]-dimethyl-silane
881017-98-7

tert-Butyl-[(2S,3R,5S,6R)-5-methoxy-2-((E)-(R)-5-methoxymethoxy-3-methyl-pent-1-enyl)-6-methoxymethyl-2-methyl-tetrahydro-pyran-3-yloxy]-dimethyl-silane

Conditions
ConditionsYield
Multi-step reaction with 8 steps
1: BH3*Me2S / tetrahydrofuran / 20 °C
2: 2,6-lutidine / CH2Cl2 / 0 °C
3: LiAlH4 / tetrahydrofuran / 0 °C
4: (i-Pr)2NEt; DMAP / CH2Cl2 / 20 °C
5: TBAF / tetrahydrofuran / 20 °C
6: DEAD; PPh3 / tetrahydrofuran / 20 °C
7: MCPBA; NaHCO3 / CH2Cl2 / 20 °C
8: 79 percent / LHMDS / tetrahydrofuran / -78 - 20 °C
View Scheme
(R)-3-tert-butyloxycarbonyl-2-methylpropanoic acid
185836-75-3

(R)-3-tert-butyloxycarbonyl-2-methylpropanoic acid

(S)-5-[(2S,3R,5S,6R)-3-(tert-Butyl-dimethyl-silanyloxy)-5-methoxy-6-methoxymethyl-2-methyl-tetrahydro-pyran-2-yl]-3-methyl-pentanoic acid

(S)-5-[(2S,3R,5S,6R)-3-(tert-Butyl-dimethyl-silanyloxy)-5-methoxy-6-methoxymethyl-2-methyl-tetrahydro-pyran-2-yl]-3-methyl-pentanoic acid

Conditions
ConditionsYield
Multi-step reaction with 14 steps
1.1: BH3*Me2S / tetrahydrofuran / 20 °C
2.1: 2,6-lutidine / CH2Cl2 / 0 °C
3.1: LiAlH4 / tetrahydrofuran / 0 °C
4.1: (i-Pr)2NEt; DMAP / CH2Cl2 / 20 °C
5.1: TBAF / tetrahydrofuran / 20 °C
6.1: DEAD; PPh3 / tetrahydrofuran / 20 °C
7.1: MCPBA; NaHCO3 / CH2Cl2 / 20 °C
8.1: 79 percent / LHMDS / tetrahydrofuran / -78 - 20 °C
9.1: 39 percent / aq. HCl / methanol / 20 °C
10.1: H2 / PtO2 / methanol / 50 °C
11.1: imidazole / dimethylformamide / 20 °C
12.1: CSA / methanol / 20 °C
13.1: (COCl)2; DMSO / CH2Cl2 / -78 °C
13.2: Et3N / -78 - 20 °C
14.1: NaClO2; 2-methyl-2-butene; NaH2PO4 / 2-methyl-propan-2-ol; H2O / 20 °C
View Scheme
(R)-3-tert-butyloxycarbonyl-2-methylpropanoic acid
185836-75-3

(R)-3-tert-butyloxycarbonyl-2-methylpropanoic acid

(2S,3R,5S,6R)-3-(tert-Butyl-dimethyl-silanyloxy)-2-[(S)-5-(tert-butyl-dimethyl-silanyloxy)-3-methyl-pentyl]-5-methoxy-6-methoxymethyl-2-methyl-tetrahydro-pyran

(2S,3R,5S,6R)-3-(tert-Butyl-dimethyl-silanyloxy)-2-[(S)-5-(tert-butyl-dimethyl-silanyloxy)-3-methyl-pentyl]-5-methoxy-6-methoxymethyl-2-methyl-tetrahydro-pyran

Conditions
ConditionsYield
Multi-step reaction with 11 steps
1: BH3*Me2S / tetrahydrofuran / 20 °C
2: 2,6-lutidine / CH2Cl2 / 0 °C
3: LiAlH4 / tetrahydrofuran / 0 °C
4: (i-Pr)2NEt; DMAP / CH2Cl2 / 20 °C
5: TBAF / tetrahydrofuran / 20 °C
6: DEAD; PPh3 / tetrahydrofuran / 20 °C
7: MCPBA; NaHCO3 / CH2Cl2 / 20 °C
8: 79 percent / LHMDS / tetrahydrofuran / -78 - 20 °C
9: 39 percent / aq. HCl / methanol / 20 °C
10: H2 / PtO2 / methanol / 50 °C
11: imidazole / dimethylformamide / 20 °C
View Scheme
(R)-3-tert-butyloxycarbonyl-2-methylpropanoic acid
185836-75-3

(R)-3-tert-butyloxycarbonyl-2-methylpropanoic acid

C22H29Cl3O7

C22H29Cl3O7

Conditions
ConditionsYield
Multi-step reaction with 16 steps
1.1: BH3*Me2S / tetrahydrofuran / 20 °C
2.1: 2,6-lutidine / CH2Cl2 / 0 °C
3.1: LiAlH4 / tetrahydrofuran / 0 °C
4.1: (i-Pr)2NEt; DMAP / CH2Cl2 / 20 °C
5.1: TBAF / tetrahydrofuran / 20 °C
6.1: DEAD; PPh3 / tetrahydrofuran / 20 °C
7.1: MCPBA; NaHCO3 / CH2Cl2 / 20 °C
8.1: 79 percent / LHMDS / tetrahydrofuran / -78 - 20 °C
9.1: 39 percent / aq. HCl / methanol / 20 °C
10.1: H2 / PtO2 / methanol / 50 °C
11.1: imidazole / dimethylformamide / 20 °C
12.1: CSA / methanol / 20 °C
13.1: (COCl)2; DMSO / CH2Cl2 / -78 °C
13.2: Et3N / -78 - 20 °C
14.1: NaClO2; 2-methyl-2-butene; NaH2PO4 / 2-methyl-propan-2-ol; H2O / 20 °C
15.1: TBAF / tetrahydrofuran / 20 °C
16.1: Et3N / tetrahydrofuran / 0 °C
View Scheme
(R)-3-tert-butyloxycarbonyl-2-methylpropanoic acid
185836-75-3

(R)-3-tert-butyloxycarbonyl-2-methylpropanoic acid

(3R)-4-(tert-butyl(dimethyl)silyloxy)-3-methylbutan-1-ol
147915-55-7

(3R)-4-(tert-butyl(dimethyl)silyloxy)-3-methylbutan-1-ol

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: BH3*Me2S / tetrahydrofuran / 20 °C
2: 2,6-lutidine / CH2Cl2 / 0 °C
3: LiAlH4 / tetrahydrofuran / 0 °C
View Scheme
(R)-3-tert-butyloxycarbonyl-2-methylpropanoic acid
185836-75-3

(R)-3-tert-butyloxycarbonyl-2-methylpropanoic acid

tert-butyl (R)-4-tert-butyldimethylsilyloxy-3-methylbutanoate
306739-86-6

tert-butyl (R)-4-tert-butyldimethylsilyloxy-3-methylbutanoate

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: BH3*Me2S / tetrahydrofuran / 20 °C
2: 2,6-lutidine / CH2Cl2 / 0 °C
View Scheme
(R)-3-tert-butyloxycarbonyl-2-methylpropanoic acid
185836-75-3

(R)-3-tert-butyloxycarbonyl-2-methylpropanoic acid

(S)-2-methylpent-4-en-1-yl 4-methylbenzenesulfonate
132857-79-5

(S)-2-methylpent-4-en-1-yl 4-methylbenzenesulfonate

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: 85 percent / BH3*THF / tetrahydrofuran / 20 °C
2.1: pyridine / CH2Cl2 / 0 °C
3.1: DIBAL / CH2Cl2; hexane / 0.5 h / -78 °C
4.1: NaHMDS / 1,2-dimethoxy-ethane; toluene / 20 °C
4.2: 1,2-dimethoxy-ethane; toluene / 20 °C
View Scheme

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