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Hangzhou Think Chemical Co. Ltd

(3R)-Tetrahydrofuran-3-yl 4-methylbenzenesulfonate CAS No.:219823-47-9 HANGZHOU THINK CHEMICAL CO., LTD. (THINKCHEM) is an integrative corporation of trade, research and contract manufacture. With about ten years of business experiences on

Enke Pharma-tech Co.,Ltd. (Cangzhou, China )

Cangzhou Enke Pharma Tech Co.,ltd. is located in Cangzhou City, Hebei province ,where is a famous petroleum chemical industry city in China. Enke Pharma a high-tech enterprise ,and we are dedicated to developing and manufacturing new ap

(3R)-Tetrahydrofuran-3-yl 4-methylbenzenesulfonate

Cas:219823-47-9

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Manufacturers

inquiry

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

(3R)-Tetrahydrofuran-3-yl 4-methylbenzenesulfonate

Cas:219823-47-9

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Pharmaceutical Grade CAS 219823-47-9 with competitive price

Cas:219823-47-9

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

inquiry

Triumph International Development Limilted

Appearance:white or light yellow crystalline powder Storage:Store in a cool,dry place and keep away from direct strong light Package:As customer request Application:Used for research and industrial manufacture. Transportation:By

(R)-tetrahydrofuran-3-yl 4-methylbenzenesulfonate

Cas:219823-47-9

Min.Order:100 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Massive Chemical Technology Co., Ltd.

Massive Chemical is certified with ISO9001 and ISO14001 manufacturer for this product. We will offer all documents as requirement for the materials which includes, Certificate of Analysis, Material Safety Data Sheet, and Method of Analysis and

(R)-3-(p-toluenesulfonyl) oxytetrahydrofuran/High quality/Best price

Cas:219823-47-9

Min.Order:1 Gram

FOB Price: $1.0

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

R)-3-(p-toluenesulfonyl) oxytetrahydrofuran

Cas:219823-47-9

Min.Order:10 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Tianfu Chemical Co., Ltd.

R)-3-(p-toluenesulfonyl) oxytetrahydrofuran; (R)-tetrahydrofuran-3-yl 4-methylbenzenesulfonate; (R)-Toluene-4-sulfonic acid tetrahydrofuran-3-yl ester; (3R)-Tetrahydrofuran-3- Yl 4-meth

(R)-3-(p-toluenesulfonyl) oxytetrahydrofuran

Cas:219823-47-9

Min.Order:100 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Huarong Pharm Co., Ltd.

Hangzhou Huarong Pharm Co., Ltd.established since 2006 , has been actively developing specialty products for Finished Dosages, APIs, Intermediates, and Fine chemicals markets in North America, Europe, Korea, Japan, Mid-East and all over the World. Hu

R)-3-(p-toluenesulfonyl) oxytetrahydrofuran

Cas:219823-47-9

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Nanjing Fred Technology Co.,Ltd.

(R)-3-(p-toluenesulfonyl) oxytetrahydrofuran is one of the most competitive products in our company. We can supply it with good quality and best price. Appearance:powder Storage:2-8°C Package:Kilograms/MT Application:Pharmaceutical field Transportat

(R)-3-(p-toluenesulfonyl) oxytetrahydrofuran

Cas:219823-47-9

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Bluecrystal chem-union

We are a Union of chemistry in China, consists of chemists,engineers, laboratories,factories in China. We organize surplus capacity of R&D and production as well as custom synthesis for chemical products and chemical business project. We are supp

R)-3-(p-toluenesulfonyl) oxytetrahydrofuran

Cas:219823-47-9

Min.Order:1 Metric Ton

FOB Price: $1.0

Type:Trading Company

inquiry

Sinoway Industrial Co., Ltd.

Why is SINOWAY: 1) Specialized in pharmaceutical and healthcare industrial for 37 years. 2) ISO 9001:2015 & SGS audited supplier . 3) Accept various payment terms : T.T 30-60 days. 4) We have warehouse in USA with quickly shipment . 5) We c

(R)-3-(p-toluenesulfonyl) oxytetrahydrofuran

Cas:219823-47-9

Min.Order:0 Kilogram

Negotiable

Type:Trading Company

inquiry

Hubei Taiho Chemical Co.,LTD

TAIHO Unique Advantages:1.We're factory2.Free samples available3.Commodity inspection can be done4.ISO9001,Kosher certifications5.10 years experiences Storage:Store in cool &dry place Package:aluminium foil bag/fiber can/plastic drum Application:comp

(3R)-Tetrahydrofuran-3-yl 4-methylbenzenesulfonate

Cas:219823-47-9

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Koning Pharmchem Co., Ltd.

KONING PHARMCHEM CO., LTD. has committed itself to a strategy of providing a unique service for companies involved in the manufacture of pharmaceuticals, healthcare products, food, cosmetics and other fine chemicals. Our products including but not li

(3R)-Tetrahydrofuran-3-yl 4-methylbenzenesulfonate

Cas:219823-47-9

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Antimex Chemical Limied

Our own factory produces direct sales with absolute price advantage Application:Pharmaceutical industry Transportation:By sea Port:Shanghai/tianjin

R)-3-(p-toluenesulfonyl) oxytetrahydrofuran

Cas:219823-47-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Guangdong Juda Chemical Industrial Co.,Limited

Factory supply high purity low priceAppearance:solid or liquid Storage:sealed in cool and dry place Package:As customer's requested Application:Pharma Intermediate Transportation:by courier/air/sea Port:Any port in China

R)-3-(p-toluenesulfonyl) oxytetrahydrofuran CAS No.219823-47-9

Cas:219823-47-9

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Chemsigma International Co.,Ltd.

bulk productionChemsigma International Co.,Ltd. is a chemical manufacturer, specialize in custom synthesis and organic chemical manufacturing for overseas customers, in the field of API, pharmaceutical intermediates, chemical intermediates, fine chem

(3R)-Tetrahydrofuran-3-yl 4-Methylbenzenesulfonate

Cas:219823-47-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Wuhan Circle Star Chem-medical Technology co.,Ltd.

good quality, competitive price, thoughtful after sale serviceAppearance:white powder Storage:Keep it in dry,shady and cool place Package:25kg,50kg,180kg,200kg,250kg,1000kg,customization Application:Pharma;Industry;Agricultural;chemical reaserch Tran

toluene-4-sulfonic acid (R)-(tetrahydro-furan- 3-yl) ester

Cas:219823-47-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Scochem Technology Co., Ltd.

High quality suppliers Application:healing drugs

R)-3-(p-toluenesulfonyl) oxytetrahydrofuran

Cas:219823-47-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

ZHEJIANG JIUZHOU CHEM CO.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

R)-3-(p-toluenesulfonyl) oxytetrahydrofuran

Cas:219823-47-9

Min.Order:0

Negotiable

Type:Trading Company

inquiry

LEAP CHEM Co., Ltd.

Best Seller, High Quality, Competitive Price, Fast Delivery, Quick ResponseAppearance:powder, or liquid Storage:Stored in room temperature, ventilated place Package:Bottle, barrel, cargo, container, etc. Application:Pharmaceuticals, intermediates, AP

TETRAHYDROFURAN-3-YL-(R)-TOLUENE-4-SULPHONATE

Cas:219823-47-9

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Hunan Zhongqi Pharmaceutical Co., Ltd

Hunan Zhong Qi Pharmaceutical Co.,Ltd. Yueyang branch,is a pharmaceutical company manufacturing and supplying APIs and intermediates. Our products include twelve (12) SFDA approved APIs (Adenosine Cyclophosphate,Calcium Dibutyacyladenosine Cyclophosp

(3R)-Tetrahydrofuran-3-yl 4-methylbenzenesulfonate

Cas:219823-47-9

Min.Order:0

Negotiable

Type:

inquiry

Synova( Tianjin ) Chemical Technology Co,.Ltd

The company have effective management team, professional technical R & D personnel, the service spirit of customer oriented. We have long-term cooperation with famous domestic manufacturer, and excellent customer resources overseas. We are skilled in

R)-3-(p-toluenesulfonyl) oxytetrahydrofuran

Cas:219823-47-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

coolpharm Ltd

Known for its best quality and competitve price, this chemicals we offered is widely appreciated by our customers.Appearance:yellow to white solid Storage:keep sealed and keep from direct light Package:According client's requirements Application:Phar

(3R)-OXOLAN-3-YL 4-METHYLBENZENE-1-SULFONATE

Cas:219823-47-9

Min.Order:0

Negotiable

Type:Other

inquiry

SINCERITY ENTERPRISE LTD

Sincerity Enterprise Ltd has much experience focused on providing integrated development and manufacturing service to Pharmaceutical,Additives,Fine Chemicals, Electronic chemicals and so on.We owned independent research and development center, with m

(R)-tetrahydrofuran-3-yl 4-methylbenzenesulfonate

Cas:219823-47-9

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Alchemist-pharm chemical Technology Co. Ltd.

R & D enterprises have their own stock in stock Package:1kg Application:pharmaceutical intermediates

219823-47-9

Cas:219823-47-9

Min.Order:0

Negotiable

Type:Trading Company

inquiry

NovaChemistry

high purity Application:Drug intermediates Materials intermediates and active molecules

(R)-tetrahydrofuran-3-yl 4-methylbenzenesulfonate

Cas:219823-47-9

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Synthetic route

(R)-3-Hydroxytetrahydrofuran
86087-24-3

(R)-3-Hydroxytetrahydrofuran

p-toluenesulfonyl chloride
98-59-9

p-toluenesulfonyl chloride

(R)-tetrahydrofuran-3-yl 4-methylbenzenesulfonate
219823-47-9

(R)-tetrahydrofuran-3-yl 4-methylbenzenesulfonate

Conditions
ConditionsYield
With pyridine In dichloromethane at 0 - 20℃; for 18h; Inert atmosphere;100%
With potassium iodide; silver(l) oxide In dichloromethane at 40℃;89%
Stage #1: (R)-3-Hydroxytetrahydrofuran With trimethylamine hydrochloride; triethylamine In dichloromethane at 20℃; for 0.333333h;
Stage #2: p-toluenesulfonyl chloride In dichloromethane at 20℃;
83%
4'-hydroxy-biphenyl-4-carboxylic acid (R)-1-methyl-heptyl ester
121687-76-1

4'-hydroxy-biphenyl-4-carboxylic acid (R)-1-methyl-heptyl ester

(R)-tetrahydrofuran-3-yl 4-methylbenzenesulfonate
219823-47-9

(R)-tetrahydrofuran-3-yl 4-methylbenzenesulfonate

4'-[(R)-(tetrahydro-furan-3-yl)oxy]-biphenyl-4-carboxylic acid (R)-1-methyl-heptyl ester
1610514-57-2

4'-[(R)-(tetrahydro-furan-3-yl)oxy]-biphenyl-4-carboxylic acid (R)-1-methyl-heptyl ester

Conditions
ConditionsYield
With caesium carbonate In N,N-dimethyl-formamide at 60℃; for 4h;91.7%
4-ethoxycarbonylpyrazole
37622-90-5

4-ethoxycarbonylpyrazole

(R)-tetrahydrofuran-3-yl 4-methylbenzenesulfonate
219823-47-9

(R)-tetrahydrofuran-3-yl 4-methylbenzenesulfonate

C10H14N2O3
1589005-67-3

C10H14N2O3

Conditions
ConditionsYield
With caesium carbonate In N,N-dimethyl-formamide at 80℃; for 14h;91%
4-bromo-phenol
106-41-2

4-bromo-phenol

(R)-tetrahydrofuran-3-yl 4-methylbenzenesulfonate
219823-47-9

(R)-tetrahydrofuran-3-yl 4-methylbenzenesulfonate

(S)-3-(4-bromophenoxy)tetrahydrofuran
857854-82-1

(S)-3-(4-bromophenoxy)tetrahydrofuran

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 100℃; for 10h;90.1%
With potassium carbonate In N,N-dimethyl-formamide at 85℃; for 15h;
(2-chloro-5-iodophenyl)(4-hydroxyphenyl)methanone
1459754-40-5

(2-chloro-5-iodophenyl)(4-hydroxyphenyl)methanone

(R)-tetrahydrofuran-3-yl 4-methylbenzenesulfonate
219823-47-9

(R)-tetrahydrofuran-3-yl 4-methylbenzenesulfonate

(S)-(2-chloro-5-iodophenyl)(4-((tetrahydrofuran-3-yl)oxy)phenyl)methanone
915095-87-3

(S)-(2-chloro-5-iodophenyl)(4-((tetrahydrofuran-3-yl)oxy)phenyl)methanone

Conditions
ConditionsYield
With potassium carbonate; potassium iodide In acetonitrile at 50 - 55℃;87%
(2R,3R,4R,5S,6S)-2-(acetoxymethyl)-6-(4-chloro-3-(4-hydroxybenzyl)phenyl)tetrahydro-2H-pyran-3,4,5-triyl triacetate
1079083-63-8

(2R,3R,4R,5S,6S)-2-(acetoxymethyl)-6-(4-chloro-3-(4-hydroxybenzyl)phenyl)tetrahydro-2H-pyran-3,4,5-triyl triacetate

(R)-tetrahydrofuran-3-yl 4-methylbenzenesulfonate
219823-47-9

(R)-tetrahydrofuran-3-yl 4-methylbenzenesulfonate

(2R,3R,4R,5S,6S)-2-(acetoxymethyl)-6-(4-chloro-3-(4-(((S)-tetrahydrofuran-3-yl)oxy)benzyl)phenyl)tetrahydro-2H-pyran-3,4,5-trityl triacetate

(2R,3R,4R,5S,6S)-2-(acetoxymethyl)-6-(4-chloro-3-(4-(((S)-tetrahydrofuran-3-yl)oxy)benzyl)phenyl)tetrahydro-2H-pyran-3,4,5-trityl triacetate

Conditions
ConditionsYield
With potassium carbonate In acetonitrile at 20℃;87%
(R)-tert-butyl (2-(5-(2-fluoro-3-hydroxyphenyl)-3-(2-fluoro-6-(trifluoromethyl)benzyl)-4-methyl-2,6-dioxo-2,3-dihydropyrimidine-1(6H)-yl)-1-phenylethyl)carbamate

(R)-tert-butyl (2-(5-(2-fluoro-3-hydroxyphenyl)-3-(2-fluoro-6-(trifluoromethyl)benzyl)-4-methyl-2,6-dioxo-2,3-dihydropyrimidine-1(6H)-yl)-1-phenylethyl)carbamate

(R)-tetrahydrofuran-3-yl 4-methylbenzenesulfonate
219823-47-9

(R)-tetrahydrofuran-3-yl 4-methylbenzenesulfonate

tert-butyl ((R)-2-(5-(2-fluoro-3-(((S)-tetrahydrofuran-3-yl)oxy)phenyl)-3-(2-fluoro- 6-(trifluoromethyl)benzyl)-4-methyl-2,6-dioxo-2,3-dihydropyrimidine-1(6H)-yl)-1-phenylethyl)carbamate

tert-butyl ((R)-2-(5-(2-fluoro-3-(((S)-tetrahydrofuran-3-yl)oxy)phenyl)-3-(2-fluoro- 6-(trifluoromethyl)benzyl)-4-methyl-2,6-dioxo-2,3-dihydropyrimidine-1(6H)-yl)-1-phenylethyl)carbamate

Conditions
ConditionsYield
With caesium carbonate In N,N-dimethyl-formamide at 70℃; for 12h;87%
C28H30O11
903566-68-7

C28H30O11

(R)-tetrahydrofuran-3-yl 4-methylbenzenesulfonate
219823-47-9

(R)-tetrahydrofuran-3-yl 4-methylbenzenesulfonate

1,1-anhydro-1-C-[5-(4-((S)-tetrahydrofuran-3-yloxy)-phenyl)-methyl-2-(hydroxymethyl)phenyl]-2,3,4,6-tetra-O-acetyl-β-D-glucopyranose

1,1-anhydro-1-C-[5-(4-((S)-tetrahydrofuran-3-yloxy)-phenyl)-methyl-2-(hydroxymethyl)phenyl]-2,3,4,6-tetra-O-acetyl-β-D-glucopyranose

Conditions
ConditionsYield
With caesium carbonate In N,N-dimethyl-formamide at 20℃; for 12h;79%
4-(3-(3-fluoro-4-hydroxyphenyl)-4,4-dimethyl-5-oxo-2-thioxoimidazolidin-1-yl)-2-(trifluoromethyl)benzonitrile

4-(3-(3-fluoro-4-hydroxyphenyl)-4,4-dimethyl-5-oxo-2-thioxoimidazolidin-1-yl)-2-(trifluoromethyl)benzonitrile

(R)-tetrahydrofuran-3-yl 4-methylbenzenesulfonate
219823-47-9

(R)-tetrahydrofuran-3-yl 4-methylbenzenesulfonate

(S)-4-(3-(3-fluoro-4-((tetrahydrofuran-3-yl)oxy)phenyl)-4,4-dimethyl-5-oxo-2-thioxoimidazolidin-1-yl)-2-(trifluoromethyl)benzonitrile

(S)-4-(3-(3-fluoro-4-((tetrahydrofuran-3-yl)oxy)phenyl)-4,4-dimethyl-5-oxo-2-thioxoimidazolidin-1-yl)-2-(trifluoromethyl)benzonitrile

Conditions
ConditionsYield
With caesium carbonate In N,N-dimethyl acetamide at 60℃; for 2h; Inert atmosphere;77.9%
With caesium carbonate In N,N-dimethyl acetamide; water at 60℃; for 2h;77.9%
tert-butyl (2R,4R)-4-amino-2-methylpiperidine-1-carboxylate

tert-butyl (2R,4R)-4-amino-2-methylpiperidine-1-carboxylate

(R)-tetrahydrofuran-3-yl 4-methylbenzenesulfonate
219823-47-9

(R)-tetrahydrofuran-3-yl 4-methylbenzenesulfonate

C15H28N2O3

C15H28N2O3

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In acetonitrile at 95℃; for 48h;76%
5-(4-fluoro-2-hydroxyphenyl)-9-{2-methyl-2-[3-(trifluoromethyl)phenyl]propanoyl}-1,3,9-triazaspiro[5.5]undecan-2-one

5-(4-fluoro-2-hydroxyphenyl)-9-{2-methyl-2-[3-(trifluoromethyl)phenyl]propanoyl}-1,3,9-triazaspiro[5.5]undecan-2-one

(R)-tetrahydrofuran-3-yl 4-methylbenzenesulfonate
219823-47-9

(R)-tetrahydrofuran-3-yl 4-methylbenzenesulfonate

5-(4-fluoro-2-{[(3S)-oxolan-3-yl]oxy}phenyl)-9-{2-methyl-2-[3-(trifluoromethyl)phenyl]propanoyl}-1,3,9-triazaspiro[5.5]undecan-2-one

5-(4-fluoro-2-{[(3S)-oxolan-3-yl]oxy}phenyl)-9-{2-methyl-2-[3-(trifluoromethyl)phenyl]propanoyl}-1,3,9-triazaspiro[5.5]undecan-2-one

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 100℃; for 5h;74%
4-hydroxy-benzaldehyde
123-08-0

4-hydroxy-benzaldehyde

(R)-tetrahydrofuran-3-yl 4-methylbenzenesulfonate
219823-47-9

(R)-tetrahydrofuran-3-yl 4-methylbenzenesulfonate

(S)-4-((tetrahydrofuran-3-yl)oxy)benzaldehyde

(S)-4-((tetrahydrofuran-3-yl)oxy)benzaldehyde

Conditions
ConditionsYield
With caesium carbonate In N,N-dimethyl-formamide at 100℃; for 14h;70%
methyl 3-hydroxy-5-(5-methyl-1,3-thiazol-2-yl)benzoate

methyl 3-hydroxy-5-(5-methyl-1,3-thiazol-2-yl)benzoate

(R)-tetrahydrofuran-3-yl 4-methylbenzenesulfonate
219823-47-9

(R)-tetrahydrofuran-3-yl 4-methylbenzenesulfonate

methyl 3-(5-methyl-1,3-thiazol-2-yl)-5-[(3S)-tetrahydrofuran-3-yloxy]benzoate

methyl 3-(5-methyl-1,3-thiazol-2-yl)-5-[(3S)-tetrahydrofuran-3-yloxy]benzoate

Conditions
ConditionsYield
With caesium carbonate In N,N-dimethyl-formamide at 90℃; for 36h;67%
3-bromo-5-hydroxy-benzoic acid methyl ester
192810-12-1

3-bromo-5-hydroxy-benzoic acid methyl ester

(R)-tetrahydrofuran-3-yl 4-methylbenzenesulfonate
219823-47-9

(R)-tetrahydrofuran-3-yl 4-methylbenzenesulfonate

methyl 3-bromo-5-[(3S)-tetrahydrofuran-3-yloxy]benzoate

methyl 3-bromo-5-[(3S)-tetrahydrofuran-3-yloxy]benzoate

Conditions
ConditionsYield
With caesium carbonate In N,N-dimethyl-formamide at 80℃;67%
6-(4-hydroxy-1,2-dihydrofuro[3,2-f]quinolin-9-yloxy)-N-methyl-1-naphthamide

6-(4-hydroxy-1,2-dihydrofuro[3,2-f]quinolin-9-yloxy)-N-methyl-1-naphthamide

(R)-tetrahydrofuran-3-yl 4-methylbenzenesulfonate
219823-47-9

(R)-tetrahydrofuran-3-yl 4-methylbenzenesulfonate

(S)-6-((4-((tetrahydrofuran-3-yl)oxy)-1,2-dihydrofuro[3,2-f] quinolin-9-yl)oxy)-Ν-methyl-1-naphthamide

(S)-6-((4-((tetrahydrofuran-3-yl)oxy)-1,2-dihydrofuro[3,2-f] quinolin-9-yl)oxy)-Ν-methyl-1-naphthamide

Conditions
ConditionsYield
With caesium carbonate In N,N-dimethyl acetamide at 60℃; for 0.5h; Inert atmosphere;67%
4-bromo-3-methoxyphenol
102127-34-4

4-bromo-3-methoxyphenol

(R)-tetrahydrofuran-3-yl 4-methylbenzenesulfonate
219823-47-9

(R)-tetrahydrofuran-3-yl 4-methylbenzenesulfonate

C11H13BrO3

C11H13BrO3

Conditions
ConditionsYield
With caesium carbonate In N,N-dimethyl-formamide at 80℃; for 16h;64%
GSK333081

GSK333081

(R)-tetrahydrofuran-3-yl 4-methylbenzenesulfonate
219823-47-9

(R)-tetrahydrofuran-3-yl 4-methylbenzenesulfonate

1-isopropyl-3-(β-D-glucopyranosyloxy)-4-[4-((S)-tetrahydrofuran-3-yloxy)benzyl]-5-methyl-1H-pyrazole

1-isopropyl-3-(β-D-glucopyranosyloxy)-4-[4-((S)-tetrahydrofuran-3-yloxy)benzyl]-5-methyl-1H-pyrazole

Conditions
ConditionsYield
With caesium carbonate In DMF (N,N-dimethyl-formamide) at 50℃; for 16h;60%
(2S,3R,4R,5S,6R)-2-(4-chloro-3-(4-hydroxybenzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol
864070-37-1

(2S,3R,4R,5S,6R)-2-(4-chloro-3-(4-hydroxybenzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol

(R)-tetrahydrofuran-3-yl 4-methylbenzenesulfonate
219823-47-9

(R)-tetrahydrofuran-3-yl 4-methylbenzenesulfonate

empagliflozin
864070-44-0

empagliflozin

Conditions
ConditionsYield
With caesium carbonate In N,N-dimethyl-formamide at 75℃; for 21h;57%
With caesium carbonate In N,N-dimethyl-formamide at 75℃; for 18h;49%
With caesium carbonate In N,N-dimethyl-formamide at 75℃; for 18h;49%
With caesium carbonate at 25 - 40℃;
With caesium carbonate In N,N-dimethyl-formamide at 30 - 45℃; for 24h;0.55 kg
4-bromo-2(1H)-pyridinone
36953-37-4

4-bromo-2(1H)-pyridinone

(R)-tetrahydrofuran-3-yl 4-methylbenzenesulfonate
219823-47-9

(R)-tetrahydrofuran-3-yl 4-methylbenzenesulfonate

A

4-bromo-1-[(S)-tetrahydro-furan-3-yl]-1H-pyridin-2-one
1237534-49-4

4-bromo-1-[(S)-tetrahydro-furan-3-yl]-1H-pyridin-2-one

B

4-bromo-2-[(S)-tetrahydro-furan-3-yloxy]-pyridine
1237534-50-7

4-bromo-2-[(S)-tetrahydro-furan-3-yloxy]-pyridine

Conditions
ConditionsYield
With potassium carbonate In dimethyl sulfoxide at 80℃;A 16%
B 56%
With potassium carbonate In dimethyl sulfoxide at 80℃;
4-(3-(6-hydroxypyridin-3-yl)-4,4-dimethyl-5-oxo-2-thioxoimidazolidin-1-yl)-2-(trifluoromethyl)benzonitrile

4-(3-(6-hydroxypyridin-3-yl)-4,4-dimethyl-5-oxo-2-thioxoimidazolidin-1-yl)-2-(trifluoromethyl)benzonitrile

(R)-tetrahydrofuran-3-yl 4-methylbenzenesulfonate
219823-47-9

(R)-tetrahydrofuran-3-yl 4-methylbenzenesulfonate

(S)-4-(4,4-dimethyl-5-oxo-3-(6-((tetrahydrofuran-3-yl)oxy)pyridin-3-yl)-2-thioxoimidazolidin-1-yl)-2-(trifluoromethyl)benzonitrile

(S)-4-(4,4-dimethyl-5-oxo-3-(6-((tetrahydrofuran-3-yl)oxy)pyridin-3-yl)-2-thioxoimidazolidin-1-yl)-2-(trifluoromethyl)benzonitrile

Conditions
ConditionsYield
With caesium carbonate In N,N-dimethyl acetamide at 60℃; for 2h; Inert atmosphere;52.6%
With caesium carbonate In N,N-dimethyl acetamide at 60℃; for 2h;52.6%
4-(4-(methoxymethyl)-2-((1s,4s)-4-methylcyclohexylamino)-6-(oxetan-3-yloxy)pyrimidin-5-yl)phenol

4-(4-(methoxymethyl)-2-((1s,4s)-4-methylcyclohexylamino)-6-(oxetan-3-yloxy)pyrimidin-5-yl)phenol

(R)-tetrahydrofuran-3-yl 4-methylbenzenesulfonate
219823-47-9

(R)-tetrahydrofuran-3-yl 4-methylbenzenesulfonate

4-(methoxymethyl)-N-((1s,4s)-4-methylcyclohexyl)-6-(oxetan-3-yloxy)-5-(4-((S)-tetrahydrofuran-3-yloxy)phenyl)pyrimidin-2-amine

4-(methoxymethyl)-N-((1s,4s)-4-methylcyclohexyl)-6-(oxetan-3-yloxy)-5-(4-((S)-tetrahydrofuran-3-yloxy)phenyl)pyrimidin-2-amine

Conditions
ConditionsYield
With caesium carbonate In N,N-dimethyl-formamide at 20℃;52%
5-(4-fluoro-2-hydroxyphenyl)-9-{[2-(trifluoromethoxy)phenyl]acetyl}-1,3,9-triazaspiro[5.5]undecan-2-one

5-(4-fluoro-2-hydroxyphenyl)-9-{[2-(trifluoromethoxy)phenyl]acetyl}-1,3,9-triazaspiro[5.5]undecan-2-one

(R)-tetrahydrofuran-3-yl 4-methylbenzenesulfonate
219823-47-9

(R)-tetrahydrofuran-3-yl 4-methylbenzenesulfonate

5-(4-fluoro-2-{[(3S)-oxolan-3-yl]oxy}phenyl)-9-{[2-(trifluoromethoxy)phenyl]acetyl}-1,3,9-triaza-spiro[5.5]undecan-2-one

5-(4-fluoro-2-{[(3S)-oxolan-3-yl]oxy}phenyl)-9-{[2-(trifluoromethoxy)phenyl]acetyl}-1,3,9-triaza-spiro[5.5]undecan-2-one

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 100℃; for 5h;52%
(2S,3R,4R,5S,6R)-2-(3-(4-hydroxybenzyl)-4-methylphenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol
333360-66-0

(2S,3R,4R,5S,6R)-2-(3-(4-hydroxybenzyl)-4-methylphenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol

(R)-tetrahydrofuran-3-yl 4-methylbenzenesulfonate
219823-47-9

(R)-tetrahydrofuran-3-yl 4-methylbenzenesulfonate

1-methyl-2-[4-((S)-tetrahydrofuran-3-yloxy)-benzyl]-4-(β-D-glucopyranos-1-yl)-benzene
892486-47-4

1-methyl-2-[4-((S)-tetrahydrofuran-3-yloxy)-benzyl]-4-(β-D-glucopyranos-1-yl)-benzene

Conditions
ConditionsYield
With caesium carbonate In N,N-dimethyl-formamide at 60 - 80℃; for 22h;46%
6-(3-azabicyclo[3.1.0]hexan-6-yl)-5-methyl-1-(tetrahydro-2H-pyran-2-yl)-1H-indazole

6-(3-azabicyclo[3.1.0]hexan-6-yl)-5-methyl-1-(tetrahydro-2H-pyran-2-yl)-1H-indazole

(R)-tetrahydrofuran-3-yl 4-methylbenzenesulfonate
219823-47-9

(R)-tetrahydrofuran-3-yl 4-methylbenzenesulfonate

5-methyl-1-(tetrahydro-2H-pyran-2-yl)-6-(3-((S)-tetrahydrofuran-3-yl)-3-azabicyclo[3.1.0]hexan-6-yl)-1H-indazole

5-methyl-1-(tetrahydro-2H-pyran-2-yl)-6-(3-((S)-tetrahydrofuran-3-yl)-3-azabicyclo[3.1.0]hexan-6-yl)-1H-indazole

Conditions
ConditionsYield
With potassium carbonate at 110℃; for 16h;40%
(R)-tetrahydrofuran-3-yl 4-methylbenzenesulfonate
219823-47-9

(R)-tetrahydrofuran-3-yl 4-methylbenzenesulfonate

4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol
269409-70-3

4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol

2-(4-((S)-tetrahydrofuran-3-yloxy)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
1416157-64-6

2-(4-((S)-tetrahydrofuran-3-yloxy)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 85℃; for 15h;30%
4-(4-methyl-2-((1s,4s)-4-methylcyclohexylamino)-6-(oxetan-3-yloxy)pyrimidin-5-yl)phenol

4-(4-methyl-2-((1s,4s)-4-methylcyclohexylamino)-6-(oxetan-3-yloxy)pyrimidin-5-yl)phenol

(R)-tetrahydrofuran-3-yl 4-methylbenzenesulfonate
219823-47-9

(R)-tetrahydrofuran-3-yl 4-methylbenzenesulfonate

4-methyl-N-((1S,4S)-4-methylcyclohexyl)-6-(oxetan-3-yloxy)-5-(4-((S)-tetrahydrofuran-3-yloxy)phenyl)pyrimidin-2-amine

4-methyl-N-((1S,4S)-4-methylcyclohexyl)-6-(oxetan-3-yloxy)-5-(4-((S)-tetrahydrofuran-3-yloxy)phenyl)pyrimidin-2-amine

Conditions
ConditionsYield
With caesium carbonate; potassium iodide In N,N-dimethyl-formamide at 20 - 90℃; for 4.5h;30%
(6aS,8S)-4-iodo-6a,7,8,9-tetrahydro-6H-pyrido[3,2-b]pyrrolo[1,2-d][1,4]oxazin-8-ol

(6aS,8S)-4-iodo-6a,7,8,9-tetrahydro-6H-pyrido[3,2-b]pyrrolo[1,2-d][1,4]oxazin-8-ol

(R)-tetrahydrofuran-3-yl 4-methylbenzenesulfonate
219823-47-9

(R)-tetrahydrofuran-3-yl 4-methylbenzenesulfonate

(6aS,8S)-4-iodo-8-(((S)-tetrahydrofuran-3-yl)oxy)-6a,7,8,9-tetrahydro-6H-pyrido[3,2-b]pyrrolo[1,2-d][1,4]oxazine

(6aS,8S)-4-iodo-8-(((S)-tetrahydrofuran-3-yl)oxy)-6a,7,8,9-tetrahydro-6H-pyrido[3,2-b]pyrrolo[1,2-d][1,4]oxazine

Conditions
ConditionsYield
With sodium hydride In N,N-dimethyl-formamide; mineral oil at 0 - 20℃; Inert atmosphere;28.68%
4-carbethoxypiperidine
1126-09-6

4-carbethoxypiperidine

(R)-tetrahydrofuran-3-yl 4-methylbenzenesulfonate
219823-47-9

(R)-tetrahydrofuran-3-yl 4-methylbenzenesulfonate

ethyl 1-[(3S)-tetrahydrofuran-3-yl]piperidine-4-carboxylate

ethyl 1-[(3S)-tetrahydrofuran-3-yl]piperidine-4-carboxylate

Conditions
ConditionsYield
With potassium carbonate In acetonitrile at 70℃; for 24h;27%
(1R,4R)-5-(6-(6-(3-azabicyclo[3.1.0] hexan-6-yl)-5-methyl-1H-indazol-1-yl)-2-methylpyrimidin-4-yl)-2-oxa-5-azabicyclo[2.2.1]heptane

(1R,4R)-5-(6-(6-(3-azabicyclo[3.1.0] hexan-6-yl)-5-methyl-1H-indazol-1-yl)-2-methylpyrimidin-4-yl)-2-oxa-5-azabicyclo[2.2.1]heptane

(R)-tetrahydrofuran-3-yl 4-methylbenzenesulfonate
219823-47-9

(R)-tetrahydrofuran-3-yl 4-methylbenzenesulfonate

(1R,4R)-5-(2-methyl-6-(5-methyl-6-(3-((S)-tetrahydrofuran-3-yl)-3-azabicyclo[3.1.0] hexan-6-yl)-1H-indazol-1-yl)pyrimidin-4-yl)-2-oxa-5-azabicyclo[2.2.1]heptane

(1R,4R)-5-(2-methyl-6-(5-methyl-6-(3-((S)-tetrahydrofuran-3-yl)-3-azabicyclo[3.1.0] hexan-6-yl)-1H-indazol-1-yl)pyrimidin-4-yl)-2-oxa-5-azabicyclo[2.2.1]heptane

Conditions
ConditionsYield
With potassium carbonate In acetonitrile at 110℃; for 24h; Inert atmosphere;19%
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