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Afine Chemicals Limited

Our Services 1. New Molecules R&D 2. Own test center HPLC NMR GC LC-MS 3. API and Intermediates from China reputed manufacturers 4. Documents support COA MOA MSDS DMF open part Our advantages 1. Government awarded company. Top 100 enter

afine-Sevoflurane

Cas:28523-86-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Dingyan Chem Co., Ltd

Items Standard Result Appearance Clear, colorless, mobile and heavy liquid Conforms Assay

Top purity Sevoflurane with high quality and best price cas:28523-86-6

Cas:28523-86-6

Min.Order:1 Kilogram

FOB Price: $3.0 / 10.0

Type:Manufacturers

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Hangzhou JINLAN Pharm-Drugs Technology Co., Ltd

We can provide GMP validation service that complies with SFDA, FDA, WHO and EU EMPA.Excellent registration team could help us easlily to register our products in different countries.If you and your customer are interested in some products or need C

Sevoflurane for inhalation 100%*250ml

Cas:28523-86-6

Min.Order:1 Gram

Negotiable

Type:Manufacturers

inquiry

Hebei yanxi chemical co.,LTD.

hebei yanxi chemical co., LTD who registered capital of 10 million yuan, nearly to $2 million, we have a pharmaceutical raw materials factory production of pharmaceutical raw materials, and a reagent r&d center, and we do research and developm

Sevoflurane Manufacturer/High quality 28523-86-6

Cas:28523-86-6

Min.Order:1 Metric Ton

FOB Price: $1.0 / 3.0

Type:Manufacturers

inquiry

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

1,1,1,3,3,3-Hexafluoro-2-(fluoromethoxy)-propane

Cas:28523-86-6

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Henan Tianfu Chemical Co., Ltd.

Sevoflurane Basic information Product Name: Sevoflurane Synonyms: SEVOFLURANE;1,1,1,3,3,3-hexafluoro-2-(fluoromethoxy)-propan;flu

TIANFU-CHEM Sevoflurane 28523-86-6

Cas:28523-86-6

Min.Order:1 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

Our advantages: 1, High quality with competitive price: 1) Standard:BP/USP/EP/Enterprise standard 2) All Purity≥99% 3) We are manufacturer and can provide high quality products with factory price. 2, Fast and safe delivery 1) Parcel can be sent

Sevoflurane

Cas:28523-86-6

Min.Order:1 Kilogram

FOB Price: $9.0 / 99.0

Type:Trading Company

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

New production CAS 28523-86-6 with best quality

Cas:28523-86-6

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

Sevoflurane Manufacturer/High quality 28523-86-6

Cas:28523-86-6

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

inquiry

Antimex Chemical Limied

28523-86-6 cheap price 98%MIN factory CAS: 28523-86-6 Sevoflurane mr6s4;Ultane;R-E 347;Sevoness;347mmzEbg;Sevofrane;SEVOFLURANE;Sevoflurane (1 mL);1H,1H,3H-Perfluoro(3-methyl-2-oxabutane);Fluoromethyl 2H-

28523-86-6 cheap price 98%MIN factory

Cas:28523-86-6

Min.Order:500 Kilogram

FOB Price: $20.0

Type:Lab/Research institutions

inquiry

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

Propane,1,1,1,3,3,3-hexafluoro-2-(fluoromethoxy)- 28523-86-6

Cas:28523-86-6

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Qingdao Beluga Import and Export Co., LTD

Sevoflurane CAS:28523-86-6 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic intermediates

Sevoflurane CAS:28523-86-6

Cas:28523-86-6

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

Propane,1,1,1,3,3,3-hexafluoro-2-(fluoromethoxy)-

Cas:28523-86-6

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

Propane,1,1,1,3,3,3-hexafluoro-2-(fluoromethoxy)-

Cas:28523-86-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

Sevoflurane

Cas:28523-86-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply Sevoflurane

Cas:28523-86-6

Min.Order:0 Metric Ton

Negotiable

Type:Other

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

High quality Sevoflurane

Cas:28523-86-6

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

Hangzhou Lingrui Chemical Co.,Ltd.

28523-86-6 cheap price 98%MIN factoryAppearance:Colorles liquid Storage:dry Package:according to customers' requirements Application:CAS 28523-86-6 Transportation:By air(EMS or EUB or FedEx or TNT ect...) or by sea(FOB or CIF or CNF ect...)or accor

28523-86-6 cheap price 98%MIN factory

Cas:28523-86-6

Min.Order:1 Gram

Negotiable

Type:Other

inquiry

HANGZHOU YUNUO CHEMICAL CO.,LTD

Superior quality, moderate price & quick delivery. Appearance:colourless liquid Storage:Stored in cool, dry and ventilation place; Away from fire and heat Package:25kg/drum, or as per your request. Application:Used as Pharmaceutical Intermediat

Propane,1,1,1,3,3,3-hexafluoro-2-(fluoromethoxy)-

Cas:28523-86-6

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

TaiChem Taizhou Limited

Established in May 2015, TaiChem Ltd. is initially invested by a British research and development company and started by PhDs back from aboard. The company is registered in China Medical City (CMC), Taizhou, Jiangsu Province, and the production site

Sevoflurane

Cas:28523-86-6

Min.Order:10 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Zibo Dorne chemical technology co. LTD

Product Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,

Sevoflurane

Cas:28523-86-6

Min.Order:1 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Jiangsu Qianyu Molecular Technology Co., LTD.

Our Advantages A. International Top level TechnologyOur company owned biomedicine experts are famous at home and abroad with rich experience in research and development in the field of efficient chiral functional molecules research and development an

Factory SupplierSevoflurane

Cas:28523-86-6

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Xiamen Jenny Chemical Technology Co., Ltd.

GMP standard, high purity, competitive price, in stock 1. Quick Response: within 6 hours after receiving your email. 2. Quality Guarantee: All products are strictly tested by our QC, confirmed by QA, and approved by a third-party lab in China, USA,

sevoflurane

Cas:28523-86-6

Min.Order:1 Milligram

Negotiable

Type:Trading Company

inquiry

Shanghai Minstar Chemical Co., Ltd

Sevoflurane Basic information Product Name: Sevoflurane Synonyms: mr6s4;FLUOROMETHYL 1,1,1,3,3,3-HEXAFLUOROISOPROPYL ETHER;Fluoromethyl 1-(trifluoromethyl)-2,2,2-trifluoroethyl ether;Sevoness;347mmzEbg;Ether, fluoromethyl 2,2,2-trifluoro-1-(tr

Sevoflurane

Cas:28523-86-6

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

EAST CHEMSOURCES LIMITED

factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B

Sevoflurane Manufacturer/High quality 28523-86-6

Cas:28523-86-6

Min.Order:1 Kilogram

FOB Price: $18.0 / 20.0

Type:Trading Company

inquiry

Siwei Development Group Ltd.

Product name: Sevoflurane CAS No.: 28523-86-6 Molecule Formula:C4H3F7O Molecule Weight:200.05 Purity: 98.5% Package: 25kg/drum Description: White crystalline powder Manufacture Standards:USP Testing Items

High Quality Sevoflurane

Cas:28523-86-6

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

TAIZHOU ZHENYU BIOTECHNOLOGY CO., LTD

Zhenyu biotech exported this product to many countries and regions at best price. if you are looking for the material's manufacturer or supplier in china, zhenyu biotech is your best choice. pls contact with us freely for getting detailed

Sevoflurane

Cas:28523-86-6

Min.Order:1 Kilogram

FOB Price: $2.0

Type:Lab/Research institutions

inquiry

Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

Sevoflurane

Cas:28523-86-6

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

Sevoflurane Manufacturer/High quality 28523-86-6

Cas:28523-86-6

Min.Order:1 Metric Ton

FOB Price: $1.5

Type:Trading Company

inquiry

Hangzhou Zhongqi chem Co.,Ltd.

Located in Hangzhou National Hi-Tech Industrial Development Zone, zhongqichem is a technical company mainly focus on the Custom synthesis, manufacturing, sales of chemicals to various industries. Benefiting from the outstanding customer service and h

Propane,1,1,1,3,3,3-hexafluoro-2-(fluoromethoxy)-

Cas:28523-86-6

Min.Order:0

Negotiable

Type:Other

inquiry

Synthetic route

1,1,1,3,3,3-hexafluoroisopropyl chloromethyl ether
26103-07-1

1,1,1,3,3,3-hexafluoroisopropyl chloromethyl ether

sevoflurane
28523-86-6

sevoflurane

Conditions
ConditionsYield
With diisopropylethylamine hydrofluoride for 16h; Heating;95%
With potassium fluoride; potassium hydrogenfluoride; water; Aliquat HTA-1 at 100℃; for 3h; Product distribution / selectivity;90%
With potassium fluoride; tetraethylammonium chloride In water at 100℃; for 3h; Product distribution / selectivity;86%
1,1,1,3,3,3-hexafluoroisopropyl chloromethyl ether
26103-07-1

1,1,1,3,3,3-hexafluoroisopropyl chloromethyl ether

A

1,1,1,3',3',3'-hexafluoro-propanol
920-66-1

1,1,1,3',3',3'-hexafluoro-propanol

B

sevoflurane
28523-86-6

sevoflurane

Conditions
ConditionsYield
With hydrogenchloride; potassium fluoride; water; Aliquat HTA-1 at 100℃; for 3h; Product distribution / selectivity;A 1.05 %Chromat.
B 93%
With potassium fluoride; potassium hydrogenfluoride; water; Aliquat 175 at 100℃; for 3h; Product distribution / selectivity;A 3.8 %Chromat.
B 89%
With potassium fluoride; potassium hydrogenfluoride; water; benzyl triethyl ammonium dichloride at 100℃; for 3h; Product distribution / selectivity;A 4 %Chromat.
B 88%
fluoroiodomethane
373-53-5

fluoroiodomethane

1,1,1,3',3',3'-hexafluoro-propanol
920-66-1

1,1,1,3',3',3'-hexafluoro-propanol

sevoflurane
28523-86-6

sevoflurane

Conditions
ConditionsYield
With triethylamine In acetonitrile at 60℃; for 8h; Product distribution / selectivity; Inert atmosphere; Sealed vesselaturated gas;91.43%
With triethylamine; potassium hydroxide In acetonitrile at 60℃; for 8h; Product distribution / selectivity; Inert atmosphere;91.43%
1,3,5-Trioxan
110-88-3

1,3,5-Trioxan

1,1,1,3',3',3'-hexafluoro-propanol
920-66-1

1,1,1,3',3',3'-hexafluoro-propanol

sevoflurane
28523-86-6

sevoflurane

Conditions
ConditionsYield
boron trifluoride diethyl etherate for 5h; Product distribution / selectivity; Heating / reflux;84%
aluminum(III) fluoride In chloroform for 5h; Product distribution / selectivity; Heating / reflux;72%
With hydrogen fluoride at -30 - 67℃; under 2257.73 - 3862.89 Torr; Pressure; Temperature;
S-monofluoromethyl-S-phenyl-2,3,4,5-tetramethylphenylsulphonium tetrafluoroborate

S-monofluoromethyl-S-phenyl-2,3,4,5-tetramethylphenylsulphonium tetrafluoroborate

1,1,1,3',3',3'-hexafluoro-propanol
920-66-1

1,1,1,3',3',3'-hexafluoro-propanol

sevoflurane
28523-86-6

sevoflurane

Conditions
ConditionsYield
With caesium carbonate In acetonitrile at 20℃;83%
bromofluoromethane
373-52-4

bromofluoromethane

1,1,1,3',3',3'-hexafluoro-propanol
920-66-1

1,1,1,3',3',3'-hexafluoro-propanol

sevoflurane
28523-86-6

sevoflurane

Conditions
ConditionsYield
With triethylamine In acetonitrile at 60℃; for 8h; Product distribution / selectivity; Inert atmosphere; Sealed vessel;81.8%
With triethylamine; potassium hydroxide In acetonitrile at 60℃; for 8h; Product distribution / selectivity; Inert atmosphere;81.8%
1,1,1,3',3',3'-hexafluoro-propanol
920-66-1

1,1,1,3',3',3'-hexafluoro-propanol

sevoflurane
28523-86-6

sevoflurane

Conditions
ConditionsYield
With sodium carbonate In 1-methyl-pyrrolidin-2-one; water at 50℃; for 6h; Product distribution / selectivity; Sealed vessel;71.57%
With 1-methyl-pyrrolidin-2-one; sodium carbonate In water at 50℃; for 6h;71.57%
1,3,5-tri-O-benzoyl-2-deoxy-2-fluoro-α-D-arabinofuranose
97614-43-2

1,3,5-tri-O-benzoyl-2-deoxy-2-fluoro-α-D-arabinofuranose

sevoflurane
28523-86-6

sevoflurane

Conditions
ConditionsYield
With potassium fluoride In various solvent(s) at 95℃; for 1h; Substitution;71%
bis {[2,2,2-trifluoro-1-(trifluoromethyl)ethoxy]methyl} ether
194039-83-3

bis {[2,2,2-trifluoro-1-(trifluoromethyl)ethoxy]methyl} ether

sevoflurane
28523-86-6

sevoflurane

Conditions
ConditionsYield
With hydrogen fluoride at -30 - 70℃; for 1.5h;53%
methyl 3,3,3-trifluoro-2-trifluoromethyl-2-chloromethoxypropionate
1152045-94-7

methyl 3,3,3-trifluoro-2-trifluoromethyl-2-chloromethoxypropionate

sevoflurane
28523-86-6

sevoflurane

Conditions
ConditionsYield
With potassium fluoride In polyethyleneglycol at 90 - 95℃; for 5h; Product distribution / selectivity; Autoclave;51.7%
1,3,5-Trioxan
110-88-3

1,3,5-Trioxan

1,1,1,3',3',3'-hexafluoro-propanol
920-66-1

1,1,1,3',3',3'-hexafluoro-propanol

A

formaldehyde methyl [2,2,2-trifluoro-1-(trifluoromethyl)ethyl] acetal
194039-87-7

formaldehyde methyl [2,2,2-trifluoro-1-(trifluoromethyl)ethyl] acetal

B

formaldehyde fluoromethyl [2,2,2-trifluoro-1-(trifluoromethyl)ethyl] acetal
194039-91-3

formaldehyde fluoromethyl [2,2,2-trifluoro-1-(trifluoromethyl)ethyl] acetal

C

bis {[2,2,2-trifluoro-1-(trifluoromethyl)ethoxy]methyl} ether
194039-83-3

bis {[2,2,2-trifluoro-1-(trifluoromethyl)ethoxy]methyl} ether

D

sevoflurane
28523-86-6

sevoflurane

E

formaldehyde di[2,2,2-trifluoro-1-(trifluoromethyl)ethyl] acetal

formaldehyde di[2,2,2-trifluoro-1-(trifluoromethyl)ethyl] acetal

Conditions
ConditionsYield
With hydrogen fluoride at 31 - 65℃; under 1275.13 - 2467.75 Torr; for 6h; Inert atmosphere;A n/a
B n/a
C n/a
D 23%
E n/a
1,3,5-Trioxan
110-88-3

1,3,5-Trioxan

1,1,1,3',3',3'-hexafluoro-propanol
920-66-1

1,1,1,3',3',3'-hexafluoro-propanol

A

formaldehyde fluoromethyl [2,2,2-trifluoro-1-(trifluoromethyl)ethyl] acetal
194039-91-3

formaldehyde fluoromethyl [2,2,2-trifluoro-1-(trifluoromethyl)ethyl] acetal

B

bis {[2,2,2-trifluoro-1-(trifluoromethyl)ethoxy]methyl} ether
194039-83-3

bis {[2,2,2-trifluoro-1-(trifluoromethyl)ethoxy]methyl} ether

C

sevoflurane
28523-86-6

sevoflurane

D

formaldehyde di[2,2,2-trifluoro-1-(trifluoromethyl)ethyl] acetal

formaldehyde di[2,2,2-trifluoro-1-(trifluoromethyl)ethyl] acetal

Conditions
ConditionsYield
With hydrogen fluoride at 56 - 65℃; under 1275.13 - 2467.75 Torr; for 6h; Inert atmosphere;A n/a
B n/a
C 23%
D n/a
bis(2-chloromethyl)ether
542-88-1

bis(2-chloromethyl)ether

sevoflurane
28523-86-6

sevoflurane

Conditions
ConditionsYield
With BrF3
Na2 SO3

Na2 SO3

(CF3)2 CHOCH2 F

(CF3)2 CHOCH2 F

(ClF2 C)(F3 C)CHOCH2 F

(ClF2 C)(F3 C)CHOCH2 F

(ClF2 C)2 CHOCH2 F

(ClF2 C)2 CHOCH2 F

1,1,1,3,3,3-hexachloro-2-methoxy-propane
98020-32-7

1,1,1,3,3,3-hexachloro-2-methoxy-propane

sevoflurane
28523-86-6

sevoflurane

Conditions
ConditionsYield
With sodium hydroxide In BrF3
methyl 3,3,3-trifluoro-2-hydroxy-2-(trifluoromethyl)propionate
7594-51-6

methyl 3,3,3-trifluoro-2-hydroxy-2-(trifluoromethyl)propionate

C6H5F7O3
1000699-24-0

C6H5F7O3

Methyl 3,3,3-trifluoro-2-trifluoromethyl-2-methoxypropionate
13859-30-8

Methyl 3,3,3-trifluoro-2-trifluoromethyl-2-methoxypropionate

A

potassium 3,3,3-trifluoro-2-trifluoromethyl-2-hydroxypropionate
118217-64-4

potassium 3,3,3-trifluoro-2-trifluoromethyl-2-hydroxypropionate

B

MTTMP; potassium salt
960005-34-9

MTTMP; potassium salt

C

sevoflurane
28523-86-6

sevoflurane

D

1,1,1,3,3,3-hexafluoro-2-methoxypropane
13171-18-1

1,1,1,3,3,3-hexafluoro-2-methoxypropane

Conditions
ConditionsYield
With potassium hydroxide; water at 50℃; for 2h;A 99 %Spectr.
B 71 %Spectr.
C 89 %Spectr.
D 5 %Spectr.
With water; potassium carbonate at 50℃;
diethyl-2-(chloromethoxy)malonate
1265520-63-5

diethyl-2-(chloromethoxy)malonate

sevoflurane
28523-86-6

sevoflurane

Conditions
ConditionsYield
With sulfur tetrafluoride; hydrogen fluoride In Solkane365 mfc at 23 - 100℃; under 45004.5 Torr; Product distribution / selectivity;
1,1,1,3,3,3-hexafluoro-2-bromomethoxy-propane
28523-90-2

1,1,1,3,3,3-hexafluoro-2-bromomethoxy-propane

sevoflurane
28523-86-6

sevoflurane

Conditions
ConditionsYield
With potassium fluoride In sulfolane; 2,2'-[1,2-ethanediylbis(oxy)]bisethanol at 85℃; for 6h;
With potassium fluoride In sulfolane; 2,2'-[1,2-ethanediylbis(oxy)]bisethanol at 85℃; for 6h; Product distribution / selectivity;
iodomethyl 2,2,2-trifluoro-1-(trifluoromethyl)ethyl ether
1093627-71-4

iodomethyl 2,2,2-trifluoro-1-(trifluoromethyl)ethyl ether

sevoflurane
28523-86-6

sevoflurane

Conditions
ConditionsYield
With potassium fluoride In N,N-dimethyl-formamide; 2,2'-[1,2-ethanediylbis(oxy)]bisethanol at 85℃; for 6h;
With potassium fluoride In N,N-dimethyl-formamide; 2,2'-[1,2-ethanediylbis(oxy)]bisethanol at 85℃; for 6h; Product distribution / selectivity;
1,1,1,3',3',3'-hexafluoro-propanol
920-66-1

1,1,1,3',3',3'-hexafluoro-propanol

bis(fluoromethyl)-ether
462-51-1

bis(fluoromethyl)-ether

sevoflurane
28523-86-6

sevoflurane

Conditions
ConditionsYield
trifluorormethanesulfonic acid In dichloromethane at 25℃; for 15h; Product distribution / selectivity; Polyethylene container;58 %Chromat.
at 20℃; for 1h;
1,1,1,3,3-pentafluorobutane
406-58-6

1,1,1,3,3-pentafluorobutane

diethyl-2-(chloromethoxy)malonate
1265520-63-5

diethyl-2-(chloromethoxy)malonate

sevoflurane
28523-86-6

sevoflurane

Conditions
ConditionsYield
With sulfur tetrafluoride; hydrogen fluoride at 23 - 100℃; under 45004.5 Torr; Autoclave;
C4H5FO5
1393107-41-9

C4H5FO5

sevoflurane
28523-86-6

sevoflurane

Conditions
ConditionsYield
With sulfur tetrafluoride
formaldehyd
50-00-0

formaldehyd

1,1,1,3',3',3'-hexafluoro-propanol
920-66-1

1,1,1,3',3',3'-hexafluoro-propanol

sevoflurane
28523-86-6

sevoflurane

Conditions
ConditionsYield
Stage #1: formaldehyd; 1,1,1,3',3',3'-hexafluoro-propanol With hydrogen fluoride In dichloromethane Cooling with ice;
Stage #2: With sulfuric acid at 20℃; for 1h;
sevoflurane
28523-86-6

sevoflurane

1,1,1,3,3,3-hexafluoroisopropyl chloromethyl ether
26103-07-1

1,1,1,3,3,3-hexafluoroisopropyl chloromethyl ether

Conditions
ConditionsYield
In water79%
sevoflurane
28523-86-6

sevoflurane

fluoromethyl 2,2-difluoro-1-(trifluoromethyl)vinyl ether
58109-34-5

fluoromethyl 2,2-difluoro-1-(trifluoromethyl)vinyl ether

Conditions
ConditionsYield
With methyllithium In formaldehyde diethyl acetal at -31 - -20℃; Product distribution / selectivity; Inert atmosphere;50%
With lithium hexamethyldisilazane In tetrahydrofuran at -70℃; for 0.25h; Yield given;
sevoflurane
28523-86-6

sevoflurane

sodium methylate
124-41-4

sodium methylate

Fluoromethyl 2-methoxy-2,2-difluoro-1-(trifluoromethyl)ethyl ether
58109-33-4

Fluoromethyl 2-methoxy-2,2-difluoro-1-(trifluoromethyl)ethyl ether

Conditions
ConditionsYield
In methanol 1.) 15-22 deg C, 45 min; 2.) RT 1 3/4 h; 3.) reflux, 2 h;4.9 g
sevoflurane
28523-86-6

sevoflurane

sodium methylate
124-41-4

sodium methylate

A

Fluoromethyl 2-methoxy-2,2-difluoro-1-(trifluoromethyl)ethyl ether
58109-33-4

Fluoromethyl 2-methoxy-2,2-difluoro-1-(trifluoromethyl)ethyl ether

B

fluoromethyl 1-methoxy-1,3,3,3-tetrafluoro-2-propenyl ether

fluoromethyl 1-methoxy-1,3,3,3-tetrafluoro-2-propenyl ether

Conditions
ConditionsYield
at 35 - 40℃; for 0.5h; Yields of byproduct given;A n/a
B 0.375 g
sevoflurane
28523-86-6

sevoflurane

fluoromethyl 1-cyano-2,2,2-trifluoroethyl ether

fluoromethyl 1-cyano-2,2,2-trifluoroethyl ether

Conditions
ConditionsYield
With potassium carbonate; lithium hexamethyldisilazane In tetrahydrofuran at -65 - 0℃; for 0.5h; Yield given;
sevoflurane
28523-86-6

sevoflurane

A

Fluoromethyl 2-methoxy-2,2-difluoro-1-(trifluoromethyl)ethyl ether
58109-33-4

Fluoromethyl 2-methoxy-2,2-difluoro-1-(trifluoromethyl)ethyl ether

B

fluoromethyl 2,2-difluoro-1-(trifluoromethyl)vinyl ether
58109-34-5

fluoromethyl 2,2-difluoro-1-(trifluoromethyl)vinyl ether

C

(Z)-1,3,3,3-Tetrafluoro-2-fluoromethoxy-1-methoxy-propene

(Z)-1,3,3,3-Tetrafluoro-2-fluoromethoxy-1-methoxy-propene

D

1,1,3,3-Tetrafluoro-2-fluoromethoxy-3-methoxy-propene

1,1,3,3-Tetrafluoro-2-fluoromethoxy-3-methoxy-propene

Conditions
ConditionsYield
With soda lime at 120℃; for 0.666667h; Product distribution; Mechanism; further time and temperature; also with D2-sevoflurane;
sevoflurane
28523-86-6

sevoflurane

diisopropylethylamine hydrofluoride

diisopropylethylamine hydrofluoride

Conditions
ConditionsYield
With hydrogenchloride; hydrogen fluoride; N-ethyl-N,N-diisopropylamine In 1,1,1,3,3,3-hexafluoroisopropyl chloromethyl ether; water
1,1,1,3',3',3'-hexafluoro-propanol
920-66-1

1,1,1,3',3',3'-hexafluoro-propanol

sevoflurane
28523-86-6

sevoflurane

formaldehyde di[2,2,2-trifluoro-1-(trifluoromethyl)ethyl] acetal

formaldehyde di[2,2,2-trifluoro-1-(trifluoromethyl)ethyl] acetal

sevoflurane
28523-86-6

sevoflurane

C4H4F6O2

C4H4F6O2

Conditions
ConditionsYield
With aluminum oxide; Trimethylsilanol
C5H6F6O3

C5H6F6O3

sevoflurane
28523-86-6

sevoflurane

A

C6H7F7O3
194039-95-7

C6H7F7O3

B

dihexafluoro isopropanol triformal
1016982-73-2

dihexafluoro isopropanol triformal

C4H4F6O2

C4H4F6O2

sevoflurane
28523-86-6

sevoflurane

A

formaldehyde fluoromethyl [2,2,2-trifluoro-1-(trifluoromethyl)ethyl] acetal
194039-91-3

formaldehyde fluoromethyl [2,2,2-trifluoro-1-(trifluoromethyl)ethyl] acetal

B

1,1,1,3',3',3'-hexafluoro-propanol
920-66-1

1,1,1,3',3',3'-hexafluoro-propanol

C4H4F6O2

C4H4F6O2

sevoflurane
28523-86-6

sevoflurane

bis {[2,2,2-trifluoro-1-(trifluoromethyl)ethoxy]methyl} ether
194039-83-3

bis {[2,2,2-trifluoro-1-(trifluoromethyl)ethoxy]methyl} ether

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