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Cas:28523-86-6
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inquirySevoflurane Basic information Product Name: Sevoflurane Synonyms: SEVOFLURANE;1,1,1,3,3,3-hexafluoro-2-(fluoromethoxy)-propan;flu
Cas:28523-86-6
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Cas:28523-86-6
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Sevoflurane Basic information Product Name: Sevoflurane Synonyms: mr6s4;FLUOROMETHYL 1,1,1,3,3,3-HEXAFLUOROISOPROPYL ETHER;Fluoromethyl 1-(trifluoromethyl)-2,2,2-trifluoroethyl ether;Sevoness;347mmzEbg;Ether, fluoromethyl 2,2,2-trifluoro-1-(tr
factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B
Cas:28523-86-6
Min.Order:1 Kilogram
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inquiryProduct name: Sevoflurane CAS No.: 28523-86-6 Molecule Formula:C4H3F7O Molecule Weight:200.05 Purity: 98.5% Package: 25kg/drum Description: White crystalline powder Manufacture Standards:USP Testing Items
Cas:28523-86-6
Min.Order:1 Kilogram
Negotiable
Type:Trading Company
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inquiry1,1,1,3,3,3-hexafluoroisopropyl chloromethyl ether
sevoflurane
Conditions | Yield |
---|---|
With diisopropylethylamine hydrofluoride for 16h; Heating; | 95% |
With potassium fluoride; potassium hydrogenfluoride; water; Aliquat HTA-1 at 100℃; for 3h; Product distribution / selectivity; | 90% |
With potassium fluoride; tetraethylammonium chloride In water at 100℃; for 3h; Product distribution / selectivity; | 86% |
1,1,1,3,3,3-hexafluoroisopropyl chloromethyl ether
A
1,1,1,3',3',3'-hexafluoro-propanol
B
sevoflurane
Conditions | Yield |
---|---|
With hydrogenchloride; potassium fluoride; water; Aliquat HTA-1 at 100℃; for 3h; Product distribution / selectivity; | A 1.05 %Chromat. B 93% |
With potassium fluoride; potassium hydrogenfluoride; water; Aliquat 175 at 100℃; for 3h; Product distribution / selectivity; | A 3.8 %Chromat. B 89% |
With potassium fluoride; potassium hydrogenfluoride; water; benzyl triethyl ammonium dichloride at 100℃; for 3h; Product distribution / selectivity; | A 4 %Chromat. B 88% |
Conditions | Yield |
---|---|
With triethylamine In acetonitrile at 60℃; for 8h; Product distribution / selectivity; Inert atmosphere; Sealed vesselaturated gas; | 91.43% |
With triethylamine; potassium hydroxide In acetonitrile at 60℃; for 8h; Product distribution / selectivity; Inert atmosphere; | 91.43% |
Conditions | Yield |
---|---|
boron trifluoride diethyl etherate for 5h; Product distribution / selectivity; Heating / reflux; | 84% |
aluminum(III) fluoride In chloroform for 5h; Product distribution / selectivity; Heating / reflux; | 72% |
With hydrogen fluoride at -30 - 67℃; under 2257.73 - 3862.89 Torr; Pressure; Temperature; |
1,1,1,3',3',3'-hexafluoro-propanol
sevoflurane
Conditions | Yield |
---|---|
With caesium carbonate In acetonitrile at 20℃; | 83% |
Conditions | Yield |
---|---|
With triethylamine In acetonitrile at 60℃; for 8h; Product distribution / selectivity; Inert atmosphere; Sealed vessel; | 81.8% |
With triethylamine; potassium hydroxide In acetonitrile at 60℃; for 8h; Product distribution / selectivity; Inert atmosphere; | 81.8% |
Conditions | Yield |
---|---|
With sodium carbonate In 1-methyl-pyrrolidin-2-one; water at 50℃; for 6h; Product distribution / selectivity; Sealed vessel; | 71.57% |
With 1-methyl-pyrrolidin-2-one; sodium carbonate In water at 50℃; for 6h; | 71.57% |
1,3,5-tri-O-benzoyl-2-deoxy-2-fluoro-α-D-arabinofuranose
sevoflurane
Conditions | Yield |
---|---|
With potassium fluoride In various solvent(s) at 95℃; for 1h; Substitution; | 71% |
bis {[2,2,2-trifluoro-1-(trifluoromethyl)ethoxy]methyl} ether
sevoflurane
Conditions | Yield |
---|---|
With hydrogen fluoride at -30 - 70℃; for 1.5h; | 53% |
methyl 3,3,3-trifluoro-2-trifluoromethyl-2-chloromethoxypropionate
sevoflurane
Conditions | Yield |
---|---|
With potassium fluoride In polyethyleneglycol at 90 - 95℃; for 5h; Product distribution / selectivity; Autoclave; | 51.7% |
1,3,5-Trioxan
1,1,1,3',3',3'-hexafluoro-propanol
A
formaldehyde methyl [2,2,2-trifluoro-1-(trifluoromethyl)ethyl] acetal
B
formaldehyde fluoromethyl [2,2,2-trifluoro-1-(trifluoromethyl)ethyl] acetal
C
bis {[2,2,2-trifluoro-1-(trifluoromethyl)ethoxy]methyl} ether
D
sevoflurane
Conditions | Yield |
---|---|
With hydrogen fluoride at 31 - 65℃; under 1275.13 - 2467.75 Torr; for 6h; Inert atmosphere; | A n/a B n/a C n/a D 23% E n/a |
1,3,5-Trioxan
1,1,1,3',3',3'-hexafluoro-propanol
A
formaldehyde fluoromethyl [2,2,2-trifluoro-1-(trifluoromethyl)ethyl] acetal
B
bis {[2,2,2-trifluoro-1-(trifluoromethyl)ethoxy]methyl} ether
C
sevoflurane
Conditions | Yield |
---|---|
With hydrogen fluoride at 56 - 65℃; under 1275.13 - 2467.75 Torr; for 6h; Inert atmosphere; | A n/a B n/a C 23% D n/a |
bis(2-chloromethyl)ether
sevoflurane
Conditions | Yield |
---|---|
With BrF3 |
1,1,1,3,3,3-hexachloro-2-methoxy-propane
sevoflurane
Conditions | Yield |
---|---|
With sodium hydroxide In BrF3 |
methyl 3,3,3-trifluoro-2-hydroxy-2-(trifluoromethyl)propionate
C6H5F7O3
Methyl 3,3,3-trifluoro-2-trifluoromethyl-2-methoxypropionate
A
potassium 3,3,3-trifluoro-2-trifluoromethyl-2-hydroxypropionate
B
MTTMP; potassium salt
C
sevoflurane
D
1,1,1,3,3,3-hexafluoro-2-methoxypropane
Conditions | Yield |
---|---|
With potassium hydroxide; water at 50℃; for 2h; | A 99 %Spectr. B 71 %Spectr. C 89 %Spectr. D 5 %Spectr. |
With water; potassium carbonate at 50℃; |
diethyl-2-(chloromethoxy)malonate
sevoflurane
Conditions | Yield |
---|---|
With sulfur tetrafluoride; hydrogen fluoride In Solkane365 mfc at 23 - 100℃; under 45004.5 Torr; Product distribution / selectivity; |
1,1,1,3,3,3-hexafluoro-2-bromomethoxy-propane
sevoflurane
Conditions | Yield |
---|---|
With potassium fluoride In sulfolane; 2,2'-[1,2-ethanediylbis(oxy)]bisethanol at 85℃; for 6h; | |
With potassium fluoride In sulfolane; 2,2'-[1,2-ethanediylbis(oxy)]bisethanol at 85℃; for 6h; Product distribution / selectivity; |
iodomethyl 2,2,2-trifluoro-1-(trifluoromethyl)ethyl ether
sevoflurane
Conditions | Yield |
---|---|
With potassium fluoride In N,N-dimethyl-formamide; 2,2'-[1,2-ethanediylbis(oxy)]bisethanol at 85℃; for 6h; | |
With potassium fluoride In N,N-dimethyl-formamide; 2,2'-[1,2-ethanediylbis(oxy)]bisethanol at 85℃; for 6h; Product distribution / selectivity; |
Conditions | Yield |
---|---|
trifluorormethanesulfonic acid In dichloromethane at 25℃; for 15h; Product distribution / selectivity; Polyethylene container; | 58 %Chromat. |
at 20℃; for 1h; |
1,1,1,3,3-pentafluorobutane
diethyl-2-(chloromethoxy)malonate
sevoflurane
Conditions | Yield |
---|---|
With sulfur tetrafluoride; hydrogen fluoride at 23 - 100℃; under 45004.5 Torr; Autoclave; |
C4H5FO5
sevoflurane
Conditions | Yield |
---|---|
With sulfur tetrafluoride |
Conditions | Yield |
---|---|
Stage #1: formaldehyd; 1,1,1,3',3',3'-hexafluoro-propanol With hydrogen fluoride In dichloromethane Cooling with ice; Stage #2: With sulfuric acid at 20℃; for 1h; |
sevoflurane
1,1,1,3,3,3-hexafluoroisopropyl chloromethyl ether
Conditions | Yield |
---|---|
In water | 79% |
sevoflurane
fluoromethyl 2,2-difluoro-1-(trifluoromethyl)vinyl ether
Conditions | Yield |
---|---|
With methyllithium In formaldehyde diethyl acetal at -31 - -20℃; Product distribution / selectivity; Inert atmosphere; | 50% |
With lithium hexamethyldisilazane In tetrahydrofuran at -70℃; for 0.25h; Yield given; |
sevoflurane
sodium methylate
Fluoromethyl 2-methoxy-2,2-difluoro-1-(trifluoromethyl)ethyl ether
Conditions | Yield |
---|---|
In methanol 1.) 15-22 deg C, 45 min; 2.) RT 1 3/4 h; 3.) reflux, 2 h; | 4.9 g |
sevoflurane
sodium methylate
A
Fluoromethyl 2-methoxy-2,2-difluoro-1-(trifluoromethyl)ethyl ether
Conditions | Yield |
---|---|
at 35 - 40℃; for 0.5h; Yields of byproduct given; | A n/a B 0.375 g |
sevoflurane
Conditions | Yield |
---|---|
With potassium carbonate; lithium hexamethyldisilazane In tetrahydrofuran at -65 - 0℃; for 0.5h; Yield given; |
sevoflurane
A
Fluoromethyl 2-methoxy-2,2-difluoro-1-(trifluoromethyl)ethyl ether
B
fluoromethyl 2,2-difluoro-1-(trifluoromethyl)vinyl ether
Conditions | Yield |
---|---|
With soda lime at 120℃; for 0.666667h; Product distribution; Mechanism; further time and temperature; also with D2-sevoflurane; |
sevoflurane
Conditions | Yield |
---|---|
With hydrogenchloride; hydrogen fluoride; N-ethyl-N,N-diisopropylamine In 1,1,1,3,3,3-hexafluoroisopropyl chloromethyl ether; water |
1,1,1,3',3',3'-hexafluoro-propanol
sevoflurane
sevoflurane
Conditions | Yield |
---|---|
With aluminum oxide; Trimethylsilanol |
sevoflurane
A
formaldehyde fluoromethyl [2,2,2-trifluoro-1-(trifluoromethyl)ethyl] acetal
B
1,1,1,3',3',3'-hexafluoro-propanol
sevoflurane
bis {[2,2,2-trifluoro-1-(trifluoromethyl)ethoxy]methyl} ether
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