Dayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities
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inquiryWelcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our
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inquiryWith our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufacturin
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inquiryOur company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.O
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inquiryHello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai
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inquiryHenan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod
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inquiryOur Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We
Cas:29706-84-1
Min.Order:10 Kilogram
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Type:Trading Company
inquiryNewCan Biotech Limited was established in 2021 and is primarily engaged in the research, development, production, and sales of sugars, nucleosides, nucleotides, phosphorylated monomers, as well as next-generation antiviral and antitumor drug intermed
Cas:29706-84-1
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inquiryA substitute for perfluorooctanoic acid, mainly used as a surfactant, dispersant, additive, etc Appearance:White solid or Colorless liquid Purity:99.3 % We will ship the goods in a timely manner as required We can provide relevant documents acc
Cas:29706-84-1
Min.Order:4 Kilogram
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inquiryJ&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia
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inquiryWe are one of a few suppliers that can offer custom synthesis service of this product We are specialized in custom synthesis, chemical/pharmaceutical/ pesticides outsourcing and contract research. We are committed to prov
Cas:29706-84-1
Min.Order:100 Gram
FOB Price: $100.0 / 2000.0
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inquiryfactory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B
Cas:29706-84-1
Min.Order:1 Kilogram
FOB Price: $18.0 / 20.0
Type:Trading Company
inquiryShandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W
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Min.Order:1 Gram
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inquiry1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer
Cas:29706-84-1
Min.Order:1 Metric Ton
FOB Price: $1.5
Type:Trading Company
inquiryWuhu Nuovo Chemical Technology Co., Ltd. was established in August 2014, mainly engaged in the development, production and sales of ionic liquids, ribose, nucleosides, nucleotides and related chemicals; Products are mainly used in new energy, new ma
We are a Union of chemistry in China, consists of chemists,engineers, laboratories,factories in China. We organize surplus capacity of R&D and production as well as custom synthesis for chemical products and chemical business project. We are supp
Cas:29706-84-1
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inquiryCangzhou Enke Pharma Tech Co.,ltd. is located in Cangzhou City, Hebei province ,where is a famous petroleum chemical industry city in China. Enke Pharma a high-tech enterprise ,and we are dedicated to developing and manufacturing new api, intermediat
Cas:29706-84-1
Min.Order:1 Kilogram
FOB Price: $300.0 / 400.0
Type:Lab/Research institutions
inquiryLower price, sample is available,SDS test documents are available,large stock in warehouseAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:Fine chemical intermediates, used as the main raw material for the synthe
Cas:29706-84-1
Min.Order:0
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inquiryOur clients, like BASF,CHEMO,Brenntag,ASR,Evonik,Merck and etc.Appearance:COA Storage:in stock Application:MSDS/TDS
TAIHO Unique Advantages:1.We're factory2.Free samples available3.Commodity inspection can be done4.ISO9001,Kosher certifications5.10 years experiences Storage:Store in cool &dry place Package:aluminium foil bag/fiber can/plastic drum Application:comp
Cas:29706-84-1
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Type:Manufacturers
inquiryAnsciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali
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inquiryWe are a trading company aiming at providing high-quality services to customers. Established for many years, with good reputation in the industry Storage:Sealed and preserved Application:Fine chemical intermediates, used as the main raw material for
Cas:29706-84-1
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inquiry3-Azido-3-deoxy-5-O-triphenylmethylthymidine Application:3-Azido-3-deoxy-5-O-triphenylmethylthymidine
Cas:29706-84-1
Min.Order:0
Negotiable
Type:Other
inquirySupply top quality products with a reasonable price Application:api
Thymidine,3'-azido-3'-deoxy-5'-O-(triphenylmethyl)- cas 29706-84-1Appearance:white crystalline powder Storage:Store in dry, dark and ventilated place Package:25KG drum Application:intermediate Transportation:by air, by sea, by express
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Type:Other
inquiryfactory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin
Cas:29706-84-1
Min.Order:0
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Type:Lab/Research institutions
inquiry1. Timely and efficient service to ensure communication with customers2. Produce products of different specifications and sizes according to your requirements.3. Quality procedures and standards recognized by SGS. Advanced plant equipment ensures sta
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inquiryHangzhou ZeErRui Chemical Co., Ltd. is focused on customization, research and development and production of APIs and advanced intermediates, which can effectively compensate for the deficiencies of traditional CRO and CMO. Priority of high-tech barri
Cas:29706-84-1
Min.Order:0
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Type:Lab/Research institutions
inquiryWuhan Xinweiye Chemical Co., Ltd. is mainly engaged in the process development and production of customized synthesis and pharmaceutical intermediates. We have professional researchers in organic synthesis, analytical chemistry and production process
Cas:29706-84-1
Min.Order:0
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Type:Lab/Research institutions
inquiry3-Azido-3-deoxy-5-O-triphenylmethylthymidineAppearance:white to slightly beige crystalline powder Storage:Room temperature Package:as you requested Application:Pharmaceutical intermediates Transportation:By express (Door to door) such as FEDEX, DHL,
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Min.Order:0
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inquiry5'-O-trityl-2,3'-anhydrothymidine
1-(3-azido-2,3-deoxy-5-O-trityl-β-D-erythro-pentofuranosyl)thymine
Conditions | Yield |
---|---|
With lithium azide In N,N-dimethyl-formamide at 100℃; | 96% |
With sodium azide In water; N,N-dimethyl-formamide for 15h; Heating; | 80% |
With sodium azide In dimethyl sulfoxide at 110℃; for 24h; Large scale reaction; | |
Multi-step reaction with 2 steps 1.1: sodium azide / dimethyl sulfoxide / 24 h / 110 °C / Large scale reaction 1.2: 2.5 h / 77 °C / Large scale reaction 2.1: pyridine / 1 h / 70 - 75 °C View Scheme |
3'-azido-2',3'-deoxythymidine
trityl chloride
1-(3-azido-2,3-deoxy-5-O-trityl-β-D-erythro-pentofuranosyl)thymine
Conditions | Yield |
---|---|
With pyridine at 45℃; | 95% |
With pyridine at 70 - 75℃; for 1h; | 41.18 g |
1-(3-azido-2,3-deoxy-5-O-trityl-β-D-erythro-pentofuranosyl)thymine
Conditions | Yield |
---|---|
With sodium azide In N,N-dimethyl-formamide at 20℃; for 24h; | 94% |
1-(2-deoxy-3-O-methanesulfonyl-5-O-trityl-β-D-threo-pentofuranosyl)thymine
1-(3-azido-2,3-deoxy-5-O-trityl-β-D-erythro-pentofuranosyl)thymine
Conditions | Yield |
---|---|
With sodium azide In ethylene glycol at 120℃; for 0.75h; | 87% |
With lithium azide In N,N-dimethyl-formamide at 80℃; for 4h; |
5'-O-trityldeoxyxylothymidine
A
1-(3-Azido-2,3-dideoxy-5-O-trityl-β-D-threo-pentofuranosyl)thymine
B
1-(3-azido-2,3-deoxy-5-O-trityl-β-D-erythro-pentofuranosyl)thymine
Conditions | Yield |
---|---|
With lithium azide; carbon tetrabromide; triphenylphosphine In N,N-dimethyl-formamide for 43h; Ambient temperature; | A n/a B 67% |
1-(2-deoxy-3-O-methanesulfonyl-5-O-trityl-β-D-ribopentofuranosyl)thymine
A
5'-O-trityl-2,3'-anhydrothymidine
B
1-(3-Azido-2,3-dideoxy-5-O-trityl-β-D-threo-pentofuranosyl)thymine
C
1-(3-azido-2,3-deoxy-5-O-trityl-β-D-erythro-pentofuranosyl)thymine
Conditions | Yield |
---|---|
With lithium azide In N,N-dimethyl-formamide at 100℃; for 5h; | A 15% B 48% C 5% |
With lithium azide In N,N-dimethyl-formamide at 150℃; for 0.5h; | A 25% B 25% C 32% |
5'-O-tritylthymidine
1-(3-azido-2,3-deoxy-5-O-trityl-β-D-erythro-pentofuranosyl)thymine
Conditions | Yield |
---|---|
With sodium azide; triethylamine; tetra-(n-butyl)ammonium iodide In N,N-dimethyl-formamide for 12h; Heating; | 47% |
Multi-step reaction with 3 steps 1: 95 percent / pyridine / 15 h / 0 °C 2: 85 percent / potassium phthalimide / dimethylformamide; H2O / 3 h / 90 °C 3: 80 percent / NaN3 / dimethylformamide; H2O / 15 h / Heating View Scheme |
1-(2-deoxy-3-O-methanesulfonyl-5-O-trityl-β-D-ribopentofuranosyl)thymine
A
6,3'-Imino-1-(2,3-dideoxy-5-O-trityl-β-D-threo-pentofuranosyl)thymine
B
1-(3-azido-2,3-deoxy-5-O-trityl-β-D-erythro-pentofuranosyl)thymine
Conditions | Yield |
---|---|
With sodium azide In N,N-dimethyl-formamide for 24h; Heating; | A 43% B 41% |
1-(2-deoxy-3-O-methanesulfonyl-5-O-trityl-β-D-ribopentofuranosyl)thymine
1-(3-azido-2,3-deoxy-5-O-trityl-β-D-erythro-pentofuranosyl)thymine
Conditions | Yield |
---|---|
In N,N-dimethyl-formamide for 24h; Heating; | 43% |
1-(3'-iodo-2',3'-dideoxy-5'-O-trityl-β-D-erythro-pentofuranosyl)thymine
A
1-(3-Azido-2,3-dideoxy-5-O-trityl-β-D-threo-pentofuranosyl)thymine
B
1-(3-azido-2,3-deoxy-5-O-trityl-β-D-erythro-pentofuranosyl)thymine
Conditions | Yield |
---|---|
With sodium azide In N,N-dimethyl-formamide at 100℃; for 0.5h; Yield given. Yields of byproduct given. Title compound not separated from byproducts; |
5'-O-trityldeoxyxylothymidine
1-(3-azido-2,3-deoxy-5-O-trityl-β-D-erythro-pentofuranosyl)thymine
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: pyridine / 9 h / 0 - 20 °C 2: LiN3 / dimethylformamide / 4 h / 80 °C View Scheme |
1-(2-deoxy-3-O-methanesulfonyl-5-O-trityl-β-D-ribopentofuranosyl)thymine
1-(3-azido-2,3-deoxy-5-O-trityl-β-D-erythro-pentofuranosyl)thymine
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: 85 percent / potassium phthalimide / dimethylformamide; H2O / 3 h / 90 °C 2: 80 percent / NaN3 / dimethylformamide; H2O / 15 h / Heating View Scheme | |
Multi-step reaction with 2 steps 1: sodium carbonate / methanol; water / Reflux 2: lithium azide / N,N-dimethyl-formamide / 100 °C View Scheme |
1-(3-azido-2,3-deoxy-5-O-trityl-β-D-erythro-pentofuranosyl)thymine
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: water / 70 - 97 °C 2: hydrogenchloride / water / 75 °C / Large scale reaction 3: pyridine / 1 h / 70 - 75 °C View Scheme |
AZT guanidine salt
1-(3-azido-2,3-deoxy-5-O-trityl-β-D-erythro-pentofuranosyl)thymine
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: hydrogenchloride / water / 75 °C / Large scale reaction 2: pyridine / 1 h / 70 - 75 °C View Scheme |
2'-bromothymidine
1-(3-azido-2,3-deoxy-5-O-trityl-β-D-erythro-pentofuranosyl)thymine
Conditions | Yield |
---|---|
Multi-step reaction with 5 steps 1: pyridine / 60 °C 2: pyridine / dichloromethane / 0 - 5 °C 3: hydrogen; triethylamine / methanol / 20 - 40 °C 4: sodium carbonate / methanol; water / Reflux 5: lithium azide / N,N-dimethyl-formamide / 100 °C View Scheme |
trityl chloride
1-(3-azido-2,3-deoxy-5-O-trityl-β-D-erythro-pentofuranosyl)thymine
Conditions | Yield |
---|---|
Multi-step reaction with 5 steps 1: pyridine / 60 °C 2: pyridine / dichloromethane / 0 - 5 °C 3: hydrogen; triethylamine / methanol / 20 - 40 °C 4: sodium carbonate / methanol; water / Reflux 5: lithium azide / N,N-dimethyl-formamide / 100 °C View Scheme |
1-(3-azido-2,3-deoxy-5-O-trityl-β-D-erythro-pentofuranosyl)thymine
Conditions | Yield |
---|---|
Multi-step reaction with 4 steps 1: pyridine / dichloromethane / 0 - 5 °C 2: hydrogen; triethylamine / methanol / 20 - 40 °C 3: sodium carbonate / methanol; water / Reflux 4: lithium azide / N,N-dimethyl-formamide / 100 °C View Scheme |
1-(3-azido-2,3-deoxy-5-O-trityl-β-D-erythro-pentofuranosyl)thymine
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: hydrogen; triethylamine / methanol / 20 - 40 °C 2: sodium carbonate / methanol; water / Reflux 3: lithium azide / N,N-dimethyl-formamide / 100 °C View Scheme |
1-(3-azido-2,3-deoxy-5-O-trityl-β-D-erythro-pentofuranosyl)thymine
3'-azido-2',3'-deoxythymidine
Conditions | Yield |
---|---|
With silica gel; trifluoroacetic acid In methanol; chloroform | 95% |
With hydrogenchloride In methanol; water at 20℃; for 3h; | 95% |
With hydrogenchloride In acetic acid at 20℃; for 2h; | 49% |
With sodium periodate In acetone at 50℃; for 20h; |
1-(3-azido-2,3-deoxy-5-O-trityl-β-D-erythro-pentofuranosyl)thymine
3'-amino-3'-deoxy-5'-O-triphenylmethyl-β-D-thymidine
Conditions | Yield |
---|---|
With sodium tetrahydroborate In isopropyl alcohol at 82℃; for 14h; | 93% |
With thiophenol; triethylamine; tin(ll) chloride In acetonitrile for 0.5h; Ambient temperature; | 85% |
With ammonium formate; palladium on activated charcoal In methanol for 2.5h; Heating; | 76% |
N-methoxy-N-methyl-2-propynamide
1-(3-azido-2,3-deoxy-5-O-trityl-β-D-erythro-pentofuranosyl)thymine
Conditions | Yield |
---|---|
With N-ethyl-N,N-diisopropylamine In acetonitrile for 3h; Inert atmosphere; Reflux; stereoselective reaction; | 91% |
N,N-dimethylformamide diethyl diacetal
1-(3-azido-2,3-deoxy-5-O-trityl-β-D-erythro-pentofuranosyl)thymine
Conditions | Yield |
---|---|
In N,N-dimethyl-formamide at 100℃; for 24h; | 82% |
allyl bromide
1-(3-azido-2,3-deoxy-5-O-trityl-β-D-erythro-pentofuranosyl)thymine
Conditions | Yield |
---|---|
With potassium carbonate In N,N-dimethyl-formamide at 60℃; for 4h; | 78% |
2-(2-(prop-2-yn-1-yloxy)ethoxy)ethyl methanesulfonate
1-(3-azido-2,3-deoxy-5-O-trityl-β-D-erythro-pentofuranosyl)thymine
Conditions | Yield |
---|---|
Stage #1: 2-(2-(prop-2-yn-1-yloxy)ethoxy)ethyl methanesulfonate With tetrabutyl ammonium fluoride In tert-butyl alcohol at 100℃; for 0.333333h; Stage #2: 1-(3-azido-2,3-deoxy-5-O-trityl-β-D-erythro-pentofuranosyl)thymine With copper(II) sulfate; sodium L-ascorbate In water; tert-butyl alcohol at 20℃; for 0.5h; Huisgen 1,3-dipolar cycloaddition; Further stages.; | 73% |
prenyl bromide
1-(3-azido-2,3-deoxy-5-O-trityl-β-D-erythro-pentofuranosyl)thymine
Conditions | Yield |
---|---|
With sodium hydride In N,N-dimethyl-formamide at 60℃; for 4h; | 64% |
5'-O-trityl-2,3'-anhydrothymidine
1-(3-azido-2,3-deoxy-5-O-trityl-β-D-erythro-pentofuranosyl)thymine
A
3'-azido-2',3'-deoxythymidine
B
thymin
Conditions | Yield |
---|---|
With potassium carbonate In dimethyl sulfoxide at 108℃; for 24h; | A 31 %Chromat. B 16 %Chromat. C 8.6% |
1-(3-azido-2,3-deoxy-5-O-trityl-β-D-erythro-pentofuranosyl)thymine
3'-amino-3'-deoxythymidine
Conditions | Yield |
---|---|
With hydrogen; acetic acid; palladium on activated charcoal Yield given. Multistep reaction; | |
Multi-step reaction with 2 steps 1: 93 percent / sodium borohydride / propan-2-ol / 14 h / 82 °C 2: Dowex 50Wx2 (H+) / methanol; H2O View Scheme | |
Multi-step reaction with 2 steps 1: H2 / 10percent Pd-C / ethanol / 24 h / 825.07 Torr 2: 98percent HCO2H / 0.08 h / 70 °C View Scheme |
1-(3-azido-2,3-deoxy-5-O-trityl-β-D-erythro-pentofuranosyl)thymine
Conditions | Yield |
---|---|
With 1-methyl-1H-imidazole; trichlorophosphate In pyridine; acetonitrile for 2h; Ambient temperature; |
1-(3-azido-2,3-deoxy-5-O-trityl-β-D-erythro-pentofuranosyl)thymine
Conditions | Yield |
---|---|
With 1-methyl-1H-imidazole; hydroxylamine hydrochloride; triethylamine; trichlorophosphate 1.) pyridine, RT, 30 min, 2.) pyridine, H2O, RT, 7 h; Multistep reaction; |
1-(3-azido-2,3-deoxy-5-O-trityl-β-D-erythro-pentofuranosyl)thymine
trimethylphosphane
Conditions | Yield |
---|---|
In toluene for 1h; Ambient temperature; |
2-(2-(prop-2-yn-1-yloxy)ethoxy)ethyl methanesulfonate
1-(3-azido-2,3-deoxy-5-O-trityl-β-D-erythro-pentofuranosyl)thymine
Conditions | Yield |
---|---|
Stage #1: 2-(2-(prop-2-yn-1-yloxy)ethoxy)ethyl methanesulfonate With tetrabutylammonium bicarbonate In acetonitrile; tert-butyl alcohol at 100℃; for 0.333333h; Stage #2: 1-(3-azido-2,3-deoxy-5-O-trityl-β-D-erythro-pentofuranosyl)thymine With copper(II) sulfate; sodium L-ascorbate In water; acetonitrile; tert-butyl alcohol at 20℃; for 0.166667h; Huisgen 1,3-dipolar cycloaddition; Further stages.; |
1-(3-azido-2,3-deoxy-5-O-trityl-β-D-erythro-pentofuranosyl)thymine
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1.1: 49 percent / HCl / acetic acid / 2 h / 20 °C 2.1: TBAF / 2-methyl-propan-2-ol / 0.33 h / 100 °C 2.2: 74 percent / CuSO4*5H2O; sodium ascorbate / H2O; 2-methyl-propan-2-ol / 0.5 h / 20 °C View Scheme |
1-(3-azido-2,3-deoxy-5-O-trityl-β-D-erythro-pentofuranosyl)thymine
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: H2 / 10 percent Pd/C / ethanol / 4 h 2: CH2Cl2 / 2 h / 20 °C View Scheme |
1-(3-azido-2,3-deoxy-5-O-trityl-β-D-erythro-pentofuranosyl)thymine
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: toluene / 1 h / Ambient temperature 2: toluene / 5 h / -20 - 20 °C View Scheme |
1-(3-azido-2,3-deoxy-5-O-trityl-β-D-erythro-pentofuranosyl)thymine
1-((E)-3-Ethoxy-acryloyl)-3-[(2S,3S,5R)-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-2-trityloxymethyl-tetrahydro-furan-3-yl]-urea
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: 85 percent / SnCl2, PhSH, Et3N / acetonitrile / 0.5 h / Ambient temperature 2: 90 percent / benzene; dimethylformamide / 2 h / Ambient temperature View Scheme |
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