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Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch

Chloromethyl ethyl ether

Cas:3188-13-4

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

Chloromethyl ethyl ether

Cas:3188-13-4

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

CAS NO.:3188-13-4

Cas:3188-13-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

Chloromethyl ethyl ether

Cas:3188-13-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Shanghai Massive Chemical Technology Co., Ltd.

Massive Chemical is certified with ISO9001 and ISO14001 manufacturer for this product. We will offer all documents as requirement for the materials which includes, Certificate of Analysis, Material Safety Data Sheet, and Method of Analysis and

Chloromethyl ethyl ether

Cas:3188-13-4

Min.Order:1 Gram

FOB Price: $1.0

Type:Lab/Research institutions

inquiry

Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung, LG, Merck, Thermo Fisher Scientific and so o

3188-13-4 Chloromethyl ethyl ether

Cas:3188-13-4

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Greenutra Resource Inc

chloromethyl ethyl etherAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air

chloromethyl ethyl ether

Cas:3188-13-4

Min.Order:0

Negotiable

Type:Trading Company

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Kono Chem Co.,Ltd

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air Port:Beijing or Guangzhou

chloromethyl ethyl ether

Cas:3188-13-4

Min.Order:0

Negotiable

Type:Other

inquiry

Wuhan Fortuna Chemical Co.,Ltd

Best service,high quality and cheap price. Storage:Keep away from heat,sparks and flames. Package:25kg/50kg/200kg drum or Customer demand Application:Used as pharmaceutical intermediates Transportation:BY sea/air or by courier

chloromethyl ethyl ether

Cas:3188-13-4

Min.Order:0

Negotiable

Type:Trading Company

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Henan Allgreen Chemical Co.,Ltd

high quality Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea

chloroMethyl ethyl ether

Cas:3188-13-4

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Aecochem Corp.

Our clients, like BASF,CHEMO,Brenntag,ASR,Evonik,Merck and etc.Appearance:COA Storage:in stock Application:MSDS/TDS

Chloromethyl Ethyl Ether

Cas:3188-13-4

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

Product Description Description & Specification Category Pharmaceutical Raw Materials, Fine Chemicals, Bulk drug Standard Medical standard

factory supply CAS 3188-13-4 with competitive price

Cas:3188-13-4

Min.Order:1 Kilogram

FOB Price: $112.0

Type:Trading Company

inquiry

Antimex Chemical Limied

Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali

ChloroMethyl ethyl ether

Cas:3188-13-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hunan Russell Chemicals Technology Co.,Ltd

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:Foil bag; Drum; Plastic bottle Application:Pharma;Industry;Agricultural Transportation:by sea or air Port:any port in China

Chloromethoxyethane 3188-13-4

Cas:3188-13-4

Min.Order:0

Negotiable

Type:Trading Company

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HWRK Chem

in storeAppearance:Colorless - very pale yellow transparent liquid Package:250g Application:Organic Chemicals

Chloromethyl Ethyl Ether

Cas:3188-13-4

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Amadis Chemical Co., Ltd.

1.Professional synthesis laboratory and production base. 2.Strong synthesis team and service team. 3.Professional data management system. 4.We provide the professional test date and product information ,ex. HNMR ,CNMR,FNMR, HPLC/G

Amadis Chemical offer CAS#3188-13-4;CAT#A821042

Cas:3188-13-4

Min.Order:10 Milligram

Negotiable

Type:Lab/Research institutions

inquiry

HENAN SUNLAKE ENTERPRISE CORPORATION

Chloromethyl ethyl ether

Cas:3188-13-4

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Changzhou Extraordinary Pharmatech co.,LTD

Changzhou Extraordinary Pharmatech co., LTD. As a leading chemical manufacturer and supplier in China.DAS authentication is passed.We can provide the popular precursor chemicals, we have our own strong R & D team, have our own laboratories and fa

Chloromethyl Ethyl Ether

Cas:3188-13-4

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Xiamen BaiFuchem Co.,Ltd

BaiFuChem is a Professional chemical raw material supplier in China, our main products include Biochemical , Pharma Intermediate and Organic chemical etc. BaiFuChem have wealth of products,experience , expertise and state-of-the-art

Best price Chloromethyl Ethyl Ether

Cas:3188-13-4

Min.Order:1 Kilogram

Negotiable

Type:Other

inquiry

Zouping Mingxing Chemical Co.,Ltd.

Product Name: Chloromethyl ethyl ether Molecular Formula: C3H7ClO Molecular Weight: 94.54 Moisture: ≤0.50%Appearance:colorless transparent liquid Package:200Kg/drum Application:As intermediate in organic synthesis

Chloromethyl ethyl ether

Cas:3188-13-4

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Hangzhou Yierdechem Co. Ltd

With about ten years experiences in the field of pharmaceutical chemicals, Yierdechem has established solid business cooperation relationships with many large companys worldwide.As a leading supplier of API and pharmaceutical intermediates, holds its

Chloromethyl ethyl ether

Cas:3188-13-4

Min.Order:0

Negotiable

Type:Other

inquiry

Nanjing Chemlin Chemical Co., Ltd.

please contact us to confirm the required quantity and quote, we will provide you with COA,NMR,HPLC and other relevant informationAppearance:Colorless liquid Storage:Store in a cool place. Keep container tightly closed in a dry and well-ventilated pl

chloromethyl ethyl ether

Cas:3188-13-4

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Capot Chemical Co., Ltd.

At Capot,We can synthesize and purify your complex molecules from 100 gram to 10 tons.Appearance:Clear colorless to light yellow liquid Storage:Dry,Seal and Cool place Package:1G,5G,10G,25G,100G,250G,500G,1KG,5KG,10KG,25KG,50KG,100KG,150KG,200KG. App

Chloromethyl Ethyl Ether

Cas:3188-13-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Kunshan Yalong Trading Co,.Ltd

Chloromethyl ethyl ether Package:250kg/drum Transportation:By sea,by air Port:as per clients' request

Chloromethyl ethyl ether

Cas:3188-13-4

Min.Order:1 Metric Ton

Negotiable

Type:Trading Company

inquiry

Shaanxi Mingqi Chemical Co., Ltd

Known for its best quality and competitve price, this chemicals we offered is widely appreciated by our customers. Our advantages:1, High quality with competitive price:1) Standard:BP/USP/EP/Enterprise standard2) All Purity≥99%3) We are manufacturer

chloromethyl ethyl ether

Cas:3188-13-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Skyrun Industrial Co.,Ltd

SkyRun Industrial CO.,LTD is a leading chemical producer in China. We supply Intermediate, Agro-Chemical and Petrol Chemicals for different usage.SkyRun Industrial CO.,LTD is a leading chemical producer in China. We supply Intermediate, Agro-Chemic

Chloromethyl ethyl ether

Cas:3188-13-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

GZ HONESTCHEM CO., LTD

chloromethyl ethyl etherAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air

chloromethyl ethyl ether

Cas:3188-13-4

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Wuxi Morality Chemical Co., Ltd

Do best quality products, erect the morality model Application:please email us, thanks

Chloromethyl ethyl ether

Cas:3188-13-4

Min.Order:0

Negotiable

Type:Other

inquiry

MENGNA

Chloromethyl ethyl ether

Cas:3188-13-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Debye Scientific

Debyesci is here who supplied several kinds of chemical products to global pharmaceutical, drug discovery, agrochemical and biotechnology industries for four yearsOur key scientific leadership team has gained experience in top research and developmen

Chloromethylethylether

Cas:3188-13-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Synthetic route

formaldehyde diethyl acetal
462-95-3

formaldehyde diethyl acetal

ethyl chloromethyl ether
3188-13-4

ethyl chloromethyl ether

Conditions
ConditionsYield
With benzoyl chloride; phosphotungstic acid at 60 - 65℃;78%
With acetyl chloride; zinc trifluoromethanesulfonate at 24 - 32℃; for 17h;
With sulfuric acid; acetyl chloride at 40℃; for 3h; Inert atmosphere;
With acetyl chloride; zinc dibromide In toluene at 20 - 45℃; for 4h;
formaldehyd
50-00-0

formaldehyd

ethanol
64-17-5

ethanol

ethyl chloromethyl ether
3188-13-4

ethyl chloromethyl ether

Conditions
ConditionsYield
With hydrogenchloride
With hydrogenchloride
(i) aq. HCl, (ii) /BRN= 1718733/, HCl; Multistep reaction;
formaldehyd
50-00-0

formaldehyd

ethyl chloromethyl ether
3188-13-4

ethyl chloromethyl ether

Conditions
ConditionsYield
With hydrogenchloride; ethanol
1,3,5-Trioxan
110-88-3

1,3,5-Trioxan

ethanol
64-17-5

ethanol

ethyl chloromethyl ether
3188-13-4

ethyl chloromethyl ether

Conditions
ConditionsYield
With hydrogenchloride
1-ethoxy-1-(ethylthio)methane
54699-20-6

1-ethoxy-1-(ethylthio)methane

ethyl chloromethyl ether
3188-13-4

ethyl chloromethyl ether

Conditions
ConditionsYield
With acetyl chloride at 45 - 55℃; for 144h;
ethanol
64-17-5

ethanol

polyoxymethylene

polyoxymethylene

ethyl chloromethyl ether
3188-13-4

ethyl chloromethyl ether

Conditions
ConditionsYield
With hydrogenchloride
With hydrogenchloride
With hydrogenchloride
1-ethoxymethoxy-2,4-dichloro-benzene
829-59-4

1-ethoxymethoxy-2,4-dichloro-benzene

chlorine
7782-50-5

chlorine

A

bis(2,4-dichlorophenoxy)methane
35412-53-4

bis(2,4-dichlorophenoxy)methane

B

2,4-dichlorophenoxymethyl chloride
13543-09-4

2,4-dichlorophenoxymethyl chloride

C

2,4-dichlorophenol
120-83-2

2,4-dichlorophenol

D

ethyl chloromethyl ether
3188-13-4

ethyl chloromethyl ether

Conditions
ConditionsYield
at 200℃;
formaldehyde diethyl acetal
462-95-3

formaldehyde diethyl acetal

A

chloroethane
75-00-3

chloroethane

B

ethyl chloromethyl ether
3188-13-4

ethyl chloromethyl ether

Conditions
ConditionsYield
Stage #1: formaldehyde diethyl acetal With dichloromethane; tungsten(VI) chloride In Chloroform-D at 20℃; for 288h;
Stage #2: With water In Chloroform-D
formaldehyde diethyl acetal
462-95-3

formaldehyde diethyl acetal

acetyl chloride
75-36-5

acetyl chloride

ethyl chloromethyl ether
3188-13-4

ethyl chloromethyl ether

Conditions
ConditionsYield
With Zinc chloride
2,4,5-tribromo-1H-imidazole
2034-22-2

2,4,5-tribromo-1H-imidazole

ethyl chloromethyl ether
3188-13-4

ethyl chloromethyl ether

2,4,5-tribromo-1-(ethoxymethyl)-1H-imidazole
22927-65-7

2,4,5-tribromo-1-(ethoxymethyl)-1H-imidazole

Conditions
ConditionsYield
With triethylamine In benzene for 2h; Ambient temperature;100%
With sodium carbonate In N,N-dimethyl-formamide100%
With triethylamine In benzene Ambient temperature;100%
(2S,3R,4S,5R,6R)-3,4,5-tris(benzyloxy)-6-[(benzyloxy)methyl]tetrahydro-2H-pyran-2-thiol
72174-24-4, 53269-97-9

(2S,3R,4S,5R,6R)-3,4,5-tris(benzyloxy)-6-[(benzyloxy)methyl]tetrahydro-2H-pyran-2-thiol

ethyl chloromethyl ether
3188-13-4

ethyl chloromethyl ether

ethoxymethyl 2,3,4,6-tetra-O-benzyl-1-deoxy-1-thio-β-D-glucopyranoside

ethoxymethyl 2,3,4,6-tetra-O-benzyl-1-deoxy-1-thio-β-D-glucopyranoside

Conditions
ConditionsYield
With triethylamine In dichloromethane Condensation;100%
ethyl chloromethyl ether
3188-13-4

ethyl chloromethyl ether

1-bromo-4-(ethoxymethoxy)benzene
152565-23-6

1-bromo-4-(ethoxymethoxy)benzene

Conditions
ConditionsYield
Stage #1: 4-bromo-phenol With sodium hydride In DMF (N,N-dimethyl-formamide) at 0℃; for 0.666667h;
Stage #2: ethyl chloromethyl ether In DMF (N,N-dimethyl-formamide) at 0 - 20℃; for 0.25h;
100%
3,5-dichloro-2-iodophenol
1028332-19-5

3,5-dichloro-2-iodophenol

ethyl chloromethyl ether
3188-13-4

ethyl chloromethyl ether

1,5-dichloro-3-(ethoxymethoxy)-2-iodobenzene
1028332-20-8

1,5-dichloro-3-(ethoxymethoxy)-2-iodobenzene

Conditions
ConditionsYield
With caesium carbonate In N,N-dimethyl-formamide at 20℃; for 2h;100%
With caesium carbonate In N,N-dimethyl-formamide at 20℃; for 2h;100%
With potassium carbonate In N,N-dimethyl-formamide at 20℃; for 12h;90%
With caesium carbonate In N,N-dimethyl-formamide at 20℃; for 3h;
With caesium carbonate In N,N-dimethyl-formamide at 20℃; for 22h;
2-hydroxy-3-bromobenzaldehyde
1829-34-1

2-hydroxy-3-bromobenzaldehyde

ethyl chloromethyl ether
3188-13-4

ethyl chloromethyl ether

C10H11BrO3
1138152-16-5

C10H11BrO3

Conditions
ConditionsYield
With sodium hydride In tetrahydrofuran at 0 - 20℃; for 3h;100%
C16H25O5PolSSi

C16H25O5PolSSi

ethyl chloromethyl ether
3188-13-4

ethyl chloromethyl ether

C19H31O6PolSSi

C19H31O6PolSSi

Conditions
ConditionsYield
With tetra-(n-butyl)ammonium iodide; 1,8-diazabicyclo[5.4.0]undec-7-ene In N,N-dimethyl-formamide at 23℃; for 12h; Inert atmosphere; solid phase reaction;100%
5,7-dihydroxy-2,2-dimethyl-4H-benzo[d][1,3]dioxin-4-one
137571-73-4

5,7-dihydroxy-2,2-dimethyl-4H-benzo[d][1,3]dioxin-4-one

ethyl chloromethyl ether
3188-13-4

ethyl chloromethyl ether

C16H22O7
1201848-91-0

C16H22O7

Conditions
ConditionsYield
With tetra-(n-butyl)ammonium iodide; N-ethyl-N,N-diisopropylamine In dichloromethane at 23℃; Inert atmosphere;100%
formaldehyde diethyl acetal
462-95-3

formaldehyde diethyl acetal

ethyl chloromethyl ether
3188-13-4

ethyl chloromethyl ether

Conditions
ConditionsYield
With benzoyl chloride; phosphotungstic acid at 60 - 65℃;78%
With acetyl chloride; zinc trifluoromethanesulfonate at 24 - 32℃; for 17h;
With sulfuric acid; acetyl chloride at 40℃; for 3h; Inert atmosphere;
With acetyl chloride; zinc dibromide In toluene at 20 - 45℃; for 4h;
Stage #1: formaldehyde diethyl acetal With zinc(II) chloride at 15 - 25℃; for 0.216667h;
Stage #2: With acetyl chloride at 20 - 35℃; for 2h;
formaldehyd
50-00-0

formaldehyd

ethanol
64-17-5

ethanol

ethyl chloromethyl ether
3188-13-4

ethyl chloromethyl ether

Conditions
ConditionsYield
With hydrogenchloride
With hydrogenchloride
(i) aq. HCl, (ii) /BRN= 1718733/, HCl; Multistep reaction;
formaldehyd
50-00-0

formaldehyd

ethyl chloromethyl ether
3188-13-4

ethyl chloromethyl ether

Conditions
ConditionsYield
With hydrogenchloride; ethanol
1,3,5-Trioxan
110-88-3

1,3,5-Trioxan

ethanol
64-17-5

ethanol

ethyl chloromethyl ether
3188-13-4

ethyl chloromethyl ether

Conditions
ConditionsYield
With hydrogenchloride
1-ethoxy-1-(ethylthio)methane
54699-20-6

1-ethoxy-1-(ethylthio)methane

ethyl chloromethyl ether
3188-13-4

ethyl chloromethyl ether

Conditions
ConditionsYield
With acetyl chloride at 45 - 55℃; for 144h;
ethanol
64-17-5

ethanol

polyoxymethylene

polyoxymethylene

ethyl chloromethyl ether
3188-13-4

ethyl chloromethyl ether

Conditions
ConditionsYield
With hydrogenchloride
With hydrogenchloride
With hydrogenchloride
1-ethoxymethoxy-2,4-dichloro-benzene
829-59-4

1-ethoxymethoxy-2,4-dichloro-benzene

chlorine
7782-50-5

chlorine

A

bis(2,4-dichlorophenoxy)methane
35412-53-4

bis(2,4-dichlorophenoxy)methane

B

2,4-dichlorophenoxymethyl chloride
13543-09-4

2,4-dichlorophenoxymethyl chloride

C

2,4-dichlorophenol
120-83-2

2,4-dichlorophenol

D

ethyl chloromethyl ether
3188-13-4

ethyl chloromethyl ether

Conditions
ConditionsYield
at 200℃;
formaldehyde diethyl acetal
462-95-3

formaldehyde diethyl acetal

A

chloroethane
75-00-3

chloroethane

B

ethyl chloromethyl ether
3188-13-4

ethyl chloromethyl ether

Conditions
ConditionsYield
Stage #1: formaldehyde diethyl acetal With dichloromethane; tungsten(VI) chloride In Chloroform-D at 20℃; for 288h;
Stage #2: With water In Chloroform-D
formaldehyde diethyl acetal
462-95-3

formaldehyde diethyl acetal

acetyl chloride
75-36-5

acetyl chloride

ethyl chloromethyl ether
3188-13-4

ethyl chloromethyl ether

Conditions
ConditionsYield
With Zinc chloride
2,4,5-tribromo-1H-imidazole
2034-22-2

2,4,5-tribromo-1H-imidazole

ethyl chloromethyl ether
3188-13-4

ethyl chloromethyl ether

2,4,5-tribromo-1-(ethoxymethyl)-1H-imidazole
22927-65-7

2,4,5-tribromo-1-(ethoxymethyl)-1H-imidazole

Conditions
ConditionsYield
With triethylamine In benzene for 2h; Ambient temperature;100%
With sodium carbonate In N,N-dimethyl-formamide100%
With triethylamine In benzene Ambient temperature;100%
(2S,3R,4S,5R,6R)-3,4,5-tris(benzyloxy)-6-[(benzyloxy)methyl]tetrahydro-2H-pyran-2-thiol
72174-24-4, 53269-97-9

(2S,3R,4S,5R,6R)-3,4,5-tris(benzyloxy)-6-[(benzyloxy)methyl]tetrahydro-2H-pyran-2-thiol

ethyl chloromethyl ether
3188-13-4

ethyl chloromethyl ether

ethoxymethyl 2,3,4,6-tetra-O-benzyl-1-deoxy-1-thio-β-D-glucopyranoside

ethoxymethyl 2,3,4,6-tetra-O-benzyl-1-deoxy-1-thio-β-D-glucopyranoside

Conditions
ConditionsYield
With triethylamine In dichloromethane Condensation;100%
ethyl chloromethyl ether
3188-13-4

ethyl chloromethyl ether

1-bromo-4-(ethoxymethoxy)benzene
152565-23-6

1-bromo-4-(ethoxymethoxy)benzene

Conditions
ConditionsYield
Stage #1: 4-bromo-phenol With sodium hydride In DMF (N,N-dimethyl-formamide) at 0℃; for 0.666667h;
Stage #2: ethyl chloromethyl ether In DMF (N,N-dimethyl-formamide) at 0 - 20℃; for 0.25h;
100%
3,5-dichloro-2-iodophenol
1028332-19-5

3,5-dichloro-2-iodophenol

ethyl chloromethyl ether
3188-13-4

ethyl chloromethyl ether

1,5-dichloro-3-(ethoxymethoxy)-2-iodobenzene
1028332-20-8

1,5-dichloro-3-(ethoxymethoxy)-2-iodobenzene

Conditions
ConditionsYield
With caesium carbonate In N,N-dimethyl-formamide at 20℃; for 2h;100%
With caesium carbonate In N,N-dimethyl-formamide at 20℃; for 2h;100%
With potassium carbonate In N,N-dimethyl-formamide at 20℃; for 12h;90%
With caesium carbonate In N,N-dimethyl-formamide at 20℃; for 3h;
With caesium carbonate In N,N-dimethyl-formamide at 20℃; for 22h;
2-hydroxy-3-bromobenzaldehyde
1829-34-1

2-hydroxy-3-bromobenzaldehyde

ethyl chloromethyl ether
3188-13-4

ethyl chloromethyl ether

C10H11BrO3
1138152-16-5

C10H11BrO3

Conditions
ConditionsYield
With sodium hydride In tetrahydrofuran at 0 - 20℃; for 3h;100%
C16H25O5PolSSi

C16H25O5PolSSi

ethyl chloromethyl ether
3188-13-4

ethyl chloromethyl ether

C19H31O6PolSSi

C19H31O6PolSSi

Conditions
ConditionsYield
With tetra-(n-butyl)ammonium iodide; 1,8-diazabicyclo[5.4.0]undec-7-ene In N,N-dimethyl-formamide at 23℃; for 12h; Inert atmosphere; solid phase reaction;100%
5,7-dihydroxy-2,2-dimethyl-4H-benzo[d][1,3]dioxin-4-one
137571-73-4

5,7-dihydroxy-2,2-dimethyl-4H-benzo[d][1,3]dioxin-4-one

ethyl chloromethyl ether
3188-13-4

ethyl chloromethyl ether

C16H22O7
1201848-91-0

C16H22O7

Conditions
ConditionsYield
With tetra-(n-butyl)ammonium iodide; N-ethyl-N,N-diisopropylamine In dichloromethane at 23℃; Inert atmosphere;100%
acide 2,4,6-trihydroxybenzoique
83-30-7

acide 2,4,6-trihydroxybenzoique

ethyl chloromethyl ether
3188-13-4

ethyl chloromethyl ether

C16H22O7
1201848-91-0

C16H22O7

Conditions
ConditionsYield
Stage #1: acide 2,4,6-trihydroxybenzoique With trifluoroacetic acid; trifluoroacetic anhydride In acetone at 23℃; for 12h;
Stage #2: ethyl chloromethyl ether With N-ethyl-N,N-diisopropylamine; tetra-(n-butyl)ammonium iodide In dichloromethane; acetone at 23℃; for 12h;
100%
2,4-Dihydroxybenzaldehyde
95-01-2

2,4-Dihydroxybenzaldehyde

ethyl chloromethyl ether
3188-13-4

ethyl chloromethyl ether

2,4-bis(ethoxymethoxy)benzaldehyde
128837-29-6

2,4-bis(ethoxymethoxy)benzaldehyde

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 0 - 20℃; for 12h;99%
With potassium carbonate In acetone for 1.5h; Heating;4 g
ethyl ester of trans-4-hydroxy-3,5-di-tert-butylcinnamic acid
147167-96-2

ethyl ester of trans-4-hydroxy-3,5-di-tert-butylcinnamic acid

ethyl chloromethyl ether
3188-13-4

ethyl chloromethyl ether

(E)-3-(3,5-Di-tert-butyl-4-ethoxymethoxy-phenyl)-acrylic acid ethyl ester

(E)-3-(3,5-Di-tert-butyl-4-ethoxymethoxy-phenyl)-acrylic acid ethyl ester

Conditions
ConditionsYield
With sodium hydride In N,N-dimethyl-formamide99%
2-(dimethylamino)ethyl acetate
1421-89-2

2-(dimethylamino)ethyl acetate

ethyl chloromethyl ether
3188-13-4

ethyl chloromethyl ether

(2-acetoxy-ethyl)-ethoxymethyl-dimethyl-ammonium; chloride

(2-acetoxy-ethyl)-ethoxymethyl-dimethyl-ammonium; chloride

Conditions
ConditionsYield
In hexane at 20℃; for 0.166667h; Menschutkin reaction;99%
In hexane at 20℃; Menschutkin reaction;
C26H36O4Si
1200831-59-9

C26H36O4Si

ethyl chloromethyl ether
3188-13-4

ethyl chloromethyl ether

C29H42O5Si
1200831-34-0

C29H42O5Si

Conditions
ConditionsYield
With tetra-(n-butyl)ammonium iodide; N-ethyl-N,N-diisopropylamine In dichloromethane at 23℃; for 12h; Inert atmosphere;99%
2-(trifluoromethyl)phenol
444-30-4

2-(trifluoromethyl)phenol

ethyl chloromethyl ether
3188-13-4

ethyl chloromethyl ether

1-(ethoxymethoxy)-2-(trifluoromethyl)benzene
1391830-45-7

1-(ethoxymethoxy)-2-(trifluoromethyl)benzene

Conditions
ConditionsYield
Stage #1: 2-(trifluoromethyl)phenol With sodium hydride In tetrahydrofuran at 0 - 20℃; for 1h; Inert atmosphere; Schlenk technique;
Stage #2: ethyl chloromethyl ether In tetrahydrofuran at 20℃; for 12h; Inert atmosphere; Schlenk technique;
99%
6-hydroxy-2-bromo-benzothiazole
808755-67-1

6-hydroxy-2-bromo-benzothiazole

ethyl chloromethyl ether
3188-13-4

ethyl chloromethyl ether

2-bromo-6-(ethoxymethoxy)benzo[d]thiazole
1427773-37-2

2-bromo-6-(ethoxymethoxy)benzo[d]thiazole

Conditions
ConditionsYield
With caesium carbonate In N,N-dimethyl-formamide99%
2-bromoresorcinol
6751-75-3

2-bromoresorcinol

ethyl chloromethyl ether
3188-13-4

ethyl chloromethyl ether

2-bromo-1,3-bis(ethoxymethoxy)benzene
1610702-02-7

2-bromo-1,3-bis(ethoxymethoxy)benzene

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In dichloromethane at 0 - 20℃; Inert atmosphere;99%
3-hydroxy-2-naphthoic acid methyl ester
883-99-8

3-hydroxy-2-naphthoic acid methyl ester

ethyl chloromethyl ether
3188-13-4

ethyl chloromethyl ether

C15H16O4
1621132-93-1

C15H16O4

Conditions
ConditionsYield
Stage #1: 3-hydroxy-2-naphthoic acid methyl ester With sodium hydride
Stage #2: ethyl chloromethyl ether
99%
Stage #1: 3-hydroxy-2-naphthoic acid methyl ester With sodium hydride In tetrahydrofuran for 0.333333h; Cooling with ice;
Stage #2: ethyl chloromethyl ether In tetrahydrofuran at 20℃;
C13H10BrClO2
943920-03-4

C13H10BrClO2

ethyl chloromethyl ether
3188-13-4

ethyl chloromethyl ether

C16H16BrClO3

C16H16BrClO3

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In dichloromethane at 20℃;99%
2,5-dimethoxyphenol
18113-18-3

2,5-dimethoxyphenol

ethyl chloromethyl ether
3188-13-4

ethyl chloromethyl ether

2-(ethoxymethoxy)-1,4-dimethoxybenzene

2-(ethoxymethoxy)-1,4-dimethoxybenzene

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In chloroform at 60℃; for 20h;99%
2-hydroxynitrobenzene
88-75-5

2-hydroxynitrobenzene

ethyl chloromethyl ether
3188-13-4

ethyl chloromethyl ether

1-(ethoxymethoxy)-2-nitrobenzene

1-(ethoxymethoxy)-2-nitrobenzene

Conditions
ConditionsYield
Stage #1: 2-hydroxynitrobenzene With sodium hydride In tetrahydrofuran at 0℃; for 0.5h;
Stage #2: ethyl chloromethyl ether In tetrahydrofuran at 0℃; for 2h;
99%
methyl (E)-sinapate
42041-51-0

methyl (E)-sinapate

ethyl chloromethyl ether
3188-13-4

ethyl chloromethyl ether

(E)-methyl 3-(4-(ethoxymethoxy)-3,5-dimethoxyphenyl)acrylate

(E)-methyl 3-(4-(ethoxymethoxy)-3,5-dimethoxyphenyl)acrylate

Conditions
ConditionsYield
Stage #1: methyl (E)-sinapate With sodium hydride In tetrahydrofuran; mineral oil at 0℃; for 0.166667h; Inert atmosphere;
Stage #2: ethyl chloromethyl ether In tetrahydrofuran; mineral oil at 0 - 20℃; for 2h; Inert atmosphere;
99%
4-(6-hydroxyhexyloxy)benzoic acid
83883-25-4

4-(6-hydroxyhexyloxy)benzoic acid

ethyl chloromethyl ether
3188-13-4

ethyl chloromethyl ether

C16H24O5

C16H24O5

Conditions
ConditionsYield
With triethylamine In tetrahydrofuran at 0 - 25℃;99%
methyl (S)-2-(tert-butoxycarbonylamino)-3-(3,4-dihydroxyphenyl)propanoate
37169-36-1

methyl (S)-2-(tert-butoxycarbonylamino)-3-(3,4-dihydroxyphenyl)propanoate

ethyl chloromethyl ether
3188-13-4

ethyl chloromethyl ether

(S)-methyl 3-(3,4-bis(ethoxymethoxy)phenyl)-2-((tertbutoxycarbonyl)amino)propanoate

(S)-methyl 3-(3,4-bis(ethoxymethoxy)phenyl)-2-((tertbutoxycarbonyl)amino)propanoate

Conditions
ConditionsYield
Stage #1: methyl (S)-2-(tert-butoxycarbonylamino)-3-(3,4-dihydroxyphenyl)propanoate With N-ethyl-N,N-diisopropylamine In tetrahydrofuran at 20℃; for 0.166667h; Inert atmosphere;
Stage #2: ethyl chloromethyl ether at 0 - 40℃; for 15h; Inert atmosphere; Sealed tube;
99%
1-((2-(2-(pyrrolidin-1-yl)ethoxy)naphthalen-1-yl)methyl)naphthalen-2-ol

1-((2-(2-(pyrrolidin-1-yl)ethoxy)naphthalen-1-yl)methyl)naphthalen-2-ol

ethyl chloromethyl ether
3188-13-4

ethyl chloromethyl ether

1-(2-((1-((2-(ethoxymethoxy)naphthalen-1-yl)methyl)naphthalen-2-yl)oxy)ethyl)pyrrolidine

1-(2-((1-((2-(ethoxymethoxy)naphthalen-1-yl)methyl)naphthalen-2-yl)oxy)ethyl)pyrrolidine

Conditions
ConditionsYield
With dmap; N-ethyl-N,N-diisopropylamine In dichloromethane at 0 - 20℃; for 16h; Inert atmosphere;99%
4-hydroxy-benzaldehyde
123-08-0

4-hydroxy-benzaldehyde

ethyl chloromethyl ether
3188-13-4

ethyl chloromethyl ether

4-(ethyloxymethoxy)benzaldehyde
128837-26-3

4-(ethyloxymethoxy)benzaldehyde

Conditions
ConditionsYield
Stage #1: 4-hydroxy-benzaldehyde With potassium carbonate In acetone at 0℃; for 0.333333h;
Stage #2: ethyl chloromethyl ether With tetra-(n-butyl)ammonium iodide In acetone at 0 - 20℃; for 8h;
98%
With sodium hydroxide In dichloromethane; water for 16h; Substitution; Williamson reaction;96%
Stage #1: 4-hydroxy-benzaldehyde With triethylamine In acetone at 20℃; for 0.333333h;
Stage #2: ethyl chloromethyl ether With tetra-(n-butyl)ammonium iodide In acetone at 0 - 20℃; for 22h;
88%
vanillin
121-33-5

vanillin

ethyl chloromethyl ether
3188-13-4

ethyl chloromethyl ether

4-Ethoxymethoxy-3-methoxybenzaldehyde
128837-27-4

4-Ethoxymethoxy-3-methoxybenzaldehyde

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In dichloromethane at 0 - 20℃; for 19h; Inert atmosphere;98%
With potassium carbonate In acetone for 1h; Heating;3.5 g
With potassium carbonate In DMF (N,N-dimethyl-formamide) at 20℃; for 2h;
cyclohexenone
930-68-7

cyclohexenone

ethyl chloromethyl ether
3188-13-4

ethyl chloromethyl ether

1-ethoxymethyl-2-cyclohexen-1-ol

1-ethoxymethyl-2-cyclohexen-1-ol

Conditions
ConditionsYield
With lithium; 4,4'-di-tert-butylbiphenyl In tetrahydrofuran at 0℃; for 0.75h; other aldehydes and ketones;98%
With lithium; 4,4'-di-tert-butylbiphenyl In tetrahydrofuran at 0℃;98%
With 4,4'-di-tert-butylbiphenyl; lithium In tetrahydrofuran at 0℃;98%
ethyl (S)-3-hydroxybutyrate
56816-01-4

ethyl (S)-3-hydroxybutyrate

ethyl chloromethyl ether
3188-13-4

ethyl chloromethyl ether

(S)-ethyl 3-(ethoxymethoxy)butanoate
137645-28-4

(S)-ethyl 3-(ethoxymethoxy)butanoate

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In dichloromethane at 0 - 20℃; for 17h; Inert atmosphere;98%
90%

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