Sichuan Tongsheng is the most strongest manufacturer and exporter of amino acids and their derivatives in China, we have the best quality and price. Guarantee high quality, competive price and reliable service. We fully compliance with ISO9001:2008,
The area of Chengdu Baishixing is 35,000 square metre , the staff members are 88, our output value is over 120 millions per year. Baishiying cooporates with Life Science Academy of Wuhan University to develop amino acids series products.W
DayangChem exported this product to many countries and regions at best price. If you are looking for the material's manufacturer or supplier in China, DayangChem is your best choice. Pls contact with us freely for getting detailed product spe
Cas:328-38-1
Min.Order:1 Kilogram
FOB Price: $3.0
Type:Lab/Research institutions
inquiryWelcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our
Cas:328-38-1
Min.Order:1 Kilogram
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Type:Manufacturers
inquiryItems Standard Result Assay (Ursolic acid) 98%min 98.22% -----------------------------------------------------------------------------------------------------------
Cas:328-38-1
Min.Order:1 Gram
FOB Price: $100.0 / 500.0
Type:Trading Company
inquiryUnique advantages Guaranteed purity High quality & competitive price Quality control Fast feedback Prompt shipment Appearance:White crystalline powder Storage:Cool dry place Package:1kg/foill bag;25kg/drum Applic
Cas:328-38-1
Min.Order:1 Kilogram
Negotiable
Type:Trading Company
inquiryhe company has advanced technology, as well as a large number of excellent R & D team, to provide customers from the grams to one hundred kilograms and tons of high-quality products, competitive prices and quality se T rvice Appeara
The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi
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Cas:328-38-1
Min.Order:1 Gram
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Type:Manufacturers
inquiryOur main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block
Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.
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Cas:328-38-1
Min.Order:1 Kilogram
FOB Price: $9.0 / 99.0
Type:Trading Company
inquiryWITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et
Cas:328-38-1
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FOB Price: $139.0 / 210.0
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inquiryProduct Name: D-2-Amino-4-methylpentanoic acid Synonyms: (R)-(-)-LEUCINE;(R)-LEUCINE;(R)-2-AMINO-4-METHYLPENTANOIC ACID;(R)-2-AMINO-4-METHYLVALERIC ACID;d-leucin;Leucine, D-;D-LEU;D-LEUCINE CAS: 328-38-1 MF: C6H13NO2 MW: 131.17 EINECS: 206-327
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Min.Order:1 Gram
Negotiable
Type:Trading Company
inquiry1.Prompt Goods; 2.Flexible payment terms; 3.Documents & Certificate support. Name: D-Leucine Structure: Formula: C6H13NO2 Molecular Weight : 131.17 Synonyms: D-Leucine≥ 99.5% (anhydrous assay);(R)-(-)-LEUCINE;(R)-LEUCINE;(R)-2-AMINO-4-
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Min.Order:1 Kilogram
Negotiable
Type:Lab/Research institutions
inquiryWe are the manufacturers and suppliers of API in China, and warehouse in Germany and USA of California, which can quickly and safely deliver to your address 1.High quality and competitive price. 2.Free sample for your evaluation. 3.Promptly delivery
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Min.Order:10 Gram
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Type:Trading Company
inquiryOur company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At prese
Cas:328-38-1
Min.Order:1 Kilogram
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Type:Trading Company
inquiryQingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic intermediates, steroids, pharmaceutical
Cas:328-38-1
Min.Order:10 Gram
Negotiable
Type:Lab/Research institutions
inquiryHenan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod
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Min.Order:1 Kilogram
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Type:Trading Company
inquiryOverview of Our Factories Our Factories production lines Our Factories R&D ability Our Factories warehouse Our Factorie
Cas:328-38-1
Min.Order:1 Kilogram
FOB Price: $40.0 / 50.0
Type:Lab/Research institutions
inquiryAppearance:white crystals powder Storage:Room temperature Package:25kg/drum Application:Amino acid Transportation:Express/Sea/Air Port:Any port in china
Cas:328-38-1
Min.Order:25 Kilogram
Negotiable
Type:Lab/Research institutions
inquiryBest quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia
Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det
Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We
Company Introduction 1. Established in 2005, with two independent business divisions: Fine chemicals division; Pharmaceutical division. 2. Main product: Optical brightener Textile auxiliary Dye stuff Pigments
Cas:328-38-1
Min.Order:1 Gram
Negotiable
Type:Lab/Research institutions
inquiryJ&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia
A substitute for perfluorooctanoic acid, mainly used as a surfactant, dispersant, additive, etc Appearance:White solid or Colorless liquid Purity:99.3 % We will ship the goods in a timely manner as required We can provide relevant documents acc
N-(9-fluorenylmethoxycarbonyl)-D-leucine
(R)-leucine
Conditions | Yield |
---|---|
With piperidine In N,N-dimethyl-formamide at 20℃; | 100% |
(R)-N-benzylleucine
(R)-leucine
Conditions | Yield |
---|---|
With hydrogen; palladium on activated charcoal In acetic acid for 24h; | 98% |
(R)-2-azido-4-methylpentanoic acid
(R)-leucine
Conditions | Yield |
---|---|
With hydrogen; palladium on activated charcoal In water; acetic acid under 760 Torr; for 4h; | 92% |
D-α-Hydrazino-isocapronsaeure
(R)-leucine
Conditions | Yield |
---|---|
With hydrogen; platinum(IV) oxide | 91% |
(R)-2-Amino-4-methyl-pentanoic acid ((1S,2S)-2-hydroxy-1-methyl-2-phenyl-ethyl)-methyl-amide
A
(R)-leucine
B
pseudoephedrine
Conditions | Yield |
---|---|
With water for 10h; Heating; | A 86% B n/a |
(R)-2-Amino-4-methyl-pentanoic acid ((1S,2S)-2-hydroxy-1-methyl-2-phenyl-ethyl)-methyl-amide
(R)-leucine
Conditions | Yield |
---|---|
In water for 10h; Heating; other reagent; | 86% |
Conditions | Yield |
---|---|
With D-glucose; Bacillus subtilis glucose dehydrogenase; Symbiobacterium thermophilum meso-Diaminopimelate dehydrogenase W121L/H227I mutant; NADP; ammonium chloride In aq. buffer at 37℃; for 24h; pH=8.5; Kinetics; Reagent/catalyst; Enzymatic reaction; | 68% |
With D-Alanine; meso-diaminopimelate dehydrogenase; pyridoxal 5'-phosphate; alcohol dehydrogenases from Bacillus stearothermophilus; alcohol dehydrogenases from Thermoanaerobacter brockii; NADH In isopropyl alcohol at 35℃; for 12h; pH=8; Reagent/catalyst; Enzymatic reaction; enantioselective reaction; | 53.2% |
With meso-2,6-D-diaminopimelic acid dehydrogenase mutant BC621; ammonium chloride; NADPH In various solvent(s) for 24h; | |
With D-amino acid transaminase; D-Alanine; R-selective ω-transaminase from Arthrobacter sp; (3-hydroxy-5-hydroxymethyl)-2-methylisonicotinic acid 5-phosphate; isopropylamine In aq. phosphate buffer for 7h; pH=7; | n/a |
With D-Glucose; Bacillus megaterium glucose dehydrogenase; ammonia; Symbiobacterium thermophilum mesodiaminopimelate dehydrogenase Enzymatic reaction; | n/a |
Conditions | Yield |
---|---|
With zinc(II) perchlorate; (S)-15-amino-methyl-14-hydroxy-5,5-dimethyl-2,8-dithia<9>(2,5)pyridinophane In methanol for 24h; Ambient temperature; | 66% |
Conditions | Yield |
---|---|
With yeast; Sucrose | |
beim Durchgang durch den Organismus des Kaninchens; | |
With penicillium glaucum |
Conditions | Yield |
---|---|
With (-)-(R,R)-dibenzoyltartaric acid |
Conditions | Yield |
---|---|
With ethanol; brucine man filtriert das sich ausscheid.Brucinsalz des Formyl-d-leucins ab,zerlegt es durch Natronlauge u.verseift das erhalt.Formyl-d-leucin durch Kochen mit 10prozentig.Salzsaeure o.durch Schuetteln mit 30prozentig.Bromwasserstoffsaeure b.37grad; |
N-formyl-D-leucine
(R)-leucine
Conditions | Yield |
---|---|
Hydrolysis; |
N-chloroacetyl-D-leucine
(R)-leucine
Conditions | Yield |
---|---|
With hydrogenchloride |
Z-D-Leu-OH
(R)-leucine
Conditions | Yield |
---|---|
With hydrogenchloride; palladium Hydrogenation; |
N-acetyl-D-leucine
(R)-leucine
Conditions | Yield |
---|---|
In water at 37℃; for 0.166667h; Rate constant; D-aminocyclase from Alcaligenes denitrificans DA181, pH 7.8, bovine serum albumin; | |
With D-aminoacylase from Alcaligenes xylosoxydans Enzyme kinetics; Further Variations:; Reagents; Deacetylation; |
isobutyl triflate
trans-(2S,5S)-N--2,5-bis(methoxymethoxymethyl)pyrrolidine
A
(R)-leucine
B
L-leucine
Conditions | Yield |
---|---|
Yield given. Multistep reaction. Yields of byproduct given; |
glycyl-L-leucylglycylglycine
A
(R)-leucine
B
[(S)-2-(2-Amino-acetylamino)-4-methyl-pentanoylamino]-acetic acid
C
glycyl-D-leucylglycine
D
glycyl-D-leucylglycylglycine
E
cyclo(glycyl-L-leucyl)
F
cyclo-(glycyl-D-leucyl)
Conditions | Yield |
---|---|
In various solvent(s) at 148.5℃; Product distribution; Rate constant; rate of racemization was investigated during decomposition; |
Conditions | Yield |
---|---|
With (R)-<methyl>pyridine; copper(II) ion In various solvent(s) at 25℃; Rate constant; enantioselectivity of cleavage; other chiral ligands; |
(2R,2'R)-N-(2'-amino-4'-methylpentanoyl)bornane-10,2-sultam
(R)-leucine
Conditions | Yield |
---|---|
With lithium hydroxide; ion exchange 1.) THF; Yield given. Multistep reaction; | |
With lithium hydroxide; Amberlite IR-120 1) THF, room temperature, 2) H2O, room temperature, 15 h; Yield given. Multistep reaction; |
theonellamine B
A
N-methylalanine
B
L-valine
C
L-threonine
D
N-methyl-L-valine
E
(R)-leucine
F
3-amino propanoic acid
Conditions | Yield |
---|---|
With hydrogenchloride at 110℃; for 4h; |
theonellamine B
A
L-valine
B
N-methyl-L-valine
C
(R)-leucine
D
3-amino propanoic acid
Conditions | Yield |
---|---|
With hydrogenchloride at 110℃; for 40h; Further byproducts given; |
Conditions | Yield |
---|---|
With hydrogen; Pd-BaSO4 In ethanol under 760 Torr; Ambient temperature; Yield given. Yields of byproduct given; |
Conditions | Yield |
---|---|
With triphenyl phosphite; oxygen In dichloromethane Product distribution; Ambient temperature; configuration; |
L-leucine (phenylmethyl)ester
A
(R)-leucine
B
L-leucine
C
L-Leucine benzyl ester
D
D-leucine benzyl ester
Conditions | Yield |
---|---|
With sodium bicarbonate buffer; subtilisin 8350 at 35℃; for 1h; Product distribution; var. DL-amino acid esters; |
9-fluorenylmethyloxycarbonyl-L-leucine anhydride
A
(R)-leucine
B
L-leucine
Conditions | Yield |
---|---|
With dmap; p-hydroxymethylphenoxyacetyl-polydimethylacrylamide resin; trifluoroacetic acid Product distribution; racemisation in dependence on sequence of addition of reagents; 1) dimethylacetamide, 3 h; |
N-carbamyl-D-leucine
(R)-leucine
Conditions | Yield |
---|---|
With potassium phosphate buffer; Pseudomonas sp. AJ-11220 In various solvent(s) at 30℃; for 2h; | |
With hydrogenchloride; sodium nitrite at 0℃; | |
With potassium phosphate buffer; Pseudomonas sp. AJ-11220 In various solvent(s) at 30℃; for 2h; pH 7.5; enzymatic reaction; |
5-isobutyl-imidazolidine-2,4-dione
(R)-leucine
Conditions | Yield |
---|---|
at 37℃; Pseudomonas Sp.; |
Conditions | Yield |
---|---|
With hydrogenchloride 1.) THF, from -78 to -40 degC; 2.) reflux; Yield given. Multistep reaction; |
methanol
(R)-leucine
(R)-leucine methyl ester hydrochloride
Conditions | Yield |
---|---|
With sulfuryl dichloride at 0 - 20℃; for 16h; Inert atmosphere; | 100% |
With thionyl chloride at 20℃; | 99% |
With thionyl chloride for 12h; Ambient temperature; | 94% |
Conditions | Yield |
---|---|
With sodium hydroxide In water at 0 - 20℃; | 100% |
With sodium hydroxide In water at 20℃; for 2h; | 90% |
With sodium hydrogencarbonate | 87% |
Stage #1: (R)-leucine With sodium hydroxide In water at 0℃; Cooling with ice; Stage #2: benzyl chloroformate In 1,4-dioxane; water at 20℃; | |
With sodium hydroxide In 1,4-dioxane at 0 - 20℃; |
Conditions | Yield |
---|---|
With thionyl chloride for 4h; Reflux; | 100% |
With hydrogenchloride Heating; | 87% |
phthalic anhydride
(R)-leucine
(R)-2-(1,3-dioxoisoindolin-2-yl)-4-methylpentanoic acid
Conditions | Yield |
---|---|
for 0.0611111h; microwave irradiation; | 98% |
at 150℃; |
(R)-leucine
N-1-naphthalenesulfonyl-D-leucine
Conditions | Yield |
---|---|
With hydrogenchloride In 1,4-dioxane | 98% |
(R)-leucine
1-Naphthalenesulfonyl chloride
N-1-naphthalenesulfonyl-D-leucine
Conditions | Yield |
---|---|
With sodium hydroxide In 1,4-dioxane at 0 - 20℃; for 4h; pH=9 - 10; | 98% |
Conditions | Yield |
---|---|
With sodium hydroxide In 1,4-dioxane at 0 - 20℃; Inert atmosphere; | 97% |
Stage #1: (R)-leucine With sodium hydroxide In tetrahydrofuran; water for 0.25h; Inert atmosphere; Cooling with ice; Stage #2: di-tert-butyl dicarbonate In tetrahydrofuran; water at 20℃; for 24h; pH=Ca. 10.5; Inert atmosphere; Cooling with ice; | 97.2% |
Stage #1: (R)-leucine With potassium carbonate In acetone at 20℃; for 0.0833333h; Stage #2: di-tert-butyl dicarbonate In acetone | 95% |
Conditions | Yield |
---|---|
In N,N-dimethyl-formamide Microwave irradiation; | 97% |
N-succinimidyl 3,5-dichlorobenzoate
(R)-leucine
Conditions | Yield |
---|---|
With sodium hydrogencarbonate In tetrahydrofuran; water at 20℃; for 18h; | 97% |
(R)-leucine
4-bromobenzenesulfonyl chloride
N-p-bromo-benzenesulfonyl-D-leucine
Conditions | Yield |
---|---|
With hydrogenchloride In 1,4-dioxane | 96.4% |
(R)-leucine
4-bromobenzenesulfonyl chloride
N-p-bromobenzenesulfonyl-D-leucine
Conditions | Yield |
---|---|
With sodium hydroxide In 1,4-dioxane at 0 - 20℃; for 4h; pH=9 - 10; | 96.4% |
Conditions | Yield |
---|---|
With toluene-4-sulfonic acid In benzene for 16h; Heating; | 95% |
Conditions | Yield |
---|---|
With potassium phosphate In tetrahydrofuran for 24h; Inert atmosphere; | 94% |
With sodium hydroxide for 2.5h; Ambient temperature; |
Conditions | Yield |
---|---|
With sodium hydroxide In 1,4-dioxane at 0 - 20℃; for 4h; pH=9 - 10; | 94% |
With sodium carbonate In water |
(R)-leucine
di(μ-chloro)bis[1-(phenylazo)phenyl-C(2)N]dipalladium(II)
Conditions | Yield |
---|---|
With NaOMe In methanol N2-atmosphere; dropwise addn. of 1 equiv. NaOMe to aminoacid, gentle heating to dissoln., addn. of stoich. amt. Pd-complex, stirring for 15 h; solvent removal (vac.), dissoln. in CH2Cl2, centrifugation, solvent removal (vac.); elem. anal.; | 94% |
Conditions | Yield |
---|---|
With hydrogenchloride In 1,4-dioxane | 94% |
(R)-leucine
(R)-2-hydroxy-4-methylpentanoic acid
Conditions | Yield |
---|---|
With sulfuric acid; sodium nitrite In water at 5 - 20℃; | 93.8% |
With sulfuric acid; sodium nitrite at 0℃; | 79% |
With sulfuric acid; water; sodium nitrite | 76% |
Conditions | Yield |
---|---|
With thionyl chloride for 6h; Ambient temperature; | 91% |
With chlorosulfonic acid at 20℃; for 2h; | 80% |
With hydrogenchloride |
(R)-leucine
N-t-butoxycarbonyl-(R)-proline N-hydroxysuccuinimide ester
N-(tert-butoxycarbonyl)-(R)-prolyl-(R)-leucine
Conditions | Yield |
---|---|
With sodium hydroxide; potassium hydrogencarbonate In 1,4-dioxane 1.) 0 deg C, overnight; 2.) r.t., 24 h; | 90% |
Conditions | Yield |
---|---|
Stage #1: (R)-leucine; acetic anhydride With sodium hydroxide In water at 5 - 15℃; for 4 - 5h; Stage #2: With hydrogenchloride In water at 5 - 15℃; for 2.5h; | 89% |
Stage #1: (R)-leucine; acetic anhydride With sodium hydroxide In water at 5 - 15℃; for 2h; pH=8-9; Inert atmosphere; Large scale; Stage #2: With hydrogenchloride In water at 5 - 15℃; for 2.5h; Inert atmosphere; Large scale; | 89% |
With sodium hydroxide In water at 20℃; pH=14; | |
In tetrahydrofuran; water |
Conditions | Yield |
---|---|
With sodium hydrogencarbonate In water; acetonitrile at 20℃; for 0.5h; pH=8.5; | 88.7% |
(R)-leucine
Conditions | Yield |
---|---|
Stage #1: (R)-leucine With dicyclohexyl-carbodiimide In dichloromethane for 0.333333h; Stage #2: N-((1S,2R,4aS,5R,8aS)-2-hydroxy-1,4a-dimethyl-6-methylene-5-((E)-2-(2-oxo-2,5-dihydrofuran-3-yl)ethenyl)decahydronaphthalen-1-yl)formamide With dmap In dichloromethane at 20℃; for 2h; | 88% |
(R)-leucine
(1R,2S,5R)-menthyl chloroformate
N-[(-)-menthoxylcarbonyl]-D-leucine
Conditions | Yield |
---|---|
With sodium hydroxide In water at 0℃; for 0.5h; Schlenk technique; Inert atmosphere; | 87% |
(R)-leucine
(R)-2-bromo-4-methylpentanoic acid
Conditions | Yield |
---|---|
With hydrogen bromide; sodium nitrite In water at 0℃; for 2.5h; | 86% |
With hydrogen bromide; sodium nitrite In water at 0℃; for 2.5h; Inert atmosphere; | 85% |
With potassium bromide; sodium nitrite In water | 83% |
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