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SICHUAN TONGSHENG AMINOACID CO.LTD

Sichuan Tongsheng is the most strongest manufacturer and exporter of amino acids and their derivatives in China, we have the best quality and price. Guarantee high quality, competive price and reliable service. We fully compliance with ISO9001:2008,

D-Leucine

Cas:328-38-1

Min.Order:1 Gram

Negotiable

Type:Manufacturers

inquiry

Chengdu Baishixing Science and Technology Industry Co., Ltd.

The area of Chengdu Baishixing is 35,000 square metre , the staff members are 88, our output value is over 120 millions per year. Baishiying cooporates with Life Science Academy of Wuhan University to develop amino acids series products.W

D-Leucine

Cas:328-38-1

Min.Order:1 Kilogram

Negotiable

Type:Manufacturers

inquiry

Dayang Chem (Hangzhou) Co.,Ltd.

DayangChem exported this product to many countries and regions at best price. If you are looking for the material's manufacturer or supplier in China, DayangChem is your best choice. Pls contact with us freely for getting detailed product spe

D-Leucine Manufacturer/High quality/Best price/In stock

Cas:328-38-1

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality d-2-amino-4-methylpentanoic acid supplier in China

Cas:328-38-1

Min.Order:1 Kilogram

Negotiable

Type:Manufacturers

inquiry

Hangzhou Dingyan Chem Co., Ltd

Items Standard Result Assay (Ursolic acid) 98%min 98.22% -----------------------------------------------------------------------------------------------------------

High purity 328-38-1 D-Leucine

Cas:328-38-1

Min.Order:1 Gram

FOB Price: $100.0 / 500.0

Type:Trading Company

inquiry

Wuhan Fortuna Chemical Co.,Ltd

Unique advantages Guaranteed purity High quality & competitive price Quality control Fast feedback Prompt shipment Appearance:White crystalline powder Storage:Cool dry place Package:1kg/foill bag;25kg/drum Applic

Factory supply D-2-Amino-4-methylpentanoic acid Cas 328-38-1 with high quality and best price

Cas:328-38-1

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Henan Allgreen Chemical Co.,Ltd

he company has advanced technology, as well as a large number of excellent R & D team, to provide customers from the grams to one hundred kilograms and tons of high-quality products, competitive prices and quality se T rvice Appeara

D-Leucine

Cas:328-38-1

Min.Order:1 Kilogram

Negotiable

Type:Manufacturers

inquiry

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply D-Leucine

Cas:328-38-1

Min.Order:1

Negotiable

Type:Other

inquiry

Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

High Quality Food Grade D-Leucine 328-38-1 HACCP Manufacturer

Cas:328-38-1

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

inquiry

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

D-Leucine

Cas:328-38-1

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.

328-38-1

Cas:328-38-1

Min.Order:1 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

Our advantages: 1. All inquiries will be replied within 12 hours. 2. Dedication to quality, supply & service. 3. Strictly on selecting raw materials. 4. Reasonable & competitive price, fast lead time. 5. Sample is available for your eva

D-2-Amino-4-methylpentanoic acid

Cas:328-38-1

Min.Order:1 Kilogram

FOB Price: $9.0 / 99.0

Type:Trading Company

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Factory direct supply CAS 328-38-1 with best quality

Cas:328-38-1

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

inquiry

Henan Sinotech Import&Export Corporation

Product Name: D-2-Amino-4-methylpentanoic acid Synonyms: (R)-(-)-LEUCINE;(R)-LEUCINE;(R)-2-AMINO-4-METHYLPENTANOIC ACID;(R)-2-AMINO-4-METHYLVALERIC ACID;d-leucin;Leucine, D-;D-LEU;D-LEUCINE CAS: 328-38-1 MF: C6H13NO2 MW: 131.17 EINECS: 206-327

D-Leucine 328-38-1

Cas:328-38-1

Min.Order:5 Metric Ton

FOB Price: $1.0 / 2.0

Type:Other

inquiry

Hangzhou JINLAN Pharm-Drugs Technology Co., Ltd

We can provide GMP validation service that complies with SFDA, FDA, WHO and EU EMPA.Excellent registration team could help us easlily to register our products in different countries.If you and your customer are interested in some products or need CMO

D-leucine manufacturer/supplier

Cas:328-38-1

Min.Order:1 Gram

Negotiable

Type:Trading Company

inquiry

HANWAYS CHEMPHARM CO.,LIMITED

1.Prompt Goods; 2.Flexible payment terms; 3.Documents & Certificate support. Name: D-Leucine Structure: Formula: C6H13NO2 Molecular Weight : 131.17 Synonyms: D-Leucine≥ 99.5% (anhydrous assay);(R)-(-)-LEUCINE;(R)-LEUCINE;(R)-2-AMINO-4-

D-Leucine

Cas:328-38-1

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

D-Leucine 328-38-1

Cas:328-38-1

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Xi'an Faithful Biotech Co., Ltd.

We are the manufacturers and suppliers of API in China, and warehouse in Germany and USA of California, which can quickly and safely deliver to your address 1.High quality and competitive price. 2.Free sample for your evaluation. 3.Promptly delivery

Baoji Guokang Healthchem co.,ltd

Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At prese

D-2-Amino-4-methylpentanoic acid

Cas:328-38-1

Min.Order:1 Kilogram

FOB Price: $154.0 / 189.0

Type:Trading Company

inquiry

Qingdao Beluga Import and Export Co., LTD

Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic intermediates, steroids, pharmaceutical

D-2-Amino-4-methylpentanoic acid/328-38-1/D-Leucine Manufacturer/High quality

Cas:328-38-1

Min.Order:10 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

CAS NO.:328-38-1

Cas:328-38-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Mojin Biotechnology Co.,Ltd

Product quality: Our company have high quality product , and also the product we have good manufacture . First of all, this product is of fine quality. Every finish should be checked by quality inspection system.And every one should be also tried

High Quality D-Leucine Powder CAS 328-38-1

Cas:328-38-1

Min.Order:1 Kilogram

FOB Price: $250.0 / 260.0

Type:Trading Company

inquiry

Leader Biochemical Group

Overview of Our Factories Our Factories production lines Our Factories R&D ability Our Factories warehouse Our Factorie

China Biggest Factory & Manufacturer supply D-Leucine

Cas:328-38-1

Min.Order:1 Kilogram

FOB Price: $40.0 / 50.0

Type:Lab/Research institutions

inquiry

Hangzhou Sartort Biopharma Co., Ltd

Appearance:white crystals powder Storage:Room temperature Package:25kg/drum Application:Amino acid Transportation:Express/Sea/Air Port:Any port in china

High Purity In Stock D-Leucine H-D-Leu-OH Leucine

Cas:328-38-1

Min.Order:25 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Xiamen Hisunny Chemical Co.,Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia

D-Leucine

Cas:328-38-1

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

D-Leucine

Cas:328-38-1

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

D-Leucine

Cas:328-38-1

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

inquiry

Afine Chemicals Limited

Company Introduction 1. Established in 2005, with two independent business divisions: Fine chemicals division; Pharmaceutical division. 2. Main product: Optical brightener Textile auxiliary Dye stuff Pigments

(2S)-2-AMINO-4-METHYL-PENTANOIC ACID

Cas:328-38-1

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

D-Leucine

Cas:328-38-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

SHANGHAI T&W PHARMACEUTICAL CO., LTD.

A substitute for perfluorooctanoic acid, mainly used as a surfactant, dispersant, additive, etc Appearance:White solid or Colorless liquid Purity:99.3 % We will ship the goods in a timely manner as required We can provide relevant documents acc

H-D-Leu-OH

Cas:328-38-1

Min.Order:4 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Synthetic route

N-(9-fluorenylmethoxycarbonyl)-D-leucine
35661-60-0, 126727-03-5, 114360-54-2

N-(9-fluorenylmethoxycarbonyl)-D-leucine

(R)-leucine
328-38-1

(R)-leucine

Conditions
ConditionsYield
With piperidine In N,N-dimethyl-formamide at 20℃;100%
(R)-N-benzylleucine
89384-51-0

(R)-N-benzylleucine

(R)-leucine
328-38-1

(R)-leucine

Conditions
ConditionsYield
With hydrogen; palladium on activated charcoal In acetic acid for 24h;98%
(R)-2-azido-4-methylpentanoic acid
126191-08-0

(R)-2-azido-4-methylpentanoic acid

(R)-leucine
328-38-1

(R)-leucine

Conditions
ConditionsYield
With hydrogen; palladium on activated charcoal In water; acetic acid under 760 Torr; for 4h;92%
D-α-Hydrazino-isocapronsaeure
24292-07-7

D-α-Hydrazino-isocapronsaeure

(R)-leucine
328-38-1

(R)-leucine

Conditions
ConditionsYield
With hydrogen; platinum(IV) oxide91%
(R)-2-Amino-4-methyl-pentanoic acid ((1S,2S)-2-hydroxy-1-methyl-2-phenyl-ethyl)-methyl-amide
170642-24-7

(R)-2-Amino-4-methyl-pentanoic acid ((1S,2S)-2-hydroxy-1-methyl-2-phenyl-ethyl)-methyl-amide

A

(R)-leucine
328-38-1

(R)-leucine

B

pseudoephedrine
90-82-4

pseudoephedrine

Conditions
ConditionsYield
With water for 10h; Heating;A 86%
B n/a
(R)-2-Amino-4-methyl-pentanoic acid ((1S,2S)-2-hydroxy-1-methyl-2-phenyl-ethyl)-methyl-amide
170642-24-7

(R)-2-Amino-4-methyl-pentanoic acid ((1S,2S)-2-hydroxy-1-methyl-2-phenyl-ethyl)-methyl-amide

(R)-leucine
328-38-1

(R)-leucine

Conditions
ConditionsYield
In water for 10h; Heating; other reagent;86%
4-methyl-2-oxopentanoic acid
816-66-0

4-methyl-2-oxopentanoic acid

(R)-leucine
328-38-1

(R)-leucine

Conditions
ConditionsYield
With D-glucose; Bacillus subtilis glucose dehydrogenase; Symbiobacterium thermophilum meso-Diaminopimelate dehydrogenase W121L/H227I mutant; NADP; ammonium chloride In aq. buffer at 37℃; for 24h; pH=8.5; Kinetics; Reagent/catalyst; Enzymatic reaction;68%
With D-Alanine; meso-diaminopimelate dehydrogenase; pyridoxal 5'-phosphate; alcohol dehydrogenases from Bacillus stearothermophilus; alcohol dehydrogenases from Thermoanaerobacter brockii; NADH In isopropyl alcohol at 35℃; for 12h; pH=8; Reagent/catalyst; Enzymatic reaction; enantioselective reaction;53.2%
With meso-2,6-D-diaminopimelic acid dehydrogenase mutant BC621; ammonium chloride; NADPH In various solvent(s) for 24h;
With D-amino acid transaminase; D-Alanine; R-selective ω-transaminase from Arthrobacter sp; (3-hydroxy-5-hydroxymethyl)-2-methylisonicotinic acid 5-phosphate; isopropylamine In aq. phosphate buffer for 7h; pH=7;n/a
With D-Glucose; Bacillus megaterium glucose dehydrogenase; ammonia; Symbiobacterium thermophilum mesodiaminopimelate dehydrogenase Enzymatic reaction;n/a
sodium 4-methyl-2-oxovalerate
4502-00-5

sodium 4-methyl-2-oxovalerate

(R)-leucine
328-38-1

(R)-leucine

Conditions
ConditionsYield
With zinc(II) perchlorate; (S)-15-amino-methyl-14-hydroxy-5,5-dimethyl-2,8-dithia<9>(2,5)pyridinophane In methanol for 24h; Ambient temperature;66%
LEUCINE
328-39-2

LEUCINE

(R)-leucine
328-38-1

(R)-leucine

Conditions
ConditionsYield
With yeast; Sucrose
beim Durchgang durch den Organismus des Kaninchens;
With penicillium glaucum
DL-leucine ethyl ester
2899-43-6

DL-leucine ethyl ester

(R)-leucine
328-38-1

(R)-leucine

Conditions
ConditionsYield
With (-)-(R,R)-dibenzoyltartaric acid
N-formyl-valine
5338-45-4

N-formyl-valine

(R)-leucine
328-38-1

(R)-leucine

Conditions
ConditionsYield
With ethanol; brucine man filtriert das sich ausscheid.Brucinsalz des Formyl-d-leucins ab,zerlegt es durch Natronlauge u.verseift das erhalt.Formyl-d-leucin durch Kochen mit 10prozentig.Salzsaeure o.durch Schuetteln mit 30prozentig.Bromwasserstoffsaeure b.37grad;
Conditions
ConditionsYield
Hydrolysis;
N-chloroacetyl-D-leucine
64830-83-7

N-chloroacetyl-D-leucine

(R)-leucine
328-38-1

(R)-leucine

Conditions
ConditionsYield
With hydrogenchloride
Z-D-Leu-OH
28862-79-5

Z-D-Leu-OH

(R)-leucine
328-38-1

(R)-leucine

Conditions
ConditionsYield
With hydrogenchloride; palladium Hydrogenation;
LEUCINE
328-39-2

LEUCINE

A

(R)-leucine
328-38-1

(R)-leucine

B

L-leucine
61-90-5

L-leucine

N-acetyl-D-leucine
19764-30-8

N-acetyl-D-leucine

(R)-leucine
328-38-1

(R)-leucine

Conditions
ConditionsYield
In water at 37℃; for 0.166667h; Rate constant; D-aminocyclase from Alcaligenes denitrificans DA181, pH 7.8, bovine serum albumin;
With D-aminoacylase from Alcaligenes xylosoxydans Enzyme kinetics; Further Variations:; Reagents; Deacetylation;
isobutyl triflate
60306-25-4

isobutyl triflate

trans-(2S,5S)-N--2,5-bis(methoxymethoxymethyl)pyrrolidine
108437-90-7

trans-(2S,5S)-N--2,5-bis(methoxymethoxymethyl)pyrrolidine

A

(R)-leucine
328-38-1

(R)-leucine

B

L-leucine
61-90-5

L-leucine

Conditions
ConditionsYield
Yield given. Multistep reaction. Yields of byproduct given;
glycyl-L-leucylglycylglycine
7325-21-5

glycyl-L-leucylglycylglycine

A

(R)-leucine
328-38-1

(R)-leucine

B

[(S)-2-(2-Amino-acetylamino)-4-methyl-pentanoylamino]-acetic acid
2576-67-2

[(S)-2-(2-Amino-acetylamino)-4-methyl-pentanoylamino]-acetic acid

C

glycyl-D-leucylglycine
131830-34-7

glycyl-D-leucylglycine

D

glycyl-D-leucylglycylglycine
117760-61-9

glycyl-D-leucylglycylglycine

E

cyclo(glycyl-L-leucyl)
5815-67-8, 5845-67-0, 108315-75-9

cyclo(glycyl-L-leucyl)

F

cyclo-(glycyl-D-leucyl)
108315-75-9

cyclo-(glycyl-D-leucyl)

Conditions
ConditionsYield
In various solvent(s) at 148.5℃; Product distribution; Rate constant; rate of racemization was investigated during decomposition;
Leucine p-nitrophenyl ester
17663-34-2, 66575-12-0

Leucine p-nitrophenyl ester

A

(R)-leucine
328-38-1

(R)-leucine

B

L-leucine
61-90-5

L-leucine

Conditions
ConditionsYield
With (R)-<methyl>pyridine; copper(II) ion In various solvent(s) at 25℃; Rate constant; enantioselectivity of cleavage; other chiral ligands;
(2R,2'R)-N-(2'-amino-4'-methylpentanoyl)bornane-10,2-sultam
129568-83-8

(2R,2'R)-N-(2'-amino-4'-methylpentanoyl)bornane-10,2-sultam

(R)-leucine
328-38-1

(R)-leucine

Conditions
ConditionsYield
With lithium hydroxide; ion exchange 1.) THF; Yield given. Multistep reaction;
With lithium hydroxide; Amberlite IR-120 1) THF, room temperature, 2) H2O, room temperature, 15 h; Yield given. Multistep reaction;
theonellamine B
105091-14-3, 119816-11-4

theonellamine B

A

N-methylalanine
3913-67-5

N-methylalanine

B

L-valine
72-18-4

L-valine

C

L-threonine
72-19-5

L-threonine

D

N-methyl-L-valine
2480-23-1

N-methyl-L-valine

E

(R)-leucine
328-38-1

(R)-leucine

F

3-amino propanoic acid
107-95-9

3-amino propanoic acid

Conditions
ConditionsYield
With hydrogenchloride at 110℃; for 4h;
theonellamine B
105091-14-3, 119816-11-4

theonellamine B

A

L-valine
72-18-4

L-valine

B

N-methyl-L-valine
2480-23-1

N-methyl-L-valine

C

(R)-leucine
328-38-1

(R)-leucine

D

3-amino propanoic acid
107-95-9

3-amino propanoic acid

Conditions
ConditionsYield
With hydrogenchloride at 110℃; for 40h; Further byproducts given;
(R)-2-Azido-4-methyl-pentanoic acid benzyl ester

(R)-2-Azido-4-methyl-pentanoic acid benzyl ester

A

(R)-leucine
328-38-1

(R)-leucine

B

L-leucine
61-90-5

L-leucine

Conditions
ConditionsYield
With hydrogen; Pd-BaSO4 In ethanol under 760 Torr; Ambient temperature; Yield given. Yields of byproduct given;
ulithiacyclamide A
74847-09-9

ulithiacyclamide A

A

L-threonine
72-19-5

L-threonine

B

(R)-leucine
328-38-1

(R)-leucine

C

L-cystine
56-89-3

L-cystine

Conditions
ConditionsYield
With triphenyl phosphite; oxygen In dichloromethane Product distribution; Ambient temperature; configuration;
L-leucine (phenylmethyl)ester
80089-22-1

L-leucine (phenylmethyl)ester

A

(R)-leucine
328-38-1

(R)-leucine

B

L-leucine
61-90-5

L-leucine

C

L-Leucine benzyl ester
1738-69-8

L-Leucine benzyl ester

D

D-leucine benzyl ester
46741-65-5

D-leucine benzyl ester

Conditions
ConditionsYield
With sodium bicarbonate buffer; subtilisin 8350 at 35℃; for 1h; Product distribution; var. DL-amino acid esters;
9-fluorenylmethyloxycarbonyl-L-leucine anhydride
70626-37-8

9-fluorenylmethyloxycarbonyl-L-leucine anhydride

A

(R)-leucine
328-38-1

(R)-leucine

B

L-leucine
61-90-5

L-leucine

Conditions
ConditionsYield
With dmap; p-hydroxymethylphenoxyacetyl-polydimethylacrylamide resin; trifluoroacetic acid Product distribution; racemisation in dependence on sequence of addition of reagents; 1) dimethylacetamide, 3 h;
N-carbamyl-D-leucine
54896-73-0

N-carbamyl-D-leucine

(R)-leucine
328-38-1

(R)-leucine

Conditions
ConditionsYield
With potassium phosphate buffer; Pseudomonas sp. AJ-11220 In various solvent(s) at 30℃; for 2h;
With hydrogenchloride; sodium nitrite at 0℃;
With potassium phosphate buffer; Pseudomonas sp. AJ-11220 In various solvent(s) at 30℃; for 2h; pH 7.5; enzymatic reaction;
5-isobutyl-imidazolidine-2,4-dione
67337-73-9

5-isobutyl-imidazolidine-2,4-dione

(R)-leucine
328-38-1

(R)-leucine

Conditions
ConditionsYield
at 37℃; Pseudomonas Sp.;
diethylaluminium cyanide
5804-85-3

diethylaluminium cyanide

2-Methoxy-naphthalene-1-sulfinic acid [3-methyl-but-(E)-ylidene]-amide

2-Methoxy-naphthalene-1-sulfinic acid [3-methyl-but-(E)-ylidene]-amide

(R)-leucine
328-38-1

(R)-leucine

Conditions
ConditionsYield
With hydrogenchloride 1.) THF, from -78 to -40 degC; 2.) reflux; Yield given. Multistep reaction;
methanol
67-56-1

methanol

(R)-leucine
328-38-1

(R)-leucine

(R)-leucine methyl ester hydrochloride
5845-53-4, 6322-53-8, 7517-19-3

(R)-leucine methyl ester hydrochloride

Conditions
ConditionsYield
With sulfuryl dichloride at 0 - 20℃; for 16h; Inert atmosphere;100%
With thionyl chloride at 20℃;99%
With thionyl chloride for 12h; Ambient temperature;94%
(R)-leucine
328-38-1

(R)-leucine

benzyl chloroformate
501-53-1

benzyl chloroformate

Z-D-Leu-OH
28862-79-5

Z-D-Leu-OH

Conditions
ConditionsYield
With sodium hydroxide In water at 0 - 20℃;100%
With sodium hydroxide In water at 20℃; for 2h;90%
With sodium hydrogencarbonate87%
Stage #1: (R)-leucine With sodium hydroxide In water at 0℃; Cooling with ice;
Stage #2: benzyl chloroformate In 1,4-dioxane; water at 20℃;
With sodium hydroxide In 1,4-dioxane at 0 - 20℃;
ethanol
64-17-5

ethanol

(R)-leucine
328-38-1

(R)-leucine

D-(-)-leucine ethyl ester hydrochloride
73913-65-2

D-(-)-leucine ethyl ester hydrochloride

Conditions
ConditionsYield
With thionyl chloride for 4h; Reflux;100%
With hydrogenchloride Heating;87%
phthalic anhydride
85-44-9

phthalic anhydride

(R)-leucine
328-38-1

(R)-leucine

(R)-2-(1,3-dioxoisoindolin-2-yl)-4-methylpentanoic acid
29588-87-2

(R)-2-(1,3-dioxoisoindolin-2-yl)-4-methylpentanoic acid

Conditions
ConditionsYield
for 0.0611111h; microwave irradiation;98%
at 150℃;
(R)-leucine
328-38-1

(R)-leucine

N-1-naphthalenesulfonyl-D-leucine
68305-80-6

N-1-naphthalenesulfonyl-D-leucine

Conditions
ConditionsYield
With hydrogenchloride In 1,4-dioxane98%
(R)-leucine
328-38-1

(R)-leucine

1-Naphthalenesulfonyl chloride
85-46-1

1-Naphthalenesulfonyl chloride

N-1-naphthalenesulfonyl-D-leucine
202326-38-3

N-1-naphthalenesulfonyl-D-leucine

Conditions
ConditionsYield
With sodium hydroxide In 1,4-dioxane at 0 - 20℃; for 4h; pH=9 - 10;98%
(R)-leucine
328-38-1

(R)-leucine

di-tert-butyl dicarbonate
24424-99-5

di-tert-butyl dicarbonate

N-Boc-D-Leu
16937-99-8

N-Boc-D-Leu

Conditions
ConditionsYield
With sodium hydroxide In 1,4-dioxane at 0 - 20℃; Inert atmosphere;97%
Stage #1: (R)-leucine With sodium hydroxide In tetrahydrofuran; water for 0.25h; Inert atmosphere; Cooling with ice;
Stage #2: di-tert-butyl dicarbonate In tetrahydrofuran; water at 20℃; for 24h; pH=Ca. 10.5; Inert atmosphere; Cooling with ice;
97.2%
Stage #1: (R)-leucine With potassium carbonate In acetone at 20℃; for 0.0833333h;
Stage #2: di-tert-butyl dicarbonate In acetone
95%
(R)-leucine
328-38-1

(R)-leucine

tetrachlorophthalic anhydride
117-08-8

tetrachlorophthalic anhydride

TCP-D-Leu-OH

TCP-D-Leu-OH

Conditions
ConditionsYield
In N,N-dimethyl-formamide Microwave irradiation;97%
N-succinimidyl 3,5-dichlorobenzoate
143558-02-5

N-succinimidyl 3,5-dichlorobenzoate

(R)-leucine
328-38-1

(R)-leucine

(R)-N-(3,5-dichlorobenzoyl)leucine

(R)-N-(3,5-dichlorobenzoyl)leucine

Conditions
ConditionsYield
With sodium hydrogencarbonate In tetrahydrofuran; water at 20℃; for 18h;97%
(R)-leucine
328-38-1

(R)-leucine

4-bromobenzenesulfonyl chloride
98-58-8

4-bromobenzenesulfonyl chloride

N-p-bromo-benzenesulfonyl-D-leucine
68305-78-2

N-p-bromo-benzenesulfonyl-D-leucine

Conditions
ConditionsYield
With hydrogenchloride In 1,4-dioxane96.4%
(R)-leucine
328-38-1

(R)-leucine

4-bromobenzenesulfonyl chloride
98-58-8

4-bromobenzenesulfonyl chloride

N-p-bromobenzenesulfonyl-D-leucine
1308991-43-6

N-p-bromobenzenesulfonyl-D-leucine

Conditions
ConditionsYield
With sodium hydroxide In 1,4-dioxane at 0 - 20℃; for 4h; pH=9 - 10;96.4%
(R)-leucine
328-38-1

(R)-leucine

benzyl alcohol
100-51-6

benzyl alcohol

D-leucine benzyl ester
46741-65-5

D-leucine benzyl ester

Conditions
ConditionsYield
With toluene-4-sulfonic acid In benzene for 16h; Heating;95%
(R)-leucine
328-38-1

(R)-leucine

cyclohexanylcarbonyl chloride
2719-27-9

cyclohexanylcarbonyl chloride

(R)-2-(cyclohexanecarboxamido)-4-methylpentanoic acid

(R)-2-(cyclohexanecarboxamido)-4-methylpentanoic acid

Conditions
ConditionsYield
With potassium phosphate In tetrahydrofuran for 24h; Inert atmosphere;94%
With sodium hydroxide for 2.5h; Ambient temperature;
(R)-leucine
328-38-1

(R)-leucine

4-Fluorobenzenesulfonyl chloride
349-88-2

4-Fluorobenzenesulfonyl chloride

N-p-fluorobenzenesulfonyl-D-leucine

N-p-fluorobenzenesulfonyl-D-leucine

Conditions
ConditionsYield
With sodium hydroxide In 1,4-dioxane at 0 - 20℃; for 4h; pH=9 - 10;94%
With sodium carbonate In water
(R)-leucine
328-38-1

(R)-leucine

di(μ-chloro)bis[1-(phenylazo)phenyl-C(2)N]dipalladium(II)
14873-53-1

di(μ-chloro)bis[1-(phenylazo)phenyl-C(2)N]dipalladium(II)

Pd(C6H4NNC6H5)(NH2CH(CH2CH(CH3)2)CO2)

Pd(C6H4NNC6H5)(NH2CH(CH2CH(CH3)2)CO2)

Conditions
ConditionsYield
With NaOMe In methanol N2-atmosphere; dropwise addn. of 1 equiv. NaOMe to aminoacid, gentle heating to dissoln., addn. of stoich. amt. Pd-complex, stirring for 15 h; solvent removal (vac.), dissoln. in CH2Cl2, centrifugation, solvent removal (vac.); elem. anal.;94%
(R)-leucine
328-38-1

(R)-leucine

4-Fluorobenzenesulfonyl chloride
349-88-2

4-Fluorobenzenesulfonyl chloride

N-p-fluoro-benzenesulfonyl-D-leucine

N-p-fluoro-benzenesulfonyl-D-leucine

Conditions
ConditionsYield
With hydrogenchloride In 1,4-dioxane94%
(R)-leucine
328-38-1

(R)-leucine

(R)-2-hydroxy-4-methylpentanoic acid
20312-37-2

(R)-2-hydroxy-4-methylpentanoic acid

Conditions
ConditionsYield
With sulfuric acid; sodium nitrite In water at 5 - 20℃;93.8%
With sulfuric acid; sodium nitrite at 0℃;79%
With sulfuric acid; water; sodium nitrite76%
methanol
67-56-1

methanol

(R)-leucine
328-38-1

(R)-leucine

D-leucine methyl ester
23032-21-5

D-leucine methyl ester

Conditions
ConditionsYield
With thionyl chloride for 6h; Ambient temperature;91%
With chlorosulfonic acid at 20℃; for 2h;80%
With hydrogenchloride
(R)-leucine
328-38-1

(R)-leucine

N-t-butoxycarbonyl-(R)-proline N-hydroxysuccuinimide ester
102185-34-2

N-t-butoxycarbonyl-(R)-proline N-hydroxysuccuinimide ester

N-(tert-butoxycarbonyl)-(R)-prolyl-(R)-leucine
91711-95-4

N-(tert-butoxycarbonyl)-(R)-prolyl-(R)-leucine

Conditions
ConditionsYield
With sodium hydroxide; potassium hydrogencarbonate In 1,4-dioxane 1.) 0 deg C, overnight; 2.) r.t., 24 h;90%
(R)-leucine
328-38-1

(R)-leucine

acetic anhydride
108-24-7

acetic anhydride

N-acetyl-D-leucine
19764-30-8

N-acetyl-D-leucine

Conditions
ConditionsYield
Stage #1: (R)-leucine; acetic anhydride With sodium hydroxide In water at 5 - 15℃; for 4 - 5h;
Stage #2: With hydrogenchloride In water at 5 - 15℃; for 2.5h;
89%
Stage #1: (R)-leucine; acetic anhydride With sodium hydroxide In water at 5 - 15℃; for 2h; pH=8-9; Inert atmosphere; Large scale;
Stage #2: With hydrogenchloride In water at 5 - 15℃; for 2.5h; Inert atmosphere; Large scale;
89%
With sodium hydroxide In water at 20℃; pH=14;
In tetrahydrofuran; water
(R)-leucine
328-38-1

(R)-leucine

2,7-disulfo-9-fluorenylmethoxycarbonyl chloride

2,7-disulfo-9-fluorenylmethoxycarbonyl chloride

C21H21NO10S2(2-)*2Na(1+)

C21H21NO10S2(2-)*2Na(1+)

Conditions
ConditionsYield
With sodium hydrogencarbonate In water; acetonitrile at 20℃; for 0.5h; pH=8.5;88.7%
(R)-leucine
328-38-1

(R)-leucine

N-((1S,2R,4aS,5R,8aS)-2-hydroxy-1,4a-dimethyl-6-methylene-5-((E)-2-(2-oxo-2,5-dihydrofuran-3-yl)ethenyl)decahydronaphthalen-1-yl)formamide

N-((1S,2R,4aS,5R,8aS)-2-hydroxy-1,4a-dimethyl-6-methylene-5-((E)-2-(2-oxo-2,5-dihydrofuran-3-yl)ethenyl)decahydronaphthalen-1-yl)formamide

(S)-(1S,2R,4aS,5R,8aS)-1-formamido-1,4a-dimethyl-6-methylene-5-((E)-2-(2-oxo-2,5-dihydrofuran-3-yl)ethenyl)decahydronaphthalen-2-yl 2-amino-4-methylpentanoate

(S)-(1S,2R,4aS,5R,8aS)-1-formamido-1,4a-dimethyl-6-methylene-5-((E)-2-(2-oxo-2,5-dihydrofuran-3-yl)ethenyl)decahydronaphthalen-2-yl 2-amino-4-methylpentanoate

Conditions
ConditionsYield
Stage #1: (R)-leucine With dicyclohexyl-carbodiimide In dichloromethane for 0.333333h;
Stage #2: N-((1S,2R,4aS,5R,8aS)-2-hydroxy-1,4a-dimethyl-6-methylene-5-((E)-2-(2-oxo-2,5-dihydrofuran-3-yl)ethenyl)decahydronaphthalen-1-yl)formamide With dmap In dichloromethane at 20℃; for 2h;
88%
(R)-leucine
328-38-1

(R)-leucine

(1R,2S,5R)-menthyl chloroformate
14602-86-9

(1R,2S,5R)-menthyl chloroformate

N-[(-)-menthoxylcarbonyl]-D-leucine
1627153-13-2

N-[(-)-menthoxylcarbonyl]-D-leucine

Conditions
ConditionsYield
With sodium hydroxide In water at 0℃; for 0.5h; Schlenk technique; Inert atmosphere;87%
(R)-leucine
328-38-1

(R)-leucine

(R)-2-bromo-4-methylpentanoic acid
42990-28-3

(R)-2-bromo-4-methylpentanoic acid

Conditions
ConditionsYield
With hydrogen bromide; sodium nitrite In water at 0℃; for 2.5h;86%
With hydrogen bromide; sodium nitrite In water at 0℃; for 2.5h; Inert atmosphere;85%
With potassium bromide; sodium nitrite In water83%

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