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Wuhan Fortuna Chemical Co.,Ltd

Good quality Sodium 3-N-Methyl-L-histidine CAS 368-16-1 with steady supply Company profile Wuhan Fortuna Chemical Co.,Ltd established in 2006, is a big integrative chemical enterprise being engaged in Pharmaceutical & its intermediates, Food

Good quality Sodium 3-N-Methyl-L-histidine CAS 368-16-1 with steady supply

Cas:368-16-1

Min.Order:1 Kilogram

FOB Price: $10.0

Type:Trading Company

inquiry

Dayang Chem (Hangzhou) Co.,Ltd.

DayangChem exported this product to many countries and regions at best price. If you are looking for the material's manufacturer or supplier in China, DayangChem is your best choice. Pls contact with us freely for getting detailed product spe

3-methyl-l-histidine n-hydrate

Cas:368-16-1

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

3-Methyl-L-histidine

Cas:368-16-1

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.O

TIANFU-CHEM 368-16-1 3-METHYL-L-HISTIDINE N-HYDRATE

Cas:368-16-1

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Pharmaceutical Grade CAS 368-16-1 with competitive price

Cas:368-16-1

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

inquiry

Shanghai Upbio Tech Co.,Ltd

1.In No Less 10 years exporting experience. you can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specializ

L-Histidine, 3-methyl-

Cas:368-16-1

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Qingdao Beluga Import and Export Co., LTD

3-METHYL-L-HISTIDINE CAS:368-16-1 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic inter

3-METHYL-L-HISTIDINE CAS:368-16-1

Cas:368-16-1

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

L-Histidine, 3-methyl-

Cas:368-16-1

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

HANGZHOU YUNUO CHEMICAL CO.,LTD

superior quality Appearance:powder Storage:Stored in cool, dry and ventilation place; Away from fire and heat Package:1kg/bag, 1kg/drum or 25kg/drum or as per your request. Application:3-N-Methyl-L-histidine is a potential compound to be used as a

L-Histidine, 3-methyl-

Cas:368-16-1

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

3-METHYL-L-HISTIDINE N-HYDRATE

Cas:368-16-1

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

L-Histidine, 3-methyl-

Cas:368-16-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

L-Histidine, 3-methyl-

Cas:368-16-1

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

Hangzhou Huarong Pharm Co., Ltd.

Hangzhou Huarong Pharm Co., Ltd.established since 2006 , has been actively developing specialty products for Finished Dosages, APIs, Intermediates, and Fine chemicals markets in North America, Europe, Korea, Japan, Mid-East and all over the World. Hu

3-Methyl-L-histidine

Cas:368-16-1

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Hunan chemfish Pharmaceutical co.,Ltd

Appearance:95%+ Package:R&D,Pilot run Transportation:per client require Port:Express ,Air, Sea

N-Methyl-L-histidine

Cas:368-16-1

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Suzhou Health Chemicals Co., Ltd.

High quality,stable supply chain.Appearance:white/off-white or light yellow Storage:Store in cool and dry place, keep away from strong light and heat. Package:aluminum bottle,glass bottle,PTFE bottle,cardboard drum Application:This product can be use

3-Methyl-L-histidine

Cas:368-16-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Henan Allgreen Chemical Co.,Ltd

high quality Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea

METHYL-L-HISTIDINE, 3-(RG)

Cas:368-16-1

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Antimex Chemical Limied

Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali

L-Histidine, 3-methyl-

Cas:368-16-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Ocean Chemical Co., Ltd.

★.Best quality according to requirement ★.Competitive price in China market ★.Mature Technical support ★.Professional logistic support

N-Methyl-L-histidine

Cas:368-16-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Wuhan Circle Star Chem-medical Technology co.,Ltd.

good quality, competitive price, thoughtful after sale serviceAppearance:white powder Storage:Keep it in dry,shady and cool place Package:25kg,50kg,180kg,200kg,250kg,1000kg,customization Application:Pharma;Industry;Agricultural;chemical reaserch Tran

3-METHYL-L-HISTIDINE

Cas:368-16-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Fandachem Co.,Ltd

L-Histidine, 3-methyl-Appearance:white crystalline powder Storage:Store in dry, dark and ventilated place Package:25KG drum Application:pharmaceutical intermediate Transportation:by air, by sea, by express

L-Histidine, 3-methyl-

Cas:368-16-1

Min.Order:0

Negotiable

Type:Other

inquiry

NANJING SUNNY PHARMATECH CO., LTD

We are professional supplier in China for this product, we are dedicated to providing customers with the best quality, price, and service. Please feel free to send us inquiries.Appearance:Please contact us for product details Package:As per shipment

3-Methyl-L-histidine

Cas:368-16-1

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Henan Kanbei Chemical Co.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

3-METHYL-L-HISTIDINE N-HYDRATE

Cas:368-16-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Yuanye Bio-Technology Co., Ltd.

good quality, competitive price, thoughtful after sale serviceAppearance:white powder Storage:Keep it in dry,shady and cool place Package:50mg Application:Pharma;Industry;Agricultural;chemical reaserch Transportation:by express or by sea Port:Any por

3-Methyl-L-histidine

Cas:368-16-1

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Hunan Russell Chemicals Technology Co.,Ltd

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:Foil bag; Drum; Plastic bottle Application:Pharma;Industry;Agricultural Transportation:by sea or air Port:any port in China

N-Methyl-L-histidine 368-16-1

Cas:368-16-1

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Shenzhen Foris Technology Co. LTD

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:Foil bag; Drum; Plastic bottle Application:Pharma;Industry;Agricultural Transportation:by sea or air Port:any port in China

N-Methyl-L-histidine 368-16-1

Cas:368-16-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

ZHEJIANG JIUZHOU CHEM CO.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

3-METHYL-L-HISTIDINE N-HYDRATE

Cas:368-16-1

Min.Order:0

Negotiable

Type:Trading Company

inquiry

LEAP CHEM Co., Ltd.

Best Seller, High Quality, Competitive Price, Fast Delivery, Quick ResponseAppearance:powder, or liquid Storage:Stored in room temperature, ventilated place Package:Bottle, barrel, cargo, container, etc. Application:Pharmaceuticals, intermediates, AP

3-Methyl-L-histidine

Cas:368-16-1

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Amadis Chemical Co., Ltd.

1.Professional synthesis laboratory and production base. 2.Strong synthesis team and service team. 3.Professional data management system. 4.We provide the professional test date and product information ,ex. HNMR ,CNMR,FNMR, HPLC/G

3-methylhistidine

Cas:368-16-1

Min.Order:10 Milligram

Negotiable

Type:Lab/Research institutions

inquiry

HENAN SUNLAKE ENTERPRISE CORPORATION

3-METHYL-L-HISTIDINE N-HYDRATE

Cas:368-16-1

Min.Order:1 Metric Ton

Negotiable

Type:Trading Company

inquiry

Changzhou Extraordinary Pharmatech co.,LTD

Changzhou Extraordinary Pharmatech co., LTD. As a leading chemical manufacturer and supplier in China.DAS authentication is passed.We can provide the popular precursor chemicals, we have our own strong R & D team, have our own laboratories and fa

H-His(3-Me)-OH

Cas:368-16-1

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Synthetic route

3-methyl-5-(phenylthio)-L-histidine
141524-71-2

3-methyl-5-(phenylthio)-L-histidine

3-methyl-L-histidine
368-16-1

3-methyl-L-histidine

Conditions
ConditionsYield
With water; nickel In ethanol for 8h; Heating;87%
3-methyl-5-(1-naphthalenylthio)-L-histidine
141524-84-7

3-methyl-5-(1-naphthalenylthio)-L-histidine

3-methyl-L-histidine
368-16-1

3-methyl-L-histidine

Conditions
ConditionsYield
With water; nickel In ethanol for 8h; Heating;83%
L-histidine
71-00-1

L-histidine

methyl iodide
74-88-4

methyl iodide

A

3-methyl-L-histidine
368-16-1

3-methyl-L-histidine

B

His(1-CH3)
332-80-9

His(1-CH3)

Conditions
ConditionsYield
With ammonia; sodium
Nα,Nα-phthaloyl-L-histidine-methyl ester
65092-36-6

Nα,Nα-phthaloyl-L-histidine-methyl ester

methyl iodide
74-88-4

methyl iodide

3-methyl-L-histidine
368-16-1

3-methyl-L-histidine

Conditions
ConditionsYield
With N,N-dimethyl-formamide und anschliessendes Erwaermen mit wss.HCl;
trimethoxonium tetrafluoroborate
420-37-1

trimethoxonium tetrafluoroborate

N(α)-benzyloxycarbonyl-N(τ)-(4-tolylsulphonyl)-L-histidine methyl ester
95485-21-5

N(α)-benzyloxycarbonyl-N(τ)-(4-tolylsulphonyl)-L-histidine methyl ester

3-methyl-L-histidine
368-16-1

3-methyl-L-histidine

Conditions
ConditionsYield
With hydrogenchloride 1.) methylene dichloride, 24 h, room temp., 2.) reflux, 24 h; Multistep reaction;
imbricatine
105372-70-1

imbricatine

(1S,3S)-6,8-Dihydroxy-1-(4-hydroxy-benzyl)-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic acid
105372-72-3, 133761-44-1

(1S,3S)-6,8-Dihydroxy-1-(4-hydroxy-benzyl)-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic acid

B

3-methyl-L-histidine
368-16-1

3-methyl-L-histidine

Conditions
ConditionsYield
With nickel for 1h; Heating;A 8 mg
B n/a
With nickel for 1h; Heating;
N(α)-benzyloxycarbonyl-N(τ)-piperidinocarbonyl-L-histidine methyl ester
20793-93-5

N(α)-benzyloxycarbonyl-N(τ)-piperidinocarbonyl-L-histidine methyl ester

methyl iodide
74-88-4

methyl iodide

3-methyl-L-histidine
368-16-1

3-methyl-L-histidine

Conditions
ConditionsYield
With hydrogenchloride 1.) (DMF), 24 h, room temp., 2.) reflux, 24 h; Multistep reaction;
(S)-2-Benzyloxycarbonylamino-3-(1-tert-butoxymethyl-1H-imidazol-4-yl)-propionic acid methyl ester
99523-92-9

(S)-2-Benzyloxycarbonylamino-3-(1-tert-butoxymethyl-1H-imidazol-4-yl)-propionic acid methyl ester

methyl iodide
74-88-4

methyl iodide

3-methyl-L-histidine
368-16-1

3-methyl-L-histidine

Conditions
ConditionsYield
With hydrogenchloride 1.) (DMF), 24 h, room temp., 2.) reflux, 24 h; Multistep reaction;
N(α)-benzyloxycarbonyl-N(ϖ)-t-butoxymethyl-L-histidine methyl ester
90653-43-3

N(α)-benzyloxycarbonyl-N(ϖ)-t-butoxymethyl-L-histidine methyl ester

methyl iodide
74-88-4

methyl iodide

A

3-methyl-L-histidine
368-16-1

3-methyl-L-histidine

B

His(1-CH3)
332-80-9

His(1-CH3)

Conditions
ConditionsYield
With hydrogenchloride 1.) (DMF), 24 h, room temp., 2.) reflux, 24 h; Multistep reaction;
N(α)-benzyloxycarbonyl-N(ϖ)-(2-trimethylsilylethoxy)methyl-L-histidine methyl ester
99523-90-7

N(α)-benzyloxycarbonyl-N(ϖ)-(2-trimethylsilylethoxy)methyl-L-histidine methyl ester

methyl iodide
74-88-4

methyl iodide

A

3-methyl-L-histidine
368-16-1

3-methyl-L-histidine

B

His(1-CH3)
332-80-9

His(1-CH3)

Conditions
ConditionsYield
With hydrogenchloride 1.) (DMF), 24 h, room temp., 2.) reflux, 24 h; Multistep reaction;
N(α)-benzyloxycarbonyl-N(τ)-(2-methoxyethoxy)methyl-L-histidine methyl ester
99523-89-4

N(α)-benzyloxycarbonyl-N(τ)-(2-methoxyethoxy)methyl-L-histidine methyl ester

methyl iodide
74-88-4

methyl iodide

3-methyl-L-histidine
368-16-1

3-methyl-L-histidine

Conditions
ConditionsYield
Multistep reaction;
N(α)-benzyloxycarbonyl-N(τ)-(2-trimethylsilylethoxy)methyl-L-histidine methyl ester
99523-91-8

N(α)-benzyloxycarbonyl-N(τ)-(2-trimethylsilylethoxy)methyl-L-histidine methyl ester

methyl iodide
74-88-4

methyl iodide

A

3-methyl-L-histidine
368-16-1

3-methyl-L-histidine

B

His(1-CH3)
332-80-9

His(1-CH3)

Conditions
ConditionsYield
With hydrogenchloride 1.) (DMF), 24 h, room temp., 2.) reflux, 24 h; Multistep reaction;
N-acetyl-N3-methyl-L-histidine
37841-04-6

N-acetyl-N3-methyl-L-histidine

3-methyl-L-histidine
368-16-1

3-methyl-L-histidine

Conditions
ConditionsYield
With (2)H8O4Pd(2+); deuteroperchloric acid In water-d2 at 40℃; Rate constant;
aneserine

aneserine

3-methyl-L-histidine
368-16-1

3-methyl-L-histidine

Conditions
ConditionsYield
With sulfuric acid; water
1-methyl-4-bromo-5-hydroxymethyl-1H-imidazole
141524-73-4

1-methyl-4-bromo-5-hydroxymethyl-1H-imidazole

3-methyl-L-histidine
368-16-1

3-methyl-L-histidine

Conditions
ConditionsYield
Multi-step reaction with 8 steps
1: 96 percent / active γ-MnO2 / CHCl3 / 1 h / Heating
2: 83 percent / NaH / dimethylformamide / 3 h / 100 °C
3: 97 percent / NaBH4 / methanol / 0.33 h / Ambient temperature
4: 98 percent / SOCl2 / 1.) 0 deg C, 30 min, 2.) RT, 30 min
5: 1.) butyllithium / 1.) hexane, THF, -78 deg C, 10 min, 2.)a) hexane, THF, -78 deg C, 1 h, b) -50 deg C, 20 h
6: 84 percent / 0.25 N aq. HCl / methanol / 1.5 h / Ambient temperature
7: 86 percent / 6 N aq. HCl / 1 h / Heating
8: 83 percent / H2O / Raney Ni / ethanol / 8 h / Heating
View Scheme
Multi-step reaction with 8 steps
1: 96 percent / active γ-MnO2 / CHCl3 / 1 h / Heating
2: 73 percent / NaH / dimethylformamide / 3 h / 120 °C
3: 97 percent / NaBH4 / methanol / 0.5 h / Ambient temperature
4: 97 percent / SOCl2 / 1.) 0 deg C, 30 min, 2.) RT, 30 min
5: 1.) butyllithium / 1.) hexane, THF, -78 deg C, 15 min, 2.)a) hexane, THF, -78 deg C, 1 h, b) -50 deg C, 18 h
6: 98 percent / 0.25 N aq. HCl / methanol / 1.5 h / Ambient temperature
7: 83 percent / 6 N aq. HCl / 1 h / Heating
8: 87 percent / H2O / Raney Ni / ethanol / 8 h / Heating
View Scheme
4-bromo-1-methyl-1H-imidazole-5-carbaldehyde
141524-74-5

4-bromo-1-methyl-1H-imidazole-5-carbaldehyde

3-methyl-L-histidine
368-16-1

3-methyl-L-histidine

Conditions
ConditionsYield
Multi-step reaction with 7 steps
1: 83 percent / NaH / dimethylformamide / 3 h / 100 °C
2: 97 percent / NaBH4 / methanol / 0.33 h / Ambient temperature
3: 98 percent / SOCl2 / 1.) 0 deg C, 30 min, 2.) RT, 30 min
4: 1.) butyllithium / 1.) hexane, THF, -78 deg C, 10 min, 2.)a) hexane, THF, -78 deg C, 1 h, b) -50 deg C, 20 h
5: 84 percent / 0.25 N aq. HCl / methanol / 1.5 h / Ambient temperature
6: 86 percent / 6 N aq. HCl / 1 h / Heating
7: 83 percent / H2O / Raney Ni / ethanol / 8 h / Heating
View Scheme
Multi-step reaction with 7 steps
1: 73 percent / NaH / dimethylformamide / 3 h / 120 °C
2: 97 percent / NaBH4 / methanol / 0.5 h / Ambient temperature
3: 97 percent / SOCl2 / 1.) 0 deg C, 30 min, 2.) RT, 30 min
4: 1.) butyllithium / 1.) hexane, THF, -78 deg C, 15 min, 2.)a) hexane, THF, -78 deg C, 1 h, b) -50 deg C, 18 h
5: 98 percent / 0.25 N aq. HCl / methanol / 1.5 h / Ambient temperature
6: 83 percent / 6 N aq. HCl / 1 h / Heating
7: 87 percent / H2O / Raney Ni / ethanol / 8 h / Heating
View Scheme
1-methyl-4-(phenylthio)-1H-imidazole-5-methanol
141524-76-7

1-methyl-4-(phenylthio)-1H-imidazole-5-methanol

3-methyl-L-histidine
368-16-1

3-methyl-L-histidine

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1: 97 percent / SOCl2 / 1.) 0 deg C, 30 min, 2.) RT, 30 min
2: 1.) butyllithium / 1.) hexane, THF, -78 deg C, 15 min, 2.)a) hexane, THF, -78 deg C, 1 h, b) -50 deg C, 18 h
3: 98 percent / 0.25 N aq. HCl / methanol / 1.5 h / Ambient temperature
4: 83 percent / 6 N aq. HCl / 1 h / Heating
5: 87 percent / H2O / Raney Ni / ethanol / 8 h / Heating
View Scheme
1-methyl-4-(phenylthio)-1H-imidazole-5-carbaldehyde
141524-75-6

1-methyl-4-(phenylthio)-1H-imidazole-5-carbaldehyde

3-methyl-L-histidine
368-16-1

3-methyl-L-histidine

Conditions
ConditionsYield
Multi-step reaction with 6 steps
1: 97 percent / NaBH4 / methanol / 0.5 h / Ambient temperature
2: 97 percent / SOCl2 / 1.) 0 deg C, 30 min, 2.) RT, 30 min
3: 1.) butyllithium / 1.) hexane, THF, -78 deg C, 15 min, 2.)a) hexane, THF, -78 deg C, 1 h, b) -50 deg C, 18 h
4: 98 percent / 0.25 N aq. HCl / methanol / 1.5 h / Ambient temperature
5: 83 percent / 6 N aq. HCl / 1 h / Heating
6: 87 percent / H2O / Raney Ni / ethanol / 8 h / Heating
View Scheme
1-methyl-4-(1-naphthalenylthio)-1H-imidazole-5-methanol
141524-80-3

1-methyl-4-(1-naphthalenylthio)-1H-imidazole-5-methanol

3-methyl-L-histidine
368-16-1

3-methyl-L-histidine

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1: 98 percent / SOCl2 / 1.) 0 deg C, 30 min, 2.) RT, 30 min
2: 1.) butyllithium / 1.) hexane, THF, -78 deg C, 10 min, 2.)a) hexane, THF, -78 deg C, 1 h, b) -50 deg C, 20 h
3: 84 percent / 0.25 N aq. HCl / methanol / 1.5 h / Ambient temperature
4: 86 percent / 6 N aq. HCl / 1 h / Heating
5: 83 percent / H2O / Raney Ni / ethanol / 8 h / Heating
View Scheme
1-methyl-4-(1-naphthalenylthio)-1H-imidazole-5-carbaldehyde
141524-61-0

1-methyl-4-(1-naphthalenylthio)-1H-imidazole-5-carbaldehyde

3-methyl-L-histidine
368-16-1

3-methyl-L-histidine

Conditions
ConditionsYield
Multi-step reaction with 6 steps
1: 97 percent / NaBH4 / methanol / 0.33 h / Ambient temperature
2: 98 percent / SOCl2 / 1.) 0 deg C, 30 min, 2.) RT, 30 min
3: 1.) butyllithium / 1.) hexane, THF, -78 deg C, 10 min, 2.)a) hexane, THF, -78 deg C, 1 h, b) -50 deg C, 20 h
4: 84 percent / 0.25 N aq. HCl / methanol / 1.5 h / Ambient temperature
5: 86 percent / 6 N aq. HCl / 1 h / Heating
6: 83 percent / H2O / Raney Ni / ethanol / 8 h / Heating
View Scheme
3-methyl-5-(phenylthio)-L-histidine methyl ester
141524-79-0

3-methyl-5-(phenylthio)-L-histidine methyl ester

3-methyl-L-histidine
368-16-1

3-methyl-L-histidine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 83 percent / 6 N aq. HCl / 1 h / Heating
2: 87 percent / H2O / Raney Ni / ethanol / 8 h / Heating
View Scheme
3-methyl-5-(1-naphthalenylthio)-L-histidine methyl ester
141524-83-6

3-methyl-5-(1-naphthalenylthio)-L-histidine methyl ester

3-methyl-L-histidine
368-16-1

3-methyl-L-histidine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 86 percent / 6 N aq. HCl / 1 h / Heating
2: 83 percent / H2O / Raney Ni / ethanol / 8 h / Heating
View Scheme
5-(chloromethyl)-1-methyl-4-(phenylthio)-1H-imidazole hydrochloride

5-(chloromethyl)-1-methyl-4-(phenylthio)-1H-imidazole hydrochloride

3-methyl-L-histidine
368-16-1

3-methyl-L-histidine

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: 1.) butyllithium / 1.) hexane, THF, -78 deg C, 15 min, 2.)a) hexane, THF, -78 deg C, 1 h, b) -50 deg C, 18 h
2: 98 percent / 0.25 N aq. HCl / methanol / 1.5 h / Ambient temperature
3: 83 percent / 6 N aq. HCl / 1 h / Heating
4: 87 percent / H2O / Raney Ni / ethanol / 8 h / Heating
View Scheme
5-(chloromethyl)-1-methyl-4-(1-naphthalenylthio)-1H-imidazole hydrochloride

5-(chloromethyl)-1-methyl-4-(1-naphthalenylthio)-1H-imidazole hydrochloride

3-methyl-L-histidine
368-16-1

3-methyl-L-histidine

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: 1.) butyllithium / 1.) hexane, THF, -78 deg C, 10 min, 2.)a) hexane, THF, -78 deg C, 1 h, b) -50 deg C, 20 h
2: 84 percent / 0.25 N aq. HCl / methanol / 1.5 h / Ambient temperature
3: 86 percent / 6 N aq. HCl / 1 h / Heating
4: 83 percent / H2O / Raney Ni / ethanol / 8 h / Heating
View Scheme
(2R-trans)-2,5-dihydro-3,6-dimethoxy-2-(1-methylethyl)-5-<<1-methyl-4-(phenylthio)-1H-imidazol-5-yl>methyl>pyrazine
141524-78-9

(2R-trans)-2,5-dihydro-3,6-dimethoxy-2-(1-methylethyl)-5-<<1-methyl-4-(phenylthio)-1H-imidazol-5-yl>methyl>pyrazine

3-methyl-L-histidine
368-16-1

3-methyl-L-histidine

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 98 percent / 0.25 N aq. HCl / methanol / 1.5 h / Ambient temperature
2: 83 percent / 6 N aq. HCl / 1 h / Heating
3: 87 percent / H2O / Raney Ni / ethanol / 8 h / Heating
View Scheme
(2R-trans)-2,5-dihydro-3,6-dimethoxy-2-(1-methylethyl)-5-<<1-methyl-4-(1-naphthalenylthio)-1H-imidazol-5-yl>methyl>pyrazine
141524-82-5

(2R-trans)-2,5-dihydro-3,6-dimethoxy-2-(1-methylethyl)-5-<<1-methyl-4-(1-naphthalenylthio)-1H-imidazol-5-yl>methyl>pyrazine

3-methyl-L-histidine
368-16-1

3-methyl-L-histidine

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 84 percent / 0.25 N aq. HCl / methanol / 1.5 h / Ambient temperature
2: 86 percent / 6 N aq. HCl / 1 h / Heating
3: 83 percent / H2O / Raney Ni / ethanol / 8 h / Heating
View Scheme
Z-His-OMe
15545-10-5

Z-His-OMe

3-methyl-L-histidine
368-16-1

3-methyl-L-histidine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 39 percent / triethylamine / benzene / 2 h / Heating
2: 2.) 'constant boiling' hydrochloric acid / 1.) (DMF), 24 h, room temp., 2.) reflux, 24 h
View Scheme
Multi-step reaction with 2 steps
1: 70 percent / pyridine / 24 h / Ambient temperature
2: 2.) 'constant boiling' hydrochloric acid / 1.) methylene dichloride, 24 h, room temp., 2.) reflux, 24 h
View Scheme
Multi-step reaction with 2 steps
1: 32 percent / triethylamine / CH2Cl2 / 2 h / Ambient temperature
View Scheme
Multi-step reaction with 2 steps
1: 27 percent / triethylamine / ethyl acetate / 1.) 0 deg C, 1 h, 2.) room temp., 6 h.
2: 2.) 'constant boiling' hydrochloric acid / 1.) (DMF), 24 h, room temp., 2.) reflux, 24 h
View Scheme
L-Histidine methyl ester
1499-46-3

L-Histidine methyl ester

3-methyl-L-histidine
368-16-1

3-methyl-L-histidine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: methanol / und anschliessendes Behandeln mit SOCl2 in Benzol
2: DMF / und anschliessendes Erwaermen mit wss.HCl
View Scheme
3-methyl-L-histidine
368-16-1

3-methyl-L-histidine

[αR-3H]-Nτ-methylhistamine
1205535-88-1

[αR-3H]-Nτ-methylhistamine

Conditions
ConditionsYield
With (1)H,(3)H-water; histidine decarboxylase; pyridoxal 5'-phosphate at 37℃; for 192h; pH=4.7; aq. phosphate buffer; Enzymatic reaction;81%
3-methyl-L-histidine
368-16-1

3-methyl-L-histidine

[αR-2H]-Nτ-methylhistamine
1205535-87-0

[αR-2H]-Nτ-methylhistamine

Conditions
ConditionsYield
With histidine decarboxylase; pyridoxal 5'-phosphate; water-d2 at 37℃; for 192h; pH=4.7; aq. phosphate buffer; Enzymatic reaction;66%
3-methyl-L-histidine
368-16-1

3-methyl-L-histidine

3-(tert-butyloxycarbonyl)-4,5-dihydro-1,3-oxazine-2,6-dione
357610-30-1

3-(tert-butyloxycarbonyl)-4,5-dihydro-1,3-oxazine-2,6-dione

C15H24N4O5

C15H24N4O5

Conditions
ConditionsYield
With sodium hydroxide In water at 0 - 10℃; for 0.5h; Solvent; Reagent/catalyst;65%
methanol
67-56-1

methanol

toluene-4-sulfonic acid
104-15-4

toluene-4-sulfonic acid

3-methyl-L-histidine
368-16-1

3-methyl-L-histidine

2-amino-3-(3-methyl-3H-imidazol-4-yl)-propionic acid methyl ester; compound with toluene-4-sulfonic acid

2-amino-3-(3-methyl-3H-imidazol-4-yl)-propionic acid methyl ester; compound with toluene-4-sulfonic acid

Conditions
ConditionsYield
for 24h; Heating;45%
bufotalin 3-hemisuberate p-nitrophenyl ester
61507-75-3

bufotalin 3-hemisuberate p-nitrophenyl ester

3-methyl-L-histidine
368-16-1

3-methyl-L-histidine

bufotalin 3-suberoyl-L-1-methylhistidine ester
95210-87-0

bufotalin 3-suberoyl-L-1-methylhistidine ester

Conditions
ConditionsYield
In pyridine; water for 12h; Ambient temperature;16 mg
[13C]-formaldehyde
3228-27-1

[13C]-formaldehyde

3-methyl-L-histidine
368-16-1

3-methyl-L-histidine

C7(13)C2H15N3O2

C7(13)C2H15N3O2

Conditions
ConditionsYield
With sodium cyanoborohydride In acetate buffer at 37℃; for 0.166667h; pH=5.3;
paraformaldehyde-d2
1664-98-8

paraformaldehyde-d2

3-methyl-L-histidine
368-16-1

3-methyl-L-histidine

C9H11(2)H4N3O2

C9H11(2)H4N3O2

Conditions
ConditionsYield
With sodium cyanoborohydride In acetate buffer at 37℃; for 0.166667h; pH=5.3;
formaldehyd
50-00-0

formaldehyd

3-methyl-L-histidine
368-16-1

3-methyl-L-histidine

C9H15N3O2

C9H15N3O2

Conditions
ConditionsYield
With sodium cyanoborohydride In acetate buffer at 37℃; for 0.166667h; pH=5.3;

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